• Water and Minerals Chapter 6 • Water • Functions of water – Occupies essentially every space within and between body cells – Involved in virtually every body function – Largest single constituent of the human body, averaging 60% of total body weight – Provides shape and structure to cells – Regulates body temperature – Aids in the digestion and absorption of nutrients • Water (cont’d) • Functions of water (cont’d) – Transports nutrients and oxygen to cells – Serves as a solvent for vitamins, minerals, glucose, and amino acids – Participates in metabolic reactions – Eliminates waste products – Is a major component of mucus and other lubricating fluids • Water (cont’d) • Water balance – Total body water balance is tightly regulated within +/- 0.2% of body weight – Sensation of thirst and the action of the hormone vasopressin control our daily fluid balance o Water output Adults lose approximately 1,750 to 3,000 mL of water daily Insensible water losses – Water (cont’d) • Water balance (cont’d) • Water output (cont’d) – • Sensible water losses Water intake – Drinking water – Other beverages – Solid foods • Water (cont’d) • Water recommendations • – Body cannot produce as much water as it needs – For men ages 19 to over 70, the adequate intake (AI) is 3.7 L/day – For women of the same age, the AI is 2.7 L/day – Daily intakes below the AI may not be harmful to healthy people – Water (cont’d) Water recommendations (cont’d) – Osmoregulatory system – Fluid intake is assumed to be adequate when the color of urine produced is pale yellow – Elderly and children o – • Drinking fluids should not be delayed until the sensation of thirst occurs Water (cont’d) Water recommendations (cont’d) – Increases in water loss o Vomiting, diarrhea, and fever o Thermal injuries, fistulas, uncontrolled diabetes, hemorrhage, and certain renal disorders o Use of drainage tubes contributes to increased water losses o Intake and output records are used to assess adequacy of intake • Water (cont’d) • Alterations in intake – • • Dehydration is characterized by: o Impaired mental function o Impaired motor control o Increased body temperature during exercise o Increased resting heart rate when standing or lying down o Increased risk of life-threatening heat stroke o Water (cont’d) Alterations in intake (cont’d) – A net water loss of as little as 1% of body weight increases plasma osmolality – A loss of 20% can be life-threatening Hyponatremia – At risk patients include infants; psychiatric patients with excessive thirst; women who have undergone surgery using a uterine distention medium; and athletes in endurance events who drink too much water or fail to replace lost sodium, or both • Water (cont’d) • Hyponatremia (cont’d) – Symptoms o Lung congestion, muscle weakness, lethargy, and confusion o Can progress to convulsions, prolonged coma, and death • Question • Insensible water losses are those that cannot be measured. Insensible water losses occur through what? a. Urine b. Feces c. Respirations d. Diaphoresis • Answer c. Respirations Rationale: Extreme environmental temperatures (very hot or very cold), high altitude, low humidity, and strenuous exercise increase insensible water losses from respirations and the skin. • Keys to Understanding Minerals • Major minerals are present in the body in amounts greater than 5 g • Calcium, phosphorus, magnesium, sulfur, sodium, potassium, and chloride are major minerals • Iron, iodine, zinc, selenium, copper, manganese, fluoride, chromium, and molybdenum are classified as trace minerals or trace elements • Both groups are essential for life • Keys to Understanding Minerals (cont’d) • General chemistry – Minerals are inorganic elements that originate from the earth’s crust, not from plants or animals – Minerals do not undergo digestion, nor are they broken down or rearranged during metabolism – Minerals are not destroyed by light, air, heat, or acids during food preparation • Keys to Understanding Minerals (cont’d) • General functions – • Minerals function to provide structure to body tissues and to regulate body processes Mineral balance – Maintained by: o Releasing minerals from storage for redistribution o Altering rate of absorption o Altering rate of excretion • Keys to Understanding Minerals (cont’d) • Mineral toxicities • – Stored minerals can produce toxicity symptoms – Toxicity related to excessive use of mineral supplements, environmental or industrial exposure, human errors in commercial food processing, or alterations in metabolism Mineral interactions – Mineral status must be viewed as a function of the total diet • Keys to Understanding Minerals (cont’d) • Sources of minerals – • Major electrolytes – – • Unrefined or unprocessed foods have more minerals than refined foods Sodium o Salt (sodium chloride) is approximately 40% sodium o Wide variations in sodium intake exist between cultures and between individuals within