Curriculum Vitae
DR.NANCY LOUIS WASSEF, IFCAP CSci
DipRCPath(eq) , MSc, MB BCh
UK General Medical Council Registered # 6153962
HCPC registered: CS 18393
International Fellow of College of American Pathologists and Member of American
Chemical Society (ACS)
Member of the Royal College of Pathologists, London, UK (# 0998323)
Member of Royal Society of Medicine, London, UK (#00622002)
Member of Association of Clinical Biochemists, London, UK (#09395)
Registered as Consultant Clinical and Chemical Pathology, Reg. # 732, 1999
Egyptian Medical Syndicate, Cairo-Egypt,
38 Parsley Close, Lower Earley
Reading, Berkshire, RG6 5GN
Tel: 01189 756 976
Mobile: 07901 710 243
Fax: 01189 756 976
E-mail Address: nancywassef54@gmail.com
KEY SKILLS
More than 20 Publications in the field of Plasma Cell Dyscrasias and Amyloidosis.
Solid experience in clinical pathology including Chemical Pathology, Microbiology,
Haematology, Blood Transfusion Medicine and related infection control processes
More than 30 years of experience in managing the laboratory. Involved in evaluation and
implementation of new procedures and equipment for the various laboratory’s sections.
Participated on a regular basis in educational activities in UK, KSA and in the Middle East.
Participated in the CPA, UK accreditation scheme
Participated in external quality assessment schemes for the laboratory, NEQAS and Biorad.
Ability to recruit / develop multi-disciplinary teams and achieve significant results
Ability to work on own initiative under pressure and to specific targets
Excellent communication, interpersonal and presentation skills - at all levels
Fluent in English, Arabic, French and basic German
Adapt well to challenges, resilient and tenacious
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Curriculum Vitae
PROFESSIONAL / CAREER
From 26/01/2015 to 31/05/2015: International Clinical Manager for Helena Biosciences
Europe
➢ To lead customer clinical support services both internationally and within the UK by
providing clinical training programs and promoting Helena’s flagship
➢Develop and secure new Helena businessinternationally and within the UK.
➢Facilitate the completion, clinical readiness, launch and installation of Helena’s major new
products portfolio
➢Attract, develop and secure major new business growth inthe UK and worldwide
➢Develop and complete scientific marketing, training literature and scientific publications for
all of Helena’s new and competitive product lines to increase domestic and international
sales.
From 01/05/2007 till 25/01/2015:
Head of Proteins and Enzymes Section
Principal Clinical Scientist
Clinical Biochemistry Department
Royal Free Hospital, London
➢
Responsible for the day-to-day comprehensive management, operation, supervision
and direction of the specialist service provided by the Protein and Enzymes department.
➢
I consult and liaise with clinicians (including senior medical staff) , on the complex
interpretation of biochemistry results and especially on differential diagnoses and monitoring
treatment by participating in DUTY OFFICERS rotas once every 7-10 days (see duty officer
training and competency log)
➢
Due to a colleague going on Maternity leave in 2008 and 2011, for 2 years Icovered
as the Head of Endocrine and RIA Section in addition to my responsibilities in the Proteins
laboratory (see duties in Endocrine Section paragraph)
❖ Duties and Responsibilities as Head of Proteins and Enzymes Section:
➢
A Total of 98,900 Protein specialised tests are performed in the Protein and
Enzymes Section annually. The Section is second busiest unit in the department after the
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Curriculum Vitae
Core lab. It has a vital role in supporting the diagnostic services and results interpretation to
the following departments:
1. National Amyloidosis Centre (NAC)
2. Renal & Dialysis Services
3. Haematology & Oncology Departments
4. Bone Marrow Transplant Services.
5. Rheumatology department
6. Primary Care
➢
Five principal work streams are identified in the combined operations of the Proteins
and Enzymes / Endocrine section along with some smaller volume assays, the main work
streams being:
• Electrophoresis – 35,000 samples per year
- Protein electrophoresis and Immunofixation
- Alkaline Phosphatase and CK Isoenzymes
• Nephelometry
- Serum Light Chains – 40,000 samples per year
- Serum Amyloid A – 5,000 samples per year
• Glycated Haemoglobin – 27,000 samples per year run by HPLC method.
• Vitamin D – 60,000 samples per year (moved to Core lab in Feb. 2012) run on
Liaison, Diasorin
• Immulite assays (Growth Hormone; IGF1; Androstendione)
The smaller volume, more infrequently scheduled assays are:
Endocrine assays
-17OH Progesterone by RIA
-Urinary Free Cortisol – pre-analytical extraction prior to processing on
the core lab E170
-Macroprolactin - pre-analytical extraction prior to processing on the
core lab E170
Miscellaneous Protein assays
- Cryoglobulins
-Porphyrin screens
-Faecal Occult Bloods
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Curriculum Vitae
-Urine dipsticks & Reducing substances
➢
Accountable for the quality assurance of the aforementioned tests including external
assessment and internal monitoring, taking corrective action where the need is identified. I
analyse data from External Quality Assessment Schemes such as NEQAS and
communicate performance to staff, as well as take appropriate corrective action where
relevant.
