CURRICULUM VITAE
CURRICULUM VITAE
David J. Hunter
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PERSONAL DETAILS
Name:
David John Hunter
Professional Address:
Rheumatology Department, Admin 7C
Royal North Shore Hospital
Pacific Highway, St Leonards
NSW 2065 Australia
Phone:
61 2 9463 1887
Fax:
61 2 9463 1077
Email:
David.Hunter@sydney.edu.au
Born:
17 June 1968
Whangarei, New Zealand.
Citizenship:
Australian
Passport:
Australia and New Zealand
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Summary Statement
Professor Hunter is a rheumatology clinician researcher whose main research focus has been clinical and
translational research in osteoarthritis (OA). He is the Florance and Cope Chair of Rheumatology, Professor
of Medicine at University of Sydney, and Staff Specialist at Royal North Shore Hospital and North Sydney
Orthopaedic and Sports Medicine Centre. A native of New Zealand and an Australian citizen, he earned his
Bachelor of Medicine, Bachelor of Surgery, and Master of Sports Medicine at the University of New South
Wales. He completed a fellowship in Rheumatology at the Royal Australian College of Physicians, and
earned a Masters of Medical Science (Clinical Epidemiology) from the University of Newcastle. He
established a full-time career in medical research in 1999, received his PhD in 2001 and then maintained an
academic faculty appointment in Boston University amongst the foremost OA clinical researchers. He
returned to Australia in 2010. His research is focused on a number of key elements in OA including (but
not limited to) the epidemiology of osteoarthritis, the application of imaging to better understand structure
and function with application to both epidemiologic research and clinical trials, novel therapies in disease
management and heath service system delivery of chronic disease management.
Dr Hunter has over 250 peer reviewed publications in international journals and recently completed his
second book on self management strategies for the lay public.
He has received funding from NHMRC, ARC, NIH, Arthritis Foundation and the American College of
Rheumatology. He has been awarded the Young Investigator of the Year Award by the Osteoarthritis
Research Society International (OARSI). He is an advisory editor for Arthritis Care and Research, an
associate editor of Osteoarthritis and Cartilage (leading orthopedics and osteoarthritis journal), an associate
editor for BMC Musculoskeletal Disorders and is a regular reviewer for all of the major rheumatology
journals, and has been involved in reviewing grants for the NIH, ACR and Arthritis Foundation. He
founded the Osteoarthritis Imaging Working Group (OARSI), co-founded and chairs the annual OA
Imaging Workshop and is part of the OARSI treatment guidelines working group.
He is a member of the Australian College of Physicians, Australian Rheumatology Association, American
College of Rheumatology, and International Osteoarthritis Research Society.
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Education
Undergraduate degree
Bachelor of Medicine, Bachelor of Surgery (Honours Class 2, Division 2)
1987 - 1991: University of New South Wales, Sydney, Australia.
Postgraduate qualifications
1. Fellow of Royal Australasian College of Physicians, Specialty Rheumatology- Awarded 12/99.
Sydney, Australia.
2. Master of Sports Medicine (University of New South Wales, Sydney, Australia), 1999-2002.
3. Masters of Medical Science (Clinical Epidemiology), University of Newcastle, Newcastle, Australia,
2002.
4. Doctor of Philosophy (University of Sydney, Sydney, Australia), 1999-2002. Title “Genetics of
Osteoarthritis”
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Employment History
Current appointments
3/2013-Current
Florance and Cope Chair of Rheumatology
1/2010- Current
Professor of Medicine at University of Sydney
ARC Future Fellow, Kolling Institute and Northern Clinical School
Staff Specialist, Royal North Shore Hospital
04/2009-Current
Associate Professor of Medicine, Tufts University
1/2010- Current
Consultant Rheumatologist, North Sydney Orthopaedic and Sports Medicine
Prior appointments

INTERN, 1/ 1992- 12/1992 Prince of Wales/ Prince Henry Hospitals

RESIDENT MEDICAL OFFICER, 1/ 1993- 12/ 1993 Royal North Shore Hospital

BASIC PHYSICIAN TRAINEE YEAR 1-3, 1/ 1994-12/ 96 Royal North Shore Hospital

SPECIALTY/ ADVANCED TRAINING IN RHEUMATOLOGY
Year 1:
Concord Hospital, 1/ 1997- 12/1997.
Year 2:
Royal North Shore Hospital, 1/ 1998- 12/ 1998.
Year 3:
Twin Research & Genetic Epidemiology Unit, St Thomas’ Hospital, 1/ 1999- 12/ 1999.
Clinical Epidemiology Course- Manchester University

Clinical Associate and Clinical Research Fellow at Rheumatology Department, Royal North Shore
Hospital 1/ 2000- 08/ 2002.

Consultant Rheumatologist, North Sydney Orthopaedic and Sports Medicine, 1/ 2000-08/ 2002.

Assistant to the Associate Dean, Northern Clinical School, 1/ 2001-3/ 2002.

Coordinator Graduate Medical Program Years 1 & 2, Northern Clinical School, 10/ 2000-3/ 2002.

08/ 2002- 10/2009 Assistant Professor of Medicine, Clinical Epidemiology and Research Training
Unit, Department of Medicine, Boston University.; secondary appointment in Rheumatology

06/2007-12/2009
Chief, Division of Research, New England Baptist Hospital
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Licences/ Certification
Fellow of Royal Australasian College of Physicians, Specialty Rheumatology
Medical Board Registration MED0001158448 (AHPRA)
Educational Commission for Foreign Medical Graduates Certificate 06388516
NIH Human Subject Protection Certification Course in the protection human subjects curriculum
completion #1498306
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Professional affiliations

Member of the Australasian College of Physicians

Member of the Australian Rheumatology Association

Member of American College of Rheumatology

Member of International Osteoarthritis Research Society (OARSI)

Board Member OARSI (2007-2013)
Editorial Board
Arthritis and Rheumatism (2006-2009)
Arthritis Care and Research (2010-current)
Osteoarthritis and Cartilage (2009-current)
BMC Musculoskeletal Disorders (2009-current)
International Journal of Rheumatic Diseases (2013-current)
The Open Arthritis Journal
Ad Hoc Reviewer for Journal
Arthritis and Rheumatism, Arthritis Care and Research, Osteoarthritis and Cartilage, Journal of
Rheumatology, Rheumatology, Seminars of Arthritis and Rheumatism, Annals of Rheumatic Diseases
Clinical Journal of Sports Medicine, Journal of American Geriatrics Society
Medical Science Monitor, Nature Reviews Drug Discovery
JAMA, Annals of Internal Medicine, BMJ
American College of Rheumatology Annual Meeting Osteoarthritis Panel
Osteoarthritis Research Society Annual Meeting Review Panel
Editorial Consultant
Physicians' Information and Education Resource (PIER) published by the American College of Physicians
(ACP). (2006-2010)
Reviewer for Grant Assessment
Arthritis Foundation of Australia
National Health and Medical Research Council- Program Grant Review Panel (2010-2013) and ad hoc
project grant
Northern Sydney Area Grants
American College of Rheumatology- REF Awards (2006-2009)
Arthritis Foundation (2006- 2009)
Dutch Arthritis Foundation
National Institutes of Health-
BMIO Study Section- Member (2006-2009)
MCRC P60 Grant review Study Section- 2006
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Education/ Teaching Experience

2002-2009.
Curriculum planning committee- RESCU-Resident teaching for excellence in clinical skills- regular
participant for teaching clinical skills for residents
Evidence based Medicine
Regular monthly lectures on evidence based medicine for residents as part of morning report. This involves
developing skills in evidence based medicine in particular critical appraisal.
Evidence based medicine lecture and tutorial series for 3rd year medical students.
Initiated regular monthly evidence based medicine lecture and tutorial series for rheumatology fellows.
Musculoskeletal Medicine
Initiated monthly lectures on musculoskeletal medicine to rheumatology fellows.
Initiated monthly bedside physical examination skills session with rheumatology fellows.
Coordinator and presenter of musculoskeletal medicine lecture series for primary care residents.
Invited lecturer for annual primary care workshop
Annual Biology of Disease lecture series for rheumatology teaching for medical students
Annual Geriatric Summer Workshop- Invited lecturer
Highlights of Past Teaching/ Training Experience

2001-2002
Coordinator Graduate Medical Program (GMP) 1 and GMP 2, Northern Clinical School, University of
Sydney
Assistant to Associate Dean, Northern Clinical School

2000-
Modules Task Group, RACP Review of Training and Assessment
Regular GMP 1 Communications Group, and GMP 3 PBL Group

1998-
Chairman of Resident Management Committee
Member of Clinical Training Committee
Conducted evaluation of Rheumatology Education entitled “Assessment of
Rheumatological Education of Final Year Medical Undergraduate Students”, D Hunter, L Schrieber, G
Hendry, R Laurent, L March, P Sambrook. Awarded best clinical presentation-NSW ARA Meeting Nov,
1998. Published in APLAR Journal of Rheumatology. 2000; 3(3): 237-241.

