REVIEW NOTES FOR DNA and RNA REPLICATION/TRANSCRIPTION/TRANSLATION/PROTEIN SYNTHESIS The nucleic acid _____ stores and transmits the genetic information from one generation to the next. DNA is short for _____________________________________. DNA IS a long molecule made of subunits called ______________, each of which consists of three basic components - _________________ which is a 5-carbon sugar, a _______________ group and one of four ______________ _____________. DNA is a double stranded molecule with a shape called a ______________ ______________. The sides, or backbone, of this molecule are the sugar and phosphate components linked together by covalent bonds. The “rungs of the ladder” are the paired, ________ ____________. The four bases can only pair together with _______________ bonded to thymine and cytosine bonded to _____________. The bases pairs are held together by ________________ bonds. The sequences of these bases form a type of code or alphabet known as a _______ which codes for a specific protein and thus a specific trait. During mitotic cell division DNA is copied during a process called ____________. This takes place during the S stage of Interphase. A human cell contains more than 1 meter of DNA. Its fits inside the __________ of the cell by being tightly coiled around proteins called histones to form a fiber or strand-like structure called a __________. During cell division these strands become even more compact and are called _______________. During DNA replication the molecule is separated into two strands and two complimentary strands are created by following the rules of _________ _____. Genes are coded DNA instructions that control the production of ______________. The first step of using this code to assemble protein takes place in the ___________ of the cell. The genetic message is copied from DNA to a second nucleic acid known as _____. RNA is similar to DNA but there are three main differences in the compounds. (1) DNA is double stranded while RNA is generally _______ ________, (2) DNA has deoxyribose sugar and RNA has _____________sugar and (3) RNA contains ____________ in place of thymine. There are three main types of RNA: ____________RNA, ________________RNA and _____________RNA. The RNA that can leave the nucleus with the information from a gene is called __RNA or messenger RNA. The protein is assembled at a _____________ which is made of several dozen proteins and __RNA or ribosomal RNA. During the construction of the protein __________ a third type of RNA transfers the amino acid to the ribosome. This is known as ___RNA or ___________________RNA. mRNA is produced when a segment of DNA nucleotide sequence is copied during the process called________________. This mRNA then leaves the nucleus and travels to a ______________. Each group of three mRNA bases is called a _____. Each _________ specifies for a specific amino acid. While there are 64 possible codons, there are only _______ different amino acids. There is one codon for methionine – the start code and three codons that code for ‘stop’. This means that some amino acids have several codons. At the ribosome, the process of _______________ takes place and the message is ‘decoded’ to assemble the protein. tRNA brings the appropriate amino acid to the building site on the ribosome and assembles the amino acids into the proper sequence to produce the specific ________. Each tRNA is specific to one amino acid and it can only match the mRNA codon with its _________.