Walkner, Renee Physiological Comp. May 1, 2011 Hallucinogens: Fact Sheet The types of drugs that cause people to have hallucinations, whether auditory or visual, are called hallucinogens. “These drugs can cause people to see and hear things that aren’t real, such as colored lights or images, strange sounds and music. Hallucinogens can also cause users to have intense mood swings, jumping back and forth between happiness, sadness, anger, depression and so on. Hallucinogens cause their effects by disrupting the interaction of nerve cells and the neurotransmitter serotonin. Distributed throughout the brain and spinal cord, the serotonin system is involved in the control of behavioral, perceptual, and regulatory systems, including mood, hunger, body temperature, sexual behavior, muscle control, and sensory perception”. (http://www.medterms.com/script/main/art.asp?articlekey=24170) Types of Hallucinogens: DMT is (found in a variety of plants and seeds; it can also be produced synthetically), LSD (the most potent hallucinogen known to man. LSD is derived from a fungus that grows on rye and other grains; however, it is also semisynthetic and is chemically manufactured in illegal laboratories. It is also the most potent hallucinogen known to man. PCP - invented as a medical anesthetic. Peyote - Mescaline is a hallucinogenic substance found within the Peyote cactus. Psilocybin - a chemical obtained from certain mushrooms found in Mexico and Central America. Street Names of Hallucinogens: DMT – “businessman’s trip” and “fantasia” LSD – “acid”, “blotter acid”, “window pane”, “dots”, “mellow yellow”, “Lucy in the sky with diamonds”, “tabs”, “paper acid”, “barrels”, “Bart Simpsons”, “Sid”, “twenty five”, “heavenly blue”, “L”, “Liquid A”, “liquid”, “mind detergent”, “microdots”, “wedding bells”, “blue unicorns”, “hits”, “orange cubes”, “sunshine”, “ticket”, and “sugar lumps”. Walkner, Renee Physiological Comp. May 1, 2011 PCP – “angel dust”, “supergrass”, “killer weed”, “embalming fluid”, and “rocket fuel”, “ozone”, and “wack” Peyote – “buttons”, “mesc”, and “peyote” Psilocybin – “magic mushrooms” and “shrooms” (http://www.pamf.org/teen/risk/drugs/hallucinogens/) Neurological effects of hallucinogens: “LSD, peyote, psilocybin, and PCP are drugs that cause hallucinations, which are profound distortions in a person’s perception of reality. Under the influence of hallucinogens, people see images, hear sounds, and feel sensations that seem real but are not. Some hallucinogens also produce rapid, intense emotional swings. LSD, peyote, and psilocybin cause their effects by initially disrupting the interaction of nerve cells and the neurotransmitter serotonin.1 Distributed throughout the brain and spinal cord, the serotonin system is involved in the control of behavioral, perceptual, and regulatory systems, including mood, hunger, body temperature, sexual behavior, muscle control, and sensory perception. On the other hand, PCP acts mainly through a type of glutamate receptor in the brain that is important for the perception of pain, responses to the environment, and learning and memory.” (http://www.nida.nih.gov/infofacts/hallucinogens.html) Physiological effects of hallucinogens: “The psychedelics are capable of producing a wide range of subjective and objective effects. However, there is apparently no reaction that is distinctive for a particular drug. Subjects are unable to distinguish among LSD, mescaline, and psilocybin when they have no prior knowledge of the identity of the drug ingested. These drugs induce a physiological response that is consistent with the type of effect expected of a central-nervous-system stimulant. Usually there is elevation of the systolic blood pressure, dilatation of the pupils, some facilitation of the spinal reflexes, and excitation of the sympathetic nervous system.” (http://www.britannica.com/EBchecked/topic/172024/drug-use/40516/Physiological-and-psychologicaleffects-of-hallucinogens) Walkner, Renee Physiological Comp. May 1, 2011 Psychedelic effects of hallucinogens: Hallucinogens are “psychedelic” drugs. “Hallucinogens, also called psychedelic drugs, create a range of perceptual distortions and various psychological symptoms. Under the influence of hallucinogens, the senses seem to be enhanced, and brilliant hallucinations occur. Many users experience synesthesia, in which various forms of hallucinations occur simultaneously. Many also describe feeling disconnected from their bodies or other altered states of reality.” (http://www.egetgoing.com/drug_rehab/hallucinogens.asp) Short term health risks from abuse of hallucinogens: Individuals who abuse hallucinogens may become delirious or psychotic. Depressive disorders often occur following the use of these substances. In a few individuals, a single, extremely frightening experience can cause severe long-term problems with a dramatic decrease in their ability to function normally. Long term health risks from abuse of hallucinogens: Long term effects include HPPD (Hallucinogen Persisting Perception Disorder), which produces repeated flashbacks to previous events. Psychosis is another long term risk. Psychosis may trigger the inability to think rationally and the inability to communicate with people. In addition, unpredictable mood swings, paranoia, behavior changes and violent behavior can occur. (http://www.thecyn.com/club-drug-addiction/long-term-effects- lsd.htm) Signs and symptoms of hallucinogen abuse: Extremely dilated pupils. Warm skin, excessive perspiration, and body odor. Distorted sense of sight, hearing, touch; distorted image of self and time perception. Mood and behavior changes, the extent depending on emotional state of the user and environmental conditions. Unpredictable flashback episodes even long after withdrawal. Walkner, Renee Physiological Comp. May 1, 2011 (http://www.drugd-tech.com/signs_and_symptoms.html#Signs of Hallucinogen Abuse) References 1. http://www.drugfree.org/drug-guide/lsd 2. http://faculty.washington.edu/chudler/lsd.html 3. http://www.nida.nih.gov/infofacts/hallucinogens 4. http://www.justice.gov/dea/concern/lsd.html 5. http://www.medterms.com/script/main/art.asp?articlekey=24170) 6. http://www.pamf.org/teen/risk/drugs/hallucinogens/ 7. http://www.britannica.com/EBchecked/topic/172024/drug-use/40516/Physiological-andpsychological-effects-of-hallucinogens 8. http://www.egetgoing.com/drug_rehab/hallucinogens.asp 9. http://www.thecyn.com/club-drug-addiction/hallucinogen-abuse-fact.html 10. http://www.drugd-tech.com/signs_and_symptoms.html#Signs of Hallucinogen Abuse Walkner, Renee Physiological Comp. May 1, 2011 Walkner, Renee Physiological Comp. May 1, 2011 References 11. http://www.drugfree.org/drug-guide/lsd 12. http://faculty.washington.edu/chudler/lsd.html 13. http://www.nida.nih.gov/infofacts/hallucinogens 14. http://www.justice.gov/dea/concern/lsd.html 15. http://www.medterms.com/script/main/art.asp?articlekey=24170) 16. http://www.pamf.org/teen/risk/drugs/hallucinogens/ 17. http://www.britannica.com/EBchecked/topic/172024/drug-use/40516/Physiological-andpsychological-effects-of-hallucinogens 18. http://www.egetgoing.com/drug_rehab/hallucinogens.asp 19. http://www.thecyn.com/club-drug-addiction/hallucinogen-abuse-fact.html 20. http://www.drugd-tech.com/signs_and_symptoms.html#Signs of Hallucinogen Abuse