Phylogenetic tree of bilaterian otx genes with aristaless (arx) as outgroup. Protein
sequences were obtained from the published literature or BLAST searches of the
NCBI GenBank. The tree is built with the amino-acid sequences from Maximum
likelihood analysis. The two orthologs of otx in chelicerates (named otxa and otxb in
Cupiennius) does not correspond to otx1 and otx2 of vertebrates showing that the
duplication of the genes in chelicerates had happened independently from
duplication of otx in vertebrates. Arthropods’ otx genes do not form a monophylum
and position of chelicerates’ two orthologs within the arthropods is unresolved.
Table S5 List of the species names, their phylum, and their abbreviation, the gene
names and the GeneBank accession numbers used in phylogenetic analysis of otx
genes.
Abbreviation
Aec_ocl
Accession info
EGI70731
Species name
Acromyrmex echinatior
Phylum
Arthropoda
Aga_otx
Ame_ocl
Api_otd
Bmo_arx
XP_310918
XP_006571327
XP_001948393
XP_004929200
Anopheles gambiae
Apis mellifera
Acyrthosiphon pisum
Bombyx mori
Arthropoda
Arthropoda
Arthropoda
Arthropoda
Bmo_otd
Cgi otx5
Cgr_otx2
Cpi otx2
Csa otxa
Csa otxb
Csa_arx
Dme_ocl
Dme_otd
Dre_otd1
Efl_otd
Eka arx
Eka_otd
XP_310918
EKC28141
ERE92634
XP_005295567
LN624820
LN624821
To be submitted
NP_001014727
CAA41732
NP_571325
AAU85255
CDK60408
LN650633
Bombyx mori
Crassostrea gigas
Cricetulus griseus
Chrysemys picta
Cupiennius salei
Cupiennius salei
Cupiennius salei
Drosophila melanogaster
Drosophila melanogaster
Danio rerio
Euscorpius flavicaudis
Euperipatoides kanangrensis
Euperipatoides kanangrensis
Arthropoda
Mollusca
Chordata
Chordata
Arthropoda
Arthropoda
Arthropoda
Arthropoda
Arthropoda
Chordata
Arthropoda
Onychophora
Onychophora
Gma_otd
Hsa_otx1
Isc_hox?
Laf_otx2
Lch otx2
Mdo_arx
Moc_otx1
Obi_otd
Pca_otd
Pre_otx1
Pte otd1
Pte otd2
Rno_otx1
Sca_otx2
Sma_otx
Smi_arx
Smi_otx1
Smi_otx2
Spa_otx2
Sra_ocl
Tca_otd1
Tca_arx
Tsa_otx
CAK50843
NP_055377
XP_002403318
XP_003408715
XP_005986517
XP_005181478
XP_003742052
AAZ99218
AFY12008
XP_008416164
AB096074.1
KP725073
NP_037241
AAP04272
ABY74501
KFM57110
KFM58880
KFM60429
XP_008281544
CEF62108
NP_001034513
XP_008193910
AAU85252
Glomeris marginata
Homo sapiens
Ixodes scapularis
Loxodonta africana
Latimeria chalumnae
Musca domestica
Metaseiulus occidentalis
Octopus bimaculoides
Priapulus caudatus
Poecilia reticulata
Parasteatoda tepidariorum
Parasteatoda tepidariorum
Rattus norvegicus
Scyliorhinus canicula
Strigamia maritima
Stegodyphus mimosarum
Stegodyphus mimosarum
Stegodyphus mimosarum
Stegastes partitus
Strongyloides ratti
Tribolium castaneum
Tribolium castaneum
Tegenaria saeva
Arthropoda
Chordata
Arthropoda
Chordata
Chordata
Arthropoda
Arthropoda
Mollusca
Priapulida
Chordata
Arthropoda
Arthropoda
Chordata
Chordata
Arthropoda
Arthropoda
Arthropoda
Arthropoda
Chordata
Nematoda
Arthropoda
Arthropoda
Arthropoda