Unit 2 Math Practice ANSWERS Name________________________________ 1) The recombination frequency between gene A and gene B is 14.5% and the recombination frequency between gene A and gene C is 8.6%. If the order of these genes on a chromosome is B-A-C, then the approximate recombination frequency between gene B and gene C should be 23.1%. 2) Find the recombination frequency between two genes on the same chromosome in peas given the following crosses: P (true-breeders): rough – soft pea x smooth – hard pea F1: all offspring are rough – soft Test cross: rough – soft pea (from F1) x smooth – hard pea F2: 127 rough – soft 113 smooth – hard 17 rough – hard 9 smooth - soft Recombination frequency = 9.8% 3) In Drosophila, there is a dominant gene for gray body color and another dominant gene for normal wings. The recessive alleles of those two genes result in black body color and vestigial wings, respectively. Flies homozygous for gray body and normal wings were crossed with flies that had black bodies and vestigial wings. The F1 progeny were then test-crossed with the following results: Phenotype Gray body, normal wings Black body, vestigial wings Gray body, vestigial wings Black body, normal wings # Progeny 236 253 240 242 What is the recombination frequency for these two genes? 49.6% Would you say that these two genes are genetically linked? no Why/why not? 50% is “max” RF and is associated with normally-unlinked genes. RF %s of significantly less than 50% are necessary to ID genes as “linked” If they are linked, how many map units apart are they on the chromosome? 49.6 map units 4) Calculate the probability (in fraction form) that two parents with the following genotype combination: AaBBccDd x AabbCcDd will produce an offspring with the genotype combinations: a) aaBbCcDd 1/16 b) AABbccdd 1/32 c) AabbCcDD 0 5) In a certain species of flowering plant, the purple allele ‘A’ is dominant to the yellow allele ‘a’. A student performed a cross between a purple-flowered plant and a yellow-flowered plant. When planted, the 146 seeds that were produced from the cross matured into 87 plants with purple flowers and 59 plants with yellow flowers. Calculate the chi-squared value for the hypothesis that the purple-flowered parent was heterozygous for the flower-color gene. Give your answer to the nearest tenth. 5.4 Based on your result, the null hypothesis is rejected. (accepted/rejected) 6) A large ear of corn has including 271 Purple & Smooth kernels, 73 Purple & Shrunken kernels, 63 Yellow & Smooth kernels, and 26 Yellow & Shrunken kernels. This ear of corn was hypothesized to have been produced by a dihybrid cross (PpSs x PpSs.) Calculate the chi-squared value for the hypothesis that this particular ear of corn was the progeny of the dihybrid cross PpSs x PpSs. Give your answer to the nearest tenth. 8.0 Based on your result, the null hypothesis is rejected. (accepted/rejected) 7) A heterozygous red eyed female was crossed with a red eyed male. The results are shown below. Red eyes are sex-linked dominant to white. Determine the chi square value for this scenario. Round to the nearest hundredth. 6.83 Phenotype Red eyes White eyes p 0.05 0.01 1 3.84 6.64 2 5.99 9.32 # flies observed 134 66 3 7.82 11.34 Degrees of Freedom 4 5 9.49 11.07 13.28 15.09 6 12.59 16.81 7 14.07 18.48 8 15.51 20.09