2. Laboratory of bioelectricity

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Attachment No 2
to Resolution of the Senate of the Wrocław Medical
University No 1441
24 September 2014
Name of
module/course
Syllabus
Part A - Description of the subject of education
Biophysics
Group of specific learning outcomes
Group code
Group name
Scientific bases of
B
medicine
Department
Field of study
Specialities
Level of study
Biophysics
Dentistry
Dentistry
Long-cycle studies X*
1st cycle 
2nd cycle 
3rd cycle 
postgraduate 
full-time X part-time 
I
Semester
mandatory X optional 
principal  basic X
Polish  English X other 
Form of studies
Year of studies
Type of course
Rank of course
Language of
instruction
* mark as appropriate changing  into X
Form of education
Lectures (WY)
Seminars (SE)
Auditorium classes (CA)
Major classes - non-clinical (CN)
Clinical classes (CK)
Laboratory classes (CL)
Specialist - master's classes (CM)
Simulated classes (CS)
Language courses (LE)
Practical classes with patient (PP)
Physical education classes - mandatory (WF)
Professional training (PZ)
Self-education
Other
Summer
Number of hours
10
35
In total 45
Educational goals:
The aim of education in the area of biophysics is understanding physical bases of processes that occur in
biological systems on the level of molecules, organelles, cells, tissues, organs and the whole human
organism. The next educational goal is understanding physical bases of modern medical diagnostic and
therapeutic methods, and some experimental methods applied in studying biological systems. During
laboratory practicals students get ability to use various equipment, perform measurements applying
spectroscopic, electrical, optical and other methods, use professional computer software and do analysis
of obtained experimental data.
Matrix of learning outcomes for module/course in relation to methods of verification of
intended learning outcomes and form of classes:
The number of
core education
outcome
The number
of major
education
outcome
Student who passes the
module/course
has the knowledge of/knows how
to/is capable of
Methods of verification of
intended learning outcomes
achievement (forming and
summary)
Form of classes
W 01
BW 4
1.Knowledge of structure
and function of important
compounds present in a
human body, in particular
of proteins and lipids and
energy production in
mitochondria.
written examination
L
BW7 ,
BW8
2.Knowledge of principles
of biomechanics and
mechanics of the organ of
mastication.
colloquium, written
examination
L, C
BW9
BW10
BW11
** enter the
symbol
3.Knowledge of physical
bases of methods of
imaging of tissues and
organs and principles of
function of diagnostic
equipment used for these
purposes.
colloquium, written
examination
4.Knowledge of principles
of function of ultrasonic
devices and their
application in diagnostics
and therapy .
colloquium, written
examination
L, C
colloquium
C
5.Knowledge of principles
of photometry and
principles of function of
waveguides and
application of light sources
in dentistry .
L, C
BW12
BW19
U 01
BU2
BU3
BU3
BU3
BU3
K 01
6.Knowledge of principles
of work of lasers and their
application in dentistry .
7.Knowledge of selected
life functions of a human
organism – physical bases
of function of nerve
system, circulatory system
and function of selected
sensory organs .
1.Ability of interpretation
of physical phenomena in a
human organism, in
particular, in the organ of
mastication .
written examination
L
colloquium, written
examination
L, C
2.Ability of application of
proper methods of imaging
diagnostics in work of a
dentist.
3.Ability of application of
ultrasounds in work of a
dentist.
4.Ability of application of
properly-selected laser
light in a clinical practice.
5.Ability of application of
ionising radiation and
ability of estimation of a
irradiation risk in a dentical
practice.
Students actively
participate in a team work,
are creative, think logically
and independently, learn
to face challenges and are
interested in selfeducation.
**WY - lecture; SE - seminar (SE); auditorium classes - CA; CN - principal classes (non-clinical); CL - laboratory classes; CN specialist (master's) classes; CS - simulated classes; LE - language courses; PP - practical classes with patient; WF - physical
education classes (mandatory); PZ - professional training; SK - self-education
Put a cross on a 1 to 3 scale to mark how the above outcomes categorize your classes in terms
of knowledge, skills and attitudes e.g.:
Knowledge + + +
Skills + ++
Attitudes +++
Student's workload (the ECTS credit balance):
Form of student's workload
Student's workload (h)
(attendance, initiative, preparation to classes,
45
verification etc.)
1. Contact hours
5
2. Time dedicated to student's own work
40
Total student's workload
90
The ECTS credits per module/subject
5
Remarks
Classes content: (please put down the classes subject matter in a concise form with the consideration of the form of
classes and bearing in mind the fact that the subject matter should translate into the intended learning outcomes)
Lectures
1. Physical aspects of membrane transport of substances and signal transduction.
2. Principles of electrophysiology – nerve impulse, neuromuscular transmission, muscle
contraction.
