BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors.
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NAME
POSITION TITLE
Nina L Suresh, Ph.D.
INSTITUTION AND LOCATION
Research Scientist
Sensory Motor Performance Program (SMPP)
DEGREE
(if applicable)
FIELD OF STUDY
University of Illinois Chicago, IL
B. S. (summa
cum laude)
Mathematics and Computer Science
University of Illinois Chicago, IL
Ph.D.
Biomedical Engineering
Other Experience and Professional Memberships
Member, Society for Neuroscience
Member, IEEE Engineering in Medicine and Biology Society
Honors
Outstanding Young Women of America
NRSA Fellowship
NIH
1987
1999-2002
Peer-reviewed Publications
Hu X, Rymer WZ, Suresh NL Motor Unit Firing Rate Patterns During Voluntary Muscle Force
Generation: A Simulation Study. J of Neural Eng [In Press].
Miller DM, Klein CS, Suresh NL and WZ Rymer Asymmetries in vestibular evoked myogenic
potentials in chronic stroke survivors with spastic hypertonia: evidence for a vestibulospinal role. Clin
Neurophysiol [In press].
Chardon MK, Rymer WZ, and NL Suresh Quantifying the Deep Tendon Reflex Using Varying
Tendon Indentation Depths: Applications to Spasticity IEEE Trans on Neural Systems Rehabil Eng [
In press].
Mottram CJ, Heckman CJ, Powers RK, Rymer WZ and Suresh NL Disturbances of Motor Unit Rate
Modulation are Prevalent in Muscles of Spastic-Paretic Stroke Survivors. J Neurophysiol. 2014 Feb.
Hu X, Rymer WZ, Suresh NL. Accuracy assessment of a surface electromyogram decomposition
system in human first dorsal interosseus muscle. J Neural Eng. Feb 21;11(2) 2014.
Hu X, Rymer WZ, Suresh NL Assessment of validity of a high-yield surface electromyogram
decomposition. J of Neuroeng and Rehabil 10 (99), 2013. PMID: 24059856
Hu X, Rymer WZ, Suresh NL Reliability of spike triggered averaging of the surface electromyogram
for motor unit action potential estimation. Muscle and Nerve 48: 557-570, 2013. PMID: 23424086
Hu X, Rymer WZ, Suresh NL Motor unit pool organization examined via spike triggered averaging of
the surface electromygram. Journal of Neurophysiology 110: 1205-1220, 2013. PMID: 23699053
Li X, Wang Y, Suresh NL, Rymer WZ, Zhou P. Motor unit number reductions in paretic muscles of
stroke survivors. IEEE Transactions on Information Technology in Biomedicine 15(4): 505-12, 2011.
PMID: 21478079
Zhou P, Suresh NL, Lowery M, and Rymer WZ. Nonlinear filtering of multi-channel EMG signals at
low muscle contraction levels. IEEE Transactions on Biomedical Engineering 56(7): 1871-1879,
2009. PMID: 19342344
Zhou P, Suresh NL and Rymer WZ. Model based sensitivity analysis of EMG-Force relation with
respect to motor unit properties: Applications to Muscle Paresis in Stroke. Annals of Biomedical
Engineering 35(9): 1521-1531, 2007. PMID: 17530407
Zhou P, Suresh NL and Rymer WZ. Surface electromyogram analysis of the direction of isometric
torque generation by the first dorsal interosseous muscle. Journal of Neural Engineering 8(3):1-10,
2011. PMID: 21566274
Mottram CJ, Suresh NL, Heckman CJ, Gorassini MA and Rymer WZ. Origins of abnormal excitability
in biceps brachii motoneurons of spastic-paretic stroke survivors. Journal of Neurophysiology 102:
2026-2038, 2009. PMID: 19587321
Kutch JJ, Suresh NL, Bloch A, Rymer WZ. Analysis of the effects of firing rate and synchronization on
spike-triggered averaging of multidirectional motor unit torque. Journal of Computational
Neuroscience 22:347-361, 2007. PMID: 17377834
Suresh NL, Ellis MD, Moore J, Heckman H, and Rymer WZ. Excitatory synaptic potentials in spastic
human motoneurons have a short rise-time. Muscle Nerve 32: 99-103, 2005. PMID: 15786417
Additional recent publications (in chronological order)
Suresh NL, Zhou P, Rymer WZ. Abnormal EMG-force slope estimates in the first dorsal interosseous
of hemiparetic stroke survivors. Conf Proc IEEE Eng Med Biol Soc. 1:3562-5, 2008. PMID: 19163478
Murali K, Suresh NL, Stiller R, Rymer WZ, and Zhou P. Analysis of EMG-force relation of the first
dorsal interosseous muscle using an electrode array. Conf Proc IEEE Eng Med Biol Soc. 1:2960-2,
2009. PMID: 19963546
Schieber JR, Suresh NL, Rymer WZ, and Zhou P. A preliminary study of action potential
propagation in paretic muscle of stroke survivors. Conf Proc IEEE Eng Med Biol Soc.1:222-3, 2009.