➢
Responsible for the direction, supervision and management as well as teaching and
training of scientific and technical staff working within the section.(see reference letters)
➢
Initiate and participate in clinical audits pertinent to the provision of the clinical
biochemistry service (See publications)
➢
Introduced and validated Serum Amyloid A assay in2009 and Capillary Zone
Electrophoresis method in 2011.
➢
Evaluated and introduced the Hevylite assay and assessed its clinical significance if
offered in our test repertoire.(see posters)
➢
Evaluated the new N- Latex free light chain method of Siemens and comparing its
performance against the Binding Site assay. (see Poster in IFCC EuroMedlab Milan 2013)
➢
Promoted and maintained close links with appropriate clinical departments and
teams by participating in National Amyloidosis Centre and Haematology MDT meetings.
➢
Reported and authorised results of protein and urine electrophoresis as well as Free
light chain and SAA.
➢
Ensured that management and operational performance data is monitored, for
example, turnaround times, workload and materials consumption and take corrective action
where necessary.
➢
Troubleshoot and organise appropriate corrective action when there is a situation
which may or has caused a service delivery failure.
➢
Maintained a system of records and documentation keeping for routine and research
work. I ensured all staff in the section keep records and Standard Operating Procedures upto-date, and that all records and documentation are maintained properly within a Total
Quality management system in order to maintain our CPA full accreditation status.
➢
Held regular section meetings in order to communicate and update staff with
changes within the section, the department as well as Trust wise.
➢
Disseminated knowledge gained during private study or research and develop
projects through presentation at local, national and international meetings and publications.
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Curriculum Vitae
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I maintain my CPD portfolio updated by attending meetings, seminars and training
courses in line to RCPATh guidance.(see CPD summary)
➢
Fire Warden and Deputy Health and Safety Officer of the department.
➢
I organised the first North London International Scientific Meeting (CPD accredited)
to talk about Laboratory Perspectives in the diagnosis of Plasma Cell and B Lymphoid
Dyscrasias
❖ DUTIES AS HEAD OF ENDOCRINE AND RIA SECTION
➢
I was responsible for the day-to-day comprehensive management, operation,
supervision and direction of the specialist service provided by the Endocrine and RIA
sections.
➢
Specialised tests performed on site: Growth Hormone, IGF1 and Androstenedione on
Immulite 1000, 17 Hydroxy progesterone, Vitamin D and Renin (RIA), Urine free Cortisol and
Macroprolactin.
➢
I authorised and interpreted results of Thyroid function tests, Sex hormones,
Parathyroid Hormone and Tumour markers
➢
I liaised with clinicians in hospital and with GPs, discussing and interpreting different
endocrine results (sex hormones, Thyroid functions) as well as Dynamic function tests such
as synacthen and Growth hormone/ glucose tolerance.
➢
I introduced and evaluated Vit D assay ( chemiluminescence method) on the Liaison
platform due to significant in increase in workload justifying the stopping of the manual RIA
method. Renin was also discontinued on site since workload figures did not justify the health
and safety risks undertaken to run RIA test.
➢
I wrote the Vit.D standard operating procedure as well as reviewed those of UFC and
Growth hormone.
➢
I attended to Thyroid clinic once a week.
➢
I performed Heterophile antibodies on sera of patients suspected to have thyroid
resistance as part of authorising results and helped the Section BMS2 in writing the SOP.
➢
Being the RIA Safety Officer, I supervised radioactive waste disposal in the
laboratory.
➢
I was responsible for monitoring the quality control of section and ensured that
appropriate corrective actions were taken when there was a situation which may or had
caused a service delivery failure
➢
I analysed data from External Quality Assessment Schemes such as NEQAS and
communicated performance, as well as took the necessary action when required.
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Curriculum Vitae
➢
I ensured that management and operational performance data were monitored
including turnaround times, workload and materials consumption and to take corrective
action where necessary.
➢
I trained and taught four trainee clinical scientists.
Publications, Posters and Oral Presentations:
❖
Published and Posters:
1. A 20 year single centre experience of aa amyloidosis demonstrating changes
in its epidemiology
Helen J Lachman, JD Gillmore, Ashutosh D Wechalekar, S.D.Gibbs, Janet
Gilbertson,Jenny Pinney, F.T.Hunt,,Dorota Rowczenio, Hadija Trojer, T. Lane, C. P.
Venner,Sanjay M Banypersad, D. Gopaul David F Hutt ,Nancy Louis Wassef , M. B.
Pepys , P. N. Hawkins
Annals of the Rheumatic Diseases (Impact Factor: 9.27). 01/2014; 71(Suppl 3):283-284.
DOI: 10.1136/annrheumdis-2012-eular.2344
2. Infusion of Pharmaceutical-Grade Natural Human C-Reactive Protein Is Not
Proinflammatory in Healthy Adult Human Volunteers
Thirusha Lane, Nancy Wassef, Stephen Poole, Yogesh Mistry, Helen J. Lachmann,
Julian D. Gillmore, Philip N. Hawkins and Mark B. Pepys
Circ Res. 2014;114:672-676
3. An EnIgMatic Paraprotein
Colyer SN, Wassef N
Nephrology Amyloidosis Day, RSM, London, September 2013
4.
