1
Table S1: Categorization of NIAMS 2013 skin-focused grants
Institution
Grant Title
Category
Funding
Albany Medical Keratinocyte Integrin
General cutaneous
$327,125
College
Crosstalk During
research
Wound Healing
Baylor College
Regulation of skin
General cutaneous
$314,982
of Medicine
epithelial stem cell
research
homeostasis
Benaroya
Regulation of TSLPDermatitis
$371,761
Research Inst at
Mediated Skin
including eczema
Virginia Mason
Inflammation
Boston
Higher-order chromatin General cutaneous
$208,718
University
remodeling and
research
Medical Campus regulation of
pigmentation
Molecular control of
General cutaneous
$124,227
normal and neoplastic
research
skin stem cells
Bone Morphogentic
General cutaneous
$335,912
Protein signaling in the
research
control of skin
development, hair grow
Brigham and
The clinical use of Flt3L General cutaneous
$136,350
Women’s
- an immune adjuvant to research
Hospital
potentiate Dendritic
Cells
CD1 presentation of self General cutaneous
$349,999
glycolipids and
research
lipopeptides to T cells
Mac-1 (CR3) and Fc
General cutaneous
$359,430
gamma receptors in
research
immune-mediated
neutrophil cytotoxicity
Immune Evasion in
Non-melanoma
$353,259
Human Squamous Cell
skin cancer
Carcinomas of the Skin Other (Skin
changes due to
chronic exposure to
nonionizing
radiation)
Dermatology Training
Training &
$277,287
Grant
department/institute
program
Skin Homing T Cells
General cutaneous
research
$438,194
Basic Science Grant?
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
Yes
No
No
Yes
2
Brown
University
Case Western
Reserve
University
Children’s
Hospital & Res
Ctr at Oakland
Children’s
Hospital
Corporation
Columbia
University
Ion Channel and
Calcium Signaling in
Ultraviolet Light
Transduction in Human
Skin
IL-17C mediated
mechanisms of
inflammation
Neurogenic
inflammation and
psoriasiform dermatitis
Psoriatic Regulatory T
cell Dysfunction*
PPAR-gamma Signaling
in Normal
Pilosebaceous Units and
in Scarring Alopecia*
NIAMS Core Center:
Skin Diseases Research
Center
Psoriatic Regulatory T
cell Dysfunction*
PPAR-gamma Signaling
in Normal
Pilosebaceous Units and
in Scarring Alopecia*
Training in Investigative
and Molecular
Dermatology
Amelioration of
Vesicant-Induced Skin
Injury by High Dose 25Hydroxyvitamin D
Cancer Associated
Fibroblasts and Basal
Cell Carcinoma
Allografts
Regulators of
Melanocyte and
Melanoma Cell Identity
Hippo signaling and the
control of epidermal
development and
growth
Columbia University
Medical Center Skin
General cutaneous
research
$310,848
Yes
Psoriasis
$363,699
Yes
Psoriasis
$168,406
Yes
Psoriasis
$53,620
Yes
Other (Primary
cicatricial and
scarring alopecia)
$139,500
Yes
Training &
department/institute
program
Psoriasis
$583,725
No
$322,164
Yes
Other (Primary
cicatricial and
scarring alopecia)
$318,942
Yes
Training &
department/institute
program
Miscellaneous
$164,587
No
$788,987
Yes
Non-melanoma
skin cancer
$76,950
Yes
Melanoma
$128,115
Yes
Non-melanoma
skin cancer
$371,925
Yes
Training &
department/institute
$596,614
No
3
Health Sciences
Cornell
University
Duke University
Emory
University
Fred Hutchinson
Can Res Ctr
Disease Research
Center (CUMCSDRC)
Mechanisms of
mechanosensory
transduction in Merkel
cells
Molecular Mechanisms
of Cell Fate Decisions
in Hair Follicle Stem
Cells
JUN PROTEINS IN
EPIDERMAL
HOMEOSTASIS AND
NEOPLASIA
Enhancing the CARRA:
Integration and
Dissemination of
Clinical Data
Cadherin regulation in
dermal endothelial cells
Mechanisms of
epidermal growth
during development,
homeostasis, and
tumorigenesis
A Soft Topical
Antiandrogenic Drug
Glsynthesis, Inc.
