PRESS RELEASE August 21, 2013 Leica FluoScoutTM Helps Researchers Get the Most out of their Fluorescence Microscopes Online Tool for Determining the Optimal Fluorescence Filter Cube Set Wetzlar, Germany. On August 21, 2013, Leica Microsystems launched Leica FluoScoutTM, an online tool that enables users of fluorescence microscopes to determine the optimal filter cube or filter set for achieving excellent imaging results. Leica FluoScoutTM is accessed at www.leica- microsystems.com/FluoScout. Find the optimal combination of light sources, fluorophores and filter cubes To achieve excellent results in fluorescence microscopy, the light source, the fluorophores and the filter cubes have to be matched. A perfect fit of excitation and emission filter set maximizes the efficiency of excitation and emission of the fluorophores to provide crisp images. Leica FluoScoutTM makes the matching of these components easy by recommending filter cubes based on the users’ choice of fluorophore. With just one click on the quotation cart users can request offers for selected filter cubes. User-friendly with smart functions Various smart functions make the Leica FluoScoutTM especially user-friendly. The spectrum range is shown as a colored bar to have a constant reference for the visible range of light. To obtain a better overview, the user can fade in and out of single spectra, or zoom to see more details. The transmission and emission can also be quantified. To get started, the online help function and a tooltip guide the user through the site. The selected spectra can either be shared via e-mail or bookmarked using the link creator. Using the contact button, users can post questions directly to Leica Microsystems’ support team. Anja Schué · T +49 (0)6441 / 29 - 2201 · F +49 (0)6441 / 29 - 2527 · corporate.communications@leica-microsystems.com Leica Microsystems GmbH · Ernst-Leitz-Straße 17–37 · D-35578 Wetzlar · www.leica-microsystems.com 1/3 PRESS RELEASE The principle of fluorescence microscopy Fluorescence microscopy harnesses the ability of fluorochromes to emit light after excitation with light of specific wavelengths. Using optical filters, often assembled in a filter cube, the labeled specimen can be visualized on a dark background with the highest sensitivity. First in fluorescence Fluorescence microscopy has long been established as an important analytical tool for bio-medical research disciplines. As a pioneer in this field, Leica Microsystems is dedicated to ongoing intensive research and has constantly contributed innovative products to fluorescence microscopy. Caption: The online tool Leica FluoScoutTM enables users of fluorescence microscopes to determine the best filter cube or filter set for achieving excellent imaging results. _______________ Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company’s history was marked by unparalleled innovation on its way to becoming a global enterprise. 2/3 PRESS RELEASE Its historically close cooperation with the scientific community is the key to Leica Microsystems’ tradition of innovation, which draws on users’ ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: the Life Science Division, Industry Division and Medical Division. The company is represented in over 100 countries with 6 manufacturing facilities in 5 countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany. 3/3