Comparison of the analytical performance of the polyclonal antibody based
Freelite and monoclonal antibody based N Latex FLC assays in the detection of
multiple myeloma and AL amyloidosis
Wassef, N.L
IFCC EuroMedlab Milan 2013
5.
Utility of Heavy/Light chain ratio in patients with systemic AL amyloidosis
Berlnga O,Wassef N, et al.
IFCC EuroMedlab Milan 2013
6. Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome
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Curriculum Vitae
Pinney JH, Whelan CJ, Petrie A, Dungu J, Banypersad SM, Sattianayagam P,
Wechalekar A, Gibbs SD, Venner CP, Wassef N, McCarthy CA, Gilbertson JA,
Rowczenio D, Hawkins PN, Gillmore JD, Lachmann HJ.
J Am Heart Assoc. 2013 Apr 22;2(2):e000098. doi: 10.1161/JAHA.113.000098.
7. The role of immunological assessment in patients with acute kidney injury and
possible
myeloma
Helen J Lachmann, Nancy L Wassef
Advances in Chronic Kidney Disease,Volume 19, Issue 5 , Pages 287-290,
September 2012
7. Outcome in Renal AL Amyloidosis following Chemotherapy
Jennifer H. Pinney, Helen J. Lachmann, Loveleen Bansi, Ashutosh D. Wechalekar,
Janet A.
Gilbertson, Dorota Rowczenio, Prayman T. Sattianayagam, Simon
D.J. Gibbs, Emanuela
Orlandi, Nancy L. Wassef, Arthur R. Bradwell, Philip N.
Hawkins and Julian D. Gillmore
JCO Feb 20, 2011:674-681
8. Abnormal N-terminal fragment of brain natriuretic peptide in patients with light
chain amyloidosis without cardiac involvement at presentation is
a risk factor
for development of cardiac amyloidosis
Ashutosh D. Wechalekar, Julian D. Gillmore,Nancy Wassef, Helen J. Lachmann,
Carol Whelan and Philip N. Hawkins
Letter to the Editor, Haematologica 2011, 96(7)
9.
Transient increases in NT pro-BNP concentration during chemotherapy for AL
amyloidosis are associated with inferior long-term survival
Simon Gibbs, Prayman Sattianayagam, Jennifer Pinney, Carol Whelan, Jason
Dungu, Marna De Cruz, Helen Lachmann, Nancy Wassef, Julian Gillmore, Philip
Hawkins, Ashutosh Wechalekar
MS ID#: BLOOD/2011/361105
10. Validation of DFLC Method for Monitoring Clonal Responses in Systemic AL
Amyloidosis: Superior outcome of patients achieving >90% Response (VGPR).
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Curriculum Vitae
S. Gibbs, P. Sattianayagam, J. Gillmore, J. Pinney, N. Wassef, M. Offer, J.
Gilbertson, D. Rowczenio, T. Lane, C. Whelan, J. Dungu, A. Bradwel, H. Lachmann,
P. Hawkins, A.
Wwchalekar
13th International Myeloma Workshop, Paris 3-7 May,2011
11. 103 Senile systemic amyloidosis: a common cause of heart failure in the
elderly?
J H Pinney, H J Lachmann, J D Gillmore, A Wechalekar, S D J Gibbs, P
Sattianaagam, S M Banypersad, J Dungu, N Wassef, C A McCarthy, P N
Hawkins, C J Whelan
Heart 2011;97:A59-A60 doi:10.1136/heartjnl-2011-300198.103
12. An analysis of the endocrine disease associated with systemic AL
Amyloidosis
Gibbs, S, Vanderpump, M.P., Hutt, D,Sattianayagam, P, Pinney, J, Wassef,
N,Gillmore, J,
Lachmann, H, Hawkins, P, Wechalekar,A
15th Congress of the European Hematology Association, Paris,France, September
2010
13.Amyloidosis in patients with gastrointestinal neuromuscular disorder of the
gut
( GINMD) - comparison of serum and histopathological diagnostic
techniques
D.Chowdhury, N Wassef, A. Raimundo, A. Darzi , J. Martin, D.B.A. Silk
DDW 2010 by American Gastroenterology association, USA
14. Serum immunoglobulin heavy/light chain ratios (HevyLite) in patients with
systemic AL amyloidosis
Ashutosh Wechalekar, Stephen Harding, Helen Lachmann, Julian Gillmore, Nancy
Wassef,
Michael Thomas, Gibbs SDJ, Sattianayagam P, Whelan CJ, Arthur
Bradwell and Philip Hawkins
XII International Amyloidosis Symposium, Rome, Italy, April 2010.
15.A New Staging System for AL Amyloidosis Incorporating Serum Free Light
Chains, cardiac Troponin-T and NT-ProBNP
Ashutosh D Wechalekar, Nancy L Wassef, Simon DJ Gibbs, Julian Gillmore, Felicia
Dike, Helen Lachmann, Prayman Sattianayagam, Arthur Bradwell and Philip N
Hawkins
51 st ASH Annual Meeting, New Orleans, USA, December 2009.
