Year 13 Biology Unit Plan
Describe applications of biotechnological techniques (Assessed internally AS90718 v2, Biology 3.6, 3 credits)
This achievement standard involves the description of applications of biotechnological techniques to meet human needs and demands.
Achievement Objective: 8.
Part 1: The Gene Seekers
Prior Knowledge
Learning Outcomes
Possible Learning and Assessment
Activities
TIME: 7 Periods
References
Time
Biological Terms: Mutation, gene, family
tree, cancer
Biotechnology applies biological processes to
technological activities or applies modern
technologies to biological processes.
1. Be familiar with the Genome
Analysis Story The Gene Seekers.
2. Identify, define and learn key
terms linked to the human story
in the Gene Seekers
Any technological application that uses
biological systems, living organisms, or
derivatives thereof, to make or modify
products or processes for specific use.
Wikipedia
1
Application Series: the Gene Seekers
Story summary:
http://www.hrc.govt.nz/assets/pdfs
/news/stomach-cancer-mr.pdf
No longer available on line
3. Describe the Application
Genome Analysis
2
1. Read the Genome Analysis Story The
Gene Seekers
2. Handout: Terms Heard of Never heard
of.
3. Research meaning of terms on
handout.
4. Handout 2: Pair Share learning of
terms
5. Define Genome – Meg Bayley p190,
Biozone p53
6. Define genome analysis
7. Describe the purpose of the Human
Genome Project and possible uses for
the information that relate to the
Gene Seekers Story.
8. BioManual
p315-316
–
Genome
Analysis
1.
http://www.answers.com/topic/geno
me good background reading
2. http:/
/www.ornl.gov/sci/techresources/
Human_Genome/home.shtml
More on human genome project
3.http://www.ornl.gov/sci/techres
ources/Human_Genome/posters/be
yondhgp/03-0174.pdf
3,4,5
4. Describe biotechniques used in
genome analysis:
Restriction Enzymes
-
-
-
The term DNA sequencing encompasses
biochemical methods for determining the
order of the nucleotide bases, adenine,
guanine, cytosine, and thymine, in a DNA.
The rapid speed of sequencing attained with
modern DNA sequencing technology has
been instrumental in the large-scale
sequencing of the human genome, in the
Human Genome Project. Wikipedia
6.
7.
-
Ligation
PCR
Gel Electrophoresis
DNA Sequencing
5. Understand why these
biotechniques are useful in
genome analysis
6. Describe the importance of
Genome Analysis for the whanau
and for medical science for the
mutation identified in the Gene
Seekers story
5. Describe the purpose of restriction
enzymes in genome analysis.
6. Explain why restriction enzymes are a
useful technique in Genome Analysis
7. Describe the purpose of ligation in
genome analysis.
8. Explain why ligation is a useful
technique in Genome Analysis
9. Describe the purpose of PCR, the raw
materials and the products.
10. Explain why PCR is a useful technique
in Genome Analysis
11. Describe
the
purpose
of
gel
electrophoresis.
12. Explain why gel electrophoresis is a
useful technique in Genome Analysis
13. Describe the purpose of DNA
sequencing in genome analysis.
14. Explain why a DNA sequence was
needed for identifying the stomach
cancer gene.
15. Student Task Sheet: Case Study the
Gene Seekers
16. Explain how the genome analysis
application
meets
a
human
need/demand in the Gene Seekers
Story.
17. Assessment Task of one application,
http://highered.mcgrawhill.com/olc/dl/120078/bio37.swf
Great animation on how restriction
enzymes (endonucleases) work
Biozone p287 – Restriction Enzymes
Biozone p289 - Ligation
http://www.maxanim.com/genetics
/PCR/PCR.htm
animation on PCR
http://www.youtube.com/watch?v=o
CRJ4r0RDC4
a fun rap on PCR
http://users.ugent.be/~avierstr/prin
ciples/pcrani.html
Biozone p291-294 - PCR
http://course1.winona.edu/sberg/A
NIMTNS/FlashAnimations/SDSgel/sds
GelBasic.swf
BioManual p290 – Gel Electrophoresis
http://www.dnalc.org/ddnalc/resou
rces/cycseq.html
http://www.youtube.com/watch?v=o
YpllbI0qF8&feature=related
http://www.dnalc.org/resources/ani
mations/cycseq.html
two techniques and the human need
/demand