____________________________ Modern Genetics Review ____________________________ ____Modern Genetics Review____ Multiple Choice Identify the choice that best completes the statement or answers the question. ____ ____ ____ ____ ____ ____ ____ ____ ____ ____________________________ _ 1. Which of these traits is controlled by a gene with multiple alleles? a. straight hairline b. smile dimples c. widow’s peak d. blood type 2. Why does height in humans have such a wide variety of phenotypes? a. Height is controlled by at least four genes. b. The gene for height has only two alleles. c. Height is controlled by sex-linked genes. d. Height is controlled by a recessive allele. 3. What controls variations in skin color among humans? a. a person’s diet b. many genes c. multiple alleles of a single gene d. two alleles of a single gene 4. Which of these human traits is altered by variations in environment? a. hairline b. height c. smile dimples d. blood type 5. What is a pedigree? a. a chart that tracks which members of a family have a particular trait b. a geneticist who studies the inheritance of traits in humans c. a picture of all of the chromosomes in a cell d. an allele passed from parent to child on a sex chromosome 6. What would be the best way to predict the probability of a baby having cystic fibrosis? a. by studying the parents’ karyotypes b. by studying the family’s pedigree chart c. by exploring new methods of genetic engineering d. by determining whether the parents have codominant alleles 7. What is the purpose of the Human Genome Project? a. to identify the DNA sequence of every gene in the human genome b. to clone every gene on a single chromosome in human DNA c. to cure genetic diseases d. to inbreed the best genes on every chromosome in human DNA 8. Both parents of a child have type A blood. What might their child’s blood type be? a. Type A only b. Type A or type B c. Type A or type O d. Type A or type AB 9. Sex-linked genes are genes on a. the X chromosome only. b. the Y chromosome only. c. the X and Y chromosomes. d. all 23 pairs of chromosomes. ____ 10. Which form of selective breeding crosses parents with the same or similar sets of alleles? a. fertilization b. inbreeding c. hybridization d. cloning ____ 11. Hemophilia is caused by a(n) a. recessive allele on the X chromosome. b. extra chromosome. c. dominant allele. d. codominant allele. ____ 12. Many characteristics are affected by interactions between genes and a. chromosomes. b. the environment. c. alleles. d. carriers. ____ 13. Adults with Down syndrome can often find work because they have received a. folic acid. b. physical therapy. c. education and job training. d. genetic counseling. 14. What do the squares represent on the pedigree? _______________________________________________________ _____________________________________________________________________________________________ 15. Which pairs of individuals in the pedigree have children? _______________________________________________ 16. Which individuals neither have the trait nor are carriers? ________________________________________________ 17. Could the trait that is traced by this pedigree be sex-linked? Explain why or why not. _________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ Completion Complete each statement. 18. Except for ______________________________, all people have different DNA. 19. The three alleles on the single gene that controls blood type are said to be ___________________________. 20. When many genes control a trait, the trait will show a large number of ______________________________. 21. A carrier is a person who has one ____________________________________ allele for a trait. 22. A(n) ___________________________________ is used to track the occurrence of a trait in a family. 23. People who have the genetic disorder called ____________________________________ suffer from abnormally low levels of oxygen in the blood. 24. A person who has the genetic disorder called __________________________________ bleeds easily. 25. ____________________________________________ is caused by the presence of an extra chromosome. 26. Breeders use a technique called ___________________________ to cross genetically different individuals. 27. A gene from one organism is inserted into the DNA of another organism in the process known as ___________________________________________________. 28. Scientists in the Human Genome Project are working to identify the _______________________________ of every human gene. 29. All of the DNA in one cell of an organism is called a(n) _______________________________________. 30. A selective breeding technique called _____________________________________ has been used to breed purebred racehorses. 31. A pattern produced from fragments of the DNA of a specific person is called a(n) ____________________________________________. 32. A karyotype can be used to determine the number of _____________________________ in a person’s cells. Create a Pedigree Draw a pedigree using the following information. Be sure to create an appropriate key. 33. Jane and Joe are the first generation in the pedigree. Jane is a carrier of sickle-cell disease. They have two boys, Scott and Ryan. Ryan is not a carrier and does not have any offspring. Scott is a carrier of sickle-cell disease and marries Heather who is also a carrier. They have four children. Sara and Jim are carriers of sickle-cell disease and Megan and George have sickle-cell disease. (Be sure to label the pedigree.) Essay Fully answer all of the following questions with detailed explanation. Minimum of four well developed complete sentences. 34. Human eyes come in a variety of colors ranging from light blue to very dark brown. Explain why eye color is not likely to be controlled by a single gene. ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ 35. Explain what causes cystic fibrosis and describe its effects on the body. What are some treatments for those with the disease? ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ 36. A plant breeder clones a plant with beautiful flowers. Define cloning and explain how the cloned offspring compare to the parent plant. ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ 37. Contrast hybridization and inbreeding. ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________ ______________________________________________________________________________________________