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Curriculum Vitae
16. High early mortality and poor outcomes for patients with AL amyloidosis
having high presenting serum free light chains – a new risk stratification model
Ashutosh D Wechalekar, Nancy Wassef, Julian D Gillmore, Simon Gibbs, Prayman
Sattianayagam, Helen J Lachmann, Philip N Hawkins,
14th Congress of the European Hematology Association, Berlin, Germany, June
2009
17.Monoclonal protein detection in AL amyloidosis revisited - analysis of 642
patients
N L Wassef, JD Gillmore, HJ Lachmann, J Morris, M Thomas, AR Bradwell, G
Mead, PN
Hawkins, AD Wechalekar
XII International Myeloma Workshop, Washington, D.C., USA, February 2009.
18.Monoclonal protein detection in AL Amyloidosis re-visited. Analysis of 644
patients
N L Wassef, JD Gillmore, HJ Lachmann, J Morris, M Thomas, AR Bradwell, G Mead,
PN Hawkins, AD Wechalekar.
5th Euramy Meeting, Portugal, October 2008
19.Vitamin D levels and susceptibility to human rhinovirus exacerbations of
COPD
JA
JK Quint, GC Donaldson, JJP Goldring, A Patel, S Karmali, N Wassef, M Thomas,
Wedzicha
British Thoracic Society meeting, London, UK, December 2009.
20.Thyroid dysfunction in a Hepatitis C population treated with Interferon and
Ribavirin Combination Therapy in a UK cohort.
Costelloe, Seán; Wassef, Nancy; Josephine, Schulz; Vaghjiani, Tina; Whiting, S;
Thomas, Michael;Dusheiko, Geoffrey; Jacobs, Michael; Vanderpump, Mark
80th Annual Meeting of the American Thyroid Association, Florida-USA, September
2009
21. Vitamin D deficiency does not affect FEV1 decline in chronic obstructive
pulmonary disease
J K Quint, G C Donaldson, JJP Goldring, N Wassef, M Thomas and J A Wedzicha
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Curriculum Vitae
European Respiratory Society Conference, Vienna, Austria, September 2009.
22. Vitamin D deficiency does not affect exacerbation frequency in chronic
obstructive pulmonary disease
J K Quint, G C Donaldson, JJP Goldring, N Wassef,M Thomas and J A Wedzicha
European Respiratory Society Conference, Vienna, Austria, September 2009.
23. An audit of thyroid dysfunction in a Hepatitis C population treated with
Interferon
and Ribavirin at the Royal Free Hospital.
S J Costelloe, N Wassef, C Morris, J Schulz, T Vaghijiani, S Whiting, M Thomas,
G Dusheiko, M Jacobs, M Vanderpump
FOCUS Meeting, Liverpool, UK, May 2009.
24. Thyroid dysfunction in a Hepatitis C population treated with Interferon
therapy
S J Costelloe, N Wassef, C Morris, J Schulz, T Vaghijian, M Thomas, G Dusheiko, M
Jacobs, M Vanderpump
British Endocrine Society meeting, Harrogate, March, 2009.
PRESENTATIONS:
❖ Plasma Cell Dyscrasias and Electrophoresis
Egyptian Society of laboratory Medicine International Conference,Cairo, April 2015
Helena Distrubutors Training Day, February 2015
❖ Haemoglobinopathies and Haemoglobin Electrophoresis
Egyptian Society of laboratory Medicine International Conference, Cairo, April 2015
❖ Immunofixation and Immunodisplacement Training
UGM Staff, Cairo, April 2015
Sysmex Staff, Netherland, March 2015
Helena Education Day, Newcastle, March 2015
❖ The Importance of Both: Electrophoresis and Free Light Chain Assay
Helena International Users Group meeting, Barcelona, September 2014
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Curriculum Vitae
❖ Amyloidosis in the UK
Sebia User Group, Birmingham, September 2014
❖ Amyloidosis in UK
Egyptian Society of laboratory Medicine International Conference, Cairo, April 2014
❖ Pitfalls of Electrophoresis
Egyptian Society of laboratory Medicine International Conference, Cairo, April 2014
❖ Using Electrophoresis as a Diagnostic Tool: Clinical Case Studies
Arab Health Exhibition Dubai, January 2014, organised by Helena Biosciences Europe
❖ Laboratory Perspective in Diagnosing and Monitoring Plasma Cell Dyscrasias
Helena Electrophoresis Education day, Royal College of Pathologists, November 2013
❖ Amyloidosis in the UK
Helena International User Group, Paris, October 2013
❖ A case study: Myeloma case
Journal Club, Royal Free Hospital, London, March 2013
❖ Unexpected Haemoglobin A1c Results
Journal Club, Royal Free Hospital, London, June 2011
❖ The Demise of BJP or Not? How the audit was conducted,
Royal Free Hospital, London, June 2007
❖ Glycated Haemglobin, pitfalls in its determination,
Royal Free Hospital, London, April 2007
COURSES, CONFERENCES AND MEETINGS:
❖ 2015

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
Egyptian Society of laboratory Medicine International Conference,Cairo,
April 2015
Training Staff and Distributors worldwide on CZE, Immunofixation and
Immunodisplacement interpretation
Arab Health Exhibition, Dubai, January 2015
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Curriculum Vitae
❖ 2014
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Leadership in Healthcare Training Course, Oct.2013 - July,2014 , Royal Free
Hospital.