1997. Convenor of Musculoskeletal Medicine Lecture Series at Concord Hospital
Voted best teaching registrar by TEATCH study at Concord Hospital
Current (2010-current)
Tutor for EBM
Responsible for osteoarthritis lectures and PBL in Block 2
Ad hoc examiner and teacher when asked
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Mentoring/ supervision of graduate students
CompletedGrace Lo-MSc School of Public Health, Boston University, Graduated May 2006.
Jingbo Niu- Doctorate in Epidemiology, School of Public Health, Boston University, Graduated May 2006.
K. Douglas Gross- Doctorate in Rehabilitation Sciences, Sargent College, Boston University, Graduated
May 2006.
Martin Englund- MSc School of Public Health, Boston University, Graduated August 2007.
William Harvey- MSc School of Public Health, Boston University, Graduated August 2008.
Bart Wise- MSc School of Public Health, Boston University, Graduated August 2008.
Verena Stein (MD)- Postdoctoral fellow (2008-2010)
Leonid Kalichman (PT, PhD)- Postdoctoral PT. (2006-2010)
Will Harvey (MD)- Postdoctoral fellow (2008-2010)
CurrentPradeep Suri (MD)-Postdoctoral fellow (Degenerative disease of the lumbar spine), MSc Harvard University
(2008-Current)
Victoria Johnson- Master of Philosophy candidate (The role of ACL tears in the development of incident
OA), University of Sydney (2011-Current)
Jillian Eyles-Masters of Philosophy candidate (Development of a Clinical Prediction Rule to identify
individuals with knee or hip osteoarthritis likely to experience reduced pain and improved level of function
in response to a non-surgical chronic disease rehabilitation program), University of Sydney (2012-current)
Edward Riordan- Master of Philosophy candidate (Does ACL reconstruction protect against further
structural damage? The KANON trial.), University of Sydney (2012-Current)
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Peer reviewed publications
1. Cheung TC, Hunter D, Bellamy N, Brooks P, March L, Sambrook P. Corticosteroids, Osteoporosis
and the Australian Rheumatologist. APLAR Journal of Rheumatology. 1999, 3: 326-330.
2. Schrieber L, Hendry GD, Hunter D. Musculoskeletal examination teaching in rheumatoid arthritis
education: Trained patient educators compared to nonspecialist doctors. Journal of Rheumatology. 2000;
27(6): 1531-1532.
3. Naganathan V, March L, Hunter D, Pocock NA, Markovey J, Sambrook PN. Quantitative heel
ultrasound as a predictor for osteoporosis. MJA. 1999; 171: 297-300.
4. Hunter D, Schrieber L, Hendry G, Laurent R, March L, Sambrook PN. Assessment of Rheumatological
Education of Final Year Medical Undergraduate Students. APLAR Journal of Rheumatology. 2000; 3(3):
237-241.
5. Hunter D, de Lange M, Snieder H, MacGregor AJ, Swaminathan R, Thakker RV, Spector TD. Genetic
Contribution to Bone Metabolism, Calcium Excretion, and Vitamin D and Parathyroid Hormone
Regulation. J Bone Min Research. 2001;16:371-378.
6. Hunter D, Major P, Arden N, Swaminathan R, Andrew T, Keen R, Snieder H, Spector TD. A
Randomized Controlled Trial of Vitamin D Supplementation on Preventing Postmenopausal Bone
Loss and Modifying Bone Metabolism Using Identical Twin Pairs. Journal of Bone Min Res. 2000; 15(11):
2276-2283.
7. Hunter DJ. Sambrook PN. Bone loss: Epidemiology of bone loss. Arthritis Research. 2(6):441-445, 2000.
(Review Article)
8. Hunter D, de Lange M, Andrew T, Snieder H, MacGregor AJ, Spector TD. Genetic Variation in Bone
Mineral Density (BMD) and Calcaneal Ultrasound: A Study of the Influence of Menopause using
Female Twins. Osteoporosis International. 12(5):406-11, 2001.
9. Sambrook PN, Raj A, Hunter D, Naganathan V, Mason R, Robinson B, Osteoporosis with low dose
corticosteroids: contribution of underlying disease effects and discriminatory ability of ultrasound
versus bone densitometry. Journal of Rheumatology. 28(5):1063-7, 2001 May.
10. Hunter D, de Lange M, Snieder H, MacGregor AJ, Swaminathan R, Thakker RV, Spector TD. Genetic
Contribution to Renal Function and Electrolyte Balance: A Twin Study. Clinical Science. 103(3): 259-265;
2002.
11. Hunter DJ, March L, Sambrook PN. Knee Osteoarthritis: The Influence of Environmental Factors.
Clinical and Experimental Rheumatology. 2002: 20 (1); 93-100. (Review)
12. Hunter DJ, Spector TD. The role of bone metabolism in osteoarthritis. Current Rheumatology Reports. 5(1):
15-19; 2003.
13. Hunter DJ, Snieder H, March L, Sambrook PN. Genetic contribution to cartilage volume in women: a
classical twin study. Rheumatology 2003; 42(12):1495-1500.
14. Hunter DJ, Hart D, Snieder H, Bettica P, Swaminathan R, Spector TD. Evidence of altered bone
turnover, vitamin D and calcium regulation with knee osteoarthritis in female twins. Rheumatology 2003;
42(11):1311-1316.
15. Hunter DJ, March L, Sambrook PN. The association of cartilage volume with knee pain. Osteoarthritis &
Cartilage 2003; 11(10):725-729.
16. Zhang Y, Hunter DJ, Nevitt MC, Xu L, Niu J, Lui LY et al. Association of squatting with increased
prevalence of radiographic tibiofemoral knee osteoarthritis: the Beijing Osteoarthritis Study. Arthritis &
Rheumatism 2004; 50(4):1187-1192.
17. Hunter DJ, et al. Chopstick arthropathy: The Beijing Osteoarthritis Study. Arthritis & Rheumatism 2004;
50(5):1495-1500.
18. Hunter DJ, Felson DT. Therapeutic knee taping improved pain and disability in osteoarthritis of the
knee. (Commentary) Evidence-Based Medicine 2004; 9:18.
19. Hunter DJ. Review: evidence exists for 33 different treatment options for osteoarthritis of the knee.
(Commentary) Evidence-Based Medicine 2004; 9:81.
20. Hunter DJ, Allaire S. Combination disease-modifying antirheumatic drug therapy reduced work
disability in early rheumatoid arthritis. (Commentary) ACP J Club. 2004 Nov-Dec;141(3):69.
21. Felson DT, Goggins J, Niu J, Zhang Y, Hunter DJ. The effect of body weight on progression of knee
osteoarthritis is dependent on alignment. Arthritis and Rheumatism 2004; 50(12): 3904-3909.
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22. Hunter DJ. Demissie S. Cupples LA. Aliabadi P. Felson DT. A genome scan for joint-specific hand
osteoarthritis susceptibility: The Framingham Study. Arthritis & Rheumatism. 50(8):2489-96, 2004 Aug.
23. Hunter DJ, et al. Knee height, knee pain and knee osteoarthritis. The Beijing Osteoarthritis Study.
Arthritis and Rheumatism. 52(5):1418-23, 2005 May.
24. Hunter DJ, et al. Structural factors associated with malalignment in knee osteoarthritis: The Boston
Osteoarthritis Knee Study. J Rheumatology 2005 Nov;32(11):2192-9.
25. Hunter DJ, et al. Trapeziometacarpal subluxation predisposes to incident trapeziometacarpal
Osteoarthritis (OA): The Framingham Study. Osteoarthritis and Cartilage 2005, 13; 953-57.
26. Felson DT. Gale DR. Elon Gale M. Niu J. Hunter DJ. Goggins J. Lavalley MP. Osteophytes and
progression of knee osteoarthritis. Rheumatology. 44(1):100-4, 2005 Jan.
27. Lo GH. Hunter DJ. et al. Bone marrow lesions in the knee are associated with increased local bone
density. Arthritis & Rheumatism. 52(9):2814-21, 2005 Sep.
28. Amin S. LaValley MP. Guermazi A. Grigoryan M. Hunter DJ. Clancy M. Niu J. Gale DR. Felson DT.
The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in
men and women with knee osteoarthritis. Arthritis & Rheumatism. 52(10):3152-9, 2005 Oct.
29. Neogi T, Hunter DJ, et al. Frequency and predictors of inappropriate management of recurrent gout
attacks in a longitudinal study. J Rheumatology. 2006 Jan;33(1):104-9.
30. Hunter DJ, Conaghan PG. Imaging outcomes and their role in determining outcomes in OA and RA.
(Review) Current Opinion in Rheumatology. 2006; 18: 157-162.
31. Hunter DJ, Felson DT. Osteoarthritis. (Review) BMJ.2006; 332: 639-642.
32. Hunter DJ, et al. The Association of Meniscal Pathologic Changes With Cartilage Loss in Symptomatic
Knee Osteoarthritis. Arthritis & Rheumatism. 54(3): 795-801, 2006 March.
33. York M, Hunter DJ. Initial combination therapy with prednisone or infliximab improved outcomes in
early rheumatoid arthritis more than DMARDs alone. (Commentary) ACP J Club. 2006 MayJun;144(3):72.
34. Hunter DJ, Conaghan PG, Peterfy CG, Bloch D, Guermazi A, Woodworth T, Stevens R, Genant HK.
Responsiveness, effect size, and smallest detectable difference of Magnetic Resonance Imaging in knee
osteoarthritis. Osteoarthritis Cartilage. 2006;14 Suppl 1:112-5.;
35. Hunter DJ, Zhang Y, Niu J, Goggins J, Amin S, Lavalley MP, Guermazi A, Genant H, Gale D, Felson
DT. Increase in bone marrow lesions associated with cartilage loss: A longitudinal magnetic resonance
imaging study of knee osteoarthritis. Arthritis Rheum. 2006 May;54(5):1529-35.
36. Hunter DJ, Zhang Y, Tu X, LaValley MP, Niu J, Amin S, Guermazi A, Genant H, Gale D, Felson DT.
Change in Joint Space Width: hyaline articular cartilage loss or alteration in meniscus? Arthritis and
Rheumatism. 2006 Aug;54(8):2488-95.
37. Conaghan PG, Tennant A, Peterfy CG, Woodworth T, Stevens R, Guermazi A, Genant H, Felson DT,
Hunter D. Examining a whole-organ magnetic resonance imaging scoring system for osteoarthritis of
the knee using Rasch analysis. Osteoarthritis Cartilage. 2006;14 Suppl 1:116-21.
38. Sengupta M, Zhang YQ, Niu JB, Guermazi A, Grigorian M, Gale D, Felson DT, Hunter DJ. High
signal in knee osteophytes is not associated with knee pain. Osteoarthritis Cartilage. 2006 May;14(5):413-7.
39. Neogi T, Nevitt M, Niu J, LaValley MP, Hunter DJ, et al. Lack of association between
chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: Results of two
prospective longitudinal magnetic resonance imaging studies. Arthritis Rheum. 2006 May;54(6):1822-28.
40. Hunter DJ, Pollo FE. Biomechanics and Knee Osteoarthritis. (Review) Current Rheumatology Reviews.
2006 May; 2 (2): 123-129.
41. Hunter DJ, York M, Chaisson CE, Woods R, Niu J, Zhang Y. Recent diuretic use and the risk of
recurrent gout attacks: the online case-crossover gout study. J Rheumatology. 2006 Jul;33(7):1341-5.
42. Bauer DC, Hunter DJ, Abramson SB, Attur M, Corr M, Felson D, Heinegard D, Jordan JM, Kepler
TB, Lane NE, Saxne T, Tyree B, Kraus VB, For The Osteoarthritis Biomarkers Network. Classification
of osteoarthritis biomarkers: a proposed approach. Osteoarthritis Cartilage. 14(8):723-7, 2006 Aug.
43. Lo. GH, Zhang Y, McLennan C, Niu J, Kiel DP, McLean RR, Aliabadi P, Felson DT, Hunter DJ. The
ratio of medial to lateral tibial plateau bone mineral density and compartment-specific tibiofemoral
osteoarthritis. Osteoarthritis and Cartilage. 2006; 14: 984-990.
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44. Zhang Y. Woods R. Chaisson CE. Neogi T. Niu J. McAlindon TE. Hunter D. Alcohol consumption as
a trigger of recurrent gout attacks. American Journal of Medicine. 119(9):800.e13-8, 2006 Sep.
45. Zhai G, Aviv A, Hunter DJ, et al. Reduction of leucocyte telomere length in radiographic hand
osteoarthritis: a population-based study. Ann Rheum Dis, November 1, 2006; 65(11): 1444 - 1448.
46. Gross KD, Hunter DJ. Osteoarthritis of the Knee (Review). Geriatrics and Aging. September 2006; 9 (8):
526-534.
47. Zhang Y. Neogi T. Hunter D. Reply to letter by Choi. American Journal of Medicine. 2007; 120 (10):e7.
48. Zhang Y, Chaisson CE, McAlindon T, Woods R, Hunter DJ, et al. The online case-crossover study is a
novel approach to study triggers for recurrent disease flares. Journal of Clinical Epidemiology 60 (2007); 5055
49. Livshits G, Kato BS, Zhai G, Hart DJ, Hunter D, et al. Genomewide Linkage Scan of Hand
Osteoarthritis in Female Twin Pairs Showing Replication of QTLs on Chromosome 2 and 19. Ann
Rheum Dis. 2007 May; 66(5):623-7.
50. Felson DT, Niu JB, Clancy MM, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G,
Booth SL. Low levels of vitamin D and worsening of knee osteoarthritis: Results of two longitudinal
studies. Arthritis and Rheumatism. 2007; 56(1):129-136.
51. Hunter DJ, Lavalley M, Li J, Zhang Y, Bauer D, Nevitt M, Guermazi A, Degroot J, Sakkee N, Gale D,
Felson DT. Urinary pentosidine does not predict cartilage loss among subjects with symptomatic knee
OA: the BOKS Study. Osteoarthritis and Cartilage. 2007 Jan; 15 (1):93-7.
52. Amin S. Niu J. Guermazi A. Grigoryan M. Hunter DJ. Clancy M. LaValley MP. Genant HK. Felson
DT. Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritis.
Annals of the Rheumatic Diseases. 66(1):18-22, 2007 Jan.
53. Baker K, Goggins J, Xie H, Szumowski K, LaValley M, Hunter DJ, Felson DT. A randomized
crossover trial of a wedged insole for treatment of knee osteoarthritis. Arthritis and Rheumatism. 2007;