3. Biophysics of systems and sensory organs.
4. Introduction in a medical physics - lasers in medicine – principles of laser action, types of
lasers, waveguides, medical application. Nuclear magnetic resonance (NMR) and its
application in medicine and in biomedical sciences.
5. Influence of physical factors on a human organism.
6. Principles of biomechanics.
Seminars
1.
2.
3.
Classes
1. Laboratory of bioacoustics and biomechanics:
1.1 Ultrasonic Doppler effect
1.2 Measurements of activation threshold of an ear
1.3 Sound spectral analysis
1.4 Determination of macromolecule’s molecular weight by colloid solution viscosity
measurements
1.5 Ultrasound probe
1.6 Microcalorimetric method of investigation of phase transitions in lipids
1.7 Fundamentals of ultrasound application in medicine.
2. Laboratory of bioelectricity:
2.1 Computer simulation of action potential generation in axon
2.2 Characteristics of the Geiger-Müller counter
2.3 Estimation of the Nernst’s equilibrium potential on a ion-selective membrane
2.4 Dipolar model of a heart
2.5 Estimation of radiation attenuation coefficient
2.6 Analog model of the synaptic transmission
2.7 Nerve impulse, neuromuscular transmission, muscle contraction and its pathology
3. Laboratory of biooptics and spectroscopy:
3.1 The analysis of different emission spectra using spectroscope and monochromator.
3.2 Estimation of a colloid solution concentration using nephelometry
3.3 Fluorescence of organic dyes and its application in the quantitative luminescence analysis
3.4 Estimation of the focus length and the focus radii of the eye model
3.5 Absorption of solutions of organic dyes. Analysis of contents of a solution.
3.6 Properties of laser light and white light
3. 7 Ionising radiation and its application in medicine. Radiobiology. A physical basis of X-ray
computer tomography and positron emission tomography (PET) and application of radioactive
isotopes in imaging of tissues and organs.
Other:
1.
2.
3.
etc.
Core literature: (according to relevance, no more than three titles)
1. 1. Cotterill R. Biophysics. An introduction. J. Wiley & Sons, 2004.
2. Alberts, B., Bray,D., Lewis,J., Raff.M., Roberts,K., Watson,J.D., Molecular Biology of the cell,
Garland Publishing, Inc., New York, 1994.
3. Kandel, E.R., Schwartz, J.H., Jessel, T.M. Principles of Neural Science, Elsevier, Amsterdam, 1991.
Supplementary literature and other aids (no more than three titles)
1. Glaser, R., Biophysics. Springer-Verlag, 2004.
2. Hille, B. Ionic Channels of Excitable Membranes, Sinauer Associates inc. Sunderland, 2004.
Requirements regarding teaching aids: (e.g. laboratory, multimedia slide projector, other)
Equipment setups for laboratory practicals in laboratories, multimedia projectors, computers, standard
and specialist software.
Initial conditions: (minimal conditions to be fulfilled be a student before signing up for the module/course)
A basic knowledge in the areas of physics, biology and chemistry
Terms of passing a given course: (please define the form and terms of passing given classes falling within the
scope of the module/course, rules for allowing students to sit final theoretical and/or practical exam, its form and
requirements that students must meet in order to pass it as well as criteria applicable to each grade)
Getting a positive note from the final written examination test after having got a credit note from
laboratory classes.
Grade:
very good
(5,0)
good plus
(4,5)
excellent
(4,0)
fairly good
Criterion for assessment: (applies only to courses/modules ending with an exam)
Giving correct answers to more than 90% of the final test questions
Giving correct answers to more than 80% of the final test questions
Giving correct answers to more than 70% of the final test questions
Giving correct answers to more than 60% of the final test questions
(3,5)
satisfactory
(3,0)
Giving correct answers to more than 50% of the final test questions
Name and address of the unit in charge of module/course, contact (phone number and email
address) ………………………
Wroclaw Medical University
Department of Biophysics,
Ul. Chałubińskiego 10
50-368 Wrocław
Tel: 71-784-14-01, e-mail: biofiz@biofiz.umed.wroc.pl
A list of persons giving particular classes including: full name, degree/academic or professional
title, field of science, profession, form of classes
Lectures and laboratory classes are given by:
dr hab. Andrzej Teisseyre – andrzej.teisseyre@umed.wroc.pl
Prepared by:
…………………………………………..
Revised by:
…………………………………………..
Signature of the Head of unit in charge of classes
…………………………………………..
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