Gordon
Research
Conferences
2013 Collagen Gordon
Research Conference
and Gordon Research
Seminar
2013 Epithelial
Differentiation and
Keratinization
GRC/GRS
2013 Tissue Repair and
Regeneration Gordon
Research Conference
2013 Barrier Function
of Mammalian Skin
Gordon Research
program
General cutaneous
research
$327,068
Yes
General cutaneous
research
$347,428
Yes
Non-melanoma
skin cancer
$322,164
Yes
Training &
department/institute
program
$178,708
No
General cutaneous
research
General cutaneous
research
$395,512
Yes
$249,000
Yes
Dermatitis
including eczema
Acne vulgaris
Other (Androgenic
alopecia)
Other
(Hypertrichosis)
Conference
$237,357
Yes
$20,000
No
Conference
$20,000
No
Conference
$22,000
No
Conference
$15,000
No
4
Hampton
University
Harvard
University
(Medical
School)
Henry M.
Jackson FDN for
Adv Mil/Med
Indiana UnivPurdue Univ at
Indianapolis
Jackson
Laboratory
John Wayne
Cancer Institute
Johns Hopkins
University
Kaiser
Foundation
Conferences
Plan and Conduct the
Hampton University
Skin of Color Research
Institute Skin of
Mechanisms of sensory
neuron control over skin
immune responses
Molecular and Cellular
Mechanisms of
Vascular Anomalies
Regulation of Dermal
Fibroblasts in Skin
Regeneration and
Healing
The Indiana Cutaneous
Biological Research
Training Program
Discovering Novel
Gene Networks for Skin
Diseases
Genetics of Alopecia
Areata in the C3H/HeJ
Mouse
Mechanisms of Innate
and Acquired Host
Defense and Tissue
Injury in Skin
Cytokine Regulation of
Wound Induced Skin
Regeneration
Interferons and
cytotoxic lymphocytes
in dermatomyositis and
cutaneous lupus
The structural support
role of keratins in skin
Keratins, Wound
Reepithelialization, and
Hair Follicle Cycling
Transgenic Regulation
of Keratinocyte to
Nociceptor Signaling
Comparative
Effectiveness of Field-
Conference
$15,000
No
Psoriasis
$33,923
Yes
Miscellaneous
$1,457,109 Yes
General cutaneous
research
$320,808
Yes
Training &
department/institute
program
General cutaneous
research
$131,407
No
$191,997
Yes
Alopecia areata
$362,137
Yes
Leprosy
$378,184
Yes
General cutaneous
research
$57,734
Yes
Other (Lupus
erythematosus)
$200,001
Yes
General cutaneous
research
General cutaneous
research
$456,127
Yes
$426,636
Yes
General cutaneous
research
$173,138
Yes
Non-melanoma
skin cancer
$78,966
No
5
Research
Institute
Loyola
University
Chicago
Massachusetts
General Hosp
Mayo Clinic
Arizona
Medical College
of Wisconsin
Treatments for Multiple
Actinic keratoses
Modulating tolerance in
a spontaneous mouse
model of autoimmune
vitiligo
Linking Nicotinic
Activation with Skin
Innate Immunity and
Atopic Dermatitis
Epigenetic regulation of
epidermal homeostasis
7th World Congress on
Itch (WCI)
The MITF
transcriptional network:
melanoma risk and
carcinogenesis
Growth/differentiation
control of keratinocytes
by ROR alpha
Growth differentiation
control in primary
keratinocytes
Inductive properties of
the dermal papilla of the
hair follicle
Itch, proteases and
protease-activated
receptors
The Role of Presenilin
in Hidradenitis
Suppurativa
Eosinophil-nerve
Interactions in Mouse
Models of Dermatitis
Function and Targeting
of CCR6/CCL20 in
Autoimmune
Psoriasiform Skin
Disease
Pediatric Dermatology
Research Alliance
Other (Skin
changes due to
chronic exposure to
nonionizing
radiation)
Other (Vitiligo)
$305,132
Yes
Dermatitis
including eczema
$319,556
Yes
General cutaneous
research
Pruritus
Conference
Melanoma
$337,466
Yes
$15,000
No
$342,200
Yes
General cutaneous
research
$110,376
Yes
General cutaneous
research
$431,247
Yes
General cutaneous
research
$360,840
Yes
Pruritus
$360,436
Yes
Other (Hidradenitis
suppurativa)
$82,650
Yes
Dermatitis
including eczema
$558,283
Yes
Psoriasis
$314,313
Yes
Conference
$59,616
No
6
Montana State
University –
Bozeman
Mount Sinai
School of
Medicine
National Jewish
Health
Nevus Outreach,
Inc.
