MILK SA: R & D FIVE-YEAR PLAN [AN OUTLOOK TOWARDS 2020]. Project PRJ-0080 Report July-Sept 2015. Compiled by Programme Manager: R & D. 1. POINT OF DEPARTURE: 1.1. Statutory resolution: “To give effect to the purpose of designated levies to R & D as per Regulation R57 of 30 January 2009, which states: “Research and development are required to promote not only the viability of the dairy industry but also to promote the achievement of the other objectives of the Act as set out in section 2 (2) of the Act: Research is fragmented and action is required to ensure coordination and that research and development are functional in respect of the strategic direction of the industry, namely broadening of the market for milk and other dairy products, improvement of the international competitiveness of the South African industry, and empowerment of previously disadvantaged individuals. Furthermore, action is required to promote the practical application of local and international research and development in South Africa”. 1.2. Application: R & D in practice will address primarily national and international competitiveness, since broadening of the market and empowerment of the previously disadvantaged heavily rely on respectively, promotion and consumer education and training and extension. This does not exclude R & D, but prioritised projects are expected to be rare. R & D to increase competitiveness must address a demonstrable problem, risk or need which impacts on profitability, sustainability and continuous improvement of the dairy industry. Therefore the R & D must be solution focussed, which makes arguments about applied versus fundamental or basic mostly irrelevant. 2. R & D FIELDS IDENTIFIED AND STRUCTURAL ARRANGEMENTS: The fields identified at R & D Forum Meetings in 2010/2011 and subsequently adapted are: - Feed sources and animal nutrition - Dairy products and nutraceuticals - Genetics, physiology and reproduction - The environment - Markets and techno-economics - Animal health, bio-security and welfare. - Food safety and quality Details of priority subjects of the field are in Annexure 1. The Research Project Evaluation Committee (RPEC) has access to expertise associated with the fields for guidance and advice (also in Annexure 1). A National Producer Work Group feeds in demonstrable problems/needs to the RPEC, as provided by similar constructed provincial work groups, for evaluation and allocation to suitable expertise and capacities to be developed into R & D protocols where appropriate. Through networking and official agreements, such as MoA’s with provinces and the ARC and the SESCORD initiative, their R & D agendas are aligned to the national goals and objectives of the industry. In terms of funding, the agreements allow access to government funds, in addition to strengthening the possibility of obtaining access to dedicated funding sources as made available by DAFF, DTI and DST and administered by the NRF. This may contribute significantly towards supplementing a comparatively low levy allocation to R & D, thereby supporting a sustainable R & D programme. The network requires continuous strengthening towards 2020 to ensure effective service to the industry. 3. R & D FIELDS SERVICED BY CURRENT PROJECTS: 3.1. Animal health, bio-security and welfare: 3.1.1. Fasciolosis (liver fluke) – Project by UP (Onderstepoort) started in 2015 and is envisaged to be completed in 2017. Title: Fasciola hepatica: Impact on dairy production and sustainable management on selected farms in South Africa. Project leader: Dr Jan van Wyk, BVSc. Total budget: R967 626 (2015 – R701 183; 2016 – R266 443) Objectives in brief: Investigation of prevalence, seasonal cycling, mode of transmission of the parasite and management programmes followed by farmers, and in addition, anthelminthic efficacy. Comment: Project continuation/direction in second year will depend on results obtained in first year. 3.1.2. Mastitis 3.1.2.1. Project by UP (Onderstepoort) started in 2015 and is envisaged to be completed in 2018. Title: Resistance to available antibiotics in lactating cows with mastitis. Project leader: Dr Martin van der Leek, BVSc, MS Total budget: R1 391 500 (2015 – R514 616; 2016 – R561 184; 2017 – R315 700). Objectives in brief: Characterization and prevalence of mastitis-causing organisms, testing in vitro sensitivity of the organisms, establishing antibiotic resistance and observing mastitis management programmes on farms. Comment: Project continuation/direction in subsequent years will depend on results obtained in first year. 3.1.2.2 Project by UKZN (Plant Pathology) started in 2013; involvement by Milk SA from 2015 and is envisaged to be completed in 2018. Title: Investigating alternative methods such as bacteriophages and bacteriocins to control mastitis organisms. Project leader: Prof Mike Laing, PhD Total budget: R2 352 891 (2015 – R771 294; 2016 – R761 355; 2017 – R 820 242). Objectives in brief: Classify and determine efficacy of bacteriophages against Staphylococcus aureus; isolate bacteriocins from Staphylococcal and Streptococcal strains; do in vitro screening and efficacy tests; test promising isolates in vivo; develop commercial products. Comments: Promising bacteriophage isolates were identified in a PhD study (Iona Basdew) in 2013. These are further challenged and quality control done in 2015; other possibilities are investigated to develop a mix to facilitate non-adaptation by mastitis pathogens. 