New Application: Medical Biochemical Genetics
Review Committee for Medical Genetics and Genomics
ACGME
515 North State Street, Suite 2000, Chicago, Illinois 60654  312.755.5000  www.acgme.org
SPONSORING INSTITUTION
Will the sponsoring institution also sponsor ACGME-accredited residencies in the following specialties?
[PR.I.A.1.]
a) Medical genetics ..................................................................................................... ☐ YES ☐ NO
b) Pediatrics ................................................................................................................ ☐ YES ☐ NO
c) Internal medicine ..................................................................................................... ☐ YES ☐ NO
Explain any NO responses.
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PROGRAM PERSONNEL AND RESOURCES
Program Director
Provide a list of the clinical conferences, seminars, journals clubs, rounds, and other didactic sessions
that will be provided. Comment on the planned levels of teaching staff participation and fellow
attendance at these sessions. Provide a list of topics and speakers as appropriate. [PR II.A.3.e).(3)]
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Other Program Personnel
1. Concisely summarize the technical, clerical, and other non-physician personnel who will provide
support for the administrative and educational conduct of the program. Is the support of the
program in this area satisfactory at all program sites? [PR II.C.]
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2. Working with Other Health Care Professionals
Summarize the opportunities fellows will have to work with genetic counselors, genetics residents,
psychologists, and other health care professionals who are involved in the provision of medical
biochemical genetics services. [PR II.C.1.; IV.A.2.d).(2)-(3), IV.A.2.f).(9)]
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Resources
1. Provide the data requested below, including the number of analyses and the analytic method, for
each biochemical genetics laboratory that will contribute significantly to the education of fellows.
Duplicate table as needed. [PR II.D.1.]
12-Month Period Covered by
Statistics
From: Click here to enter a
date.
Medical Biochemical Genetics
©2015 Accreditation Council for Graduate Medical Education (ACGME)
To: Click here to enter a date.
Updated 4/2015
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Name of Laboratory:
Address:
Name of Laboratory Director:
Test
Newborn Screening
Amino Acid Analysis
Organic Acid Analysis
Acylcarnitine profile
Mucopolysaccharide Screening
Enzyme analyses
1.
2.
3.
Other small molecule analyses
1.
2.
3.
Prenatal Diagnosis: Disorders
1.
2.
3.
List Other:
Number of Analyses
Analytic Method
2. Concisely describe the meeting rooms, classrooms, office space, research space, and facilities for
record storage and retrieval utilized by the program. [PR II.D.3.a)]
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3. Concisely describe the office and laboratory space provided for fellows for both patient care work
and participation in scholarly activities. [PR II.D.3.b)]
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4. Provide the patient visit or consult numbers below for each site/clinic based upon the prior
academic or calendar year. Note: A single patient may be counted only up to 3 times, irrespective of
the number of visits/encounters; for inpatients, each admission is a single encounter (i.e., each daily
visit during a single admission is NOT counted). (Copy table as necessary.) [PR II.D.2.; II.D.4.]
12-Month Period Covered by
Statistics
Site/Clinic Name
Types of New Patients
Hyperammonemic crisis
Metabolic or lactic
acidosis
Newborn screen
Total
From: Click here to enter a
date.
0-5
5-10
10-20
Medical Biochemical Genetics
©2015 Accreditation Council for Graduate Medical Education (ACGME)
To: Click here to enter a date.
20-30
> 30
Total
Updated 4/2015
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Site/Clinic Name
Types of Established
Patients
Fatty acid oxidation
disorders
Galactosemia
Glycogen storage
diseases
Lysosomal storage
disease
Mitochondrial/energy
metabolism disorders
Organic acidemias
PKU
Urea cycle disorders
Total
0-5
5-10
10-20
20-30
> 30
Total
EDUCATIONAL PROGRAM
Medical Knowledge
1. Describe how (including specific role), and in what settings, fellows learn about the acute
management of IEMs. [PR IV.A.2.b).(1).(d).(i)]
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2. Describe how (including specific role), and in what settings, fellows learn about the chronic
management of IEMs. [PR IV.A.2.b).(1).(d).(ii)
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3. Describe how (including specific role), and in what settings, fellows learn about enzyme
replacement therapies and organ transplant. [PR IV.A.2.b).(1).(d).(iii)
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4. Describe how (including specific role), and in what settings, fellows learn about newborn screening
programs and confirmatory testing. [PR IV.A.2.b).(1).(e)]
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Curriculum Organization and Resident Experiences
1. Will fellows have the opportunity to develop the abilities to diagnose IEM, counsel patients, and
manage the broad range of clinical problems that are encompassed by biochemical genetics?
[PR IV.A.3.b)] ............................................................................................................... ☐ YES ☐ NO
2. Describe the role of the fellow and settings for learning about care of adults with IEMs.
[PR IV.A.3.b)]
Medical Biochemical Genetics
©2015 Accreditation Council for Graduate Medical Education (ACGME)
Updated 4/2015
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3. Briefly describe how fellows will be provided with structured education, including formal coursework,
in the basic sciences and clinical areas pertinent to biochemical genetics, including population and
newborn screening, disorders of amino acid metabolism, disorders of fatty acid oxidation,
mitochondrial disorders, galactosemia, glycogen storage diseases, lysosomal storage diseases and
lipidoses, peroxisomal disorders and other IEM, acute management of IEM, enzyme replacement
therapy, long-term nutritional management, and molecular diagnosis. (An introductory medical
genetics course for clinical genetics specialists alone does not satisfy this requirement.)
[PR IV.A.3.c).(1)]
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4. Will fellows be provided with mentored clinical education in the practice of biochemical genetics in
both outpatient and inpatient settings? [PR IV.A.3.c).(2)] ............................................. ☐ YES ☐ NO
5. Will fellows be provided with advanced instruction in the interpretation of biochemical laboratory test
results? [PR IV.A.3.c).(3)] ............................................................................................ ☐ YES ☐ NO
6. Will fellows be provided with basic instruction in medical biochemical genetic laboratory testing?
[PR IV.A.3.c).(4)] .......................................................................................................... ☐ YES ☐ NO
7. What is the planned nature and extent of fellow experience during their assignments to the
biochemical laboratory? Describe planned fellow participation in the working conferences of these
laboratories and the ongoing discussions of laboratory data during other clinical conferences.
[PR IV.A.3.d)]
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8. Provide a list of the planned lectures and other didactic sessions which meet the requirement for a
course in biochemical genetics. (Such a course must be more advanced than the genetics course
given to medical students.) [PR IV.A.3.e)]
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Fellows’ Scholarly Activities
Summarize program research activity and list the staff member(s) who will provide support and
supervision of clinical or laboratory research activity by fellows and identify their particular area(s) of
expertise. [PR IV.B.1.]
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Medical Biochemical Genetics
©2015 Accreditation Council for Graduate Medical Education (ACGME)
Updated 4/2015
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