Genetics - jinr :: laboratory of radiation biology

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GENETICS
2 June
Plenary presentations:
9.30-11.00
Co-Chairmen: S.G. Inge-Vechtomov, M. Lynch
S.G. Inge-Vechtomov (St. Petersburg St. Un.; St. Petersburg Branch of Vavilov Inst. of
General Genetics, RAS, St. Petersburg, Russia) (30 min)
Template principle in biology
M. Lynch (Dept. of Biology, Indiana Un. Bloomington, Indiana USA) (30 min)
Evolution of the mutation rate
A.A. Rubel et al. (St. Petersburg St. Un., St. Petersburg, Russia; Georgia Inst. Tech.,
Atlanta, Georgia, USA) (30 min)
Protein assembly disorders and protein-based inheritance
11.20-13.00
Co-Chairmen: I.A. Tikhonovich, M.S. Gelfand
I. Kulakovsky (Engelhardt Institute of Molecular Biology; Vavilov Institute of General
Genetics, Moscow, Russia) (30 min)
Is there a nucleotide-level genetic code for gene expression control?
Yu. Pavlov (Eppley Inst. for Research in Cancer, Un. of Nebraska Med. Center, USA)
(30 min)
Mechanisms of global and region-specific control of mutagenesis
N.A. Kolchanov (Institute of Cytology and Genetics SB RAS, Novosibirk, Russia) (30 min)
Evolution of regulatory genetics systems
2 JUNE
Oral presentations: Mechanisms of genetic processes
15.00-17.00
Co-Chairmen: Yu. Pavlov, I. Kulakovsky
N.A. Koltovaya (Joint Inst. for Nuclear Research, Dubna, Russia) (20 min)
Genome stability: genetic and epigenetic factors
Lada A.G. et al. (St. Petersburg State Un., St. Petersburg, Russia; Eppley Inst. for Research
in Cancer and Allied Diseases, Un. of Nebraska Medical Center, Omaha, Nebraska, USA)
(20 min)
Transcription determines the landscape and clustering of mutations induced in diploid
yeast by aid/apobec deaminases
Nizhnikov A. A., Antonets K.S. (St. Petersburg St. Un.; St. Petersburg Branch of Vavilov
Inst. of General Genetics, RAS. St. Petersburg, Russia) (20 min)
Screenings for novel amyloid-forming proteins in bacteria Escherichia coli
Aksenova A.Y. et al. (Department of Biology, Tufts Un., Medford, MA, USA; St.
Petersburg St. Un., St. Petersburg, Russia) (20 min)
Instability of interstitial telomeric sequences
17.20 -18.00
N. Koltovaya, A.A. Nizhnikov
Khlestkina E.K. Shoeva O. (Inst. of Cytology and Genetics SB RAS, Novosibirsk, Russia)
(20 min)
Organization and evolution of the duplicated flavonoid biosynthesis genes in triticeae
Proshkina E.N. et al. (Inst. of Biology of Komi Science Center of Ural Branch of RAS;
Syktyvkar St. Un., Syktyvkar; Moscow Inst. of Physics and Technology, Dolgoprudny;
Engelhardt Inst. of Molecular Biology, RAS, Moscow, Russia) (20 min)
The influence of the activity of DNA damage recognition and repair genes on the lifespan
of Drosophila melanogaster
4 JUNE
Oral presentations: Cancer genetics & Cancer therapy
15.00-17.00
Co-Chairmen: M. Rosemann, L. Bullinger
Rosemann M. (Helmholtz Center Munich, German Research Center for Environmental
Health
Inst. of Radiat. Biol., Munich, Germany) (30 min)
Stem cells and radiation effects
Sander S., van Chu T., Rajewsky K. (Immune Regulation and Cancer, Max-DelbrückCenter for Molecular Medicine in the Helmholtz Association, Berlin, Germany) (30 min)
From cancer genetics to targeted therapies - modeling human lymphoma pathogenesis in
mice
Bullinger L. (Department of Internal Medicine III, University of Ulm, Germany) (30 min)
Acute myeloid leukemia leads the way in molecular cancer genetics: precision medicine at
reach?
Ayinde F., Zyuzikov N. (University of the West Indies, St Augustine, Trinidad and Tobago)
Tumour treating fields - new type of cancer therapy (30 min)
17.20-18.00
Co-Chairmen: N.A. Zyuzikov, Sander S.
Evstratova E.S., et al. (A. Tsyb Scientific Research Centre of Radiology of the Hertsen
Federal Medical Research Centre of the Ministry of Health of the RF, Obninsk, Russia) (20
min)
Radiobiological basis of densely ionizing radiation application in nuclear medicine
2 JUNE
Poster session: Mechanisms of genetic processes
13.00-14.00
Akbarova G. (Khazar University, Baku, Azerbaijan)
The correction of the UV-induced mutagenesis by extract from kiwi fruit
Aliev K., Partoev K., Naimov A.(Inst. of Botany, Plant Physiology and Genetic of Academy
Science of the Republic of Tajikistan)
Combining of recombination methods with biotechnology in potato breeding in Tajikistan
Andreychuk Y.V. et al (St.Petersburg St. Un.; St.Petersburg Branch of Vavilov Institute of
General Genetics, RAS, St. Petersburg, Russia)
Prion [PSI+] has an impact in the control of genome stability in yeast Saccharomyces
cerevisiae
Antonets K.S., Drozdova P.B., Nizhnikov A.A. (St.Petersburg St. Un.; St.Petersburg Branch
of Vavilov Institute of General Genetics, RAS, St. Petersburg, Russia)
Amyloidogenic properties of archeal proteins depend on environmental conditions
Antosyuk O.N., Marvin N.A., Shihova S.V. (Ural Federal Un. named after the first President
of Russia B.N. Yeltsin, Yekaterinburg, Russia)
The influence of the long direct selection on a mutagenesis of hetezygotes vg+vg.
