LEMOYNE-OWEN COLLEGE
DIVISION OF NATURAL SCIENCE, MATHEMATICS
AND COMPUTER SCIENCE
SYLLABUS FOR GENETICS (BIOL 303)
PREREQUISITE: BIOL 103, 104 and CHEM 101, 102
TEXT: ESSENTIAL GENETICS (5th Edition) By DANIEL L. HARTL & ELIZABETH W.
JONES. BY JONES AND BARTLETT PUBL.
A Test Book is required of each student.
Instructor: Dr. Mohammed R. Uddin (Room GOH 300E, ph. ext. 1388)
Office Hours: Posted on office door.
Course Description: This is a course designed for Biology majors. It includes Mendelian
genetics, Sex determination, Linkage and crossing over, Chemical nature of genes, Gene
expression, Gene cloning and biotechnological application of genetics.
Objectives: The students will acquire a comprehensive background in the rules of inheritance
and the mechanism by which genes directs growth development and appearance of an organism.
This course is required for preparing students pursuing careers in biology, medicine and related
biomedical and health related fields. The students will gain an understanding about the important
contribution genetics has been making in medicine, food production and environmental
remediation. In this course students will develop analytical and critical thinking skills, testwiseness, and reading comprehension of scientific literature. Students will demonstrate the
scientific communication skills.
Classroom Procedure: There will be two 75 minute lectures and a 150 minute lab per week.
Students are required to complete all the assignments from both lecture and lab each week.
Course Requirements: All students are required to take all tests and quizzes given, do all the lab
activities, turn in a lab report for each lab performed, and turn in all assignments on time.
Class Policies:
A. Attendance/Tardiness Policy: Students are expected to be in class for the whole period, as
schedule. Institutional Attendance Policy, as stated below, will be applied:
"The final letter grade may be lowered by one letter if the unexcused absences include or exceed
15% of the scheduled class meetings and changes to "F" if the unexcused absences equal or
exceed 20% of the scheduled class meetings."
Three unexcused tardiness will be considered equivalent to one unexcused absence. An absence
or tardiness may be excused only if the student experienced a genuine emergency as certified by
an appropriate authority such as a doctor, police officer, court clerk, instructor or coach, etc.or a
schedule conflict with a mandatory college activity,
B. Grading
***Four Tests 4 x 100
C. Grading Scale:
= 450 points
90% or above = A
Final Exam
=450
80% -89%
=B
Attendance & Class Participation
=50 points
70%-79%
=C
Special Project__________________=50
60%-69%
=D
Total
Below 60%
=F
= 1000 points
*** Number of Tests are tentative ( Would be determined based on class learning dynamics)
D. Examinations
Tentatively four lecture tests and two quiz will be given during the semester. There will be no
make-up test, except for an excused absence as stated on the previous page under the
"Attendance/Tardiness Policy". However, it is the student’s responsibility to contact the
instructor as soon as the emergency situation in under control and request to arrange a make-up
test date. Of the four lecture tests, the one with the lowest score may be dropped, and the final
grade will be calculated based on the other three tests and the remaining grading as shown above.
If a test is missed, the missed test will be considered as the lowest score. Cheating in any test,
quiz, or exam will result in zero points on the tests, quiz, or exams.
COURSE OUTLINE-GENETICS
I. INTRODUCTION
1. Definition and scope of genetics
2. The three general areas of genetics
II. MENDELISM AND CHROMOSOMAL THEORY
1. Mendel’s experiments
2. Nomenclature
3. Multiple alleles
4. Genotypic interaction
III. MITOSIS AND MEIOSIS
1. Chromosomes
2. Mitosis
3. Meiosis
4. Meiosis in animals
5. Chromosomal theory of heredity
VI. LINKAGE AND MAPPING IN EUKARYOTES
1. Diploid mapping
2. Haploid mapping
V. Cytogenetics
1. Variation in chromosome structure
2. Variation in chromosome number
3. Aneuploidy in human beings
VI. LINKAGE AND MAPPING IN PROKARYOTES AND VIRUSES
1. Bacteria and virus in genetics research
2. Bacteria phenotypes
3. Viral phenotypes
4. Sexual processes in bacteria and viruses
VIII. CHEMISTRY OF THE GENE
1. Nature of the genetic material
2. Nucleic acids
3. DNA replication
4. Eukaryotic DNA replication
XI. GENE EXPRESSION
1. Genetic Code
2. Types of RNA
3. Transcription
4. Translation
5. Eukaryotic transcription
X. GENTIC ENGINEERING AND GENOME ANALYSIS
1. Restriction endonucleases
2. Vectors
3. Probing for a specific gene
4. Eukaryoric vectors
5. Restriction mapping
XII. DNA SEQUENCING
1. Dideoxy method
2. Application of gene cloning