ZIKA VIRUS INFECTION AND RISKS TO AUSTRALIANS KEY ISSUES Zika virus, transmitted by mosquitos in other countries, is of particular concern for pregnant women as there is a possibility that as it may cause microcephaly (small/underdeveloped brain) in unborn babies. This virus has been known since 1947 and occurs mostly in Africa and Asia. It has come to attention because of an increase in infections associated with an increase in microcephaly in Brazil. There is no vaccine or treatment for this virus. Prevention by avoiding mosquito bites is the best course of action. In recent years outbreaks of Zika virus infection have been reported in the Pacific and South and Central America. Some outbreaks have raised concerns that Zika virus infection might cause certain birth defects if the baby is infected in utero. There has also been an increase in the number of people developing a rare condition that causes paralysis called Guillain-Barré Syndrome. There is a continuing risk of Zika virus being imported into Australia from affected areas, with the risk of local transmission in areas of Central and North Queensland where the mosquito vector is present. TALKING POINTS: Given the seriousness of the possible risk to unborn babies, the Department of Health has provided information to inform travel advice provided by the Department of Foreign Affairs and Trade, which recommends that pregnant women consider deferring travel to affected areas. This advice is consistent with that of other countries such as Canada, United States of America, United Kingdom and Europe. Travellers should follow recommendations to avoid mosquito bites when travelling in overseas countries where there is a risk of any mosquito-borne disease. This is particularly important if a woman is pregnant or likely to become so. The Department of Health is also issuing advice to clinicians to raise awareness of the need to consider Zika virus infection in travellers returning from affected areas. The department is working closely with colleagues in the states and territories through the Communicable Diseases Network Australia to ensure a national approach. Australian laboratories are able to diagnose Zika virus infection if required. Zika virus infection is nationally notifiable. There have only ever been 20 confirmed cases reported in Australia, all of whom were infected overseas. There is a very low risk of transmission of Zika virus in Australia, due to the absence of the mosquito vectors in most parts of the country. The mosquitos that can transmit Zika virus are present in Central and North Queensland, but there is no evidence that Zika has been transmitted in Australia. In the event of an imported case in areas of Queensland where the mosquito vector is present, health authorities will respond urgently to prevent transmission, e.g. as they do for dengue. There is no vaccine or treatment for this virus. Prevention by avoiding mosquito bites is the best course of action. BACKGROUND Zika virus is closely related to the dengue virus. It is spread through the bite of an infected mosquito, specifically the dengue mosquito Aedes aegypti,and also some other Aedes species. In Brazil, 150 to 200 cases of microcephaly (small brain) have been reported in new born babies each year from 2010 to 2014. In 2015, there was a sharp increase to 739 cases as of 21 November 2015. This increase occurred concurrently with the reported outbreaks of Zika virus infection in 18 Brazilian states. Zika virus can be found in animals in many parts of Asia and Africa without any outbreaks in humans. Outbreaks of Zika virus infection were reported in the Pacific in 2013 and 2014, and more recently in South and Central America in 2015, continuing into 2016. Zika virus spread rapidly amongst humans through South and Central America in 2015 and early 2016, with the list of countries in the region that are affected continuing to grow. If someone has caught Zika virus it can take up to 12 days for symptoms to appear. Only one person in five who becomes infected is likely to have any symptoms, and if they do, the disease is generally not severe and lasts only a few days. Symptoms typically include a fever, pain in the joints, especially in the hands and feet with swelling, muscle pain, headache, with pain behind the eyes, conjunctivitis, a skin rash and weakness or lack of energy