Genetic Inheritance, Evolution, Profiling and Genetic Engineering Self-Assessment Genetic Inheritance, Evolution, Profiling and Genetic Engineering 1 Define gamete 2 Outline gamete formation 3 Give the function of gametes in sexual reproduction 4 Define fertilisation 5 Define allele 6 Differentiate between the terms homozygous and heterozygous. 7 Differentiate between genotype and phenotype 8 Differentiate between dominant and recessive 9 Define incomplete dominance 10 Show the inheritance to the F1 generation in a cross involving Homozygous parents (Show the genotypes of parents, gametes and offspring) Show the inheritance to the F1 generation in a cross involving Heterozygous parents (Show the genotypes of parents, gametes and offspring) Show the inheritance to the F1 generation in a cross involving Sex determination XX x XY (Show the genotypes of parents, gametes and offspring) Describe the work of Gregor Mendel leading to the expression of his findings in two laws 11 12 13 14 State the Law of Segregation 15 Explain the Law of Segregation 16 State the Law of Independent Assortment 17 Explain the Law of Independent Assortment 18 Show the inheritance to the second filial generation (F2) of two unlinked traits using the Punnet square technique 19 Define linkage 20 Explain the change in 1:1:1:1 probability for a dihybrid heterozygote crossed with a dihybrid recessive organism. (Knowledge of crossing over is not required). 21 Explain sex linkage of genes 22 Give examples of common sex linked traits Red Orange Green 23 Explain non-nuclear inheritance 24 Identify two causes of variation 25 Identify two types of mutations 26 Give an example of each type of mutation 27 List two agents responsible for increased mutation rates 28 Define evolution 29 30 Outline the Darwin and Wallace Theory of natural selection Discuss the evidence of evolution from any one source (e.g. fossils, comparative anatomy or the study of embryos) 31 Define the process of DNA profiling 32 Outline the four stages involved in DNA profiling 33 Give any two applications of DNA profiling 34 Define Genetic Screening 35 Give a use for genetic screening 36 Describe the steps involved in the isolation of DNA 37 Draw diagrams to illustrate this activity 38 Can you define genetic engineering? 39 Do you understand that DNA from different organisms can be joined together? 40 Can you give examples of this? 41 Do you know what a restriction enzyme is and does? 42 Can you explain the process of isolation? 43 Can you explain the process of cutting? 44 Can you explain the process of insertion? 45 Can you explain the process of transformation? 46 Can you explain the process of expression? 47 Can you outline three applications of genetic engineering? 48 Can you discuss the ethical issues associated with GE?