PHC 6003 EPIDEMIOLOGY AND PREVENTION OF CHRONIC DISEASES Fall SEMESTER 2012 Section 1635 Instructor Todd Manini, Ph.D. Email: tmanini@ufl.edu Phone: 273-5914 Hours: Tuesday 9:00-10:00 AM or by appointment. Office: Building 220 (Aging Rehabilitation and Research Center). See map Teaching assistant Xingdi Hu Email: qmshjwhx@phhp.ufl.edu Hours: Thursday 3:15-4:15 or by appointment. Office: To be announced Class time and location Wednesday 1:55-4:55 PM Room 1102, HPNP Required textbook Title: Epidemiology of Chronic Disease: Global Perspectives Author: Randal E. Harris Publisher: Jones & Bartlett Learning ISBN: 1449653286 Materials will be assigned and provided on the Sakai for downloading. Prerequisite courses: PHC 6001 and PHC 6052 / PHC 6050 Course description This course extends the concepts and methods of epidemiology from PHC 6001 (Principles of Epidemiology) to specific chronic diseases that include: cancer, musculoskeletal, cardiovascular and metabolic origins. It is intended to be a survey of the major chronic diseases with emphasis on recent epidemiology research and findings. Research design, case definition and disease etiology are emphasized throughout the course. The student will develop competency in identifying and understanding the historical context of chronic disease epidemiology, epidemiological terminology of specific chronic diseases and methodological concepts. The student will be expected to communicate current epidemiological constructs in chronic disease using both written and oral forms. The goal of this course is to provide a foundation in epidemiological methods to study a variety of chronic diseases and communicate findings to the field of public health. Course Objectives 1. Interpret study designs and methods used in epidemiologic research to survey risk factors for chronic disease. 2. Identify methodological principles to study chronic disease. 3. Develop a basic understanding of disease etiology and patho-physiology sufficient to use in epidemiological settings. 1 4. 5. 6. 7. Critically apprise published research studies for their strengths and weaknesses. Communicate epidemiology of chronic disease in written and oral forms. Identify etiologic factors in causation of chronic diseases. Evaluate epidemiological methods used as preventative strategies (surveillance and intervention). Additional specific objectives might be presented throughout the course. Evaluation Weekly assignment – Students will complete a weekly assignment. Typically, this assignment will be a one-page page paper (signal spaced, 1 inch margins). The paper will focus on developing a design to study a specific chronic disease— one that was discussed in the previous lecture. Attendance in the class is necessary to have knowledge of the weekly assignment. Presentations - Students will present one assigned research article. The presenting student is expected to make a formal presentation of the paper, i.e., PowerPoint presentation. The presentation should include some information about the author(s) or the database/clinical trial or cohort that might not be included in the paper itself. Following the presentation, the student will be expected to answer questions from the instructor and other class members. The presentation and question and answer period should last 13-15 minutes. The presentations will be timed and points will be deducted if the time is either too short or too long. The presenter is expected to be the "expert" on the topic, which may require reviewing other papers for background. Each student will provide a peer evaluation that will count as part of their presentation grade. Mid-term Exam – The mid-term exam will cover lecture material and reading assignments that are presented prior to the mid-term examination. The exam will include a combination of multiple choice and essay questions. Final exam – The final exam will cover lecture material and reading assignments that are presented following the mid-term examination. The exam will include a combination of multiple choice and essay questions. Class Attendance - Class attendance is mandatory. Excused absences follow the criteria of the UFL Graduate Catalogue (e.g., illness, serious family emergency, military obligations, religious holidays), and should be communicated to the instructor prior to the missed class day when possible. UFL rules require attendance during the first two course sessions, and students also must attend all course sessions of student presentations for this class. Missing more than three scheduled sessions without qualified excuse will result in a failure. Regardless of attendance, students are responsible for all material presented in class and meeting the