IC-102: Strategies for Very Dense Nuclei and other Challenging & Complicated cases; a Video Course Micro-coaxial Torsional Phaco for challenging cases; Tips & Settings Khiun Tjia MD Intrepid FMS The Intrepid FMS® has a significant lower compliance tubing than the original FMS. Contraction/expansion of aspiration tubing in response to (high vacuum) occlusion break is a main contributor to surge flow. Surge flow is the main cause of anterior chamber instability. It is therefore very logical to minimize surge flow by reducing the compliance of the aspiration tubing. With Intrepid FMS, surge flow volume on occlusion break is significantly lower than with the original FMS. At the moderately high vacuum levels 300Hg currently used with Torsional ultrasound, the surge flow volume is extremely low with Intrepid FMS, resulting in very good anterior chamber stability and a further increased margin of safety. The use of Intrepid FMS is highly recommendable in complicated phaco surgery Very dense and hard nuclei Tip choice for Torsional ultrasound and Dense nuclei For very dense nuclei, 45º bevel tips are more efficient compared to 30º bevel tips. The 45º tips have a larger surface and make the nuclear pieces tumble around their axis whilst being emulsified. 30º tips drill more easily into the nucleus (lollipop) and emulsification halts when the sleeve obstructs further movement. Our experience with Traditional Longitudinal ultrasound and very dense nuclei is that Flared Tip designs were prone to potential clogging of the tip. Clogging of a tip could lead to insufficient cooling of the tip and possible heating / burn of the corneal tunnel. Because of the sideways ultrasonic movement of a tip with Torsional ultrasound, the nucleus is emulsified in a different manner. The nuclear material at the tip and inside of a flared phaco tip is probably less emulsified compared to Longitudinal ultrasound. There is also no significant repulsion and subsequent repositioning of the nucleus relative to the tip. This could be an explanation for the higher incidence of clogging of Flared Tip designs with Torsional ultrasound. If a surgeon still prefers to work with a 45 miniflared tip, a high minimum amplitude of about 60-70% (software 2.03 version) should be used or a mix of longitudinal and torsional ultrasound to reduce the potential for clogging of the tip. A Tapered Tip design rarely clogs, even with dark brown nuclei. Microtip has identical dimensions from Tip end to Tip shaft and has theoretically no chance for clogging at all. Personally, I prefer to use a 45 Kelman Micro Tip for cataract cases with very dense nuclei. Cataracts with less nuclear density can also be handled with Mini Flared Tips. In the rare case of a sign of stalling or clogging of a Mini Flared tip, I use a mix of Torsional and Longitudinal ultrasound , which I have preset in a separate grade. OZil IP Software In September 2009, a software upgrade was released. OZil IP software allows the user to momentarily supplement torsional amplitude with very brief bursts of longitudinal ultrasound when a programmable vacuum threshold is exceeded. These short bursts of conventional ultrasound help to minimize occlusions and hence further improve fluidic stability. They also help to keep nuclear material at the ideal position of the phaco tip end, where the shaving action of torsional ultrasound occurs. The OZil IP feature can be enabled for each individual procedure step and for each cataract grade. Cracking or Chop Technique for Dense Nuclei Another challenge of handling Dense Nuclei cases is the nucleus disassembly before emulsification. Although my routine procedure still involves a modified Divide & Conquer technique (Fast Crack Phaco), I switch to a Chop technique for very dense and rubbery nuclei, which are very hard to divide in quadrants by a conventional cracking maneuver. A classic horizontal Nagahara Chop technique is a good option in my experience to chop the nucleus in multiple smaller pieces. Vertical Chop techniques are also widely used. The rounded Olson chopper combines efficacy with safety and is a very effective and easy instrument for vertical chop. Personal Settings recommendations (45 Kelman Micro Tip + Ultrasleeve) or 45 Kelman Tapered Tip: 2.2 – 2.4 mm incision for very dense nuclei Chop, for impaling and chopping the nucleus only: Bottle height : 90 cm Aspiration Flow : 25 ml/min fixed Vacuum : 500mmHg fixed Power : Burst Mode, 20msec, 50% Fixed Longitudinal US Quadrant Removal, for emulsification of the nuclear pieces: Bottle height : 90 cm Aspiration Flow : 15 ml/min linear Vacuum : 300mmHg fixed Power : Continuous mode, minimum 50% linear to maximum 100% amplitude Torsional Ultrasound Personal Settings recommendations (45 Miniflared Tip + Ultrasleeve): 2.2 – 2.4 mm incision for very dense nuclei Chop, for impaling and chopping the nucleus only: Bottle height : 90 cm Aspiration Flow : 25 ml/min fixed Vacuum : 500mmHg fixed Power : Burst Mode, 20msec, 50% Fixed Longitudinal US Quadrant Removal, for emulsification