56(4):1198-1203.
54. Hunter DJ, Niu J, Felson DT, Harvey WF, Gross KD, McCree P, Aliabadi P, Sack B, Zhang Y. Knee
alignment does not predict incident osteoarthritis: The Framingham osteoarthritis study. Arthritis and
Rheumatism. 2007; 56(4):1212-1218.
55. Kalichman L, Hunter DJ. Lumbar Facet Joint Osteoarthritis: A Review. (Review). Seminars in Arthritis
and Rheumatism. 2007 Oct;37(2):69-80.
56. Hunter DJ, Wise B. Review: diacerein is more effective than placebo and is as effective as NSAIDs for
knee and hip osteoarthritis. Evidence-Based Medicine 2007; Jun;12(3):74. (Commentary).
57. Hunter DJ, et al. Patella malalignment, pain and patellofemoral progression: the Health ABC Study.
Osteoarthritis Cartilage. 2007 Oct;15(10):1120-7.
58. Hill CL, Hunter DJ, et al. Synovitis detected on magnetic resonance imaging and its relation to pain and
cartilage loss in knee osteoarthritis. Ann Rheum Dis. 66(12):1599-603, 2007 Dec.
59. Kalichman L, et al. The association between patellar alignment on magnetic resonance imaging and
radiographic manifestations of knee osteoarthritis. Arthritis Res Ther. 2007 Mar 7;9(2):R26
60. Kalichman L. Zhang Y. Niu J. Goggins J. Gale D. Felson DT. Hunter D. The association between
patellar alignment and patellofemoral joint osteoarthritis features--an MRI study. Rheumatology.
46(8):1303-8, 2007 Aug.
61. Kalichman L, Zhu Y, Zhang Y, Niu J, Gale D, Felson DT, Hunter D. The association between patella
alignment and knee pain and function: an MRI study in persons with symptomatic knee osteoarthritis.
Osteoarthritis Cartilage. 2007 Nov;15(11):1235-40.
62. Zhang F, Zhai G, Kato BS, Hart DJ, Hunter D, Spector TD, Ahmadi K. Association between
KLOTHO gene and hand osteoarthritis in a female Caucasian population. Osteoarthritis & Cartilage 2007
June; 15 (6):624-9
63. Hunter DJ. In the clinic. Osteoarthritis. Ann Intern Med. 2007 Aug 7;147(3):ITC8-1-ITC8-16.
64. Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, Bierma-Zeinstra S, Brandt
KD, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P.
OARSI recommendations for the management of hip and knee osteoarthritis, Part I: Critical appraisal
of existing treatment guidelines and systematic review of current research evidence. Osteoarthritis
Cartilage. 2007 Sep;15(9):981-1000.
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65. Lo GH, Niu J, McLennan CE, Kiel DP, McLean RR, Guermazi A, Genant HK, McAlindon TE,
Hunter DJ. Meniscal damage associated with increased local subchondral bone mineral density: a
Framingham study. Osteoarthritis Cartilage. 2007; 16 (2): 261 – 267.
66. Gross KD, Niu J, Zhang YQ, Felson DT, McLennan C, Hannan MT, Holt KG, Hunter DJ. Varus foot
alignment and hip conditions in older adults. Arthritis Rheum. 2007 Sep; 56(9):2993-8.
67. Felson DT, Niu J, McClennan C, Sack B, Aliabadi P, Hunter DJ, Guermazi A, Englund M. Knee
buckling: prevalence, risk factors, and associated limitations in function. Ann Intern Med. 2007 Oct
16;147(8):534-40.
68. Hutchings A, Calloway M, Choy E, Hooper M, Hunter DJ, Jordan JM, Zhang Y, Baser O, Long S,
Palmer L. The Longitudinal Examination of Arthritis Pain (LEAP) Study: Relationships Between
Weekly Fluctuations in Patient-Rated Joint Pain and Other Health Outcomes. J Rheumatol. 2007;
34:2291-300.
69. Eckstein F, Mosher T, Hunter DJ: Imaging of knee osteoarthritis: data beyond the beauty. (Review)
Current Opinion Rheumatol. 19(5):435-443 (2007).
70. Kalichman L, Hunter DJ. Diagnosis and conservative management of degenerative lumbar
spondylolisthesis. Eur Spine J. 2007; 17 (3): 327-335.
71. Englund M, Niu J, Guermazi A, Roemer FW, Hunter DJ, Lynch JA, Lewis CE, Torner J, Nevitt MC,
Zhang YQ, Felson DT. Effect of meniscal damage on the development of frequent knee pain, aching,
or stiffness. Arthritis Rheum. 2007 Nov 29;56(12):4048-4054.
72. Hunter DJ, et al. Cartilage markers and their association with cartilage loss on magnetic resonance
imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study. Arthritis Res Ther. 2007 Oct
24;9(5):R108.
73. Hutchings A, Calloway M, Choy E, Hooper M, Hunter DJ, Jordan JM, Zhang Y, Baser O, Long S,
Palmer L. The Longitudinal Examination of Arthritis Pain (LEAP) study: relationships between weekly
fluctuations in patient-rated joint pain and other health outcomes. J Rheumatol. 2007 Nov;34(11):2291300.
74. Bennell KL, Hunt MA, Wrigley TV, Hunter DJ, Hinman RS. The effects of hip muscle strengthening
on knee load, pain, and function in people with knee osteoarthritis: a protocol for a randomised, singleblind controlled trial. BMC Musculoskelet Disord. 2007 Dec 7; 8:121.
75. Hernandez-Molina G, Neogi T, Hunter DJ, et al. The association of bone attrition with knee pain and
other MRI features of osteoarthritis. Ann Rheum Dis. 2008; 67: 43-47.
76. Hunter DJ, et al. The development and reliability of a new scoring system for knee osteoarthritis MRI:
BLOKS (Boston Leeds Osteoarthritis Knee Score). Ann Rheum Dis. 2008; 67: 206-211.
77. Kim HA. Kim S. Seo YI. Choi HJ. Seong SC. Song YW. Hunter D. Zhang Y. The epidemiology of
total knee replacement in South Korea: national registry data. Rheumatology. 47(1):88-91, 2008 Jan.
78. Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, Bierma-Zeinstra S, Brandt
KD, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P.
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidencebased, expert consensus guidelines. Osteoarthritis Cartilage. 2008 Feb;16(2):137-62.
79. Hellio Le Graverand MP, Vignon EP, Brandt KD, Mazzuca SA, Piperno M, Buck R, Charles HC,
Hunter DJ, Jackson CG, Kraus VB, Link TM, Schnitzer TJ, Vaz A, Wyman B. Head-to-head
comparison of the Lyon schuss and fixed flexion radiographic techniques. Long-term reproducibility in
normal knees and sensitivity to change in osteoarthritic knees. Ann Rheum Dis. 2008; 67:1562-1566.
80. Harvey WF, Niu J, Zhang Y, McCree PI, Felson DT, Nevitt MC, Xu L, Aliabadi P, Hunter DJ. Knee
alignment differences between Chinese and Caucasians subjects without osteoarthritis. Ann Rheum Dis.
2008; 67:1524-1528.
81. Hunter DJ, Niu J, Zhang Y, Lavalley M, McClennan CE, Hudelmaier M, Eckstein F, Felson DT.
Premorbid knee OA is not characterized by diffuse thinness: The Framingham Study. Ann Rheum Dis.
2008 Jan 24; [Epub ahead of print].
82. Amin S, Guermazi A, Lavalley MP, Niu J, Clancy M, Hunter DJ, Grigoryan M, Felson DT. Complete
anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and
women with knee osteoarthritis. Osteoarthritis Cartilage. 2008 Aug; 16(7): 897-902.
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83. Eckstein F, Buck RJ, Burstein D, Charles HC, Crim J, Hudelmaier M, Hunter D, Hutchins G, Jackson
C, Byers Kraus V, Lane NE, Link TM, Majumdar S, Mazzuca S, Prasad PV, Schnitzer TJ, Taljanovic
MS, Vaz A, Wyman B, Hellio Le Graverand MP. Precision of 3.0 Tesla Quantitative Magnetic
Resonance Imaging of cartilage morphology in a multi center clinical trial. Ann Rheum Dis. 2008;
67(12):1683-8.
84. Reichenbach S, Guermazi A, Niu J, Neogi T, Hunter DJ, Roemer FW, McLennan CE, HernandezMolina G, Felson DT. Prevalence of bone attrition on knee radiographs and MRI in a communitybased cohort. Osteoarthritis Cartilage. 2008; 16(9):1005-10.
85. Hunter, D. Intraarticular hylan was no better than hyaluronic acids for osteoarthritis of the knee.
(Commentary) ACP J Club. 2008 Mar-Apr;148(2):42.
86. Kalichman L, Hunter DJ. The genetics of intervertebral disc degeneration. Familial predisposition and
heritability estimation. (Review) Joint Bone Spine. 2008; 75(4):383-7.
87. Hunter DJ, Niu J, Zhang Y, Totterman S, Tamez J, Dabrowski C, Davies R, Hellio Le Graverand MP,
Luchi M, Tymofyeyev Y, Beals CR. Change in cartilage morphometry: a sample of the progression
cohort of the Osteoarthritis Initiative. Ann Rheum Dis. 2008 Apr 13. [Epub ahead of print]
88. Kalichman L, Hunter DJ. The genetics of intervertebral disc degeneration. Associated genes. (Review)
Joint Bone Spine. 2008; 75 (4): 388-396.
89. Hunter DJ. Are there promising biologic therapies for osteoarthritis? (Review) Curr Rheumatol Rep. 2008
Jan;10(1):19-25.
90. Mazzuca SA, Hellio Le Graverand MP, Vignon E, Hunter DJ, Jackson CG, Kraus VB, Link TM,
Schnitzer TJ, Vaz A, Charles HC. Performance of a non-fluoroscopically assisted substitute for the
Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space
narrowing in osteoarthritic knees. Osteoarthritis Cartilage. 2008; 16(12):1555-9.
91. Kim HA, Koh SH, Lee B, Kim IJ, Seo YI, Song YW, Hunter DJ, Zhang Y. Low rate of total hip
replacement as reflected by a low prevalence of hip osteoarthritis in South Korea. Osteoarthritis Cartilage.
2008; 16 (12): 1572- 1575.
92. Marra MD, Crema MD, Chung M, Roemer FW, Hunter DJ, Zaim S, Diaz L, Guermazi A. MRI
features of cystic lesions around the knee. Knee. 2008;15 (6): 423 - 438.
93. Amin S, Goggins J, Niu J, Guermazi A, Grigoryan M, Hunter DJ, Genant HK, Felson DT.
Occupation-Related Squatting, Kneeling, and Heavy Lifting and the Knee Joint: A Magnetic Resonance
Imaging-Based Study in Men. J Rheumatol. 2008; 35 (8): 1645-1649.
94. Hunter DJ. Preface. Osteoarthritis. Rheumatic Disease Clinics of North America. August 2008; 34 (3): xiii-xvi.
95. Hunter DJ, McDougall JJ, Keefe FJ. The Symptoms of Osteoarthritis and the Genesis of Pain (Review).
Rheumatic Disease Clinics of North America. August 2008; 34 (3): 623-643.
96. Hunter DJ, Lo GH. The Management of Osteoarthritis: An Overview and Call to Appropriate
Conservative Treatment (Review). Rheumatic Disease Clinics of North America. August 2008; 34 (3): 689-712.
97. Harvey WF, Hunter DJ. The Role of Analgesics and Intra-articular Injections in Disease Management
(Review). Rheumatic Disease Clinics of North America. August 2008; 34 (3): 777-788.
98. Hunter DJ, Hellio Le Graverand-Gastineau MP. How Close are We to Having Structure-Modifying
Drugs Available? (Review) Rheumatic Disease Clinics of North America. August 2008; 34 (3): 789-802.
99. Hunter DJ, Lavalley M, Li J, Bauer DC, Nevitt M, Degroot J, Poole R, Eyre D, Guermazi A, Gale D,
Totterman S, Felson DT. Biochemical markers of bone turnover and their association with bone
marrow lesions. Arthritis Res Ther. 2008 Aug 29;10(4):R102. [Epub ahead of print]
100.Bennell KL, Creaby MW, Wrigley TV, Hunter DJ. Tibial subchondral trabecular volumetric bone
density in medial knee joint osteoarthritis using peripheral quantitative computed tomography
technology. Arthritis Rheum. 2008 Aug 29;58(9):2776-2785. [Epub ahead of print].
101.Englund M, Guermazi A, Gale D, Hunter DJ, Aliabadi P, Clancy M, Felson DT. Incidental meniscal
findings on knee MRI in middle-aged and elderly persons. N Engl J Med. 2008 Sep 11;359(11):1108-15.
102.Kalichman L, Li L, Kim DH, Guermazi A, Berkin V, O'Donnell CJ, Hoffmann U, Cole R, Hunter DJ.
Facet Joint Osteoarthritis and Low Back Pain in the Community-Based Population. Spine. 2008 Oct 14.
[Epub ahead of print]
103.Hunter DJ. Advanced imaging in osteoarthritis. (Review) Bull NYU Hosp Jt Dis. 2008;66(3):251-60.
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104.Roemer FW, Hunter DJ, Guermazi A. MRI-based semiquantitative assessment of subchondral bone
marrow lesions in osteoarthritis research. Osteoarthritis Cartilage. 2008 Oct 21. [Epub ahead of print]
105.Roemer FW, Guermazi A, Hunter DJ, Niu J, Zhang Y, Englund M, Javaid MK, Lynch JA, Mohr A,
Torner J, Lewis CE, Nevitt MC, Felson DT. The association of meniscal damage with joint effusion in
persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies.
Osteoarthritis Cartilage. 2008 Oct 17. [Epub ahead of print].
106.Katz LM, Battaglia TC, Patino P, Reichmann W, Hunter DJ, Richmond JC. A retrospective comparison
of the incidence of bacterial infection following anterior cruciate ligament reconstruction with autograft
versus allograft. Arthroscopy. 2008 Dec;24(12):1330-5.
107.Hunter DJ. Preface. Med Clin North Am. 2009 Jan;93(1):xv-xviii.
108.Hunter DJ, McDougall JJ, Keefe FJ. The symptoms of osteoarthritis and the genesis of pain. Med Clin
North Am. 2009 Jan;93(1):83-100.
109.Hunter DJ, Hellio Le Graverand-Gastineau MP. How Close are We to Having Structure-Modifying
Drugs Available? Med Clin North Am. 2009 Jan;93(1):223-34.
110.Harvey WF, Hunter DJ. The role of analgesics and intra-articular injections in disease management. Med
Clin North Am. 2009 Jan;93(1):201-11.
111.Hunter DJ, Lo GH. The management of osteoarthritis: an overview and call to appropriate