3.1.3. Disease monitoring – Project by Veterinary Network (V-Net), started in 2014, is envisaged to continue for a number of years, but will be evaluated annually. Title: National disease monitoring and extension system for the Dairy Industry. Project leader: Dr Danie Odendaal, BVSc Total budget: R394 000 for 2015 Objectives in brief: Outbreaks and general occurrence of diseases are monitored throughout the country with the aid of some 120 private veterinarians; a report programme is developed to facilitate timely report and reaction; application to cell phone is investigated. Comments: Success and application methodology are evaluated every year to determine continuation, efficacy and development of adapted or new methodology. 3.2. Food safety and quality Microbial contamination of milk – Project by UP (Main Campus), started in 2013 and completed in 2015. Title: Characterization of coliform bacteria and Escherichia coli from retail bulk milk to determine the prevalence of possible pathogenic types. Project leader: Prof Elna Buys, PhD. Total budget: R100 000. Objectives in brief: Characterization of colifoms; pathogenic and commensal E.coli for relatedness of strains from various strains, their virulence and antibiotic resistance. Comments: The project is in the final stages of completion; there remains an objective of stochastic modelling, but this will be determined by requirements of the Dairy Standards Agency (DSA) which initially expressed the need for the project. The DSA has also requested a detailed report for submission to the Department of Health. 4. PROJECTS SUPPORTED WITH NO DIRECT FINANCIAL OBLIGATIONS: 4.1. Döhne, Eastern Cape – Low-input (Once-a-day-milking), as model for emerging farmers and a Livestock Development Project 4.2. Elsenburg and other stations, Western Cape – Silage potential of small grains, legumes and within intercropping systems for milk production. 4.3. Fort Hare – Animal welfare studies at Amadlelo facilities. 4.4. Fort Hare/Döhne – Benchmark project for milk production for emerging farmers in the Eastern Cape. 5. R & D PROGRAMMES IN PROCESS OR TENTATIVELY APPROVED: 5.1. Feed sources and animal nutrition, plus Food safety and quality: 5.1.1. Milk flocculation: 5.1.1.1. The effect of cow nutrition on milk flocculation 5.1.1.2. The significance of proteolytic psyghrotrophs as a cause of milk flocculation/protein instability 5.1.1.3. The impact of proteases and chemicals on milk flocculation Comments: The programme has already been accepted; anticipated date of commencement is 2016; projects 5.1.1.2 and 5.1.1.3 may be consolidated as they may portray sequential events in the milk collection line. 5.2. Genetics, Physiology and Reproduction: 5.2.1. Genetic and performance monitoring: Motivation: The Dairy Industry must support and encourage progress in the SA Dairy Herd in terms of output, efficiency and economic sustainability. The proposal is to consider a genetic improvement/performance programme with development and ownership of an extensive database that include automated systems, in addition to milk recording data (where appropriate). Furthermore, it is proposed to eventually link the genetic improvement/performance programme with the National Disease Monitoring and Extension programme. With comparatively low cost interface development in the Logiχ system, the data sets can be linked with even more benefits to the individual farmer as well as the National Herd. Nature of project: Statistical trend monitoring of participating farmer results over time to establish progress of critical indicators. Anticipated date: 2016, long term, but evaluated annually. 5.2.2. Selection based on Residual Feed Intake (RFI): Motivation: Using this method, heifers within large herds can be selected on growth rate that will carry through to milk production. This will reduce rearing cost and identify efficient replacements. If cows are selected on this basis, it will improve the feed/milk ratio. Additional merit is RFI is repeatable on different diets, it is robust, cows with lower intake have lower GHG emissions and they show improved immunity. Nature of project: Demonstrations and monitoring on farm. Anticipated date: 2016, open-ended. 