EMERGING PANDEMIC THREATS (EPT) PROGRAM Overview Indonesia is situated in a hot spot region for emerging and re-emerging infectious diseases due to the climate, biodiversity, and close interaction of people and wildlife. Additionally potential drivers or emerging pandemic disease, such as population pressures, changing habitats, economic growth, food security, and globalization, exist in Indonesia. The EPT Program launched in Indonesia in July 2011 and is part of a commitment by the U.S. Agency for International Development (USAID) to preempt or combat newly emerging diseases that could spark future pandemics. Strategy Nearly 75 percent of all new emerging or re-emerging pandemic diseases affecting human at the beginning of the 21st century have originated in animals. The EPT program therefore emphasizes early identification of and response to dangerous pathogens in animals before they can become significant threats to human health. Key projects of the EPT Program are: PREDICT, RESPOND, IDENTIFY, and PREVENT. Consumption of wild birds or other bush meat is a common practice for communities who live close to the forest. This is a potential route for emerging infectious disease transmission from animals to humans (Photo: PREDICT Document) PREDICT Through PREDICT, USAID, international and national partners increase local capacities in hot-spot area to identify the emergence of new infectious diseases in highrisk wildlife such as non-human primates, bats, and rodents that could pose a major threat to human health. In Indonesia, PREDICT, coordinated by the Director of the Primate Research Center at Bogor Agricultural University (PRC-IPB), and involves Ministry of Health (MOH), Ministry of Agriculture (MOA), Ministry of Forestry (MOF), Eijkman Institute for Molecular Biology, the Indonesian National Institute of Science (LIPI), the National Committee on Zoonosis Control, and several universities. In order to strengthen and improve lab system for sample analysis, PREDICT Indonesia conducted it's first large scale wildlife sampling in the National Park and markets in Northern Sulawesi. Samples were collected from bats and rats and are now being tested at IPB for a range of emerging virus families. Testing of human samples from cases of fever of unknown origin is underway at the Eijkman Institute of Molecular Biology to look for the presence of and changes in viral families known to jump from animals to humans. The Eijkman Institute opened a new Emerging and Arbovirus Research Laboratory in early 2013 with support of PREDICT and CDC. RESPOND This project focuses on Indonesian institutions including universities to strengthen their capacities to prepare cadres of professional to identify and respond to outbreaks of newly emergent diseases in a timely and sustainable manner. Indonesian One Health University Network (INDOHUN) meeting. INDONHUN is a network of academics (faculties of medicine, public health, veterinary medicine, and nursing), professional associations, and government services who seek to strengthen Indonesia’s capacity to identify and respond to outbreaks of emerging and remerging diseases (Photo: USAID Indonesia EPT Program Document) Indonesia currently chairs the South East Asia One Health University Network (SEAOHUN) which is a partnership of universities in Indonesia, Vietnam, Malaysia, and Thailand to promote and advance the One Health approach for control of emerging and re-emerging infectious and zoonotic diseases in this Asian region. Indonesia One Health University Network (INDOHUN) is *February 2013 a nationwide effort of 16 universities to establish a network to strengthen Indonesia’s capacity to identify and respond to outbreaks of emergent diseases quickly and effectively through integrated curriculum development, surveillance, and outbreak response. The RESPOND Project supported the Sixth TEPHINET Southeast Asia and Western Pacific Bi-regional Scientific Conference which was hosted by the Government of Indonesia in Bali, on November 2011. This forum facilitated scientific exchange on key public and animal health issues across the region. In collaboration with CDC Atlanta, RESPOND Project supports the Field Epidemiology Training Program (FETP) in Indonesia. An in-service training program involving PUSDIKLAT, a training center under Ministry of Health (MOH) or Ministry of Agriculture (MOA), will be established to institutionalize surveillance and outbreak response capacity building, especially for the government field officers and forest rangers. This will be conducted in South Sulawesi partnering with Australian Agency for International Development (AusAID). the way people live and their practices to develop interventions to be shared with governments, NGOs and other stakeholders. PREVENT undertakes research to better understand risks associated with legal and illegal trade in key species of wild animals and mitigate risks. Extractive industries represent an important driver of potential emerging pandemic threats through land-use and human settlement changes that increase humananimal contacts. PREVENT is working with representatives of industry and finance to prevent or mitigate the risks associated with land use and population changes arising from extractive industry activities. PREVENT will undertake research to characterize possible risks and local staff are being hired. A desk study looking at extractive industry, cultural and marketbased drivers, in these designed geographic areas, has been completed. PREVENT will expand explorations of program and policy options to reduce emergent risks for pandemic threats. IDENTIFY The IDENTIFY project helps enhance capacity of laboratories, in the public-health and animal-health sectors, to detect and manage emerging and zoonotic pathogens. This project is implemented by the U.N. Food and Agriculture Organization (FAO), the World Organization for Animal Health (OIE), and the U.N. World Health Organization (WHO). This project will provide sustainable inputs for: developing guidance and policy for national laboratories; promoting laboratory quality; strengthening laboratory capacity; and enhancing laboratory networking in country and regionally. Mining, logging, and plantation contribute to the local and national economic growth. On another hand, changing habitat and the ecosystem will drive new emerging and re-emerging pandemic threats (Photo: PREDICT) U.S. Centers for Disease Control & Prevention (CDC) The CDC is a key partner for the EPT program. The CDC National Center for Emerging & Zoonotic Diseases provides support to strengthen pathogen detection and discovery for arboviruses. CDC supports MOH to strengthen outbreak response and the Field Epidemiology Training Program. USAID-DELIVER Strengthening of laboratory networks within and across sectors along with meaningful investments in regional and national capacity building will result in more accurate and timely identification of pathogens threatening animal and human health (Photo: FAO Document) PREVENT The PREVENT project aims to increase understanding of the important drivers of emerging pandemic threats involving cultural, market-based, and major landuse/extractive industry related factors. To address the cultural drivers, PREVENT is developing tools for measuring presumptively risky exposure to animals from USAID’s existing DELIVER Project will support these EPT Projects by providing commodity procurement and logistic assistance for preparedness and response to emerging pandemic threats. Currently JSI provides support to the Ministry of Health to improve logistics and laboratory management of the influenza related surveillance network. For further information please contact: USAID Indonesia Health Office EPT Program Dr. Kendra Chittenden, email: kchittenden@usaid.gov Phone 62-21-3435-9323 *February 2013