ANNEX B
LONDON METROPOLITAN UNIVERSITY
Module Specification template
Section One: ABOUT THE MODULE
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Module title
Haemoglobinopathies
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Module code
BM7113DL
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Module level and credit rating
Level 7
10
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Faculty
Life Sciences
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School/Subject Discipline
School of Human Sciences
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Teaching locations
north
[click to select location]
[click to select location]
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Teaching period
[click to select teaching period]
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Pattern of attendance
Distance Learning
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Required prior learning
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Module description
BM7113DL
Haemoglobinopathies
This module provides an understanding and knowledge of the theory and practice of haematology.
Examining the different elements that constitute blood in normal and diseased states, investigating the
causes and diagnosis of anaemias, haemoglobinopathies and thalassaemias, haematological
malignancy, haemostasis and thrombosis.
Semester: Autumn, Spring, Summer (10 credit)
Required prior Learning:
Assessment: Quizzes (500 words) (30%), reflective learning log (500 words) (30%), coursework (1000
words) (40%)
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Module aims
The aims of this module are aligned with the qualification descriptors within the Quality Assurance
Agency’s Framework for Higher Education Qualifications. To provide, through in depth study,
knowledge and understanding of the theory and practice of haematology as well as to reinforce
analytical, evaluative and communication skills. It will also enable students to research a topical issue
and present it at an appropriate level and to reflect on the topics studied and their application in
biomedical practice.
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Module learning outcomes
On successful completion of this module students will be able to:
1. Describe the laboratory processes for haemoglobinopathy screening and diagnosis nature, relate
genetic theory to laboratory and clinical practice, including awareness of factors affecting prenatal
diagnosis, antenatal/newborn screening processes, risks associated with the sample reagents, or
method and other tests indicated by the outcome of the analysis and associated ethical issues.
2. Understand principles of quality control, quality assurance, failsafe procedures, screening policies
and diagnosis of haemoglobinopathies, and critically interpret and evaluate information case studies,
reporting and communicating the results
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15
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3. Demonstrate through the reflective learning journal that the student has reflected on their own
performance as an independent professional learner with a focus on their practice.
Indicative syllabus – for full details see section C in Module Booklet
This module provides an understanding and knowledge of the theory and practice of
haemoglobinopathy screening, diagnosis and ethical issues arising. Aetiology, Epidemiology, Genetics
and Pathophysiology of Haemoglobinopathies (focusing on Thalassaemia(Thal) and Sickle Cell (SC))
Counselling, management and treatment considerations. Categorisation of thalassemia’s, correlation of
the results of laboratory testing with specific thalassaemias and haemoglobinopathies.
Workshop: a) Case review and data analysis, SC and Beta Thal Major, antenatal and newborn screening,
Laboratory diagnosis and interpretation exercises, - inexperienced NHS haematology staff and MSc
Blood Science students.
OR b) Review of updates to laboratory handbook, Case review and data analysis, SC and Beta Thal
Major, antenatal and newborn screening, ethical issues, New technologies (Mass Spectrometry,
Capillary electrophoresis, other equipment as appropriate), Case study presentations, Unusual
Haemoglobinopathies. – Experienced Haematology Staff.
OR c) Review of Haemoglobinopathies, recent updates, Newborn screening programme outcomes,
antenatal and newborn screening, ethical issues, Blood Spot programme, Case study presentation and
analysis. – newborn screening staff.
Indicative bibliography and key on-line resources – for full details see section D in Module Booklet
Bains B J. (2006) Haemoglobinopathy Diagnosis 2nd Ed. Blackwell.
Bain B J, Bates I, Laffan, MA, Lewis SM. (2006) Dacie and Lewis Practical Haematology 11th Ed. Churchill
Livingstone.
Daniel Y, Henthorn J. (2012) Sickle Cell and Thalassaemia – Handbook for laboratories 3rd Edn. NHS
Okpala I. (2004) Practical Management of Haemoglobinopathies. Wiley-Blackwell
Ryan K, Bain BJ, Worthington D, James J, Plews D, Mason A, Roper D, Rees DC, De La Salle B, Streetly A.
(2010) Significant haemoglobinopathies: guidelines for screening and diagnosis. BJH 149: 1; 35-49.
Trent RJA. (2006) Diagnosis of Haemoglobiopathies, Clin Biochem Rev. 27:1; 27-38.
Learning and Teaching strategy for the module including approach to blended learning, students’ study
responsibilities and opportunities for reflective learning/pdp
Information pertaining to the subject matter will be presented through an integrated programme of
lectures and supporting exercises, together with some use of a problem-based learning approach and
the guided use of student-centred learning resources. Lectures will be used to provide a conceptual
framework. Student centred assignments and will enable students to reinforce and expand their
knowledge, and develop subject specific skills and competence.
Indicative learning and teaching hours for the module. Learning hours comprise face-to-face and virtual
contact hours plus self-managed and directed learning and time spent on placements (where relevant).
Method
Description and percentage of learning hours
Scheduled learning and teaching activities
Guided independent study
100 (100%)
TOTAL LEARNING HOURS FOR THE
100 hours
MODULE
Assessment strategy
The module will be formatively assessed by in-course online quizzes (30%) and two coursework
components. A reflective learning log (30%; 1500 words) and a written assignment (40%; 1500
words). Criteria for assessment will include an understanding of the subject matter; an ability, both
orally and written, to explain, describe and discuss the work; completeness and conciseness of
written reports and essays with emphasis upon critical ability and scientific rigor. To pass the module
students need to achieve a minimum aggregate mark of 50%. There is a one day workshop session
Component
Quizzes
Learning outcomes
1
18
19
Reflective learning log
1,2
Written assignment
1,2,3
Arrangements for formative and summative feedback
Written feedback on the coursework will be given at the end of the module
Description of assessment items
Assessment
Method
Practical Exam
Coursework
Coursework
Workshop
attendance
Description of Item
On-line Quizzes (500 words)
Reflective learning log (1500
words)
Written assignment (ECA) (1000
words
One day work shop
Section Two: FACULTY USE
20 Nominated External Examiner
21 Nominated Module Leader at time of approval
22 Courses to which this module contributes and
whether Core or Option
%
weighting
Week
Due
If not pass on aggregate,
explain what is required to
pass the module
30
40
30
0
Compulsory attendance
Sheelagh Heugh
MSc Blood Science Optional Module
NHS Sickle Cell & Thalassaemia Screening
Programme
Section Three: OFFICIAL USE AND CODES – responsibility for completion is as indicated
23 Original date of approval (QEU)
24 Module approved to run from (QEU)
25 Revision date (specify cohort) (QEU)
26 Module specification version number (QEU)
27 SITS Mark Scheme (Academic Registry)
28 Subject Standards Board Name (Academic
Registry)