CF Faculty Members (Currently Active)
Please note that although one grant, publication or project is listed for each CF Center faculty member, most CFRC faculty have numerous grants or contributions in multiple areas
relevant to cystic fibrosis.
Director: Eric J. Sorscher, M.D.
Office: (205) 934-9640
Fax: (205) 934-7593
Email: sorscher@uab.edu
Last Name
First Name
School
Dept/Division
Example of Recent Role in CFRC
Abraham*
Edward
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
Active CF Grant
(NIH NIGMS R01GM087748; HMGB1 and Neutrophil Efferocytosis)
AccavittiLoper
Mary Ann
Medicine
Genetics & Translational
Medicine
Recent CF Abstract: Chung et al. Towards Development of conformationally sensitive
monoclonal antibodies raised against full-length CFTR. NACFC 2011.
Aller*
Stephen
Joint Health
Sciences
Pharmacology &
Toxicology
Active CF Pilot Project (NIH NIDDK P30DK72482; Structure-based correction of the
major defect in cystic fibrosis)
Antony
Veena
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
Director of Adult CF Center
Atigadda
Venkatram
Arts &
Sciences
Chemistry
Synthesized more than 20 potential new compounds intended for CFTR activation.
Barnes*
Stephen
Joint Health
Sciences
Pharmacology &
Toxicology
Active CF Pilot Project (CFF R464-CR07; Analysis of CFTR Post-Translational
Modification by Mass Spectrometry)
Bebok*
Zsuzsanna
Joint Health
Sciences
Cell Biology
Active CF Grant (NIH NHLBI R01HL076587; CFTR Biogenesis and Function in
Epithelia)
Bedwell*
David
Joint Health
Sciences
Microbiology
Active CF Grant (P30DK072482: Core B (Animal Models Core) Director)
Berdiev
Bakhrom
Joint Health
Sciences
Cell Biology
Active CF Grant (NIH NHLBI R21HL085112; Regulation of Epithelial Sodium Channel
by CFTR Chloride Channel)
Blalock*
J. Edwin
Joint Health
Sciences
Physiology & Biophysics
Active CF Grant (NIH NHLBI R01HL077783; A New Pathway for Neutrophil-Induced
Airway Inflammation)
Bolger
Graeme
Medicine
Medicine - Hematology &
Oncology
Recent CF Manuscript: Pyle et al. Regulatory domain phosphorylation to distinguish
the mechanistic basis underlying acute CFTR modulators. AJP-Lung, 2011, In press.
Brouillette*
Christie
Arts &
Sciences
Chemistry
Active CF Grant (CFF BROUIL07XX0; Recombinant CFTR: Cooperativity and
Structural Domains)
Caldwell*
Guy
Joint Health
Sciences
Neurobiology (UAB) &
Biological Sciences (U of
Alabama)
Active CF Pilot Project (NIH NIDDK P30DK72482; Investigation of torsinA modulation
as a therapeutic strategy for cystic fibrosis)
Last Name
First Name
School
Dept/Division
Example of Recent Role in CFRC
Christian*
Becky
Nursing
Community Health
Outcomes & Systems
Active CF Pilot Project (UAB CCTS; Making Connections: Improving quality of life in
adolescents with cystic fibrosis)
Chung*
Wook Joon
Joint Health
Sciences
Neurobiology
Active CF Grant (NIH NINDS R21NS067693; A Novel Cell-Based Imaging Assay to
Identify Chemical Correctors for F508del CFTR)
Clines*
Greg
Medicine
Medicine - Endocrinology, Active CF Grant (NIH NIAMSD R21AR056826; CF Bone Disease: Convergence of
Diabetes, & Metabolism
CFTR and PTH Signaling)
Collawn*
James
Joint Health
Sciences
Cell Biology
Active CF Grant (NIH NIDDK R01DK60065; Cell Biology of CFTR in Polarized
Epithelia)
Crain*
Marilyn
Medicine
Pediatrics – Infectious
Disease & Virology
Active CF Pilot Project (NIH/NIDDK P30DK72482; Mucoid Streptococcus pneumoniae
in the CF Lung)
Dashiff
Carol
Nursing
Family, Child Health,
Caregiving
Recent CF Abstract: Dashiff et al. The experience of cystic fibrosis related diabetes
among adolescents and their parents and the influence of parental support. American
Diabetes Association Scientific Sessions, Orlando, 2010.
DeLucas*
Lawrence
Optometry
Optometry
Active CF Grant (CFF DELUCA06XXO; Crystallization and Structure Determination of
Full-Length CFTR Protein)
Dransfield
Mark
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
CFRC Funding (Relationship between CFTR activity and bioelectric function in
inflammatory and muco-obstructive lung disease)
Engler
Jeffrey
Graduate
School
Associate Dean
CFRC Internal Advisory Committee
Falany
Charles
Joint Health
Sciences
Pharmacology &
Toxicology
Recent CF Manuscript: Falany et al. Regulation of hepatic sulfotransferase (SULT)
1E1 expression and effects on estrogenic activity in cystic fibrosis (CF). J Steroid
Biochem Mol Biol. 114:113-9, 2009.
