#3
Smiler,
B. 1998
#1
Merritt,
B
2002
#4
Winston,
A.
2003
IPA for
transport
related
nausea
Other:
Intervention.
Evaluate the
effect of IPA
inhalation for
rescue
treatment of
POVN in adult
same day
surgery
patients who
underwent
general
anesthesia
Quasiexperimental
Compare the
efficacy of
inhaled
isopropyl
alcohol and IV
ondansetron
for the
treatment and
control of
PON in
groups of
women
undergoing
outpatient
gynecological
laparoscopic
procedures
Experimental
N=77
One
group
N=40
Two
groups
N=100
Two
groups
Patients
being
transported
within a
hospital
setting
Patients
inhale IPA
from a
wetted
upper lip
84% had relief
of symptoms,
15%did not
Level
5, B
Patients
undergoing
various
surgeries
3 sniffs
one inch
from the
nose.
Repeated
every five
minutes
for three
doses.
Intervention: 21
of 11 had relief
after first dose,
and 10 needed
at least one
intervention of
standard
medication.
Control group:
18 of 13 had
relief after the
first dose of
standard antiemetic. Five
had no relief.
Results not
significant
regarding
differences in
IPA being
superior to
standard
medications.
IPA group had
average cost of
9.75.
Control:17.08.
This is
significant.
Level
3B
Women,
laparoscopic
surgery
3 deep
breaths of
IPA, up to
3
treatments
41 of 100
experienced
nausea. 29 in
alcohol, 12 in
control. Time of
reduced nausea
of 6.3(alcohol)
vs 27.7(control).
Experimental
reported more
episodes of
PONV at home.
Level
2B
#6
Spencer,
K.
2004
#5
Cotton,
J.
2007
Review of
studies using
inhaled IPA
Literature
review
7 studies
reviewed
briefly
variable
Inhalation
of IPA
Varies. See
attached
summary
Level
5B
Validate the
results
reported from
Winston et al
and
determine
whether IPA
was just as
effective
through a
patient’s
entire
hospitalization
and in the
home setting.
Experimental
N=72
Women,
laparoscopic
surgery
3 deeps
breaths
every five
minutes,
up to 3
treatments
Level
2B
#2
Teran, L.
2007
To compare
IPA to IV
Granisetron in
Postoperative
nausea and
vomiting/
Quasiexperimental
Women,
Laparoscopic
surgery
3 deep
breaths of
IPA
Control group
reported 33.88
min to achieve
50% reduction
in nausea.
Experimental:15
min. Second
treatments:
control=26.25
min.
experimental=
15min. 13 of the
control group
needed rescue
treatment while
10 in the
experimental
needed rescue.
21 reported
nausea at
home, one
subject in
experimental
group used the
rescue
treatment while
5 in the control
needed it.
IPA group
reported more
episodes of
PONV in 6 to 24
hour
postsurgical
timeframe. No
significant
values between
groups
regarding
number of
PONV
episodes.
Two
groups
N=57
Three
groups
Level
3B