Espinoza 1 Guadalupe Espinoza UWP 1 12/8/2013 WC: 1342 Growing Peanut Allergy Epidemic Everyday millions of Americans fall victims to the allergic reactions produced by their own bodies. An allergy is when one’s immune system recognizes a foreign substance whether it be food, dust, pollen and it has a hypersensitive reaction to it. The growing number of people with allergies has significantly grown over the past few years. More specifically the allergy to peanuts has become a growing phenomenon. “Peanut allergy is one of the most serious of the immediate hypersensitivity reactions to foods. Its persistence and severity and appears to be a growing problem” (Sampson 2002). A recent study conducted showed that “1.3% of American adults in the U.S are allergic to peanuts or some other kind of tree nut” (Sicherer, Munoz-Furlong, Burks, Sampson 1999). Experts say that 80% of emergency room anaphylactic visits were peanut related. Anaphylaxis is the state in which one’s air passageways begin to swell so badly it makes it difficult for one to breathe. “Due to the persistence of the reaction and the lack of effective treatment, peanut specific immunotherapy is currently being examined as a treatment option”(2002). Many times people with such life threatening allergies carry an epinephrine pen (epi-pen), which has an antihistamine drug that reduces the swelling of airways. Some researchers believe that heredity and what a mother eats during pregnancy can influence a child’s development of allergies. Numerous studies have began to question the connection of heredity and maternal diets during pregnancy to the growing Espinoza 2 prevalence of children found with peanut allergies the experimental treatments of immunotherapy and the quality of life these children experience will also be examined when relating the growing number of peanut allergies found in children. Allergies to peanuts are very often the cause of fatal and nearly fatal food related anaphylaxis. During a study that was conducted to examine the similarities in allergies between different generations it was found that “peanut allergies were increasingly by successive generations”(Haourihane, Dean, Warner 1996). Many subjects of the study showed a similar if not the same allergy as that experienced by their previous generation of family members. Children with allergies after a questionnaire found that they shared the same or similar allergies to grandparents. The study also showed a higher rate of allergies between siblings. “Peanut allergy affects 7% of siblings of people with peanut allergy”(1996). It was more common to see siblings with the same allergies to both food and other substances. The study also showed that out of the number of parents that shared the same allergy as their child most of them were the mothers. “Atopy was more common in maternal relatives of allergic subjects than paternal relatives”(1996). The similarity in allergies between mother and child was quite prevalent and as researchers suggested it goes beyond the shared genetic make up and might in fact be related to the mother’s diet during pregnancy. A mother’s diet can influence many health factors for a child when pregnant. Everything consumed goes through both the mother and fetus. The vital connection that is the umbilical cord is the lifeline for the fetus. “Mothers of allergic children reported to have consumed little to none of the allergen during pregnancy”(1996). The reasoning behind the child developing allergens can be related to the fact that their body is not Espinoza 3 accustomed to breaking down the proteins and enzymes of the substance. When the allergen is finally introduced the body can have a difficult time absorbing the substance, which if not broken down successfully, can result in some sort of negative hypersensitive reaction. “Consumption of peanuts while pregnant of breast feeding reported a significantly lower number of children with allergies”(1996). This direct relationship between the mother’s diet and the child’s development of allergies goes on to show the influence the food ingested during pregnancy can have life long effects on the fetus. Mothers that reported not consuming peanuts had a higher number of children with allergies to the substance. The lack of experience their bodies have with breaking down the substance is clearly related the mother not introducing the substance to the fetus. The course of treatment when dealing with the peanut allergy can also influence the severity of one’s reaction when coming in contact with the substance. Peanuts and peanut products are the most common foods responsible for foodinduced anaphylaxis. The allergy to peanuts is one that is extremely rare to overcome. “Patients rarely loose sensitivity to peanuts”(Oppenheimer, Nelson, Bock, Christensen, Donald, Leung 1989). Once hypersensitivity to peanuts presents itself it remains indefinitely. A peanut allergy usually presents itself early in life and is battled with for the remainder of the patient’s life. “Currently there are no curative therapies for peanut allergy or other food allergies”(1989). The only treatment guaranteed to work is the strict avoidance of peanuts. The stress behind having to constantly fear their allergen can cause patients to go to extremes. When exposure does occur the only viable treatment is rush supportive treatment such as an epi-pen. Rush immunotherapy has been investigated as an experimental course of treatment. This treatment includes the injecting of the allergen Espinoza 4 into the skin and then continuously increasing the dosage to build resistance. “Subjects received increasing doses of subcutaneous injections to determine skin reactivity over a course of 60 minute intervals for 5 days” (1989). Throughout the study there was a dramatic reduction in skin irritation as the body became accustomed to dealing with the allergen. This dramatic experimental treatment was engaged in by subjects in order to gain some sort of resistance to their allergen. The resistance established by the subjects although traumatic could save their life in the future if they were ever exposed to their allergen again. The built resistance can buy them vital minutes during an allergic reaction. Due to the increase in resistance cause by the experimental treatment patients found that they could have a more open diet that allowed a greater variety of foods. The extreme diets carried out by patients with allergies can often cause a constant uncertainty in their lives. “Peanut allergy patients are driven by forces them and their families to exercise extreme vigilance” (Primeau, Kaagan, Jospeh, Lim, Dufresne, Duffy, Prhcal, Clarke 2000). The quality of life behind dealing with this never-ending allergen often causes children to carry a psychological burden. Children examined in the study “reported a more significant disruption in their daily life activities” (2000). For these patients even the minute amount of peanuts ingested can have life threatening results. “Those with peanut allergies continue to experience constant uncertainty throughout their lives regarding the risk of accidental ingestion”(2000). With the constant mass production of food products it is often difficult to find product that are completely peanut free, this constant psychological distress can take a negative toll on the both the patient and their family. The severity behind their peanut allergy can have both financial and social strain that without a mastered routine can have life altering results. Espinoza 5 Works Cited Espinoza 6 1. Burks, W. (2003). Peanut allergy: a growing phenomenon. Journal of Clinical Investigation, 111(7), 950-952. 2. Grundy, J., Matthews, S., Bateman, B., Dean, T., & Arshad, S. H. (2002). Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. Journal of Allergy and Clinical Immunology, 110(5), 784-789. 3. Hourihane, J. O., Dean, T. P., & Warner, J. O. (1996). Peanut allergy in relation to heredity, maternal diet, and other atopic diseases: results of a questionnaire survey, skin prick testing, and food challenges. BMJ: British Medical Journal, 313(7056), 518. 4. Oppenheimer, J. J., Nelson, H. S., Bock, S. A., Christensen, F., & Leung, D. Y. (1992). Treatment of peanut allergy with rush immunotherapy. Journal of allergy and clinical immunology, 90(2), 256-262. 5. Primeau, M. N., Kagan, R., Joseph, L., Lim, H., Dufresne, C., Duffy, C., ... & Clarke, A. (2000). The psychological burden of peanut allergy as perceived by adults with peanut allergy and the parents of peanut-allergic children. Clinical and Experimental Allergy, 30(8), 1135-1143. 6. Sampson, H. A. (2002). Peanut allergy. New England Journal of Medicine, 346(17), 1294-1299. 7. Sicherer, S. H., Muñoz-Furlong, A., Burks, A., & Sampson, H. A. (1999). Prevalence of peanut and tree nut allergy in the US determined by a random digit dial telephone survey. Journal of Allergy and Clinical Immunology, 103(4), 559-562.