Fanucchi*
Michelle
Public Health
Environmental Health
Sciences
Recent CF Abstract: Tuggle et al. Early life exposure to ozone alters airway epithelial
responses in wild-type and cystic fibrosis transmembrane receptor (CFTR) knockout
mice. Pediatric Pulmonology Supp 33 (Abst 133), 2010.
Fu
Lianwu
Joint Health
Sciences
Cell Biology
Recent CF Manuscript: Bartoszewski R et al. CFTR expression regulation by the
unfolded protein response. Methods Enzymol 491:3-24, 2011.
Fuller*
Catherine
Joint Health
Sciences
Physiology & Biophysics
Active CF Grant (NIH NIDDK 2R01DK037206; Sodium Entry into Amiloride-sensitive
Epithelia)
Gaggar*
Amit
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
Active CF Grant (NIH NIDDK R01HL102371; A Novel Proteolytic System of
Pulmonary Inflammation)
Gutierrez*
Hector
Medicine
Pediatrics - Pulmonary
Active CF Pilot Project (NIH NIDDK P30DK072482; Statistical Process Control (SPC)
- validated home spirometry for CF lung disease)
Hathorne
Heather
Health
Professions
Clinical and Diagnostic
Sciences
Recent CF Abstract: Lui et al. “Normative values and receiver operating
characteristics of NPD for diagnostic measurements.” Pediatric Pulmonology Supp 33
(Abs 247), 2010
Last Name
First Name
School
Dept/Division
Example of Recent Role in CFRC
Harris*
W. Thomas
Medicine
Pediatrics - Pulmonary
Active CF Project (NIH NHLBI 1K08HL111419; TGF-βeta Dependent Myofibroblast
Transformation in CF)
Hartman IV*
John
Joint Health
Sciences
Genetics
Active CF Grant (CFF R464 Component 2: Research Training Core; Genome-wide
approach in S. cerevisiae to identify phenotypic modifiers of CFTR-F508del)
Hill
Aubrey
Arts &
Sciences
Computer & Information
Science
Recent CF Manuscript: Solomon et al. An international randomized multicenter
comparison of nasal potential difference techniques. Chest 138:919-28, 2010.
Hong*
Jeong
Joint Health
Sciences
Cell Biology
Active CF Grant (CFF R464-CR07 Core B (CFTR Expression Core) Director)
Hoover*
Wynton
Medicine
Pediatrics
Active CF Grant (CFF/UNC Characterization of MRSA Infection/colonization in Cystic
Fibrosis (STAR CF))
Ivey
Jean
Nursing
Family, Child Health,
Caregiving
School of Nursing Liaison to CF Training Programs
Jackson*
Patiricia
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
Active CF Pilot Project (CFF R464-CR11; Modulation of small matrikines by reactive
aldehydes in CF)
Judd
Suzanne
Public Health
Biostatistics
Awarded a CFF Grant (2011): Vitamin D for Multiple Health Outcomes in Cystic
Fibrosis
Kappes*
John
Medicine
Medicine - Hematology &
Oncology
Active CF Grant (NIH NIGMS R01GM095639; Production & Crystallization of
Membrane Protein for 3D Structure)
Keeling*
Kim
Joint Health
Sciences
Microbiology
Active CF Pilot Project (NIH NIDDK P30DK72482; Effect of NMD Repression on the
Suppression of CFTR Nonsense Mutations)
Kincaid
Harold
Arts &
Sciences
Philosophy
Previous director, Center for Ethics and Values in Sciences; CFRC was a founding
supporter and continues to support this initiative.
Kirk*
Kevin
Joint Health
Sciences
Physiology & Biophysics
Active CF Grant (NIH NIDDK R01 DK56798; New Paradigms of CFTR Regulation)
Liu*
Gang
Medicine
Medicine - Pulmonary,
Allergy, Critical Care
Active CF Grant (NIH NHLBI 1R21HL097218; MicroRNAs, inflammation, and acute
lung injury)
Lowman
John
Health
Professions
Physical Therapy
CFRC-funded pilot project to study the role of exercise in CF pathogenesis
Macrina
David
Education
Human Studies
Advisor to Children's Hospital Pulmonary Care Center
Marchase
Richard
Central
VP for Research &
Administration Economic Development
CFRC Internal Advisory Committee
Matalon
Sadis
Medicine
Recent CF Manuscript: Lazrak et al. Enhancement of alveolar epithelial sodium
channel activity with decreased CFTR expression in mouse lung. AJP-Lung, 2011, In
Press.
