By the Numbers ACGT’s Top Researchers and Physicians Discuss the Success of Gene and Cell Therapy Co-founder and President Barbara Netter thanks donors for supporting ground-breaking and life-saving research New York, NY and Stamford, CT – (October 16, 2013) – More than 100 prominent donors, scientists, biotech representatives, and physicians attended Alliance for Cancer Gene Therapy’s “Achieving Cancer Remission with Cell and Gene Therapies” Tuesday night at the Harvard Club of New York City, 35 W. 44th Street. The evening highlighted recent tremendous strides made in combating cancer with cell and gene therapy treatments, and served as appreciation for donors who have committed time and funds to furthering research and clinical trials across the nation. “Our donors have allowed top scientific minds to explore this new and promising avenue of cancer treatment, and their philanthropy is directly linked to the lives saved so far,” said Barbara Netter, who co-founded Stamford-based ACGT in 2001 alongside her husband, Edward. Mrs. Netter stressed that much additional research needs to be funded in order to achieve the goal of the fully successful treatment of all types of cancer. To further that goal, Mrs. Netter has assumed the mantle of President of ACGT to chart a strategic course for the organization’s continued success. Guests were treated to an elegant reception at the Harvard Club, followed by a salutation from host Dr. Savio Woo. Dr. Woo – Chairman of ACGT’s Scientific Advisory Council and Professor of Hematology and Oncology at the Tisch Cancer Institute at Mount Sinai School of Medicine in New York City – was instrumental in ACGT’s founding over a decade ago. Also in attendance was Connie Burnett-West, a cancer survivor who overcame a critical case lung cancer with gene and cell therapy treatment. “Surgery and radiation weren’t options, and I was told I had limited hope for recovery,” Burnett-West said. “But after a sixth-month course of gene therapy, I’ve been in remission for over 10 years. I could not have imagined a treatment so easy and effective.” The evening’s capstone was a presentation from three of ACGT’s esteemed and award winning Research Fellows. Carl H. June (M.D., University of Pennsylvania), Laurence Cooper (M.D., Ph.D., MD Anderson Cancer Center) and Michel Sadelain (M.D., Ph.D., Memorial SloanKettering Cancer Center) spoke of the breakthroughs and growing momentum that gene and cell therapy has achieved with the support of ACGT. 23,200,000: The number of dollars awarded for ACGT endeavors. Of that, $11.3 million has gone toward discovery and research, and $11.9 million has gone toward translation into treatments. 100: The percent of donations that go directly toward research endeavors. Funding for administrative and fundraising costs is provided separately. 17: The number of funded research projects that have been approved for human clinical trials; 11 trials have started. These trials provide scientists and patients with the opportunity to put research into practice – and save lives. 3: The number of ACGT awardwinning doctors and research fellows presenting on this evening’s panel. Carl H. June M.D. with the University of Pennsylvania, Laurence Cooper M.D., Ph.D. with the MD Anderson Cancer Center, and Michel Sadelain M.D., Ph.D. with the Memorial Sloan-Kettering Cancer Center, will discuss recent breakthroughs and advances in the field of cell and gene therapies. 1: the number of charitable organizations in the nation dedicated exclusively to cell and gene-based therapies for cancer. “ACGT has the potential to provide less expensive and less harrowing cancer treatment – and, ultimately, a cure,” Dr. Carl June said. “And all of ACGT’s life-saving work was funded through philanthropy.” Moving forward, Barbara Netter noted that ACGT will continue its outstanding commitment to treating all forms of cancer. Exclusive interviews with Research Fellows are available on ACGT’s YouTube channel. For interview opportunities with Research Fellows and/or survivors, please contact Kat McKee at kat@cocommunications.com, or (914) 666-0066. For additional information on the Research Fellows and Dr. Woo, see the final page of this release. ACGT is located at 96 Cummings Point Road, Stamford, CT 06902. The foundation can be reached at (203) 358-8000 or by visiting www.acgtfoundation.com About Alliance for Cancer Gene Therapy (ACGT) Established in 2001, ACGT (www.acgtfoundation.org) is the nation’s only not-for-profit exclusively dedicated to cancer cell and gene therapy treatments for all types of cancer. One-hundred percent of contributions go directly to research. ACGT, which provides grants t o leading scientists in the U.S. and Canada, has funded 42 grants since its founding in 2001 by Barbara Netter and her late