Biology Keystone – Eligible Content Cells and Cell Processes Basic Biological Principles Module 1, Anchor 1 1) characteristics common to all life: prokaryotes vs. eukaryotes 2) structure & function at biological levels of organization: organelles, cells, tissues, organs, organ systems, organisms dominant organelles: nucleus, cell membrane, mitochondrion, ER, ribosomes, lysosomes, golgi appartus The Chemical Basis for Life 1) 2) 3) 4) Module 1, Anchor 2 properties of water: freezing point, high specific heat, cohesion properties of carbon macromolecules: carbs, lipids, proteins, nucleic acids enzymes – catalysts affected by pH, temp, concentration Bioenergetics Module 1, Anchor 3 1) how cells process energy: plastids (chloroplasts) and mitochondria 2) energy transformations: photosynthesis, cellular respiration, role of ATP Homeostasis & Transport Module 1, Anchor 4 1) materials into, out of and throughout cells: cell membrane, passive and active transport, organelles (ER and golgi) 2) homeostasis: thermoregulation, water regulation, oxygen regulation Continuity and Unity of Life Cell Growth & Reproduction Module 2, Anchor 1 1) cell cycle: interphase, nuclear division (mitosis/meiosis), cytokinesis Genetics Module 2, Anchor 2 1) inheritance: DNA, genes, chromosomes, alleles 2) DNA replication and protein synthesis (transcription, translation, protein modification) 3) Mendelian and non-Mendelian patterns of inheritance: dominant, recessive, co-dominance, incomplete dominance, sex-linked, polygenic, and multiple alleles 4) more on inhert. patterns: crossing-over, nondisjunction, duplication, translocation, deletion, insertion, and inversion 5) genetic mutations may or may not affect phenotype (silent, nonsense, frame-shift) 6) genetic engineering: selective breeding, gene splicing, cloning, genetically modified organisms, gene therapy Theory of Evolution Module 2, Anchor 3 1) mechanisms of evolution: natural selection, isolating mechanisms, genetic drift, founder effect, migration, genetic mutations 2) evidence: fossils, anatomy, physiology, embryology, biochemistry, universal genetic code 3) hypothesis, theory, inference, law, principle, fact, observation Ecology Module 2, Anchor 4 1) organization: organism, population, community, ecosystem, biome, biosphere 2) biotic and abiotic factors of terrestrial and aquatic ecosystems 3) interactions in an ecosystem a) b) c) d) e) energy flow – food chains, food webs, energy pyramids biotic – competition, predation, symbiosis matter cycles – water, carbon, oxygen, nitrogen human disturbances – climate change, nonnative species, pollution, fires limiting factors – population dynamics, potential extinction