Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
Final Program of Metabolism Meets Virulence 2
6. April 2014, University Osnabrück, Palace
From 15:00
Registration
16:00-17:30
Biolog Workshop, Barry Bochner
18:00 Welcome by the speaker of SPP1316
Keynote Lecture, Chair: Michael Hensel
18:15 Andreas J. Bäumler, Davis, USA
How the host response feeds Salmonella
19:30 Reception and informal get together
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Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
7. April 2014, Steigenberger Hotel Remarque
Session 1: Adaptation to extracellular lifestyles 1, Chair: Sven Hammerschmidt
8:30
Richard Proctor, Madison, USA
Staphylococcus aureus SCV persisters: Multiple metabolic mechanisms
9:00
Christine Josenhans, Hannover, Germany
Energy sensing in pathogenic -proteobacteria: hub between metabolism and
virulence functions
9:30
Andre Kriegeskorte, Münster, Germany
Common metabolic features of Staphylococcus aureus small colony-variants
9:50
Jörg Willenborg, Hannover, Germany
Role of CcpA in the regulation of the metabolism and virulence of Streptococcus suis
10:10 Hasan Yesilkaya, Leicester, United Kingdom
Studies on pneumococcal esterases
10:30 Coffee break
Session 2: Global regulation of bacterial metabolism, Chair: Petra Dersch
11:00 Jay C. D. Hinton, Liverpool, United Kingdom
Lag is the forgotten growth phase: What happens during the earliest stage of growth
of a bacterial cell?
11:30 Jörg Stülke, Göttingen, Germany
c-di-AMP an emerging essential secondary messenger that links nutrient availability
to cell wall synthesis
12:00 Christoph Schön, Würzburg, Germany
Stringent response in ex vivo survival of Neisseria menigitidis
12:20 Markus Bischoff, Homburg, Germany
Influence of catabolite control proteins on infectivity of Staphylococcus aureus
12:40 Tanja Kern, Freising, Germany
Host-adapted N-Metabolism of Listeria monocytogenes
13:00 Lunch
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Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
Session 3: Metabolism of intracellular bacteria, Chair: Werner Goebel
14:00 John McKinney, Lausanne, Switzerland
Non-growing but metabolically active (NGMA) phenotypic variants
14:30 Michael Hensel, Osnabrück, Germany
A new view on the intracellular habitat of Salmonella enterica
14:50 Amanda Chidlaw, Norwich, United Kingdom
Adaptation of the intracellular metabolism of Salmonella Typhimurium to the host cell
environment
15:10 Johannes Rothhardt, Freising, Germany
Link between myo-inositol metabolism and virulence in Salmonella Typhimurium
15:30 Coffee Break
Session 3 continued
16:00 Hubert Hilbi, Zurich, Switzerland
Metabolism of glycerol, inositol and phytate by Legionella and implications for
virulence
16:20 Klaus Heuner, Berlin, Germany
The metabolism of Legionella pneumophila investigated by isotopologue profiling
16:40 Catherine Vilcheze, New York, USA
Phosphorylation of a -keto-acyl ACP synthase regulates cell wall composition, acidfast staining and virulence in Mycobacterium tuberculosis
17:00 Poster session
19:30 Dinner at Rampendahl
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Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
8. April 2014, Steigenberger Hotel Remarque
Session 4: Host microbiota and bacterial pathogens, Chair: Jürgen Heesemann
8:30
Tyrrell Conway, Oklahoma, USA
The restaurant hypothesis of intestinal colonization
9:00
Dirk Bumann, Basel, Switzerland
Salmonella metabolism heterogeneity in infected host tissues
9:30
Sebastian Winter, Dallas, Tx, USA
Host-derived nitrate boosts growth of E. coli in the inflamed gut
9:50
Dirk Hofreuter , Hannover, Germany
Exploring the metabolic interface between the gastrointestinal pathogen
Campylobacter, its host and the microbiota
10:10 Ivan Berg, Freiburg, Germany
Bacterial itaconate degradation promotes pathogenicity
10:30 Coffee break
Session 5: Adaptation to extracellular lifestyles 2, Chair: Gottfried Wilharm
11:00 Andreas Peschel, Tübingen, Germany
Nutrient limitation governs Staphylococcus aureus niche adaptation in the human
nose
11:30 Emanuel Hanski, Jerusalem, Israel
How pathogenic bacteria modulate host unfold protein response to regulate their own
sensing and proliferation
12:00 Sven Hammerschmidt, Greifswald, Germany
Regulation of the arginine deiminase system by ArgR2 couples pneumococcal
metabolism and virulence
12:20 Petra Dersch, Braunschweig, Germany
Host-adapted metabolic functions important for Yersinia pseudotuberculosis virulence
12:40 Christine Heider, Wernigerode, Germany
Stable isotope labelling reveals a distinctive role of glutamine during operation of the
Yersinia enterocolitica type three secretion system
13:00 Lunch
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Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
14:00 Busses to Varus battleground, Kalkriese
14:30 Arrival at Kalkriese
Coffee and refreshment provided
Session 6: Regulation of metabolism during host colonization, Chair: Michael Hensel
14:45 Kai Papenfort, Princeton, USA
Conserved and specific functions of the small regulatory RNA SgrS in Salmonella
15:15 Andrew Roe, Glasgow, United Kingdom
Sending pathogenic E. coli on an acid trip
15:45 David Clarke, Cork, Irland
Specific metabolic pathways in adherent-invasive Escherichia coli are required for
replication in the macrophage and activation of Il-1 production
16:05 Barbara Campanini, Parma, Italy
Blocking cysteine biosynthesis in Salmonella Typhimurium: the moonlighting enzyme
CysK as a potential antibiotic target
Coffee and refreshments provided
16:30 and 17:00
Quintili Vare, legiones redde! Guided tours to the Varus battleground
exhibition site
19.00 Dress like a Roman – demonstration of Roman clothing
19:30 Dine like a Roman - Conference Dinner
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Metabolism Meets Virulence 2
Osnabrück, 6.-9. April 2014
9. April 2014, Steigenberger Hotel Remarque
Session 7: Future challenges in host-adapted bacterial metabolism, Chair: Thomas
Dankedar
8:30
Nassos Typas, Heidelberg, Germany
From high-throughput approaches to molecular mechanism
9:00
Matthias Horn, Vienna, Austria
The metabolism of host-free chlamydiae
9:30
Alexander Westermann, Würzburg, Germany
Simultaneous gene expression analysis of pathogen and host by Dual RNA-seq
9:50
Wolfgang Eisenreich, Garching, Germany
Exploring pathways and interactions in the pathometabolism of bacteria
10:10 Namrata Iyer, Bangalore, India
Amino acid racemases: Novel regulators of Salmonella pathogenesis
10:30 Coffee break
Session 8: Modeling bacterial metabolism during infection, Chair: Wolfgang Eisenreich
11:00 Michael Lalk, Greifswald, Germany:
Metabolomics insights in infection-related adaptations of Staphylococcus aureus
11:30 Kyu Y. Rhee, New York, USA:
Mycobacterial metabolomics: towards a chemical understanding of essentiality
12:00 Thomas Dandekar, Würzburg, Germany
Modelling Metabolism in intracellular infections
12:20 Conclusion and closing remarks
Michael Hensel
12:30 Lunch (Lunch boxes on request)
Departure
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