2012 Genetics Society Committee and Executive subCommittee Nominees Area A (Gene structure, function and regulation) Colum Walsh Centre for Molecular Biosciences, Tel: +44 (0)28 7012 4484 School of Biomedical Sciences Email: cp.walsh@ulster.ac.uk University of Ulster, Coleraine BT51 3PH http://biomed.science.ulster.ac.uk/stemcell/ Research interests: We are interested in DNA methylation and how it acts to regulate gene activity, as well as its interplay with chromatin modifications. To this end we use mouse and human cell lines and tissues to examine methylation reprogramming during development, both in the germline and the soma. We also look at aberrant methylation in cancer. Unprogrammed loss of methylation also triggers the DNA damage response and we are investigating the mechanisms by which this occurs. Area E (Evolutionary, ecological and population genetics) Judith Mank Dept of Genetics, Evolution and Environment Tel: +44 (0) 1865 281 312 University College London Email: Judith.Mank@zoo.ox.ac.uk Gower Street London WC1E 6BT http://www.zoo.ox.ac.uk/group/jmank/ Research interests: My research interests are at the intersection of the genome, complex animal phenotypes and selection. In particular, I am interested in the ways that sex-specific selection pressures act on the genome to produce separate female and male phenotypes. To address these questions, my group applies models of gene expression and sequence evolution to next-generation transcriptome sequence data to identify genes that have responded to sex-specific selection and are involved in phenotypic dimorphisms. Area F (Corporate genetics and biotechnology) Dominique Kleyn, Non Executive Director BioIndustry Association www.bioindustry.co.uk Tel: 07768 344346 Email: dominique.kleyn@btinternet.com Research interests: I am interested in using the links between genes and disease to discover drugs, develop treatments and diagnose patients. My background is in technology commercialisation, product and business development, most recently as non-executive director and then Chief Executive of London Genetics Limited (2005 – 2011). LGL is a university-backed spin-out providing pharmacogenetic services to support clinical development and more personalised medicines (www.londongenetics.com). Prior to this I worked in technology transfer at Imperial Innovations and in licensing at the Wellcome Foundation plc. I am currently a nonexecutive director at the BioIndustry Association. Vice President, Corporate Affairs Rebecca Oakey Tel: +44 (0)20 718 83711 Dept of Medical & Molecular Genetics Email: rebecca.oakey@kcl.ac.uk 8th Floor Tower Wing King’s College London London SE1 9RT http://www.kcl.ac.uk/medicine/research/divisions/gmm/sections/clusters/bse/oakey/in dex.aspx Research interests: My laboratory is interested in epigenetic regulation of gene expression. Our focus is on a group of imprinted retrogenes, understanding how they are regulated and what role DNA methylation plays in processes such as alternative polyadenylation. We extend this interest into comparative studies in human and apply this to genome-wide methylation analysis of human diseases and bioinformatics tool development. Vice President Elizabeth Fisher Tel: +44 (0) 203 448 4439 Department of Neurodegenerative Disease Email: e.fisher@prion.ucl.ac.uk UCL Institute of Neurology Queen Square London WC1N 3BG http://www.ucl.ac.uk/neuroscience/researchers/show.php?UPI=EMCFI97 Research interests: We are interested in developing novel methods to create new mouse models of neurological disease and working with existing resources such as the ENU archives. Our main research efforts lie in producing models to help understand human neurodegeneration arising from the chromosomal disorder Down syndrome, and the autosomal dominant disorder amyotrophic lateral sclerosis. Honorary Secretary Tanya Whitfield Tel: +44 (0) 114 222 2350 MRC Centre for Developmental and Biomedical Genetics Department of Biomedical Science Fax: +44 (0) 114 222 2787 University of Sheffield Email: t.whitfield@sheffield.ac.uk Sheffield S10 2TN http://cdbg.shef.ac.uk/research/whitfield/ Research interests: My group works on the developing vertebrate inner ear. We are interested in the genes that control axial patterning and neurogenesis in the early otic vesicle, development of the semicircular canal system, the control of endolymph production, the role of cilia, formation of otoliths and sensory hair cell ototoxicity. We use the zebrafish embryo as a model system, both to understand normal developmental processes and as a model for human genetic disease. Postgraduate Representative Adam Hargreaves Genes and Development research group Bangor University Brambell building Deiniol Road Bangor LL57 2UW Tel: +44 (0) 7757 860698 Email: bspa1b@bangor.ac.uk Research interests: Animal skin pigmentation fulfils a variety of functions and is subject to ecological and evolutionary pressures. Snakes are excellent model organisms with which to investigate this area as they demonstrate a diverse variety of pigmentation patterns within and between species whilst all sharing a simple body plan. My research aims to determine the genetic and developmental basis of morphological variation in snakes, using pigmentation patterning as a model system.