scheduled due dates for class assignments. Evaluation Weekly assignment / attendance Presentation & peer evaluation Mid-term exam Final exam Percent of final grade 30% 20% 25% 25% Policy on Make-Up Work: No make-ups will be permitted for in class assignments. The assignment will not be counted for those students who miss class due to a qualified absence. An assignment may be completed prior to the due date in absences that have been pre-approved by the instructor. Students are allowed to make up presentations ONLY as the result of illness or other unanticipated circumstances warranting a medical excuse and resulting in the student missing a presentation, 2 consistent with College policy. Documentation from a health care provider is required. Work missed for any other reason will receive a grade of zero. Grading Letter A grade Grade 4.0 points A- B+ B 3.67 3.33 3.0 B- C+ C 2.67 2.33 2.0 C- D+ D 1.67 1.33 1.0 D- E 0.67 0 WF I NG 0 0 0 SU 0 Non-Punitive Grades and Symbols – Zero Grade Points; Not Counted in GPA W = Withdrew U = Unsatisfactory H = Deferred grade assigned only in approved sequential courses or correspondence study N* = No grade reported I* = Incomplete Failing Grades – Zero Grade Points; Counted in GPA E = Failure WF = Withdrew failing NG = No grade reported I = Incomplete Back to Top I*, N* and I, NG Grades I* or N* grades recorded on the student record indicate the non-punitive initial-term receipt of an I or NG. A grade of I* or N* is not considered a failing grade for the term in which it is received, and it is not computed in the grade point average. However, if the I* or N* has not been changed by the end of the next term for which the student is enrolled and receives grades, it will be counted as a failing grade and used in computation of the grade point average. For purposes of determining grade point average after the initial receipt of an I* or N* grade, the three summer terms are considered collectively as a single term. I* and N* grades are not assigned to graduating students; they receive failing grades of I or NG. An incomplete grade may be assigned at the discretion of the instructor as an interim grade for a course in which the student has completed a major portion of the course with a passing grade, been unable to complete course requirements before the end of the term because of extenuating circumstances, and obtained agreement from the instructor and arranged for resolution of the incomplete grade. Instructors are not required to assign incomplete grades. If make-up work requires classroom or laboratory attendance in a subsequent term, the students should not register for the course again. Instead, the student must audit the course and pay course fees. If the make-up work does not require classroom or laboratory attendance, the instructor and student should decide on an appropriate plan and deadline for completing the course. When the course is completed, the instructor will initiate the change of grade. These procedures cannot be used to repeat a course for a different grade. An I* grade will not be assigned to a student who never attended class; instead, instructors will assign a failing grade. 3 Accommodations for Students with Disabilities If you require classroom accommodation because of a disability, you must first register with the Dean of Students Office (http://www.dso.ufl.edu/). The Dean of Students Office will provide documentation to you, which you then give to the instructor when requesting accommodation. The College is committed to providing reasonable accommodations to assist students in their coursework. Counseling and Student Health Students may occasionally have personal issues that arise in the course of pursuing higher education or that may interfere with their academic performance. If you find yourself facing problems affecting your coursework, you are encouraged to talk with an instructor and to seek confidential assistance at the University of Florida Counseling Center, 352-392-1575, or Student Mental Health Services, 352392-1171. Visit their web sites for more information: http://www.counsel.ufl.edu/ or http://www.health.ufl.edu/shcc/smhs/index.htm#urgent The Student Health Care Center at Shands is a satellite clinic of the main Student Health Care Center located on Fletcher Drive on campus. Student Health at Shands offers a variety of clinical services, including primary care, women's health care, immunizations, mental health care, and pharmacy services. The clinic is located on the second floor of the Dental Tower in the Health Science Center. For more information, contact the clinic at 392-0627 or check out the web site at: www.health.ufl.edu/shcc Crisis intervention is always available 24/7 