conservative treatment. Med Clin North Am. 2009 Jan;93(1):127-43.
112. Fayfman M, Niu J, Zhang YQ, Felson DT, Sack B, Aliabadi P, Selhub J, Hunter DJ. The relation of
plasma homocysteine to radiographic knee osteoarthritis. Osteoarthritis Cartilage. 2008 Nov 30. [Epub
ahead of print]
113.Roemer FW, Hunter DJ, Guermazi A. Semiquantitative assessment of synovitis in osteoarthritis on non
contrast-enhanced MRI. Osteoarthritis Cartilage. 2008 Nov 21. [Epub ahead of print] No abstract available.
114.Neumann G, Hunter D, Nevitt M, Chibnik LB, Kwoh K, Chen H, Harris T, Satterfield S, Duryea J;
For the Health ABC Study. Location specific radiographic joint space width for osteoarthritis
progression. Osteoarthritis Cartilage. 2008 Nov 12.
115.Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M,
Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV,
Schnitzer TJ, Vaz A, Wirth W, Eckstein F. Change in regional cartilage morphology and joint space
width in osteoarthritis participants versus healthy controls - a multicenter study using 3.0 Tesla MRI
and Lyon Schuss radiography. Ann Rheum Dis. 2008 Dec 22. [Epub ahead of print]
116.Lo GH, Hunter DJ, Nevitt M, Lynch J, McAlindon TE; for the OAI Investigators Group. Strong
association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from
the osteoarthritis initiative. Osteoarthritis Cartilage. 2008 Nov 27. [Epub ahead of print]
117.Kalichman L, Kim DH, Li L, Guermazi A, Berkin V, Hunter DJ. Spondylolysis and spondylolisthesis:
prevalence and association with low back pain in the adult community-based population. Spine. 2009 Jan
15;34(2):199-205.
118.Amin S, Baker K, Niu J, Clancy M, Goggins J, Guermazi A, Grigoryan M, Hunter DJ, Felson DT.
Quadriceps strength and the risk of cartilage loss and symptom progression in knee osteoarthritis.
Arthritis Rheum. 2009 Jan;60(1):189-98.
119.Hunter DJ, Gerstenfeld L, Bishop G, Davis AD, Mason ZD, Einhorn TA, Maciewicz RA, Newham P,
Foster M, Jackson S, Morgan EF. Bone marrow lesions from osteoarthritis knees are characterized by
sclerotic bone that is less well mineralized. Arthritis Res Ther. 2009 Jan 26;11(1):R11. [Epub ahead of print]
120.Reichenbach S, Yang M, Eckstein F, Niu J, Hunter DJ, McLennan CE, Guermazi A, Roemer FW,
Hudelmaier M, Aliabadi P, Felson DT. Do cartilage volume or thickness distinguish knees with and
without mild radiographic osteoarthritis? The Framingham Study. Ann Rheum Dis. 2009 Feb 4. [Epub
ahead of print]
121. Hunter DJ, Eckstein F. Exercise and osteoarthritis (Review). J Anat. 2009 Feb;214(2):197-207.
122. Jette AM, McDonough CM, Haley SM, Ni P, Olarsch S, Latham N, Hambleton RK, Felson D, Kim
YJ, Hunter D. A computer-adaptive disability instrument for lower extremity osteoarthritis research
demonstrated promising breadth, precision, and reliability. J Clin Epidemiol. 2009 Feb 10. [Epub ahead of
print]
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123. Guermazi A, Hunter DJ, Roemer FW. (Review). Plain radiography and magnetic resonance imaging
diagnostics in osteoarthritis: validated staging and scoring. J Bone Joint Surg Am. 2009 Feb;91 Suppl 1:5462.
124. Hunter DJ, Sharma L, Skaife T. (Review). Alignment and osteoarthritis of the knee. J Bone Joint Surg
Am. 2009 Feb;91 Suppl 1:85-9.
125. Ornetti P, Brandt K, Hellio-le Graverand MP, Hochberg M, Hunter DJ, Kloppenburg M, Lane N,
Maillefert JF, Mazzuca SA, Spector T, Utard-Wlerick G, Vignon E, Dougados M. OARSI-OMERACT
definition of relevant radiological progression in hip/knee osteoarthritis. Osteoarthritis Cartilage. 2009 Feb
9. [Epub ahead of print]
126. Burstein D, Hunter DJ. "Why aren't we there yet?" Re-examining standard paradigms in imaging of
OA Summary of the 2nd annual workshop on imaging based measures of osteoarthritis. Osteoarthritis
Cartilage. 2009 Feb 9. [Epub ahead of print]
127.Stamenović D, Kojić M, Stojanović B, Hunter D. Pneumatic osteoarthritis knee brace. J Biomech Eng.
2009 Apr;131(4):045001.
128.Kalichman L, Hunter DJ, Kim DH, Guermazi A. Association between disc degeneration and
degenerative spondylolisthesis? Pilot study. Journal of Back and Musculoskeletal Rehabilitation 2009; 22(1):
21-25.
129.Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M,
Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV,
Schnitzer TJ, Vaz A, Wirth W, Eckstein F. Subregional femorotibial cartilage morphology in women comparison between healthy controls and participants with different grades of radiographic knee
osteoarthritis. Osteoarthritis Cartilage. 2009 Mar 24. [Epub ahead of print]
130.Hunter DJ, Le Graverand MP, Eckstein F. Radiologic markers of osteoarthritis progression. (Review)
Curr Opin Rheumatol. 2009 Mar;21(2):110-7.
131.Roemer FW, Frobell R, Hunter DJ, Crema MD, Fischer W, Bohndorf K, Guermazi A. MRI-detected
subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance,
relevance and radiological differential diagnosis. Osteoarthritis Cartilage. 2009 Mar 31. [Epub ahead of print]
132.Kalichman L, Kim DH, Li L, Guermazi A, Hunter DJ. Facet orientation and tropism: associations with
facet joint osteoarthritis and degenerative spondylolisthesis. Spine 2009. [Epub ahead of print].
133.Kalichman L, Cole R, Kim DH, Li L, Suri P, Guermazi A, Hunter DJ. Spinal stenosis prevalence and
association with symptoms: the Framingham Study. Spine J. 2009 Apr 22. [Epub ahead of print]
134.Hunter DJ, Buck R, Vignon E, Eckstein F, Brandt K, Mazzuca SA, Wyman BT, Otterness I, Hellio Le
Graverand MP. Relation of regional articular cartilage morphometry and meniscal position by MRI to
joint space width in knee radiographs. Osteoarthritis Cartilage. 2009 Apr 17. [Epub ahead of print]
135.Hunter DJ. Risk stratification for knee osteoarthritis progression: a narrative review. Osteoarthritis
Cartilage. 2009 May 3. [Epub ahead of print]
136.Roemer FW, Guermazi A, Zhang Y, Yang M, Hunter DJ, Crema MD, Bohndorf K. Hoffa's Fat Pad:
Evaluation on Unenhanced MR Images as a Measure of Patellofemoral Synovitis in Osteoarthritis. AJR
Am J Roentgenol. 2009 Jun;192(6):1696-700.
137.Hunter DJ. Osteoarthritis: Hyaluronic acid is not effective in symptomatic hip OA. Nat Rev Rheumatol.
2009 Jul;5(7):359-60.
138.Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, Devita P, Lyles M, Eckstein F, Hunter DJ,
Williamson JD, Nicklas BJ. The Intensive Diet and Exercise for Arthritis (IDEA) Trial: design and
rationale. BMC Musculoskelet Disord. 2009 Jul 28;10(1):93.
139.Hunter DJ, Wilson DR. Role of alignment and biomechanics in osteoarthritis and implications for
imaging. Radiol Clin North Am. 2009 Jul;47(4):553-66.
140.Hunter DJ. Insights from imaging on the epidemiology and pathophysiology of osteoarthritis. Radiol
Clin North Am. 2009 Jul;47(4):539-51.
141.Jette AM, McDonough CM, Ni P, Haley SM, Hambleton RK, Olarsch S, Hunter DJ, Kim YJ, Felson
DT. A functional difficulty and functional pain instrument for hip and knee osteoarthritis. Arthritis Res
Ther. 2009 Jul 9;11(4):R107. [Epub ahead of print]
142.Lo GH, McAlindon TE, Niu J, Zhang Y, Beals C, Dabrowski C, Hellio Le Graverand MP, Hunter DJ;
for the OAI Investigators Group. Bone marrow lesions and joint effusion are strongly and
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independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis
initiative. Osteoarthritis Cartilage. 2009 Jun 26. [Epub ahead of print]
143.Richmond J, Hunter D, Irrgang J, Jones MH, Levy B, Marx R, Snyder-Mackler L, Watters WC 3rd,
Haralson RH 3rd, Turkelson CM, Wies JL, Boyer KM, Anderson S, St Andre J, Sluka P, McGowan R.
Treatment of osteoarthritis of the knee (nonarthroplasty). J Am Acad Orthop Surg. 2009 Sep;17(9):591600.
144. Eckstein F, Benichou O, Wirth W, Nelson DR, Maschek S, Hudelmaier M, Kwoh CK, Guermazi A,
Hunter D; Osteoarthritis Initiative Investigators. Magnetic resonance imaging-based cartilage loss in
painful contralateral knees with and without radiographic joint space narrowing: Data from the
osteoarthritis initiative. Arthritis Rheum. 2009 Aug 27;61(9):1218-1225.
145. Eckstein F, Wirth W, Hudelmaier MI, Maschek S, Hitzl W, Wyman BT, Nevitt M, Hellio Le
Graverand MP, Hunter D; OA Initiative Investigator Group. Relationship of compartment-specific
structural knee status at baseline with change in cartilage morphology: a prospective observational study
using data from the osteoarthritis initiative. Arthritis Res Ther. 2009;11(3):R90. Epub 2009 Jun 17.
146.Hunter DJ. One small step in the right direction for MRI measurement performance. Osteoarthritis
Cartilage. 2009 May;17(5):557-8.
147. Hunter DJ, Li L, Zhang YQ, Totterman S, Tamez J, Kwoh CK, Eaton CB, Hellio Le Graverand MP,
Beals CR; for the OAI Investigators. Region of interest analysis: by selecting regions with denuded
areas can we detect greater amounts of change? Osteoarthritis Cartilage. 2009 Aug 29. [Epub ahead of print]
148. Zhang B, Lin H, Hunter DJ., Neogi T, Wise B, Choy E, Niu J, Zhang Y. A Multistate Transition
Model for Osteoarthritis Pain Change. Communications in Statistics - Theory and Methods. 2009; 38:18, 32973306.
149.Stein V, Li L, Guermazi A, Zhang Y, Kent Kwoh C, Eaton CB, Hunter DJ; for the OAI Investigators.
The relation of femoral notch stenosis to ACL tears in persons with knee osteoarthritis. Osteoarthritis
Cartilage. 2009 Oct 2. [Epub ahead of print]
150.Jung KA, Lee SC, Hwang SH, Yang KH, Kim DH, Sohn JH, Song SJ, Hunter DJ. High frequency of
meniscal hypertrophy in persons with advanced varus knee osteoarthritis. Rheumatol Int. 2009 Oct 14.
[Epub ahead of print]
151.Wise BL, Demissie S, Cupples LA, Felson DT, Yang M, Shearman AM, Aliabadi P, Hunter DJ. The
Relationship of Estrogen Receptor-{alpha} and -{beta} Genes with Osteoarthritis of the Hand. J
Rheumatol. 2009 Nov 2. [Epub ahead of print]
152.Bennell KL, Creaby MW, Wrigley TV, Bowles KA, Hinman RS, Cicuttini F, Hunter DJ. Bone marrow
lesions are related to dynamic knee loading in medial knee osteoarthritis. Ann Rheum Dis. 2009 Nov 11.
[Epub ahead of print]
153.Crema MD, Guermazi A, Li L, Nogueira-Barbosa MH, Marra MD, Roemer FW, Eckstein F, Hellio Le
Graverand MP, Wyman BT, Hunter DJ. The association of prevalent medial meniscal pathology with
cartilage loss in the medial tibiofemoral compartment over a 2-year period. Osteoarthritis Cartilage. 2009
Nov 12. [Epub ahead of print]
154.Hunter DJ, Wilson DR. Imaging the role of biomechanics in osteoarthritis. Rheum Dis Clin North Am.
2009 Aug;35(3):465-83.
155.Hunter DJ. Imaging insights on the epidemiology and pathophysiology of osteoarthritis. Rheum Dis Clin
North Am. 2009 Aug;35(3):447-63.
156.Kalichman L, Hodges P, Li L, Guermazi A, Hunter DJ. Changes in paraspinal muscles and their
association with low back pain and spinal degeneration: CT study. Eur Spine J. 2009 Dec 24.
157.Kalichman L, Hunter DJ, Kim DH, Guermazi A. Association between disc degeneration and
degenerative spondylolisthesis? Pilot study. J Back Musculoskelet Rehabil. 2009;22(1):21-5.
158.Kalichman L, Guermazi A, Li L, Hunter DJ. Association between age, sex, BMI and CT-evaluated
spinal degeneration features. J Back Musculoskelet Rehabil. 2009;22(4):189-95.
159.Kalichman L, Kim DH, Li L, Guermazi A, Hunter DJ. Computed tomography-evaluated features of
spinal degeneration: prevalence, intercorrelation, and association with self-reported low back pain. Spine
J.
160.Kalichman L, Guermazi A, Li L, Hunter DJ, Suri P. Facet Orientation and Tropism: Associations With
Spondylolysis. J Spinal Disord Tech. 2010 Jan 12.
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161.Bennell KL, Hunt MA, Wrigley TV, Hunter DJ, McManus FJ, Hodges PW, Li L, Hinman RS. Hip
strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus
malalignment: a randomised controlled trial. Osteoarthritis Cartilage. 2010 Feb 6. [Epub ahead of print]
162.Eckstein F, Wirth W, Hunter DJ, Guermazi A, Kwoh CK, Nelson DR, Benichou O; OAI investigators.
Magnitude and Regional Distribution of Cartilage Loss Associated with Grades of Joint Space
Narrowing in Radiographic Osteoarthritis - Data from the Osteoarthritis Initiative (OAI). Osteoarthritis
Cartilage. 2010 Feb 17. [Epub ahead of print]
163.Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, Bierma-Zeinstra S, Brandt
KD, Croft P, Doherty M, Dougados M, Hochberg M, Hunter DJ, Kwoh K, Lohmander LS, Tugwell P.
OARSI recommendations for the management of hip and knee osteoarthritis Part III: changes in
evidence following systematic cumulative update of research published through January 2009.