International User Group (Helena),Barcelona, September 2014
Sebia Users’ Group meeting, Birmingham, September 2014
Helena Education Day, York, May 2014
Egyptian Society of laboratory Medicine International Conference,Cairo, April
2014
6th UK Amyloidosis Network Workshop, Royal Free Hospital, London, February
2014
Arab Health Exhibition, Dubai, January 2014
❖ 2013
▪
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▪
▪
International User Group (Helena), Paris, October 2013
Myeloma Amyloid day, RSM, London September 2013
20th IFCC- EFLM European Congress of Clinical chemistry, Milan,May 2013
5th UK Amyloidosis Network Workshop, Royal Free Hospital, London, February
2013
❖ 2012
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Laboratory Perspectives in the Diagnosis of Plasma Cell Dyscrasias, Royal
Free Hospital, London, June 2012
Body Weight Management, Facts and Myths, Royal Free Hospital, London,
March 2012
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Analytical Investigations into Inherited Metabolic Disease, Royal Free Hospital,
London, February 2012
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Vitamin D in Kidney Stone Formers, Royal Free Hospital, London, January 2012
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Trimethyaminuria, Royal Free Hospital, London, January 2012
❖ 2011
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Design and Analysis of Studies in Healthcare, UCLH, London, September 2011
AST: Should we remove it from the LFT Profile, Royal Free Hospital, London,
September 2011
Steroids and the Stress Response, Royal Free Hospital, London, January 2011
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Curriculum Vitae
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ACB Spotlight, Controversies & Changes in Immunoglobulins, RCPATh,
London, 2011
IRR99 Training, Royal Free Hospital, London, 19 July 2011
Chemical Awareness and Emergency Spill Response, Royal Free Hospital,
London, 5 July 2011
Capillary Electrophoresis Training , Sebia UK, June 7-8, 2011
Presented : “Unexpected Haemoglobin A1c Results” Royal Free Hospital,
London, May 2011
POCT at the Royal Free, Royal Free Hospital, London, May 2011
Endocrinology Investigations, Royal Society of Medicine, London, May 2011
Low Potassium: How to investigate, Royal Free Hospital, London, March 2011
Multiple Myeloma: Review of Guidelines, Royal Free Hospital, London, March 2011
Introduction to Informative Governance, DoH, online training, London, March
2011
The Role of Caldicott/IG Lead in General Practice, DoH, online training, London,
March 2011
Low Sodium: How to investigate, Royal Free Hospital, London, March 2011
Clinical Cases Presentation, Royal Free Hospital, London, March 2011
FH- National Audit Site Report, Royal Free Hospital, London, February 2011
Competent Persons (General Risk Assessors) Seminar, Royal Free Hospital,
London, February 2011
Updated Chest Pain Protocol, Royal Free Hospital, London, January 2011
❖ 2010
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BNII Training, Siemens, Frimley Park, UK,, December 2010
Clinical Applications of Serum Free Light Chains, Bath, September 2010
Business Process improvement Workshop, Roche, Burgess Hill, June 2010
Siemens
Academy Laboratory Managers', Manchester June2010
Managing change Workshop, Roche, Burgess Hill, May 2010
ICPMS-What, Why, Where, How and When, Royal Free Hospital, London, May
2010
A guide to EQA, Royal Free Hospital, London, April 2010
Training on BN ProsPec instrument, Siemens,Frimley Park, UK, March 2010
Portfolio of instruments, Royal Free Hospital, Clinical Biochemistry, March 2010
❖ 2009
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Recent Advances in the Management of Free Light Chain Disease, Ashford,
May 2009
NeuroEndocrine Tumour Markers, Royal Free Hospital, London, May 2009
Modernising Scientific Careers, Royal Free Hospital, London, April 2009
Clinical Audit, Royal Free Hospital, London, April 2009
Glucose Audit, Royal Free Hospital, London, March 2009
Reagents Inventory Management schemes, Royal Free Hospital, London, March
2009
GCP in a nutshell, Royal Free Hospital, London, March 2009
Cryoglobulins, a very British case, Royal Free Hospital, London, February 2009
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Curriculum Vitae
● Screening for Novel components of Intracellular Signalling pathways,
Royal Free Hospital, London, February 2009
❖ 2008
● Customer awareness programme, Royal Free Hospital, London, December 2008.
● MedScape online CME, London, November 2008
● Lessons from the Jupiter Study: Statins moving to another planet?
Royal Free Hospital, London, November 2008.
● Thyroid Audit, Royal Free Hospital, London, October 2008.
● The Role of Vitamin D in COPD, Royal Free Hospital, London, September 2008.
● Aspects of HbA1c and Haemoglobinopathies, Keble College, Oxford, September
2008.
● Promoting clinical Governance through effective Management course, Royal
Free Hospital, London, July 2008
● ACB Management and Leadership Course, University of Surrey, School of
Postgraduate Medical Education, June 2008.
● EQMS System Overview, Royal Free Hospital, London, June 2008
● Cardiovascular risk assessment in HIV patients attending a designated lipid
clinic, Royal Free Hospital, London, June 2008
● The role of biochemical monitoring in renal failure and dialysis, Royal Free
Hospital, London, June 2008
● Evidence based Endocrinology, London, RSM, May 2008.