from: Alachua County Crisis Center: (352) 264-6789. Do not wait until you reach a crisis to come in and talk with us. UF counseling services have helped many students through stressful situations impacting their academic performance. You are not alone so do not be afraid to ask for assistance. Classroom etiquette Please come to class on time and be prepared to stay until the time scheduled as the end of class. We think your investment in the degree is worth my maximizing your in-class experience, and we usually provide materials that extend the full, scheduled class times. Pagers and cell phones should not be used in class. The use of cell phones, text messaging, and pagers is one of the most common complaints I have from students in recent years. Please turn them off. Or, if you expect urgent calls, set them to “vibrate.” 4 # Date Topic 1 8/22/12 Course overview 2 8/29/12 Introduction and review 3 9/5/12 Epidemiology of Cardiovascular disease I 4 9/12/12* Epidemiology of Cardiovascular disease II 5 9/19/12 Epidemiology of Diabetes I 6 9/26/12** Epidemiology of Diabetes II 7 10/3/12 Epidemiology of Obesity & The metabolic syndrome 8 10/10/12* Epidemiology of physical activity & sedentary behavior & Jeopardy mid-term exam review 9 10/17/12 Mid-term – 1.5 hours 10 10/24/12*** Epidemiology of Cancer I 11 10/31/12^ Epidemiology of Cancer II 12 11/7/12 Epidemiology of Cancer III 13 11/14/12 Epidemiology of Musculoskeletal disorders I 14 11/21/12 Epidemiology of Musculoskeletal disorders I 15 11/28/12 Epidemiology of Aging, physical disability & dementia I 16 12/5/12 Epidemiology of Aging, physical disability & dementia II & Jeopardy final exam review Final exam: Wednesday, December 12th, 1:55 to 4:55 * TA oversight at end of class * TA oversight at end of class *** Guest lecturer ^ TA lecture 5 # 1 2 3 Date 8/22/12 8/29/12 9/5/12 Topic Course overview Introduction and review Epidemiology of Cardiovascular disease I 4 9/12/12 Epidemiology of Cardiovascular disease II 5 9/19/12 Epidemiology of Diabetes I 6 9/26/12 Epidemiology of Diabetes II 7 10/3/12 Epidemiology of Obesity & The metabolic syndrome 8 10/10/12 11 10/31/12 Epidemiology of physical activity & sedentary behavior & Jeopardy mid-term exam review Mid-term – 1.5 hours Epidemiology of Cancer I: Pathophysiology of cancer. Surveillance Epidemiology & End Results (SEER) Epidemiology of Cancer II: Lung & Breast 12 11/7/12 Epidemiology of Cancer III: Cervical & Prostate 13 11/14/12 Epidemiology of Musculoskeletal disorders I 14 11/21/12 Epidemiology of Musculoskeletal disorders I 15 11/28/12 16 12/5/12 Epidemiology of Aging, physical disability & dementia I Epidemiology of Aging, physical disability & dementia II None & Jeopardy final exam review 9 10/17/12 10 10/24/12 Presenter: Article None None Cortes: Ridker et al. 17299196 Patwary: Sacks et al. 11136953 Tiemeier: Voight et al. 22607825 Jones: Bibbins-domingo et al. 17213400 Szary: Accord Lipid trial Scheidell: Van Dam et al. 16443894 Cohen: School-Health Study group 20581420 McMurray: DPP trial 11832527 Dekevich: Flegal et al. (cause-specific deaths) 17986696 Ochonma: Sjostrom et al. 15761173 None None Boyce: Oken et al. (22031728) Blanc: Luo et al. (21878422) Johnston: Chlebowski et al. (12824205) Finlay: LaCroix et al. (21467283) Phillips: Lehtinen et al. (22075171) Bliss: Andriole et al. (22228146) Kan: Eckstein et al (22730370) Haguewood: Clegg et al. (16495392) Hu: Kern et al (15684205) Tremblay: Cauley et al. (15870413) Sura: Basaria et al. (20592293) 6 Presenter: PRESENTATION STYLE Overall effectiveness of delivery (Well-practiced, engaging, etc) Presenter spoke clearly with correct speed, cadence, and volume Presentation fit within time Allotted (13-15 min) Professionalism of presentation and Presenter’s demeanor Comments AUDIO/VISUAL Appropriate use of slides (number of slides, time on each slide,etc.) Quality of text slides (legible, enhance verbal portion, etc) Quality of graphs, tables, images Comments CONTENT Presentation was well organized and easy to follow Clarity and progression of ideas Appropriate integration of scientific data/background If applicable: Hypotheses were clearly stated Study design and setting were clearly stated and accurate Depth of explanation / educational content was appropriate Explanation of statistical design was appropriate Overall educational value Comments PRESENTATION EVALUATION FORM Date: Unacceptable Average Very Good Excellent 1 Needs Work 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 Unacceptable Average Very Good Excellent 1 Needs Work 2 3 4 5 1 2 3 4 5 1 2 3 4 5 Unacceptable Average Very Good Excellent 1 Needs Work 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 1 2 3 4 5 7