Osteoarthritis Cartilage. 2010 Feb 11. [Epub ahead of print]
164.Wirth W, Benichou O, Kwoh CK, Guermazi A, Hunter D, Putz R, Eckstein F; for the OAI
Investigators. Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees:
Data from the osteoarthritis initiative. Magn Reson Med. 2010 Feb 9;63(3):574-581. [Epub ahead of print]
165.Hunter DJ, Bowes MA, Eaton CB, Holmes AP, Mann H, Kwoh CK, Maciewicz RA, Samuels J,
Waterton JC. Can cartilage loss be detected in knee osteoarthritis (OA) patients with 3-6 months'
observation using advanced image analysis of 3T MRI? Osteoarthritis Cartilage. 2010 Feb 26. [Epub ahead of
print]
166.Hunter DJ, Losina E, Guermazi A, Burstein D, Lassere MN, Kraus V. A Pathway and Approach to
Biomarker Validation and Qualification for Osteoarthritis Clinical Trials. Curr Drug Targets. 2010 Mar 4.
[Epub ahead of print]
167.Richmond J, Hunter D, Irrgang J, Jones MH, Snyder-Mackler L, Van Durme D, Rubin C, Matzkin EG,
Marx RG, Levy BA, Watters WC 3rd, Goldberg MJ, Keith M, Haralson RH 3rd, Turkelson CM, Wies
JL, Anderson S, Boyer K, Sluka P, St Andre J, McGowan R. American Academy of Orthopaedic
Surgeons clinical practice guideline on the treatment of osteoarthritis (OA) of the knee. J Bone Joint Surg
Am. 2010 Apr;92(4):990-3. No abstract available.
168.Suri P, Hunter DJ, Jouve C, Hartigan C, Limke J, Pena E, Swaim B, Li L, Rainville J. Inciting events
associated with lumbar disc herniation. Spine J. 2010 Mar 26. [Epub ahead of print]
169.Wise B, Niu J, Zhang Y, Wang N, Jordan J, Choy E, Hunter DJ. Psychological factors and their relation
to osteoarthritis pain. Osteoarthritis Cartilage. 2010 Mar 23. [Epub ahead of print]
170.McWalter EJ, Hunter DJ, Wilson DR. The effect of load magnitude on three-dimensional patellar
kinematics in vivo. J Biomech. 2010 Jul 20;43(10):1890-7.
171.Schneider E, Lo GH, Sloane G, Fanella L, Hunter DJ, Eaton CB, McAlindon TE. Magnetic resonance
imaging evaluation of weight-bearing subchondral trabecular bone in the knee. Skeletal Radiol. 2011
Jan;40(1):95-103.
172.Suri P, Rainville J, Katz JN, Jouve C, Hartigan C, Limke J, Pena E, Li L, Swaim B, Hunter DJ. The
Accuracy of the Physical Examination for the Diagnosis of Midlumbar and Low Lumbar Nerve Root
Impingement. Spine (Phila Pa 1976). 2011 Jan 1;36(1):63-73.
173.Benichou OD, Hunter DJ, Nelson DR, Guermazi A, Eckstein F, Kwoh K, Myers SL, Wirth W, Duryea
J; Osteoarthritis Initiative Investigators. One-year change in radiographic joint space width in patients
with unilateral joint space narrowing: Data from the osteoarthritis initiative. Arthritis Care Res (Hoboken).
2010 Jul;62(7):924-31.
174.Duryea J, Neumann G, Niu J, Totterman S, Tamez J, Dabrowski C, Le Graverand MP, Luchi M, Beals
CR, Hunter DJ. Comparison of radiographic joint space width with magnetic resonance imaging
cartilage morphometry: Analysis of longitudinal data from the osteoarthritis initiative. Arthritis Care Res
(Hoboken). 2010 Jul;62(7):932-7.
175.Hunter DJ, Neogi T, Hochberg MC. Quality of osteoarthritis management and the need for reform in
the US. Arthritis Care Res (Hoboken). 2011 Jan;63(1):31-8.
176.Kim I, Kim HA, Seo YI, Song YW, Hunter DJ, Jeong JY, Kim DH. Tibiofemoral osteoarthritis affects
quality of life and function in elderly Koreans, with women more adversely affected than men. BMC
Musculoskelet Disord. 2010 Jun 22;11:129.
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177.Kim DH, Spencer M, Davidson SM, Li L, Shaw JD, Gulczynski D, Hunter DJ, Martha JF, Miley GB,
Parazin SJ, Dejoie P, Richmond JC. Institutional Prescreening for Detection and Eradication of
Methicillin-Resistant Staphylococcus aureus in Patients Undergoing Elective Orthopaedic Surgery. J
Bone Joint Surg Am. 2010 Aug 4;92(9):1820-6.
178.Suri P, Katz JN, Rainville J, Kalichman L, Guermazi A, Hunter DJ. Vascular disease is associated with
facet joint osteoarthritis. Osteoarthritis Cartilage. 2010 Sep;18(9):1127-32.
179.Harvey WF, Hunter DJ. Pharmacologic Intervention for Osteoarthritis in Older Adults. Clin Geriatr
Med. 2010 Aug;26(3):503-515.
180.Gruber WH, Hunter DJ. Transforming Osteoarthritis Care in an Era of Health Care Reform. Clin
Geriatr Med. 2010 Aug;26(3):433-444.
181.Hunter DJ. Quality of Osteoarthritis Care for Community-Dwelling Older Adults. Clin Geriatr Med.
2010 Aug;26(3):401-417.
182.Hunter DJ. Preface. Clin Geriatr Med. 2010 Aug;26(3):xi-xiii.
183.Johnston JD, McLennan CE, Hunter DJ, Wilson DR. In vivo precision of a depth-specific topographic
mapping technique in the CT analysis of osteoarthritic and normal proximal tibial subchondral bone
density. Skeletal Radiol. 2011 Aug; 40 (8), 1057-64.
184.Suri P, Morgenroth DC, Kwoh CK, Bean JF, Kalichman L, Hunter DJ. Low back pain and other
musculoskeletal pain comorbidities in individuals with symptomatic osteoarthritis of the knee: Data
from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2010 Dec;62(12):1715-23.
185.Larsen KA, Kelly SE, Stern TA, Bode RH Jr, Price LL, Hunter DJ, Gulczynski D, Bierbaum BE,
Sweeney GA, Hoikala KA, Cotter JJ, Potter AW. Administration of olanzapine to prevent
postoperative delirium in elderly joint-replacement patients: a randomized, controlled trial.
Psychosomatics. 2010 Sep;51(5):409-18.
186.Kim DH, Dai F, Belfer I, Banco RJ, Martha JF, Tighiouart H, Tromanhauser SG, Jenis LG, Hunter DJ,
Schwartz CE. Polymorphic Variation of the GTP Cyclohydrolase 1 Gene Predicts Outcome in Patients
Undergoing Surgical Treatment for Lumbar Degenerative Disc Disease. Spine (Phila Pa 1976). 2010
Oct 1;35(21):1909-14.
187.Hunter DJ, Pike MC, Jonas BL, Kissin E, Krop J, McAlindon T. Phase 1 safety and tolerability study of
BMP-7 in symptomatic knee osteoarthritis. BMC Musculoskelet Disord. 2010 Oct 10;11(1):232.
188.Holt HL, Katz JN, Reichmann WM, Gerlovin H, Wright EA, Hunter DJ, Jordan JM, Kessler CL,
Losina E. Forecasting the burden of advanced knee osteoarthritis over a 10-year period in a cohort of
60-64 year-old US adults. Osteoarthritis Cartilage. 2011 Jan;19(1):44-50.
189.Hunter DJ. Pharmacologic therapy for osteoarthritis--the era of disease modification. Nat Rev
Rheumatol. 2011 Jan;7(1):13-22.
190.Hunter DJ, Zaim S, Mosher TJ. What semi-quantitative scoring instrument for knee OA MRI should
you use? Osteoarthritis Cartilage. 2010 Nov;18(11):1363-4.
191.Suri P, Hunter DJ, Katz JN, Li L, Rainville J. Bias in the Physical Examination of Patients with Lumbar
Radiculopathy. BMC Musculoskelet Disord. 2010 Nov 30;11(1):275.
192.Been E, Li L, Hunter DJ, Kalichman L. Geometry of the vertebral bodies and the intervertebral discs in
lumbar segments adjacent to spondylolysis and spondylolisthesis: pilot study. Eur Spine J. 2011
Jul;20(7):1159-65.
193.Buck RJ, Wyman BT, Hellio Le Graverand MP, Hunter D, Vignon E, Wirth W, Eckstein F. Using
Ordered Values of Subregional Cartilage Thickness Change Increases Sensitivity in Detecting Risk
Factors for Osteoarthritis Progression. Osteoarthritis Cartilage. 2011 Mar;19(3):302-8.
194.Gross KD, Felson DT, Niu J, Hunter DJ, Guermazi A, Roemer FW, Dufour AB, Gensure RH,
Hannan MT. Association of flat feet with knee pain and cartilage damage in older adults. Arthritis Care
Res (Hoboken). 2011 Jul;63(7):937-44.
195.Hunter DJ, Harvey W, Gross KD, Felson D, McCree P, Li L, Hirko K, Zhang B, Bennell K. A
Randomized Trial of Patellofemoral Bracing for Treatment of Patellofemoral Osteoarthritis.
Osteoarthritis Cartilage. 2011 Jul;19(7):792-800.
196.Stein V, Li L, Lo G, Guermazi A, Zhang Y, Kent Kwoh C, Eaton CB, Hunter DJ. Pattern of joint
damage in persons with knee osteoarthritis and concomitant ACL tears. Rheumatol Int. 2011 Jan 21.
[Epub ahead of print]
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197.Hunter DJ. Lower extremity osteoarthritis management needs a paradigm shift. Br J Sports Med. 2011
Apr;45(4):283-8.
198.Hayashi D, Guermazi A, Hunter DJ. Osteoarthritis year 2010 in review: imaging. Osteoarthritis
Cartilage. 2011 Apr;19(4):354-60.
199.Losina E, Walensky RP, Reichmann WM, Holt HL, Gerlovin H, Solomon DH, Jordan JM, Hunter DJ,
Suter LG, Weinstein AM, Paltiel AD, Katz JN. Impact of obesity and knee osteoarthritis on morbidity
and mortality in older Americans. Ann Intern Med. 2011 Feb 15;154(4):217-26.
200.Kalichman L, Li L, Hunter DJ, Been E. Association between computed tomography-evaluated lumbar
lordosis and features of spinal degeneration, evaluated in supine position. Spine J. 2011 Apr;11(4):30815.
201.McWalter EJ, Hunter DJ, Harvey WF, McCree P, Hirko KA, Felson DT, Wilson DR. The effect of a
patellar brace on three-dimensional patellar kinematics in patients with lateral patellofemoral
osteoarthritis. Osteoarthritis Cartilage. 2011 Jul;19(7):801-8.
202.Reichmann WM, Maillefert JF, Hunter DJ, Katz JN, Conaghan PG, Losina E. Responsiveness to
change and reliability of measurement of radiographic joint space width in osteoarthritis of the knee: a
systematic review. Osteoarthritis Cartilage. 2011 May;19(5):550-6.
203.Conaghan PG, Hunter DJ, Maillefert JF, Reichmann WM, Losina E. Summary and recommendations
of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group. Osteoarthritis
Cartilage. 2011 May;19(5):606-10.
204.Hunter DJ, Zhang W, Conaghan PG, Hirko K, Menashe L, Reichmann WM, Losina E. Responsiveness
and reliability of MRI in knee osteoarthritis: a meta-analysis of published evidence. Osteoarthritis
Cartilage. 2011 May;19(5):589-605.
205.Hunter DJ, Zhang W, Conaghan PG, Hirko K, Menashe L, Li L, Reichmann WM, Losina E. Systematic
review of the concurrent and predictive validity of MRI biomarkers in OA. Osteoarthritis Cartilage.
2011 May;19(5):557-88.
206.Suri P, Hunter DJ, Jouve C, Hartigan C, Limke J, Pena E, Li L, Luz J, Rainville J. Nonsurgical
treatment of lumbar disk herniation: are outcomes different in older adults? J Am Geriatr Soc. 2011
Mar;59(3):423-9.
207.Brand C, Hunter D, Hinman R, March L, Osborne R, Bennell K. Improving care for people with
osteoarthritis of the hip and knee: How has national policy for osteoarthritis been translated into
service models in Australia? Int J Rheum Dis. 2011 May;14(2):181-190.
208.Guermazi A, Hunter DJ, Li L, Benichou O, Eckstein F, Kwoh CK, Nevitt M, Hayashi D. Different
thresholds for detecting osteophytes and joint space narrowing exist between the site investigators and
the centralized reader in a multicenter knee osteoarthritis study-data from the Osteoarthritis Initiative.
Skeletal Radiol. 2011 Apr 9.
209.Crema MD, Hunter DJ, Roemer FW, Li L, Marra MD, Nogueira-Barbosa MH, Hellio Le Graverand
MP, Wyman BT, Guermazi A. The relationship between prevalent medial meniscal intrasubstance
signal changes and incident medial meniscal tears in women over a 1-year period assessed with 3.0 T
MRI. Skeletal Radiol. 2011 Aug;40(8):1017-23.
210.Roemer FW, Hunter DJ, Winterstein A, Li L, Kim YJ, Cibere J, Mamisch TC, Guermazi A. Hip
osteoarthritis MRI scoring system (HOAMS): reliability and associations with radiographic and clinical
findings. Osteoarthritis Cartilage. 2011 Aug;19(8):946-62.
211.Matthews GL, Hunter DJ. Emerging drugs for osteoarthritis. Expert Opin Emerg Drugs. 2011
Sep;16(3):479-91.
212.Hunter DJ, Guermazi A, Lo GH, Grainger AJ, Conaghan PG, Boudreau RM, Roemer FW. Evolution
of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score).
Osteoarthritis Cartilage. 2011 Aug;19(8):990-1002.
213.Eckstein F, Le Graverand MP, Charles HC, Hunter DJ, Kraus VB, Sunyer T, Nemirovskyi O, Wyman
BT, Buck R; for the A9001140, investigators. Clinical, radiographic, molecular and MRI-based
predictors of cartilage loss in knee osteoarthritis. Ann Rheum Dis. 2011 Jul;70(7):1223-1230.
214.Hunter DJ, Arden N, Conaghan PG, Eckstein F, Gold G, Grainger A, Guermazi A, Harvey W, Jones
G, Hellio Le Graverand MP, Laredo JD, Lo G, Losina E, Mosher TJ, Roemer F, Zhang W; on behalf
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of the OARSI OA Imaging Working Group. Definition of osteoarthritis on MRI: results of a Delphi
exercise. Osteoarthritis Cartilage. 2011 Aug;19(8):963-969.
215.Lang JE, Scott RD, Lonner JH, Bono JV, Hunter DJ, Li L. Magnitude of Limb Lengthening After
Primary Total Knee Arthroplasty. J Arthroplasty. 2011 Aug 4.
216.Hunter DJ, Eckstein F. From joint anatomy to clinical outcomes in osteoarthritis and cartilage repair:
summary of the fifth annual osteoarthritis imaging workshop. Osteoarthritis Cartilage. 2011 Aug 16.
[Epub ahead of print]