Dobrovolskaya E., et al. (Inst. of Biology of Komi Science Center of Ural Branch of RAS,
Syktyvkar; Syktyvkar St. Un., Syktyvkar; Moscow Inst. of Physics and Technology,
Russia)
Caloric restriction influences lifespan of Drosophila melanogaster individuals whose
genes controlling circadian rhythms are overexpressed in peripheral tissues
Golyasnaya N.V, Tsvetkova N.A (Inst. of Ecology and Genetics of Microorganisms, Ural
Branch of RAS, Perm, Russia)
Nucleotide sequence context and mutability of Escherichia coli genes
Kliver S., Lada A., Pavlov Y. (St. Petersburg St. Un., Russia; Eppley Inst. for Research in
Cancer and Allied Diseases, Un. of Nebraska Medical Center, Omaha, Nebraska, USA)
Genome-wide identification of mutation clustering using a new hierarchical method
Partoev K., et al (Inst. of Botany, Plant Physiology and Genetics of the Academy of
Sciences of the Republic of Tajikistan; Centre of Innovative Development of Sciences and
New Technologies of the Academy Science of the Republic of Tajikistan)
Crossing and grafting of American artichoke (Helianthus tuberosus l.) with sunflower
(Helianthus annuus l.) in the conditions of Tajikistan
Proshkina E.N. et al. (Inst. of Biology of Komi Science Center of Ural Branch of RAS;
Syktyvkar St. Un., Syktyvkar; Moscow Inst. of Physics and Technology, Dolgoprudny;
Engelhardt Inst. of Molecular Biology, RAS, Moscow, Russia) (20 min)
The influence of the activity of DNA damage recognition and repair genes on the lifespan
of Drosophila melanogaster
Shiriaeva A.A., et al (St.Petersburg St. Un.; St.Petersburg Branch of Vavilov Institute of
General Genetics, RAS, St. Petersburg, Russia)
The origin of sterile cytoductants obtained in the alpha-test
Stepchenkova E.I., Tarakhovskaya E.R., Pavlov Y.I. (St. Petersburg St. Un.,; St. Petersburg
Branch of Vavilov Institute of General Genetics, RAS, St. Petersburg, Russia; Un. of
Nebraska Medical Center, USA)
Fe-S clusters associated with the C-terminus of the DNA polymerase delta are essential for
DNA polymerases switch and in this way control spontaneous and induced mutagenesis
Tsvetkova N.A., Golyasnaya N.V. (Institute of Ecology and Genetics of Microorganisms,
Ural Branch of RAS, Perm, Russia)
Antibiotic resistance of strains Pseudomonas aeruginosa ATCC 27853 and small-colony
variants
Yakovlev A, et al (Russian Inst. of Genetics and Breeding FANO, St-Petersburg, Russia)
The use of DNA technology to monitor genetic heterogeneity in broiler lines
Zhuk A.,et al (St.Petersburg St. Un.; St.Petersburg Branch of Vavilov Institute of General
Genetics, RAS, St. Petersburg, Russia)
Molecular nature of primary DNA lesions detected in the alpha-test
2 JUNE
Poster session: Cancer genetics & Cancer therapy
13.00-14.00
Ameliyanovich M. D.( Inst. of Genetics and Cytology NAS Belarus, Minsk, Belarus)
Association between metabolic syndrome and gene polymorphism in Belarusian
population
Djansugurova L., et al (Inst. of General Genetics and Cytology, SC MES RK, Almaty,
Kazakhstan)
Analysis of critical regions of candidate genes for familial and sporadic colorectal
cancer cases
Makarenko S.A., Zamulaeva I.A (A. Tsyb Scientific Research Centre of Radiology of the
Hertsen Federal Medical Research Centre of the Ministry of Health of the RF, Obninsk,
Russia)
Realization cytogenetic damage in irradiated human cells for additional action of comutagen Effects of photodynamic therapy on cancer stem cells (CSCs) in vitro
Pylypchuk E.P, Domina E.A (R.E. Kavetsky Experimental Pathology, Oncology and
Radiobiology Inst., NAS of Ukraine, Kiev, Ukraine)
Realization of cytogenetic damage in irradiated human cells for additional action of comutagen
Pronyushkina K.A., et al (A.Tsyb Medical Radiological Research Center, P. Hertsen
Federal Medical Research Center Branch, Ministry of Health of the RF, Obninsk; Inst. of
Carcinogenesis, Blokhin Cancer Research Center, RAMS, Moscow; Engelhardt Inst. of
Molecular Biology, RAS, Moscow, Russia)
Radiomodifying effect of dimeric bisbenzimidazoles on cancer stem cells (CSCs) of
breast adenicarcinoma line MCF-7
Vorobtzova I., Semenov A., et al. (Federal State Institution Russian Research Center
for Radiology and Surgical Technologies, St. Petersburg, Russia)
Fish analysis of exfoliated urine cells for detection of bladder cancer
Vyazovskaya N.S., Rusinova G.G., Azizova T.V. (Southern Urals Biophysics Institute
Ozyorsk, Russia)
Role of CYP1A1 polymorphism of cytochrome P450 family genes in susceptibility to
lung cancer in Mayak PA workers
Zimatkina T.I., Goncov A.I. (Grodno State Medical University, Grodno, Belarus)
Ecologo-hygienic approaches to restriction of the medical irradiation for prevention of
the development of the malignant tumors
4 JUNE
Discussion: Variability laws
17.20- 17.40
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