5.3. Animal health, bio-security and welfare: 5.3.1. Programme: Biological control of Fasciola and nematodes 5.3.1.1. Project proposal: UKZN (Plant Pathology) Project leader: Prof Mark Laing, PhD Project title: Integrated control of Fasciolosis of livestock. Budget: R300 000 per year for 3 years. Comments: Application to Research & Technology Fund of the DAFF at NRF; commencement date 2016; funding specifications indicate a 4:1 ratio between RTF and industry partner (Milk SA). 6. PROPOSALS TOWARDS 2020: 6.1. Animal health, bio-security and welfare: 6.1.1. Mastitis: The disease should be addressed from different angles. 6.1.1.1. From the results of item 3.1.2.1., the pathogens dominant in specific areas should be known. This may allow R & D associated with vaccine development, either through local testing of imported vaccines or via own R & D. 6.1.1.2. Genetic progress against the disease may be obtained through crossbreeding, or preferably within breed using genomic/SNP analysis. 6.1.2. National Disease Monitoring and Extension Programme: A value-adding development could be development of rapid on-site diagnostic tools. Such equipment and identification methodology (e.g. for FMD and RVF) have been developed by Bio-Sciences of the CSIR in association with Australia’s CSIRO. This should be further investigated. 6.1.3. Lameness: The condition is one of the most devastating and costly, and often neglected by farmers. Farmers may lose up to one-third of the milk yield of an affected cow. It is also a serious animal welfare issue and therefore the Dairy Industry should be seen to do work in this area, even though there are many programmes elsewhere in the world. 6.2. Environment: 6.2.1. Pasture establishment in the south-eastern seaboard: Monoculture pasture species has implications for bio-diversity, ecosystems, eutrophication and water sources. Heavy fertilization and cattle manure may also cause pollution. Outeniqua Research Station has a R & D and monitoring programme. It is important that this programme continue and it should be promoted through the SESCORD initiative. Item 6.3.1. is important here. 6.2.2. Carbon and water footprint: Although figures and knowledge are mostly available, the DEA is required to report regularly to the IPCC on mitigation, which requires updated figures. The envisaged government pressure which may lead to taxation could require actual measurements to demonstrate decreasing trends. This may also require an inventory and documentation. Outeniqua Research Station has capacity to measure GHG and such work there should be supported. 6.3. Feed sources and animal nutrition: 6.3.1. Pasture cultivar testing/selection: The ARC facility at Cedara is expected to be revived and programmes resumed. Outeniqua is expected to continue. SESCORD should provide guidance. 6.3.2. Forage and roughage sources: For pastures Item 6.3.1. is important. Sustainable establishment, evaluation and improvement of forage sources and storage as quality silage and hay sources should always be considered. 6.3.3. Concentrate supplementation: Supplements are expensive and the inclusion of less-starch concentrate feed sources that could improve cost effectiveness must be encouraged, also to combat the continuous burden of sub-clinical acidosis (both in TMR and pasture-based systems). 6.4. Dairy products and nutraceuticals: 6.4.1. New products to support patients: HIV/AIDS and cancer treatment has major implications, amongst others Candida albicans infections. Treatment with antibiotics have limitations. If products containing probiotics can be developed instead, which can be used regularly candida infections can be prevented. Probiotic strains that are effective have already been selected and effectively incorporated in a maize-based drink at the TUT. Indications are that a milk or milk-product substrate could be as or more effective which makes such a possibility an attractive proposition. Irrespective of the viability and impact on broadening of the market, it is important that the Dairy Industry is seen to make a contribution to the well-being of patients and communities at large. 6.5. Food safety and quality: 6.5.1. Preventing/removing biofilms in milk lines: Bioflim and spore-forming organisms are implied in unsatisfactory shelflife of longlife milk. They are also associated with mastitis-causing pathogens and because of protease activity with the enormous problem of milk flocculation. Biofilms are traditionally removed with sanitizers or with steam sterilization, UV and hydrogen peroxide depending on position in the milk line, structure of equipment and practicality. Biofilm formation and spore-forming organisms are increasing, which indicates that current methods and probably sanitizers on the market are less effective. Therefore new/other sanitizers and alternative methods should be considered.