217.Suri P, Miyakoshi A, Hunter DJ, Jarvik JG, Rainville J, Guermazi A, Li L, Katz JN. Does Lumbar
Spinal Degeneration Begin with the Anterior Structures? A Study of the Observed Epidemiology in a
Community-Based Population. BMC Musculoskelet Disord. 2011 Sep 13;12(1):202. [Epub ahead of
print]
218.Menashe L, Hirko K, Losina E, Kloppenburg M, Zhang W, Li L, Hunter DJ. The diagnostic
performance of MRI in osteoarthritis: a systematic review and meta-analysis. Osteoarthritis Cartilage.
2011 Oct 19. [Epub ahead of print]
219.Suri P, Rainville J, Fitzmaurice GM, Katz JN, Jamison RN, Martha J, Hartigan C, Limke J, Jouve C,
Hunter DJ. Acute low back pain is marked by variability: An internet-based pilot study. BMC
Musculoskelet Disord. 2011 Oct 5;12:220.
220.Kim HA, Kim I, Song YW, Kim DH, Niu J, Guermazi A, Crema MD, Hunter DJ, Zhang Y. The
association between meniscal and cruciate ligament damage and knee pain in community residents.
Osteoarthritis Cartilage. 2011 Sep 10. [Epub ahead of print]
221.Hwang SH, Jung KA, Lee WJ, Yang KH, Lee DW, Carter A, Park CH, Hunter DJ. Morphological
changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee.
Osteoarthritis Cartilage. 2011 Nov 13.
222.Rainville J, Childs LA, Peña EB, Suri P, Limke JC, Jouve C, Hunter DJ. Quantification of walking
ability in subjects with neurogenic claudication from lumbar spinal stenosis-a comparative study. Spine
J. 2011 Dec 29. [Epub ahead of print]
223.Zifchock RA, Kirane Y, Hillstrom H, Brown PT A, Backus S, Bogner E, Pavlov H, Chen C, Mandl LA,
Hunter D. Are joint structure and function related to medial knee OA pain? A pilot study. Clin Orthop
Relat Res. 2011 Oct;469(10):2866-73.
224.Hameed F, Hunter DJ, Rainville J, Li L, Suri P. Prevalence of anatomic impediments to interlaminar
lumbar epidural steroid injection. Arch Phys Med Rehabil. 2012 Feb;93(2):339-43.
225.Hunter DJ. Osteoarthritis. Best Pract Res Clin Rheumatol. 2011 Dec;25(6):801-14.
226.Sattler M, Dannhauer T, Hudelmaier M, Wirth W, Sänger AM, Kwoh CK, Hunter DJ, Eckstein F. Side
differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees
with the same radiographic disease stage, but unilateral frequent Pain - Data from the osteoarthritis
initiative. Osteoarthritis Cartilage. 2012 Mar 3. [Epub ahead of print]
227.Hunter D, Gross KD, McCree P, Li L, Hirko K, Harvey WF. Realignment treatment for medial
tibiofemoral osteoarthritis: randomised trial. Ann Rheum Dis. 2012 Feb 29. [Epub ahead of print]
228.Hayashi D, Xu L, Roemer FW, Hunter DJ, Li L, Katur AM, Guermazi A. Detection of osteophytes and
subchondral cysts in the knee with use of tomosynthesis. Radiology. 2012 Apr;263(1):206-15.
229.Hwang SH, Jung KA, Lee WJ, Yang KH, Lee DW, Carter A, Park CH, Hunter DJ. Response to Letter
to the Editor: 'Morphological Changes in the Lateral Meniscus in End Stage Lateral Compartment
Osteoarthritis: translating to clinical practice'. Osteoarthritis Cartilage. 2012 Apr 7. [Epub ahead of
print]
230.Suri P, Rainville J, Hunter DJ, Li L, Katz JN. Recurrence of radicular pain or back pain after
nonsurgical treatment of symptomatic lumbar disk herniation. Arch Phys Med Rehabil. 2012
Apr;93(4):690-5.
231.Hwang BY, Kim SJ, Lee SW, Lee HE, Lee CK, Hunter DJ, Jung KA. Risk Factors for Medial Meniscus
Posterior Root Tear. Am J Sports Med. 2012 May 11. [Epub ahead of print]
232.Suri P, Hunter DJ, Rainville J, Guermazi A, Katz JN. Quantitative assessment of abdominal aortic
calcification and associations with lumbar intervertebral disc height loss: the Framingham Study. Spine
J. 2012 May 4.
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233.Zhang Y, Chen C, Choi H, Chaisson C, Hunter D, Niu J, Neogi T. Purine-rich foods intake and
recurrent gout attacks. Ann Rheum Dis. 2012 May 30. [Epub ahead of print]
234.Hunter DJ, Guermazi A. Imaging techniques in osteoarthritis. PM R. 2012 May;4(5 Suppl):S68-74.
235.Suri P, Morgenroth DC, Hunter DJ. Epidemiology of osteoarthritis and associated comorbidities. PM
R. 2012 May;4(5 Suppl):S10-9.
236.Eckstein F, Kwoh CK, Boudreau RM, Wang Z, Hannon MJ, Cotofana S, Hudelmaier MI, Wirth W,
Guermazi A, Nevitt MC, John MR, Hunter DJ; for the OAI investigators. Quantitative MRI measures
of cartilage predict knee replacement: a case-control study from the Osteoarthritis Initiative. Ann
Rheum Dis. 2012 Jun 23.
237.Bennell KL, Hunter DJ, Hinman RS. Management of osteoarthritis of the knee. BMJ. 2012 Jul
30;345:e4934.
238.Bennell K, Hunter DJ, Vicenzino B. Long-term effects of sport: preventing and managing OA in the
athlete. Nat Rev Rheumatol. 2012 Jul 31. [Epub ahead of print]
239.Zhang Y, Neogi T, Chen C, Chaisson C, Hunter D, Choi HK. Cherry consumption and the risk of
recurrent gout attacks. Arthritis Rheum. 2012 Sep 28.
240.Katz JN, Chaisson CE, Cole B, Guermazi A, Hunter DJ, Jones M, Levy BA, Mandl LA, Martin S, Marx
RG, Safran-Norton C, Roemer FW, Skoniecki D, Solomon DH, Spindler KP, Wright J, Wright RW,
Losina E. The MeTeOR Trial (Meniscal Tear in Osteoarthritis Research): Rationale and design features.
Contemp Clin Trials. 2012 Nov;33(6):1189-96.
241.Seah S, Wheaton D, Li L, Dyke JP, Talmo C, Harvey WF, Hunter DJ. The relationship of tibial bone
perfusion to pain in knee osteoarthritis. Osteoarthritis Cartilage. 2012 Sep 7. [Epub ahead of print]
242.Bloecker K, Guermazi A, Wirth W, Benichou O, Kwoh CK, Hunter DJ, Englund M, Resch H,
Eckstein F. Tibial coverage, meniscus position, size and damage in knees discordant for joint space
narrowing - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2012 Dec 5.
243.Johnson VL, Giuffre BM, Hunter DJ. Osteoarthritis: What Does Imaging Tell Us about Its Etiology?
Semin Musculoskelet Radiol. 2012 Nov;16(5):410-8.
244.Losina E, Weinstein AM, Reichmann WM, Burbine SA, Solomon DH, Daigle ME, Rome BN, Chen
SP, Hunter DJ, Suter LG, Jordan JM, Katz JN. Lifetime risk and age of diagnosis of symptomatic knee
osteoarthritis in the US. Arthritis Care Res (Hoboken). 2012 Nov 30.
245.Hochberg M, Chevalier X, Henrotin Y, Hunter DJ, Uebelhart D. Symptom and structure modification
in osteoarthritis with pharmaceutical-grade chondroitin sulfate: what's the evidence? Curr Med Res
Opin. 2012 Nov 27.
246.Ding C, Zhang Y, Hunter D. Use of imaging techniques to predict progression in osteoarthritis. Curr
Opin Rheumatol. 2013 Jan;25(1):127-35.
247.Losina E, Daigle ME, Reichmann WM, Suter LG, Hunter DJ, Solomon DH, Walensky RP, Jordan JM,
Burbine SA, Paltiel AD, Katz JN. Disease-modifying drugs for knee osteoarthritis: can they be costeffective? Osteoarthritis Cartilage. 2013 Feb 1. [Epub ahead of print]
248.Hunter D. Degeneration of the meniscus and progression of osteoarthritis. HSS J. 2012 Feb;8(1):13-4.
249.Zhang Y, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi H. Low-dose aspirin use and recurrent gout
attacks. Ann Rheum Dis. 2013 Jan 23. [Epub ahead of print]
250.Hunter DJ. Osteoarthritis. Rheum Dis Clin North Am. 2013 Feb;39(1):xv-xviii.
251.Eyles J, Lucas BR, Hunter DJ. Targeting care: tailoring nonsurgical management according to clinical
presentation. Rheum Dis Clin North Am. 2013 Feb;39(1):213-33.
252.Riordan EA, Frobell RB, Roemer FW, Hunter DJ. The health and structural consequences of acute
knee injuries involving rupture of the anterior cruciate ligament. Rheum Dis Clin North Am. 2013
Feb;39(1):107-22.
253.Guermazi A, Hayashi D, Eckstein F, Hunter DJ, Duryea J, Roemer FW. Imaging of osteoarthritis.
Rheum Dis Clin North Am. 2013 Feb;39(1):67-105.
254.Bennell KL, Egerton T, Bills C, Gale J, Kolt GS, Bunker SJ, Hunter DJ, Brand CA, Forbes A, Harris A,
Hinman RS. Addition of telephone coaching to a physiotherapist-delivered physical activity program in
people with knee osteoarthritis: A randomised controlled trial protocol. BMC Musculoskelet Disord.
2012 Dec 11;13:246.
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255.Hunter D, Eckstein F, Kraus VB, Losina E, Sandell L, Guermazi A. Imaging Biomarker Validation and
Qualification Report: 6th OARSI Workshop on Imaging in Osteoarthritis Combined with 3rd OA
Biomarkers Workshop. Osteoarthritis Cartilage. 2013 Apr 29. [Epub ahead of print]
256.Kraus VB, Feng S, Wang S, White S, Ainslie M, Le Graverand MP, Brett A, Eckstein F, Hunter DJ,
Lane NE, Taljanovic MS, Schnitzer T, Charles HC. Subchondral bone trabecular integrity predicts and
changes concurrently with radiographic and MRI determined knee osteoarthritis progression. Arthritis
Rheum. 2013 Apr 10. [Epub ahead of print]
257.Atukorala I, Hunter DJ. Valdecoxib : the rise and fall of a COX-2 inhibitor. Expert Opin
Pharmacother. 2013 Mar 22. [Epub ahead of print]
258.van der Esch M, Knoop J, Hunter DJ, Klein JP, van der Leeden M, Knol DL, Reiding D, Voorneman
RE, Gerritsen M, Roorda LD, Lems WF, Dekker J. The association between reduced knee joint
proprioception and medial meniscal abnormalities using MRI in knee osteoarthritis: results from the
Amsterdam osteoarthritis cohort. Osteoarthritis Cartilage. 2013 May;21(5):676-81.
259.Ruhdorfer A, Dannhauer T, Wirth W, Hitzl W, Kwoh CK, Guermazi A, Hunter DJ, Benichou O,
Eckstein F. Thigh muscle cross-sectional areas and strength in advanced versus early painful
osteoarthritis-An exploratory between-knee, within-person comparison in osteoarthritis initiative
participants. Arthritis Care Res (Hoboken). 2013 Feb 11. doi: 10.1002/acr.21965. [Epub ahead of print]
260.Losina E, Daigle ME, Suter LG, Hunter DJ, Solomon DH, Walensky RP, Jordan JM, Burbine SA,
Paltiel AD, Katz JN. Disease-modifying drugs for knee osteoarthritis: can they be cost-effective?
Osteoarthritis Cartilage. 2013 May;21(5):655-67.
261.Zhang Y, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi H. Low-dose aspirin use and recurrent gout
attacks. Ann Rheum Dis. 2013 Jan 23. [Epub ahead of print]
262.Little CB, Hunter DJ. Post-traumatic osteoarthritis: from mouse models to clinical trials. Nat Rev
Rheumatol. 2013 May 21. doi: 10.1038/nrrheum.2013.72. [Epub ahead of print]
263.Della Croce U, Crapanzano F, Li L, Kasi PK, Patritti BL, Mancinelli C, Hunter DJ, Stamenović D,
Harvey WF, Bonato P. A Preliminary Assessment of a Novel Pneumatic Unloading Knee Brace on the
Gait Mechanics of Patients with Knee Osteoarthritis. PM R. 2013 Jun 27. doi:pii: S19341482(13)00349-3.
264.Xu L, Hayashi D, Guermazi A, Hunter DJ, Li L, Winterstein A, Bohndorf K, Roemer FW. The
diagnostic performance of radiography for detection of osteoarthritis-associated features compared
with MRI in hip joints with chronic pain. Skeletal Radiol. 2013 Jul 11. [Epub ahead of print]
265.Messier SP, Mihalko SL, Beavers DP, Nicklas BJ, Devita P, Carr JJ, Hunter DJ, Williamson JD, Bennell
KL, Guermazi A, Lyles M, Loeser RF. Strength Training for Arthritis Trial (START): design and
rationale. BMC Musculoskelet Disord. 2013 Jul 15;14(1):208. [Epub ahead of print]
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Books
Living with Arthritis.
Author: David Hunter
ISBN : 0733315321
APN : 9780733315329
Publisher : ABC Books & Audio / BBC Audio
Format : Paperback
Number of pages : 224
Publication Date : January, 2006
Osteoarthritis
Authors: Nigel K Arden, Elizabeth Arden and David Hunter
ISBN-10: 0199211388
ISBN-13: 978-0199211388
APN : 9780733315329
Publisher : Oxford University Press, USA; 6th Ed edition (May 28, 2008)
Format : Paperback
Number of pages :184
Publication Date : May, 2008
Osteoarthritis Online Primer
Editors: David Hunter, Yves Henrotin, Hiroshi Kawaguchi
Online link:
http://www.oarsi.org/index2.cfm?section=Publications_and_Newsroom&content=Press_
Releases/2011/primer_online
Book Chapters
Pharmacology and Therapeutics - Principles to Practice. Edited by By Scott A. Waldman, MD, PhD, FCP
and Andre Terzic, MD, PhD. Chapter on Osteoarthritis. ISBN: 978-1-4160-6098-7.
The role of subchondral bone pathology in osteoarthritis. The new science of osteoarthritis - from bench to
bedside. Ed J Dickson, R Hughes, D Marsh. Royal Society of Medicine Publications 2008
Assessment of Imaging Outcomes in OA. Rheumatology. Editors: Hochberg, Silman, Smolen, Weinblatt,
Weisman. Edition5. Publisher: Elsevier Health Sciences, 2010. ISBN0323086322, 9780323086325
Clinical aspects: A Rheumatologist’s Perspective. Cartilage Imaging. Editor: Thomas Link. Publisher:
Spriner Verlag. ISBN: 9781441984371. June 2011
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Invited Presentations at National/International Meetings
 Guest Speaker Australian Sports Medicine Federation National Conference 1998.