PMID: 19964733
Chardon MK, Suresh NL and Rymer WZ. A new method for reflex threshold estimation in spastic
muscle. Conf Proc IEEE Eng Med Biol Soc. 1:5300-3, 2009. PMID: 19964120
Chardon MK, Suresh NL and Rymer WZ. An evaluation of passive properties of spastic muscles in
hemiparetic stroke survivors. Conf Proc IEEE Eng Med Biol Soc. 2010: 2993-6, 2010. PMID:
21095718
Suresh NL, Wang I, Heckman CJ and Rymer WZ. Characterization of the tendon vibration reflex
response in hemi-spastic stroke individuals. Proc IEEE Eng Med Biol Soc. 2011;2011:2053-6. PMID:
22254740
Suresh NL, Li X, Zhou P, Rymer WZ. Examination of Motor Unit Control Properties in Stroke
Survivors Using Surface EMG Decomposition: A Preliminary Report. Proc IEEE Eng Med Biol
Soc.;2011:8243-6. PMID: 22256256
Hu X, Suresh, AK, Li X, Rymer W Z and Suresh, N L. Impaired motor unit control in paretic muscle
post stroke assessed using surface electromyography: A preliminary report. Conference Proceedings
of IEEE Engineering in Medicine and Biology Society, 2012: 4116-4119. PMID: 23366833
Suresh NL, Kuo A, Heckman CJ and Rymer WZ Using spike-triggered averaging to characterize
motor unit twitch vectors in the first dorsal interosseous. Proc IEEE Eng Med Biol Soc.
2012;2012:3604-7.
Patents
Patent Pending for TnS, a simple device to quantify measurements in spasticity. (U.S. Provisional
Application entitled, “Method For Reflex Threshold Estimation in Spastic Muscles” filed with Matthieu
K Chardon, W Zev Rymer and Nina L Suresh.)
Invited talks/presentations:
6th Annual Reflex Plasticity Meeting SFN ( Society for Neuroscience) reflex meeting; November 12,
2013, “Anomalous EMG-Force relations during stretch reflex responses in stroke survivors.”
XIX Congress of the International Society of Electrophysiology and Kinesiology
ISEK 2012 18 July 2012, Brisbane, Australia Pre-conference workshop: Using surface EMG for
motor unit analysis: From understanding motor disorders to clinical applications
First International Symposium on Movement Science: Motor Control, Biomechanics and Physiology.
Santiago, Chile; April 20 2012 Talk: “The use of EMG assessments to characterize
motoneuronal properties in stroke.”
First International Symposium on Movement Science: Motor Control, Biomechanics and Physiology.
Santiago, Chile; April 21 2012 Workshop: “Using EMGs for motor unit analysis: From
understanding motor disorders to clinical applications. “
XIX Congress of the International Society of Electrophysiology and Kinesiology
ISEK 2012 18 July 2012, Brisbane, Australia Pre-conference workshop: “Using surface EMG for
motor unit analysis: From understanding motor disorders to clinical applications.”
Clinical Research Grand Rounds at the Rehabilitation Institute of Chicago; April 9, 2012 “ Skimming
the surface: from EMG to motoneuron function”.
Clinical Research Grand Rounds at the Rehabilitation Institute of Chicago; May 9, 2011 “Tapping
into Spasticity”.
Mentored Colleagues
September 2011-March 2013
Postdoctoral Fellow: Xiaogang Hu
June 2012 – December 2012
Under graduate thesis: Andres Cardona
Escuela de Ingeniería de Antioquia
Biomedical/Mechatronics Engineering
September 2007- present
PhD Student: Matthieu Chardon
Dept. of Biomedical Engineering(BME), Northwestern University
(Co-mentor with WZ Rymer)
June 2013 – present
PhD Student: Rony Silvestre
University de Los Andes Santiago Chile
(Co-mentor with WZ Rymer)
June 2012 – present
Undergraduate Student: Brian Jeon
(B.S. in BME/EE, Johns Hopkins University)
June 2011 – present
Undergraduate Student: Sudarshan Srivatsan
(B.S. in (BME), Northwestern University)
June 2013 - December 2013
Henry Shin
(Co-op student MS/BS BME, Northwestern University)