● Festschrift for Paul Sweny, Royal Free Hospital, London, May2008
● Diagnosis of Phaeochromocytoma, Royal Free Hospital, London, March 2008.
● Primary Hyperoxaluria, Royal Free Hospital, London, February 2008.
● Serum Free Light Chain Assay and monoclonal gammopaties, Royal Free
Hospital, London, February 2008.
● Mitochondrial disorders for the non initiated, London, RSM, January2008.
❖ 2007
●
Preliminary results of Urgents audit symposium, Royal Free Hospital, London,
December 2007.
● NT-BNP and Amyloidosis symposium, Royal Free Hospital, London, November
2007.
● Natural Evolution and Engineering of Transketolase, Royal Free Hospital,
London, November 2007.
● Critical issues in Cardiovascular risk management, London, RSM, September
2007.
● Clinical aspects for Protein Assays, and workshop,Royal Holloway College,
University of London, September 2007.
● Aspects of HbA1c and Haemoglobinopathies, Keble College, Oxford, July 2007.
● What’s New in Immunology, Birmingham, May 2007.
● Using Electrophoresis Techniques to Their Full, Warwickshire, March 2007.
● Diagnosis of Lysosomal Storage Disorders in The Enzyme Laboratory,
Royal Free Hospital, London, February 2007.
❖ 2006
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Quality Management Systems and Internal Auditing in the Clinical Pathology
Laboratory, One day training course, Royal Free Hospital, London, November 2006.
From Nov 1989 to Aug 2004:
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Clinical Pathologist and Director of
PathologyServices and Blood Bank
Head of Infection Control Committee
GNP Hospital, Jeddah, KSA
GNP Hospital, where I worked previously for the last 16 years, is a Private sixty beds’
hospital with A&E and an Outpatient Department including Diabetes and Obesity
clinics. It had many specialities including Endocrinology, Cardiology, Paediatrics,
Gastroenterology, as well as Obstetrics and Gynaecology, ENT, and general Surgery
Departments.
The Clinical Laboratory that I headed included Clinical Chemistry, Microbiology,
Serology, Haematology and Blood Transfusion sections.
The Hospital and the laboratory were recognized as referral centres for ALL
British and American expatriates, as well as for British, Canadian and
Australian Consulates pre-immigration laboratory works.
I was directly reporting to the Clinical Medical Director of the hospital as Head of
Pathology Department.
I orchestrated a multi-disciplinary team comprising a laboratory registrar (M.B.B.Ch)
under training, one BMS-2 and six BMS -1, two MLAs and a secretary. The lab was
run on an 8hours shift basis, 24 hours a day, 7 days a week. We performed
approximately 8000-10,000 clinical biochemistry tests monthly.
Since I started, I initiated the laboratory automation and expansion from a small sized
lab to a medium workload one.
When I started in GNP Polyclinic, the laboratory had only a small Coulter analyser (5
parameters),one Vitros DT 60, Dry chemistry , a Quantum analyzer (Abbott) for HIV
serology and Microbiology work was manual. There was no Blood transfusion.
Being in charge of the lab, I championed its upgrade to a medium sized lab suitable
for a 60 bed Hospital. I introduced and validated the following tests and methods:
Axsym system for Endocrinology, Tumour and Cardiac markers (TFT, sex hormones,
Prolactin,Troponin, BNP, Ca125, CEA, PSA, FPSA) as well as other infectious
immunoassays such as HIV, Hepatitis antigens and antibodies ,Cytomegalovirus and
Infectious Mononucleosis Serology.
IMX-Abbott, on which we ran HbA1c samples, and was the back up for Chemistry as
Vitek 32 (Biomerieux) was for serology tests. Growth hormone and IgF1 were referred
to Bioscientia, CAP accredited-Germany, since workload was not cost justified.
Vitros 950 (Johnson & Johnson) which was replaced later by VitrosFusion (Johnson &
Johnson) for routine Clinical chemistry. Vitros 250 (Johnson & Johnson) was the
backup instrument.
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ABL5 gas analyzer
Clinitek for urine strips.
Additionally I introduced I Stat - Abbott diagnostics as point of care devices
Advia 120 and Coulter HMX for Haematology routine full blood count.
Electra 1400 Hemoliance for coagulation studies.
Minividas (Biomerieux) for API system for microbiological isolation and identification of
different micro-organisms.
Dia Med system for Blood transfusion.
➢ The Laboratory participated in an External Quality Assessment scheme through Biorad
and IQC were strictly run daily following Westgard rules.
➢ Esoteric tests and other tests not performed on site were referred to CAP accredited
Bioscientia referral laboratory in Germany. These included Protein Electrophoresis,
A1AT phenotype and genotype, BRCA-I & II and others.
❖ Experience in Chemical Pathology:
➢ Reported and authorised 250-300 Multidisciplinary report s per day for patients
attending our outpatients clinics and in-patients.
➢ Since Inborn errors of metabolism features largely in Saudi Arabia and I frequently
consulted with paediatricians and specialists in problematic cases .
➢ Consequently I was first to introduce the screening programme for Neonatal
Hypothyroidism and PKU deficiency in GNP hospital.