of the nuclear pieces: Bottle height : 90 cm Aspiration Flow : 15 ml/min linear Vacuum : 300mmHg fixed Power : Continuous mode, minimum 60% linear to maximum 80% amplitude Torsional Ultrasound Low Fluidics parameters strategy for Challenging Cataract surgery with Torsional Ultrasound Challenging and complicated cases like: - Zonular weakness / partial dehiscence - Posterior capsular rupture - Floppy iris syndrome - Corneal endothelial dystrophy share one common problem: Higher intracameral fluid streams have a negative effect on the outcome of these procedures. High Flow in the anterior chamber disadvantageous A high Aspiration Flow will inadvertently attract vitreous or a floppy iris to the phacotip, which can lead to further complications and potential visual loss. In endothelial dystrophy cases, high flow and turbulence in the anterior chamber will evacuate viscoelastic substances, which protect the fragile corneal endothelium from further damage by ultrasound energy. Also, the direct impact of bouncing nuclear fragments and excessive fluid turbulence by itself can also cause endothelial cell loss with subsequent corneal decompensation. High vacuum setting possibly dangerous A high vacuum setting will cause significant Surge flow on occlusion break with anterior chamber instability as a result. Such a sudden chamber pressure change can destabilize a complicated situation. (e.g. in case of a capsular rupture, nuclear pieces dropping into the vitreous or additional zonules tearing from their base in a zonular dehiscence case). Low Fluidics settings mandatory for successful outcomes Low fluid dynamics settings are mandatory for a successful outcome in these cases. A low aspiration flow of 20 ml/min or less and a low bottle height helps to prevent vitreous or iris to be caught by the phacotip. A low/moderate Vacuum setting of 200mm Hg will show no surge flow on occlusion break and less pressure variance during the procedure. In combination with the low compliance Intrepid FMS, the anterior chamber will remain very stable after occlusion break. Very low fluidics settings still very effective with Torsional ultrasound With the use of Torsional ultrasound, a very low aspiration flow setting of 20ml/min or less, a bottle height of 50 cm and a low vacuum setting of 250mmHg or less, the efficiency of Torsional ultrasound for nucleus emulsification is still amazingly good. In the case of weak zonules, a posterior capsular rupture or a floppy iris, the greatly reduced fluid turbulence will help to prevent vitreous or floppy iris to be drawn to the phacotip. A dispersive viscoelastic, which is injected to push back vitreous or iris (or to sequester a nuclear piece to prevent it from falling into the vitreous), will not be aspirated easily. In this way, a safe working distance can be maintained between the phacotip and vitreous or floppy iris. This will help the surgeon to control very difficult situations and prevent complications and the surgeon will feel much more confident in handling these complicated cases. Personal experience Posterior capsular rupture I have had to deal with remaining nuclear quadrants after an early posterior capsular rupture on several occasions. After stabilizing the situation by injecting Viscoat (Alcon laboratories) behind the nuclear pieces, I always try to bring one quadrant superior to the iris plane with a bimanual technique (Injecting Viscoat behind the piece with one hand and a second instrument for manipulation of the piece centrally and upward into a safe zone above the iris plane) I then introduce the phacotip underneath the quadrant and emulsify it very slowly and in a very controlled fashion without washing out the viscoelastic underneath. Personal Settings recommendations (MiniFlared Tip + Ultrasleeve): 2..2 mm incision for posterior capsular rupture Quadrant Removal, for emulsification of the nuclear pieces: Bottle height : 50 cm Aspiration Flow : 12 ml/min linear Vacuum : 200mmHg fixed Power : Continuous mode, minimum 35% linear to maximum 80% amplitude Torsional Ultrasound I bring every quadrant into the safe zone by injecting additional viscoelastic and emulsify them one by one without any significant fluid turbulence or pressure drops. Zonular weakness & Floppy iris For Zonular weakness and Floppy iris cases, I used similar fluidics settings to minimize fluid streams and pressure variance. I have been able to complete all procedures without any major problems. Corneal endothelial dystrophy: Use of Viscoat highly recommendable Personal Settings recommendations (MiniFlared Tip + Ultrasleeve): 2..2 mm incision for corneal endothelial dystrophy Quadrant Removal, for emulsification of the nuclear pieces: Bottle height : 75 cm Aspiration Flow : 15 ml/min linear Vacuum : 300mmHg fixed Power : Continuous mode, minimum 35% linear to maximum 80% amplitude Torsional Ultrasound At the end of quadrant removal, a thick layer of Viscoat is still visible which reassures me that the endothelial cells are protected during the entire procedure.