Topic: Population Questions/Main Ideas: What causes genetic variation in a population? Name: ____________________________ Date:_________________________ Objective: SWBAT understand what affects the phenotypes of populations. Population= A group of interbreeding individuals of a species in a given area Genetic Variations= increase in variability through mutations and gene shuffling 1. Mutations= any change in a sequence of DNA. - Do not always affect an organism‘s phenotype. Ex) Point mutation of a DNA codon from GGA to GGU will code for the same amino acid, glycine, which has no effect on the organism’s phenotype. - Many mutations produce changes in the organism’s phenotype, affecting its fitness (ability to survive and reproduce) and eventually changes in the gene pool. 2. Gene shuffling=bringing together a new combination of genes - Crossing over which occurs during the production of gametes. - Sexual reproduction which occurs during the production of the zygote. What does natural selection act on? What are three ways that natural selection affects populations? Natural selection acts on phenotypes, not act directly on genes. It determines which alleles are passed on from one generation to the next. Natural selection can affect the distributions of phenotypes in any of three ways: 1. Stabilizing Selection= When individuals near the center of the curve have higher fitness than individuals at either end of the curve, causing the graph to narrow. Ex) A mother bird would overheat small eggs and wouldn’t keep large eggs warm enough. The medium sized babies would survive. 2. Directional Selection= When individuals at one end of the curve have higher fitness than individuals in the middle or at the other end, causing the graph to shift to one side. Ex) When food became scarce, the finches with larger beaks were better able to survive and reproduce. Thus, the average size of the beaks increased. 3. Disruptive Selection= When individuals at the upper and lower ends of the curve have higher fitness than individuals near the middle, causing a dip in the graph Ex) There are only large nuts for birds with large beaks and tiny seeds available for birds with small beaks. If disruptive selection is strong enough and long enough, the single curve may split into two; creating two distinct phenotypes and possibly a different species. How do populations maintain genetic equilibrium? Gene pool= Common group of genes shared by a population that contains two or more alleles (or forms) of a certain gene for each trait. - Ex) A mouse population may have two alleles for fur color (B for black fur; b for brown fur). Relative allele frequency= the number of times that an allele occurs in a gene pool compared with the number of times other alleles occur. The Hardy-Weinberg Principle= allele frequencies in a population will remain constant unless one or more factors cause those frequencies to change. Genetic Equilibrium= allele frequencies remain constant from generation to generation. - Ex) In generation 1, there are 5 black mice and 3 brown mice; in generation 2, there are 15 black mice and 9 brown mice Five conditions are required to maintain genetic equilibrium: 1. Random mating 2. Large population 3. No movement into or out of the population 4. No mutations 5. No Natural Selection STOP- turn to your elbow partner and discuss How do you calculate genetic equilibrium? Summary: Is this seen in a human population? p2 + 2pq + q2 = 1 and p + q = 1 p = frequency of the dominant allele in the population Ex) T q = frequency of the recessive allele in the population Ex) t p2 = percentage of homozygous dominant individuals Ex) TT q2 = percentage of homozygous recessive individuals Ex) tt 2pq = percentage of heterozygous individuals Ex) Tt and tT