➢ I started the pre marital full check up and screening for hereditary and inborn errors
of metabolism in the hospital since Co-sanguinous marriage is prevalent in the gulf
area and Middle East.
➢ I had access and discussions, on a regular basis, with Consultants from King Abdul
Aziz University (KAU), Jeddah, who have special interests in the diagnosis and
management of hyperlipidaemia.
➢ Diabetes features very predominantly in Saudi Arabia, and I have been involved in
the choice and implementation of point of care devices (I Stat - Abbott diagnostics,
and Clinitek-Bayer Diagnostics) for the diabetic population who visited the clinics.
● I also worked with two consultants with interests in Endocrinology and advised them
especially on interpretating Thyroid function tests and differential diagnosis of
problematic cases of Amenorrhea and hirsutism.
● I liaised with all the Hospital departments as well as others outside the Hospital
● I took part regularly in club meetings hosted on a rotational basis with the hospitals
in Jeddah.
❖ Management and Administrative responsibilities:
➢ I had the responsibility for the financial management of the laboratory. This included
the evaluation of appropriate fiscal measures to ensure effective laboratory use.
● I also encouraged a discriminating use for the laboratory resources with the
clinicians by providing advice to clinical staff on the use, choice of tests and
interpretation of results on patients with endocrine and lipid disorders.
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I held departmental weekly meetings with laboratory staff to discuss Health and
Safety matters, quality assurance program as well as any clinical incident report.
I held regular monthly meetings with clinical staff and liaised with different
departments in the hospital to ensure appropriate and rational use of the laboratory
through auditing.
I attended to regular meetings in Jeddah and Egypt as Continuing Professional
Development as well as in the Royal College of Pathologist
I coordinated teaching programs for technical and nursing staff regarding Health and
Safety, Infection Control and any other scientific advances in the laboratory.
I encouraged continuing professional development of laboratory personnel and held
fortnightly seminars in the laboratory to discuss different analytes, their use and
pitfalls of their measurements.
Engaged in teaching and training King Abdul Aziz University students of Biochemistry
(see Certificate)
I initiated, wrote and maintained Standard Operating Procedures Manuals for All
Laboratory analytes and procedures.
Participated in Saudi Western Region Quality Programme (MRQP), organised by the
Ministry of Health (KSA), as Quality Coordinator.(see Certificate)
The Laboratory under my management was accredited by Bioscientia, Germany,
having met all the international medical standards as duly authorized Referral
Laboratory.(see Certificate)
❖ Experience in Haematology and Blood Transfusion Medicine:
➢ Provided advice on all cases of Haematology, diagnosing and coordinating with other
colleagues in the treatment of benign haematology cases as well as running The
Coagulation clinic.
➢ Blood film Morphological Assessment and Malaria screening.
➢ Referring any cases suspected of haematological malignancy or plasma cell
Dyscrasia to Specialised Centres within the Kingdom.
➢ Blood Bank Director for 15 years, screening 1000 donors per year and supervising
bleeding processes, adhering to strict Saudi Ministry quality standards adapted from
Standards of the American Association of Blood Banks.Initiated Quality Assessment
Programme within separate component preparation units, utilising DiaMed system.
➢ High volume of liaison with Blood Bank Supervisor, resolving problematic cases.
➢ Reviewed all transfusion reactions and initiated / implemented procedures for blood
usage as integral member of Hospital Transfusion Committee.
❖ COURSES, CONFERENCES AND MEETINGS:
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Total Quality Management in Health Care, Training course and workshop
King Abdul Aziz University, Jeddah, Saudi Arabia, March 2004.
International Blood Transfusion Medicine Symposium, King Abdul Aziz
University, Jeddah, Saudi Arabia, March 2004.
Pall Quality control of Blood Components Workshop. King Abdul Aziz University,
Jeddah, Saudi Arabia, March 2004.
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Obesity & Diabetes- A Regional Epidemic Symposium Arab Health Exhibition,
Dubai UAE, January 2004.
Transfusion Medicine Symposium Erfan & Bagedo Hospitals, Jeddah, Saudi
Arabia, March 2003.
Intensive Course in Post-graduate Haematology
under the Auspices of the Royal College of Pathologists, London. King Abdul Aziz
University, Jeddah, Saudi Arabia, October 2002.
Recent Advances in Clinical Laboratory Medicine
Royal College of Pathologists, Jeddah, Saudi Arabia, October 2002.
Understanding Metabolic Medicine Royal College of Pathologists, London,
September 2002.
What Cardiologists expect from The Laboratory Symposium Erfan & Bagedo
Hospitals, Jeddah, Saudi Arabia, and January2002.
Laboratory Quality Assurance Workshop King Faisal Specialist Hospital and
Research Centre, Riyadh, Saudi Arabia, October 1998.
Laboratory Quality Assurance, King Faisal Specialist Hospital, Riyadh, KSA,
October 1998
Advances in Laboratory Medicine, King Khalid National Guard Hospital, Jeddah,
KSA, January 1994
A Short Refresher Course on Infectious Diseases, King Khalid National Guard
Hospital, Jeddah, KSA, February 1993
From August 1986 to October 1989: Maternity leave & career break (in Paris).