husband, Edward, to conduct and accelerate critically needed innovative research for all types of cancer. ACGT’s Scientific Advisory Council is comprised of 16 of the nation’s most pre-eminent physicians and researchers in cell and gene therapy, who thoroughly review all grants. Since its inception ACGT has awarded 27 grants to Young Investigators and 15 grants to Clinical Investigators, totaling $24.2 million in funding. Barbara Netter, as President, together with other members of the Board of Directors, are fully committed to ACGT’s continued support of this critically needed innovative research. ### Press Contact: Kat McKee / Kevin Zawacki Co-Communications 914-666-0066 kat@cocommunications.com / kzawacki@cocommunications.com Photo credit: Elaine Ubiña / www.fairfieldcountylook.com Alliance for Cell Gene Therapy Foundation (ACGT) hosted a panel event, “Achieving Cancer Remission with Cell and Gene Therapies,” at the Harvard Club in Manhattan on Tuesday, October 15, 2013. Pictured (L to R): Charles Hallac, (Scarsdale, NY); Barbara Netter, President & Founder, ACGT Foundation (Stamford, CT); Jeffrey Keil, Chairman of the Executive Committee, ACGT Foundation (New York, NY). Photo credit: Elaine Ubiña / www.fairfieldcountylook.com Alliance for Cell Gene Therapy Foundation (ACGT) hosted a panel event, “Achieving Cancer Remission with Cell and Gene Therapies,” at the Harvard Club in Manhattan on Tuesday, October 15, 2013. Pictured (L to R): Laurence Cooper, MD, PhD, of MD Anderson Center (Houston, Texas); Margaret C. Cianci, MBA, Executive Director (Stamford, CT): Savio L. C. Woo, PhD, of Mt. Sinai School of Medicine, and Chair, ACGT Scientific Advisory Council (New York, NY); Barbara Netter, President & Founder, ACGT Foundation (Stamford, CT); Carl H. June, MD, of the University of Pennsylvania (Philadelphia, PA): Michel Sadelain, MD, PhD, of Memorial Sloan-Kettering Cancer Center (New York, NY). Panelists Savio L.C. Woo, PhD – Panel Host Savio L.C. Woo, PhD, Founding Chair of ACGT Scientific Advisory Council. Chairman, ACGT Scientific Advisory Council Professor of Hematology and Oncology Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY Dr. Woo is an expert in molecular human genetics, and his pioneering work on gene therapy for genetic disorders and cancer is internationally recognized. He served as a regular member on the Cellular, Tissue and Gene Therapies Advisory Committee of the US Food and Drug Administration, and is a Past President of the American Society for Gene and Cell Therapy. Laurence Cooper, MD, PhD – Panelist, Research Fellow Laurence Cooper, MD, PhD, ACGT Research Fellow, Section Chief, Cell Therapy Children’s Cancer Hospital, Division of Pediatrics, Department of Immunology University of Texas MD Anderson Cancer Center, Houston, TX and a member of the Board of the American Society of Gene and Cell Therapy, is senior investigator on a type of immunotherapy that uses a new approach to gene therapy. He is chief of pediatric bone marrow transplantation and working to improve the therapeutic potential of this procedure by infusing genetically modified T cells reprogrammed to target malignancies. He has undertaken clinical trials in humans and in companion dogs to help demonstrate the potential of T cells to eradicate cancer. Carl H. June, MD - Panelist Carl H. June, MD, ACGT Research Fellow, Richard W. Vague Professor in Immunotherapy Department of Pathology and Laboratory Medicine Director Translational Research Program Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA. Dr. June and his team are making great strides in the treatment of advanced CLL (chronic lymphocytic leukemia). The groundbreaking clinical trial, initially funded by ACGT, uses genetically modified versions of the patient’s own T cells, and has shown remission for more than a year in a group of patients, many of whom are in complete remission. The treatment, which received international recognition, will next be tested on patients with ovarian and pancreatic cancer. Michel Sadelain, M.D., PhD. - Panelist Michel Sadelain, MD, PhD, ACGT Research Fellow, Director, Center for Cell Engineering Professor, Molecular Pharmacology & Chemistry Program Professor, Departments of Medicine and Pediatrics Memorial Sloan-Kettering Cancer Center, New York, NY and Vice President of the American Society of Gene and Cell Therapy, led the groundbreaking immunotherapy clinical trial for acute lymphoblastic leukemia (ALL), a rapidly progressing form of blood cancer. All five of the patients with relapsed B cell ALL who have received the new therapy – known as targeted immunotherapy – have gone into complete, molecular remission, with no detectable cancer cells. His lab has pioneered the design of multiple chimeric antigen receptors (CARs) that are now entering the clinic.