“Corticosteroids, Osteoporosis and the Australian Rheumatologist”, poster at National ARA Meeting
1998, abstract in ANZJM.

“Effects of Corticosteroid Use and Disease Activity on Bone Assessed by Quantitative Ultrasound in
Patients with Rheumatoid Arthritis”, D Hunter, P Sambrook et al. Poster ACR National Scientific Meeting,
November 1998.

"Genetic Influence on Bone resorption, Sodium and Calcium Excretion: A Study of 2170 Twins".
Hunter DJ, MacGregor A, Keen RW, Snieder H, Swaminathan R, Thakker R, Spector TD. Poster at
ASBMR Annual Meeting. J Bone Min Research. 1999; 14(Suppl 1): S191.

"Genetic Influence on Bone resorption, Sodium and Calcium Excretion: A Study of 2170 Twins".
Hunter DJ, MacGregor A, Keen RW, Snieder H, Swaminathan R, Thakker R, Spector TD. Oral
presentation at American College of Rheumatology meeting Nov, 1999. Arthritis and Rheumatism. 1999; 42
No.9(Suppl): S633.

"Inflammation and bone turnover in cervical and lumbar disc degenerative disease". Hunter DJ,
Sambrook PN, Pepys MB, Spector TD. Poster at National ARA Meeting April 2000.

"The influence of menopause on the genetic variation in bone mineral density and calcaneal ultrasound:
A Study of Female Twins". Hunter DJ, de Lange M, Snieder H, MacGregor AJ, Spector TD. Poster at
National ARA Meeting April 2000. ANZ Journal of Medicine. 2000; Vol 30(4): 537.

"The influence of menopause on the genetic variation in bone mineral density and calcaneal ultrasound:
A Study of Female Twins". Hunter DJ, de Lange M, Snieder H, MacGregor AJ, Spector TD. Oral
Presentation at British Society of Rheumatology Meeting, May 2000. Rheumatology. 2000; Vol 39 (Suppl 1):
329.

Guest speaker at NSW Australian Orthopaedic Association Annual Scientific Meeting- "Structure
Modifying Agents for Osteoarthritis", July 2000.

Guest Speaker at Westmead Rheumatology Seminar on Genetics of Osteoarthritis, July 2000.

"The Association of Altered Bone Turnover and Calcium Regulation with Knee Osteoarthritis in
Female Twins," DJ Hunter, D Hart, T Andrew, H Snieder, AJ MacGregor, P Bettica, TD Spector. Oral
presentation, Osteoarthritis Research Society International, October 2000. Osteoarthritis and Cartilage.
2000; Vol 8(Suppl B): S9.

Altered Cartilage Metabolism Linked to Knee Osteoarthritis: A Mother-Daughter Study. D Hunter, V
Naganathan, L March, J Zochling, D Clemens, L Atley, T Pietka, D Eyre, P Sambrook. Oral Presentation,
ACR, Philadelphia, Nov 2000. Arthritis and Rheumatism. 2000; 43(9) Suppl: S273.
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
The association of altered subchondral architecture with pain in knee osteoarthritis. David J Hunter,
Lyn March, Philip N Sambrook. ACR, San Francisco, Nov 2001.

Hunter D, Tay H, Peppa D, Warfield S. Reliability of 3D Cartilage Volume Measurements. Arthritis &
Rheumatism 46[9], S151. 2002. American College of Rheumatology Annual Scientific Meeting, Oct 2002.

Hunter DJ, Marsh A, Loch-Wilkinson AM, Pinczewski L, Russell V, Burstein D. MRI Features of
Osteoarthritis following Meniscectomy. Arthritis & Rheumatism 46[9], S152. 2002. American College of
Rheumatology Annual Scientific Meeting, Oct 2002.

A new way to think about hand osteoarthritis: Joint Specific Phenotypes. The Framingham Study. D.J.
Hunter, S. Demissie, L.A. Cupples, P Aliabadi, D.T. Felson. 2003 ACR annual scientific meeting, Orlando.
(plenary).

Increase in Bone marrow lesions is associated with more rapid cartilage loss: A longitudinal MRI study.
DJ Hunter, Y Zhang, J Niu, S Amin, J Goggins, M LaValley, ME Gale, D Gale, DT Felson. 2003 ACR
annual scientific meeting, Orlando. (plenary).

Structural Determinants of Cartilage Loss: The Boston Osteoarthritis Study. Orthopedic Research
Society. 2004.

Change in Joint Space Width: Hyaline cartilage loss or Meniscal Change. 2004 ACR annual scientific
meeting. (plenary).

The etiology of knee pain in the community. The Framingham Study. 2004 ACR annual scientific
meeting.

Cartilage volume must be normalized to bone surface area in order to provide satisfactory construct
validity: The Framingham Study. OARSI. 2004.

NYU Seminar in Advanced Rheumatology. March 2005. Lecture on “Radiograph and MRI in the
Assessment of Osteoarthritis”.

th
6 International Symposium on Bone Architecture and the Competence of Bone & Joints. Salzburg,
Austria. Invited lecture on Measurement of Bone in Osteoarthritis, 2005.

Patellofemoral alignment and PF OA progression. The Framingham Study. 2005 ACR annual scientific
meeting.

NYU Seminar in Advanced Rheumatology. March 2006. Lecture on “Guidelines for Osteoarthritis
Management”.

BU Grand Rounds. “Update on Osteoarthritis”. February 2006.

Controversies in Internal Medicine, Guest Speaker, Hilton Head, May 2006.

Invited lecture; “Update on the Epidemiology of Osteoarthritis”, Paracelsus Medical University,
Salzburg, August 2006.

Muscle and PF OA Progression. 2006 ACR annual scientific meeting.
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
Cartilage markers and their association with cartilage loss on MRI: The Boston Osteoarthritis Knee
Study. OARSI. 2006.

The Role of Bone in Osteoarthritis. Segal Symposium, Chicago. September 2007

The Role of Subchondral Bone in Osteoarthritis. Royal Society of Medicine. London, UK. September
2007.

The Role of Imaging in Osteoarthritis. Invited Lecture, UCSF Radiology Course-Advanced Imaging,
November 2007.

The Role of Subchondral Bone in Osteoarthritis. Orthopedic Grand Rounds, NEBH, December 2007.

New Insights into an ancient disease. Grand Rounds, NYU December 2007.

The Role of Subchondral Bone in Osteoarthritis. Grand Rounds Brown University, February 2008.

The Role of Subchondral Bone in Osteoarthritis. Grand Rounds Brigham and Womens, February 2008.

Advanced Imaging in Arthritis, Invited Lecture, Seminar in Advanced Rheumatology, NYU, March
2008.

When does alignment matter?, Advanced Imaging and Computer Assisted Surgery, AAOS/ORS
Meeting, Providence RI May 2008.

Osteoarthritis: Engaging the Clinician. Advances in Rheumatology, Harvard Medical School, Boston,
September 2008.

Risk stratification for OA Progression, Invited Lecture, OARSI, Rome, Italy September 2008.

What have we learned about OA progression from MRI, Invited Lecture, APLAR, Yokohama, Japan,
September 2008.

Invited participant and speaker, OA Risk Factors Workshop, NIAMS, October 2008.

Osteoarthritis Update 2008. Meet the professor, ACR, San Francisco, October 2008.

Oral presentation entitled: Cartilage morphometry region of interest analysis; by selecting regions with
denuded areas can we detect greater amounts of change? ACR, San Francisco, October 2008.

Co –Chair and Scientific Committee, 3rd Annual OA Imaging Workshop, Leeds UK, May 2009.

Invited Speaker, Puerto Rican International Rheumatology Meeting, June 2009.

Invited Speaker, Segal North American Osteoarthritis Workshop (SNOW) Meeting, Chicago, October
2009.

Invited Speaker, BJD Global Conference, Washington DC, October 2009.

Invited Speaker, Orthopedic Grand Rounds Brigham and Womens Hospital, Disease modification in
osteoarthritis-challenges and new developments, October 2009

Invited Speaker, Boston Sports and Shoulder Symposium, Osteoarthritis management in clinical
practice; How are we doing? November 2009

Osteoarthritis consultant, RSNA Imaging Biomarkers Roundtable, Chicago, November 2009.
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CURRICULUM VITAE

Meeting organizer and plenary presenter, OA Imaging Workshop, Vancouver Canada, June 2010

Invited Speaker, Prevention and Management of Osteoarthritis in the Athlete, July 2010. AIS Canberra.

Invited Speaker, RSNA Biomarkers Roundtable, Chicago, September 2010.

Invited Speakers, OARSI Annual Scientific Meeting, Imaging Year in Review, Brussels, September
2010.

Plenary Presentation, OARSI Annual Scientific Meeting, Reliability and Responsiveness of MRI Meta-
Analysis”, Brussels, September 2010.

Invited Speaker, Clinical Research in OA, OARSI-China Forum, Nanjing China, October 2010.

Invited Speaker, Prevention of Arthritis Following Sport, London UK, October 2010.

Invited Speaker, GPCE Sydney. The Epidemic of Osteoarthritis is here: what should you do? April
2011.

Invited Speaker, Beijing Health Research Lecture Series, OA Management needs a Paradigm Shift,
Beijing, May 2011.

Invited Speaker, Role of Mechanics in Etiology of Knee OA, Peking University 2011 OA International
Forum, Beijing, May 2011.