a culture Keys to Understanding Minerals (cont’d) Major electrolytes (cont’d) – Sodium (cont.) o Major extracellular cation o Largely responsible for regulating fluid balance o Almost 98% of all sodium consumed is absorbed o Adequate intake for sodium is set at 1,500 mg/ day o 100% of adult men and women exceed the AI of 1,500 mg of sodium/day – Keys to Understanding Minerals (cont’d) – Potassium o Major cation of the intracellular fluid o – When potassium excretion is impaired, such as secondary to diabetes, chronic renal insufficiency, end- stage renal disease, severe heart failure, and adrenal insufficiency, high potassium intakes can lead to hyperkalemia and lifethreatening cardiac arrhythmias Chloride o Major anion in the extracellular fluid o AI for younger adults is 2.3 g/day • Question • Is the following statement true or false? Potassium is the major extracellular cation. • Answer False. Rationale: Most of the body’s potassium is located in the cells as the major cation of the intracellular fluid. • Major Minerals • Calcium – Most plentiful mineral in the body – Probably protects against colorectal cancer – Calcium balance in the blood is achieved through the action of vitamin D and hormones – 3 daily servings of milk, yogurt, or cheese plus nondairy sources of calcium are needed to ensure an adequate calcium intake – An adequate calcium intake throughout the first 3 decades of life is needed to attain peak bone mass as determined by genetics • Major Minerals (cont’d) • Phosphorus – After calcium, the most abundant mineral in the body is phosphorus – About 60% of natural phosphorus from food sources is absorbed – Dietary deficiencies of phosphorus do not occur • Magnesium – 4th most abundant mineral in the body – Mean magnesium intake among American adults is approximately 80% of the RDA • Major Minerals (cont’d) • Sulfur – Does not function independently as a nutrient but is a component of biotin, thiamin, and the amino acids methionine and cysteine – There is no RDA or AI for sulfur • Trace Minerals • Impact on health is significant • Too little of a trace mineral can be just as deadly as too much • Iron – Approximately two-thirds of the body’s 3 to 5 g of iron is contained in the heme portion of hemoglobin – Iron in foods exists in two forms: heme iron found in meat, fish, and poultry, and nonheme iron found in plants such as grains, vegetables, legumes, and nuts – Overall rate of iron absorption is only 10% to 15% of total intake • Trace Minerals (cont’d) • Iron (cont’d) • – Only 1% to 7% of nonheme iron is absorbed from plant foods when they are consumed as a single food – RDA for iron is set at 8 mg for men and postmenopausal women, and at 18 mg for premenopausal women – Iron deficiency anemia o Microcytic, hypochromic anemia o Pica Trace Minerals (cont’d) • • Iron (cont’d) – Potential for toxicity is moderate to high – Hemochromatosis – Acute iron toxicity Zinc – A regular and sufficient intake is necessary – Plays important roles in immune system functioning and in wound healing • Trace Minerals (cont’d) • Iodine • – Essential component of thyroxine (T4) and triiodothyronine (T3) – Approximately 50% of the population uses iodized salt – Goitrogens Selenium – A component of a group of enzymes that function as antioxidants – Selenium deficiency is rare in the United States • Trace Minerals (cont’d) • Copper • – Distributed in muscles, liver, brain, bones, kidneys, and blood – Involved in hemoglobin synthesis, collagen formation, wound healing, and maintenance of nerve fibers Manganese – Dietary deficiencies have not been noted – High manganese intake from drinking water also produces neuromotor deficits similar to Parkinson’s disease • Trace Minerals (cont’d) • Fluoride • – Promotes the mineralization of developing tooth enamel prior to tooth eruption and the remineralization of surface enamel in erupted teeth – Fluoridation of municipal water Chromium – Enhances the action of the hormone insulin to help regulate blood glucose levels – Appears that average intake is adequate • Trace Minerals (cont’d) • Molybdenum • – Plays a role in red blood cell synthesis – Dietary deficiencies and toxicities are unknown Other trace elements – Evidence is difficult to obtain and quantifying human need is even more formidable • Question • Which major mineral is the most abundant in the human body? a. Manganese b. Selenium c. Calcium d. Sodium • Answer c. Calcium Rationale: Calcium is the most plentiful mineral in the body, making up about half of the body’s total mineral content. • Water and Minerals in Health Promotion • Water – Recommended that thirst be the guide to consuming adequate fluid; specific amounts or types of beverages to satisfy fluid need are not suggested – • For healthy people, hydration is unconsciously maintained with ad libitum access to water Sodium and potassium – Recommendations: o Less sodium o More potassium