Anesthesiology
Last Name
First Name
School
Dept/Division
Example of Recent Role in CFRC
McClintock
James
Arts &
Sciences
Biology
CFRC Internal Advisory Committee
McGiffin
David
Medicine
Cardiac Surgery
Recent CF manuscript: Flume et al. Cystic fibrosis pulmonary guidelines: pulmonary
complications: hemoptysis and pneumothorax. AJP-Crit Care Med 182: 298-306,
2010.
McNees
Patrick
Health
Professions/
Nursing
Associate Dean for
Research
CFRC Internal Advisory Committee
Mrug
Sylvie
Arts &
Humanities
Psychology
Active Project in parental and child coping in CF.
Muccio
Donald
Arts &
Sciences
Chemistry
Recent CF Manuscript: Jackson et al. A CXCL8 receptor antagonist based on the
structure of N-acetyl-proline-glycine-proline. Eur J Pharmacol. 2011, In Press.
Piazza*
Gary
SRI
Molecular Library
Screening Center
Active CF Pilot Project (CFF R464-CR11; Spectral Domain Optical Coherence
Tomography for the Functional Characterization of Ion Transport Modulators)
Postlethwait
Ed
Public Health
Environmental Health
Sciences
Advisor to NIH F30ES14987; Effects of ozone on CFTR Expression and HIF Signaling
Rodgers
Theresa
Nursing
Family, Child Health,
Caregiving
Contributed to National CFRD (Cystic Fibrosis Related Diabetes) Management
Guidelines and provides training in CF Care.
Rowe*
Steve
Medicine
Pulmonary, Allergy,
Critical Care
Active CF grant (CFF ROWE10XX0; Mechanistic Link Between Rescue of CFTR
Mediated Anion Transport) *
Schwiebert
Lisa
Joint Health
Sciences
Physiology & Biophysics
Recent CF manuscript: Deshane et al. Free radical-producing myeloid-derived
regulatory cells: potent activators and suppressors of lung inflammation and airway
hyperresponsiveness. Mucosal Immunol, 2011, In Press.
Shalev*
Anath
Medicine
Endocrinology, Diabetes,
& Metabolism
Joint project to test role of CFTR during insulin release and TXNIP expression
Sorscher*
Eric
Medicine
Hematology & Oncology
UAB CF Research Center Director
Stalvey*
Michael
Medicine
Pediatric Pulmonary
Active CF Grant (NIH NIDDK PA-10-059; The Effects of CFTR Deficiency on
Metabolic Bone Disease)
Steele*
Chad
Medicine
Pulmonary, Allergy,
Critical Care
Recent CF manuscript: Steele et al. Vitamin D3 attenuates Th2 responses to
Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with
allergic bronchopulmonary aspergillosis. J Clin Invest 120:3242-54, 2010.
Sztul
Elizabeth
Joint Health
Sciences
Cell Biology
Recent CF manuscript: Fu and Sztul. ER-associated complexes (ERACs) containing
aggregated CFTR are degraded by autophagy. Eur J Cell Biol 88:215-226, 2009
TurnerHenson
Anne
Nursing
Community Health
Outcomes & Systems
Provides training in care of CF and other ‘at risk’ populations for the School of Nursing
Last Name
First Name
School
Dept/Division
Example of Recent Role in CFRC
Velu
Sadanandan
Arts &
Sciences
Chemistry
Synthesis of CFTR activators for preclinical analysis
Vogtle
Laura
Health
Professions
Occupational Therapy
CFRC funded project (Challenges for adolescents with cystic fibrosis – the transition
to adult care providers)
Watts
Ray
Medicine
Dean
CFRC Internal Advisory Committee
Waugh
Jonathan
Health
Professions
Respiratory Therapy
Program
Mentoring of doctoral students in CF related science
Woodworth*
Brad
Medicine
Surgery - Otolaryngology
Active CF Grant (NIH NHLBI K08HL107142; Chloride secretagogues for acquired
CFTR deficiency in chronic rhinosinusitis)
Wooldridge
Nancy
Medicine
Pediatrics - Pulmonary
Active CF grant (DHHS MCH 6T72MC00001-20-02 Pediatric Pulmonary Center)
Wright
Rex
Arts &
Sciences
Psychology
CFRC-funded project to study self-regulatory behavior
Yoder*
Brad
Joint Health
Sciences
Cell Biology
Recent CF Abstract: Havasi et al. Development of a CFTR deficient ciliopathic mouse
model. Ped Pul Supp 33: A215, 2010
* Formally designated as NIH P30 scientific “Research Base.”
The CFRC currently has 71 active members from 8 Schools and more than 30 departments/academic units. CF faculty are specifically designated ‘active’ by
virtue of extant CF funding, recent peer reviewed cystic fibrosis publications, or ongoing professional activities highly relevant to the disease during the past three
years.