Background Andreas Vesalius was born in December 31, 1515 at Brussells, Netherlands. When he grew up, everyone expected him to work in the field of medicine: it ran through the family, they told him. After all, his grandfather was the personal doctor of the Holy Roman Emperor, Maximilian I and his father served the Emperor as well then went on to work at an apothecary. His father (Andries von Wessell) went to serve Maximilian’s successor, Charles V, later on. Medical Studies and Discoveries At 1532, he went to Paris to study medicine at the University. His teachers taught the students about Cladius Galen’s ideas about the human body. The teachers also taught the students about the human anatomy by carving up animal bodies. This method, however, failed to show what the skeletal structure looked like (obviously, animals don’t have the same body structure as humans.) Why didn’t they butcher human corpses instead is due to the fact that the Roman Catholic Church was in its prime and that carving up human bodies was against their law. Doing so could result in execution by burning at stake. Vesalius still wanted to see for himself how the body looked like. He also wanted to do the dissections himself so he can see what things did the teachers missed. So, a local magistrate helped him by handing over the bodies of executed criminals. He then went on to disprove Galen’s theories of the body. For example, Galen stated that the human jaw contained two bones when Vesalius proved that there was only one. However, there was tension between Charles V, the Holy Roman Emperor, and Francis I, king of France. On the eve of Vesalius’s graduation, Charles V decided to attack his bitter rival. Vesalius had to choose his side: choosing France meant betraying his father, choosing the Holy Roman Empire meant quitting his studies. He chose to join Charles V. Vesalius left France and continued studying. There, he conducted the dissecting himself: this time on corpses of criminals provided by a kind, local magistrate. He then went on to disprove Galen’s theories of the body. For example, Galen stated that the human jaw contained two bones but Vesalius proved that there was only one. Of course, he couldn’t keep all these information to himself; he had to share it somehow… On the Fabric of the Human Body In 1543, Vesalius went to Switzerland to ask the best publisher by then to help him compile his book which he titled ‘De Humani Corporis Fabrica’ or, in English, ‘On the Fabric of the Human Body.’ The book, which contained seven volumes, was designed to show Galen’s inaccuracies and portray the entire human anatomy in its entire splendour. His Findings and Discoveries Vesalius’s findings on the human body changed what people thought by then. Claudius Galen, who did not perform experiments on an actual human specimen, based his findings on that of the structure of an animal’s body. Since Vesalius experimented on human corpses, he was able to find out what Galen’s mistakes and inaccuracies were and correct them. Also, since Galen experimented on animals instead of human bodies, there were, of course, a lot of mistakes. Vesalius’s discoveries were many and will be explored in depth. System Galen’s Observation Vesalius’s Findings Skeletal System The jaw contained two bones The jaw contained a single bone The skeleton is the framework of every body. The sternum contained three bones The sternum contained seven bones Cardiac System Nervous System Digestive System Water is able to pass through the septum that separates the left and right ventricles in the heart Everyone has (on average) the same amount of ribs and that the idea that females have one more rib bone is false The fibula and tibia are larger than the humerus bone in the arm The septum is waterproof and the mitral valve blocks the passage between the two ventricles He discovered the canal that, through the vena cavae and the umbilical cord, passes through the unborn baby He stated that the heart is not a true muscle since its movements are involuntary He discovered two chambers and atria He believed the nerves are connected to the brain and not to the heart Contrary to belief by then, Vesalius stated that nerves were not hollow Vesalius said that the kidneys filtered blood and waste products He described the connections of the stomach and spleen to the omentum Other Notes Galen got his idea from the fact that apes have seven bones in their sternum It was Vesalius who discovered the mitral valve and he was also the same person to name it By then, people thought ligaments and tendons were all nerves People by then thought that the kidneys filtered urine and that one of them was higher than the other Habits of Mind used: Taking Responsible Risks- Cutting up corpses was considered sacrilege and was punishable by death. Vesalius knew this but he also knew that his discoveries could (and it really did) have a major impact on the world. Persisting- Charles V’s invasion of France during his graduation did not stop the maverick from discovering great things. Also, the fact that only the teachers were allowed to dissect specimens did not put Vesalius off. Striving for Accuracy- Vesalius tried to be as accurate as possible in his findings by performing the experiments himself and on real human corpses instead of animals. Processes Vesalius went through: 1. 2. 3. 4. Vesalius went to university in Paris. Afterwards, he was forced to move out to join Charles V against Francis I. He then went on to Italy to start studying the human body. He performed experiments on human specimens provided by a local magistrate to help him disprove Claudius Galen’s ideas and theories. After discovering as much as he can, Vesalius went to Switzerland to ask the best publisher in that time to help him compile his book. He even carried the notes himself when he was about to pass through a narrow pass in the Pyrenees mountains. When the book was published, he released it to the public and convinced them that Galen’s ideas about the human body were wrong. Barriers: 1. 2. 3. 4. The teachers were a barrier in that they do the experiments themselves and do not give the students a chance to learn for themselves. Galen’s ideas were thought to by all to be true and were rarely corrected. This had a psychological impact in the sense of the world around Vesalius telling him that all he was doing was in vain since he wouldn’t discover anything new; Galen had stated everything. The Roman Catholic Church was a barrier by preventing the surgeons experiment on human bodies. Thus, Vesalius had to find a way to perform his slicing and cutting on real human corpses. Charles V’s invasion of France prevented Vesalius from completing his studies.