Invited Speaker, Etiology and Management of Hand OA, Hand Arthritis Workshop, Macquarie
Hospital. May 2011.

Invited Speaker, Review of the relationship between MR imaging biomarkers and clinical outcomes in
OA, 5th Annual OA Imaging Workshop, Salzburg, Austria, June 2011.

Invited Speaker, Role of the Meniscus, HSS Osteoarthritis Summit, New York, June 2011.

Convener Bone and Joint Decade Forum, Parliament House, June 23rd, 2011.

Royal North Shore Physiotherapy, Management of Osteoarthritis, June 30th 2011.

Keynote Speaker, Japanese College of Rheumatology Meeting. ( Kobe Japan) Progression in
Osteoarthritis, July 2011.

Update on osteoarthritis, Australian Doctor Seminar, August 2011.

Management of OA, ADMA Meeting August 25th 2011, Canberra.

OA Management needs a Paradigm Shift, The First Asia Conference on Osteoarthritis, 9th October
2011, Singapore.

Osteoarthritis Care: Genesis informing management, NSW ARA Meeting, 20th November 2011.

Implementing the osteoarthritis chronic care program, NSW Health Chronic Care Forum, 25th
November 2011.

Monitoring progression or remission - implementation of biomarkers, Keynote Speaker, World
Congress on Debates & Consensus in Bone, Muscle and Joint Diseases (BMJD), Barcelona, Spain January
2012.
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
Osteoarthritis Coordinated Care; Arthritis WA. Perth, March 2012.

Chairperson, OARSI Scientific Meeting, Barcelona, Spain April 2012.

Keynote Speaker, Launch OACCP Model of Care, ACI MSK Forum, May 2012.

Keynote Speaker, Opening of Center for MSK Outcomes Research, Otago University May 2012

Keynote Speaker, Hot Questions in Osteoarthritis, ARA Annual Scientific Meeting May 2012.

Oral presentation, Quantitative Magnetic-Resonance-Imaging Measures of Cartilage Predict Knee
Replacement - A Case-Control Study from the Osteoarthritis Initiative. ARA Annual Scientific Meeting
May 2012.

Managing Osteoarthritis as a Chronic Disease, Concord Hospital Physicians Workshop, June 7th 2012.

Meeting Chair; Osteoarthritis Imaging Workshop, Hilton Head, July 2012.

Keynote Speaker, Pharmacologic Management of Osteoarthritis, Australasian College of Podiatric
Surgeons, Foot and Ankle Insight 2012, Sydney, August 2012.

Invited Speaker, Role of Subchondral Bone in Osteoarthritis, ANZ Bone Mineral Society Meeting,
Perth, September 2012.

Convener, Australian Osteoarthritis Summit, Sydney, November 2012.

Convener, Bone and Joint Decade Symposium, National Sports Injury Conference, Sydney, November
2012.

Invited Speaker, Osteoarthritis Therapeutics: Will this be the decade for breakthroughs? American
College Rheumatology Annual Scientific Meeting, Washington DC, November 2012.

Oral Presentation, IDEA Structural Outcomes, American College Rheumatology Annual Scientific
Meeting, Washington DC, November 2012.

Visiting Professor, Paracelsus Medical University, Salzburg, Austria. January 2013.

Plenary presentation, OARSI Annual Scientific Meeting, Shape and Bone Area Predisposing to OA?,
Philadelphia, April 2013.

Invited keynote speaker, Current medical treatments and disease modification in OA and the role of
imaging in monitoring outcome, Sydney, AMSIG May 2013.
Invited keynote speaker, Coordinated multidisciplinary management: The OA Team, Iceland, Knee
Osteoarthritis Congress May 2013.

Invited keynote speaker, Osteoarthritis management: The OA Team, WEHI June 2013.

Invited keynote speaker, Osteoarthritis Imaging Workshop, Tunisia July 2013.
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CURRICULUM VITAE
Awards
“Assessment of Rheumatological Education of Final Year Medical Undergraduate Students”, D Hunter, L
Schrieber, G Hendry, R Laurent, L March, P Sambrook. Awarded best clinical presentation-NSW ARA
Meeting Nov, 1998.
"The Association of Altered Bone Turnover and Calcium Regulation with Knee Osteoarthritis in Female
Twins," DJ Hunter, D Hart, T Andrew, H Snieder, AJ MacGregor, P Bettica, TD Spector.Young
Investigator Award, Osteoarthritis Research Society International, October 2000.
University of Sydney, Postgraduate Student Conference Travel Grant, 2000.
Beryl & Jack Jacobs Postgraduate Research Award for 2001.
The Spine Journal Editor's Choice Award 2009. “Spinal stenosis prevalence and association with symptoms:
The Framingham Study”.
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CURRICULUM VITAE
Research Support
Active
FT0991246 Hunter (PI)
Australian Research Council
Future Fellowship-The early osteoarthritis (OA) phenotype.
Role: Principal Investigator
Dates of Approved/Proposed Project:
02/01/10 – 01/31/14
Percent Effort:
75%
Annual Direct Costs:
$160,000
BAA NHLBI-AR-10-06 Hunter (Co-PI)
NHLBI
To identify structural changes detectable by MRI that
precede the onset of radiographic knee osteoarthritis
(ROA) and/or that predict the development of important
clinical outcomes.
Role: Co- Principal Investigator
Dates of Approved/Proposed Project:
07/01/10 – 05/4/15
R01 AR059105 Messier (PI)
NIH/NIAMS
Strength Training and Arthritis Trial (START)
To compare two exercise regimes in persons with knee OA
looking at both disease pathway and clinical measurements
of disease severity.
Role: Co-Investigator
Dates of Approved/Proposed Project:
07/01/11 – 06/30/15
Hunter (PI)
Foundation for the National Institutes of Health
Osteoarthritis Biomarker Consortium
Role: Co-Principal Investigator
Dates of Approved/Proposed Project:
07/01/12 – 06/30/14
ARC Discovery: Crossley K, Pandy M, Hunter D, Seeman
E, Schache A
Australian Research Council
Integration of high-speed dynamic x-ray imaging and
patient-specific computational modelling for noninvasive
assessment of knee-joint function
Role: CIC
Dates of Approved/Proposed Project:
01/01/12 – 31/12/14
APP1021639 Hunter (CIA)
NHMRC
Web based study of risk factors for pain exacerbation in knee
osteoarthritis
Role: Principal-Investigator
Dates of Approved/Proposed Project:
01/01/12 – 31/12/14
APP1045890 Hunter (CIB)
NHMRC
Synovial macrophages and T-cells are therapeutic targets in
osteoarthritis
Role: CIB
Dates of Approved/Proposed Project:
01/01/13 – 31/12/15
Percent Effort:
10%
Annual Direct Costs:
$1,100,000
Percent Effort:
5%
Annual Direct Costs:
$20,360
Percent Effort:
5%
Annual Direct Costs:
$50,360
Percent Effort:
5%
Annual Direct Costs:
$180,360
Percent Effort:
10%
Annual Direct Costs:
$120,360
Percent Effort:
5%
$632,127.60 over 3 years
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CURRICULUM VITAE
APP1045890 Hunter (CIC)
NHMRC
Unloading shoes for knee osteoarthritis: a double-blind randomised
controlled trial
Role: CIC
Dates of Approved/Proposed Project:
01/01/13 – 31/12/15
DP130104407 Hunter (CIA)
ARC Discovery Project
Program evaluation of Osteoarthritis Awareness hub
Role: CIA
Dates of Approved/Proposed Project:
01/01/13 – 31/12/15
Percent Effort:
5%
$741,631.31 over 3 years
Percent Effort:
10%
$440,000 over 3 years
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CURRICULUM VITAE
Completed
Defence Health Foundation. Hunter (PI)
Structural factors determining long term outcomes of acute
knee injuries
Role: Principal-Investigator
Dates of Approved/Proposed Project:
01/01/12 – 01/12/12
Title of Project (or Subproject):
The Role of Bone in Osteoarthritis Progression under NIH
Grant No 1R01 AR054938-01, CFDA no 93.846
(McAlindon)
Dates of Approved/Proposed Project:
06/11/07 – 05/31/11
Percent Effort:
5%
Annual Direct Costs:
$47,000
Percent Effort:
3.75%
Annual Direct Costs:
$8,782
Funding Source: NEMC (NIH)
To study the longitudinal role of peri-articular bone in OA
to increase understanding of the mechanisms of
progression, refine predictive models, and suggest tissuetargeted interventions
Title of Project (or Subproject):
Intensive Dietary Restriction with Exercise in Arthritis
(IDEA) under NIH Grant No 5R01 AR052528, CFDA no
93.846 (Messier)
Dates of Approved/Proposed Project:
07/01/07 – 06/30/11
Percent Effort:
2%
Annual Direct Costs:
$6,813
Funding Source: Wake Forest University (NIH)
To asess the effects of intensive dietary restriction-plusexercise on inflammatory biomarkers and knee joint loads.
R01 AR053112-03 Losina (PI)
NIH/NIAMS
Knee OA: Setting Priorities for Care, Policy, Research
Role: Co-Investigator.
Dates of Approved/Proposed Project:
09/01/09 - 08/31/10
Title of Project (or Subproject):
Multidisciplinary Clinical Research Center at
Boston University – (Felson)
Dates of Approved/Proposed Project:
03/01/06 – 02/28/11
Funding Source: NIAMS
Percent Effort:
7%
Annual Direct Costs:
$28,212
Percent Effort:
20%
Annual Direct Costs:
$660,893
This is a multi-project center grant supporting four clinical
research projects including one clinical trial.
Project 2 - PI
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CURRICULUM VITAE
Title of Project (or Subproject):
Knee Osteoarthritis Brace
Dates of Approved/Proposed Project:
06/01/07-11/31/09
Funding Source: The Wallace H. Coulter Translational
Partners Grant Program
Annual Direct Costs:
$120,000
Percent Effort:
20%
This is a 2 year project aimed at designing a new brace for
tibiofemoral OA and assessing its mechanical properties.
Title of Project (or Subproject):
A Methodology Study to Assess Whether Magnetic
Resonance Imaging Using Advanced Image Analysis can be
Used to Measure Changes in Cartilage Thickness in Patients
with Knee Osteoarthritis at Three and Six Months
Dates of Approved/Proposed Project:
8/16/07 – 12/31/09
Percent Effort:
2%
Annual Direct Costs:
$281,835
Funding Source: AstraZeneca Research and Development
The major goal of this project is to investigate the potential
of medial tibio-femoral cartilage quantity, measured by MRI
with advanced image analysis, as a biomarker endpoint for
future 3 month disease modification “Proof of Concept”
(PoC) studies in patients with tibio-femoral (TF)
osteoarthritis (OA) of the knee and mild varus
mal-alignment.
Title of Project (or Subproject):
A Randomized Trial of Realignment Therapy for
Treatment of Medial Knee Osteoarthritis
Funding Source: NIDRR - FIP
Dates of Approved/Proposed Project:
11/1/04 – 10/31/08
Percent Effort:
20%
Annual Direct Costs:
$115,385
The major goal of this project is to determine whether the
provision of realignment therapy in patients with medial
knee OA relieves knee pain and improves function.
Title of Project (or Subproject): A Phase I, Double Blind,
Randomized, Single Dose Escalation Safety Study Of IntraArticular Osteogenic Protein-1 (Op-1) In Subjects With
Osteoarthritis
Funding Source: STRYKER BIOTECH
The major goal of this project are to investigate the safety
and tolerability of OP-1 when it is injected into the knee
joint.
Dates of Approved/Proposed Project:
Percent Effort:
03/22/2007 – 03/21/2008
2%
Annual Direct Costs:
$223,205
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CURRICULUM VITAE
Title of Project (or Subproject):
(BOAMRI) Biomarkers in Osteoarthritis MRI Studies
(Felson)
Funding Source: NIH/NIAMS
The major goal of this project is to identify and characterize
biochemical markers that assess disease risk and
progression.
Title of Project (or Subproject):
International Workshops on Osteoarthritis Imaging
Funding Source: NIH/NIAMS
1 R13 AR056570-01 (Hunter)
The goal of the workshops is to promote applied research
and development to applications of in vivo imaging of
osteoarthritis, with a particular focus on the relations of
imaging biomarkers and clinical outcomes.
Title of Project (or Subproject):
Patellofemoral Osteoarthritis Epidemiology
Funding Source: NIH/NIAMS
1 R03 AR51102-02 (Hunter)
The goal of this study is to use longitudinal data (including
serial MRI) to explore patellofemoral (PF) cartilage loss,
and risk factors for PF OA.
Dr IR Vanderfield Travelling Scholarship-1999.
Dates of Approved/Proposed Project:
09/30/03 – 08/31/08
Percent Effort:
10%
Annual Direct Costs:
$226,088
Dates of Approved/Proposed Project:
06/01/08 – 06/30/08
Percent Effort:
2%
Annual Direct Costs:
$30,000
Dates of Approved/Proposed Project:
07/01/04 – 06/30/07
Percent Effort:
40%
Annual Direct Costs:
$50,000
Arthritis Foundation-Philip Benjamin Grant- 1999.
Lincoln Bone and Joint Research Doctoral Scholarship-2000.
Ramsay Health Care Medical Fellowship-2001.
Cottrell Fellowship-2002.
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