From September 1985 to July 1986:Specialist Clinical & Chemical Pathologist
Al Ali General Hospital
Riyadh, KSA
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208 beds’ private hospital.
I performed Clinical Pathologist work mainly in Clinical Biochemistry.
initiated the Standard Operating Procedures of the laboratory.
I assisted the clinicians in requesting their tests and helped them in reaching
diagnosis, especially in renal and internal medicine clinics.
➢ Helped the Hospital’s Dutch management in recruiting doctors from different
specialities.
(See Reference)
From May 1985 to August 1985: Trainee Chemical Pathology
Erfan & Bagedo General Hospital
Jeddah, KSA
King Fahad St. (Al Sitteen)
P.O.Box 6519 Jeddah 21452 – K.S.A.
Tel: 6038888
Hospital's Fax: 6917747
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P.R. Fax: 6621093
info@erfanhospital.com
p.r@erfanhospital.com
➢ Erfan & bagedo Hospital is a private tertiary hospital. The hospital runs 24 hours
services, 7 days a week with an Emergency 24 hours service
➢ Daily outpatient census range from 1,600 to 1,800 patients.
➢ Daily inpatient census is 170 to 200 patients.
➢ While training there, under the supervision of Dr Baher Saad Badawi, FRCPATh and
Director of laboratories, I gained a good grasp of the clinical aspects of different
diseases and their differential diagnosis through proper laboratory results’
interpretation.
➢ Acquired experience in different diagnostic techniques and principles of a wide range
of analytical equipment in the laboratory, for routine Chemistry, Endocrinology,
Haematology and Infectious diseases.
➢ Dealt with different analytical instruments: Kodak DT60, Ektachem 250, Cobas-Bio,
SMA analysers, Quantum, Axsym, Coulter &Cell dyne.
➢ Gained an excellent concept of laboratory External Quality Assessment and
participated in various workshops regarding this subject.
➢ Assisted training and teaching of newly assigned doctors & technicians.
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Participated in the ward rounds such as Paediatric& Diabetic clinics as
well as worked and interpreted the results of blood gas analysis in ICU.
From Dec.1984 to Apr.1985:
Career Break (KSA).
From May1983 to Nov.1984: Study Leave to prepare for MSc project
and exams.
Title: Measurement of Free Erythrocyte Protoporphyrin in Children with Microcytosis.
From Mar.1979 to May, 1983
Ain Shams University Hospitals, Cairo
Doctor of Blood Transfusion and Laboratory
➢ I worked as Doctor of blood transfusion and Laboratory while studying for my Master
degree in Clinical and Chemical Pathology.
➢ In addition to my work in Ain Shams University Hospitals, I spent a mandatory
timeof 2 years and attended to lectures and practical sessions in the disciplines
of general chemical pathology laboratories gaining experience with different
photometers, spectrophotometers, ASTRA analyzer, electrophoresis unit, and ICU,
as well as diabetic and paediatric clinics where patients came on a day-care basis,
for examination, follow up and treatment.
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Curriculum Vitae
➢ I participated in teaching and training postgraduates assigned to the hospital’s
general laboratories and attended to various lectures and workshops during the
period of my training.
➢ I learned and applied fundamental statistical concepts as well as Quality
management and how to appropriately use laboratory data with Prof. Samir Hanna
Sadek, FRCPATH.
➢ I learned and gained practical experience in principles of automation and
instrumentation, including general laboratory techniques and procedures, supplies,
volumetric equipment, and units of measurements with Prof. Laila Osman .
➢ I learned and got trained on how to establish and use reference values as well as
evaluating new methods to introduce in the laboratory Quality assurance and
management.
➢ Specimen collection and processing and gaining experience in the sources of
biological variation.
➢ I covered mostly all theoretical areas of Chemical Pathology including management,
Quality Control, Carbohydrates, Lipids, Proteins , Enzymes, Calcium and phosphate
metabolism Nitrogen metabolites and renal function, liver functions, gastric
pancreatic and intestinal function and Biochemical aspects of Haematology
➢ I rotated in all areas of practical chemical pathology as follows:
Routine Clinical Chemistry laboratory, Proteins electrophoresis Unit, Emergency
Laboratory, Endocrinology Unit, Immunology Section, Electrolytes and blood gases in
ITU and finally therapeutic drug monitoring and analysis of toxic substances in our
newly opened, then, Toxicology and Forensic Unit.
ADDITIONAL INFORMATION
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Trilingual: Fluent in French, English and Arabic
Certified Karuna Reiki Energy Healer and Master by The International Centre for
Reiki Training 21421 Hilltop Street, Unit No. 28. Southfield, Michigan 48034. U.S.A.
Presented a speech about Reiki and its healing effects, titled "Hands of Light",
during the International British/American Women Group meeting in January 2004.
Same Presentation done in Asian Women Group meeting in Jeddah, February 2004,
and in Palestinian Women Group In April 2004
Spearheaded numerous counselling and healing support groups among expatriate
and Saudi women in Jeddah.
PERSONAL INFORMATION
Nationality: British
Interests:
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Alternative complementary medicine and healing techniques.
Reading about different cultures and philosophy books
Charities and social events organising.
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Curriculum Vitae
REFERENCES AVAILABLE UPON REQUEST
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