New York
University
School of
Medicine
Annual Conference
staphylococcus aureus
biofilms mediate
keratinocyte apoptosis
Exploring How Dermal
Papilla Precursors
Regulate Hair Follicle
Formation
A Study of ILV-94
(Anti-22 Antibody)
Administered via IV in
Atopic Dermatitis
Elucidating the
Functions of Epigenetic
Regulators in Control of
Skin Stem Cells
Specification of Dermal
Papilla Cell Fate in the
Hair Follicle Stem Cell
Niche
Role of Chromatin
Regulators in Skin
Control
The Role of Bacterial
Toxins in Human Skin
Disease
2013 International
Expert Meeting on
Congenital Melanocytic
Nevi (CMN) and
Neuroc
Mechanisms of
Homeostasis and
Invasive Cell Migration
in Skin Tumorigenesis*
Biogenesis of
Melanosomes*
The regulation of
melanocyte stem cells
by Wnt signaling
Mechanisms of
Homeostasis and
Invasive Cell Migration
in Skin Tumorigenesis*
Biogenesis of
Bacterial skin
diseases
$68,400
Yes
General cutaneous
research
$359,102
Yes
Dermatitis
including eczema
$631,536
Yes
General cutaneous
research
$236,550
Yes
General cutaneous
research
$345,010
Yes
General cutaneous
research
$362,306
Yes
Dermatitis
including eczema
Bacterial skin
diseases
Conference
Miscellaneous
$292,718
Yes
$30,000
No
Non-melanoma
skin cancer
$101,225
Yes
Melanoma
Other (Vitiligo)
General cutaneous
research
$172,288
Yes
$160,561
Yes
Non-melanoma
skin cancer
$236,549
Yes
Melanoma
$430,695
Yes
7
Melanosomes*
The Pharmacology of
Dermal Fibrosis
Northern
California
Institute/Res/Edu
The regulation of
melanocyte stem cells
by Wnt signaling*
Role of vitamin D
receptor in DNA repair
Vitamin D Receptor
Coactivators in
Keratinocytes
Calcium-sensing
Receptor and
Keratinocyte
Differentiation
MelanocyteKeratinocyte Cross-Talk
In Relation To Barrier
Function
Pathogenesis and
Therapy of Ichthyosis in
Disorders of Lipid
Metabolism
S1P-Mediated
Stimulation of
Antimicrobial Defense
Northwestern
University at
Chicago
The Lipid and Tight
Junction Epidermal
Barriers are
Interdependent
Northwestern
University Skin Disease
Research Core Center
Function of Desmoglein
1/Pemphigus Foliaceus
Antigen
Functional and
Structural Links
between Cadherin,
Gamma-Secretase, and
Notch
Topical Delivery of
siRNA Nanconjugates:
Other (Vitiligo)
Other
(Hypertrophic
disorders of skin)
General cutaneous
research
$336,685
Yes
$361,238
Yes
General cutaneous
research
$188,955
Yes
General cutaneous
research
$304,106
Yes
General cutaneous
research
$304,106
Yes
General cutaneous
research
$304,106
Yes
Other (Other
epidermal
thickening)
$316,778
Yes
Dermatitis
including eczema
Bacterial skin
diseases
Bacterial skin
diseases
$316,778
Yes
$158,389
Yes
Training &
department/institute
program
Other (Other
epidermal
thickening)
General cutaneous
research
$579,500
No
$447,154
Yes
$312,930
Yes
General cutaneous
research
$325,066
Yes
8
Suppressing Epidermal
Hyperplasia
Epha/Ephrin - A
Signaling in Epidermal
Differentiation and
Disease
Desmoplakin Assembly
and Function in
Epidermis
Post Graduate Program
in Cutaneous Biology
The Role of the Skin
Oregon Health & Barrier in Atopic
Science
Dermatitis Development
University
and Prevention*
The Role of the Skin
Barrier in Atopic
Dermatitis Development
and Prevention*
Trim32 Regulation of
Piasy in Skin
Homeostasis
Montagna Symposium
on the Biology of Skin
2013 International
Pachyonychia
Pachyonychia
Congenita
Congenita Consortium
Project
(IPCC) Symposium
Development of Clinical
Trials Outcome
Pennsylvania
Instruments for Acne
State University Vulgaris
Regulation of Cell
Polarity During
Princeton
Epidermal Growth and
University
Homeostasis
UMDNJ/Rutgers
RHBS-Robert
University CounterACT
Wood Johnson
Research Center of
Medical School
Excellence
Regulation of
Quiescence and
Rockefeller
Activation in Skin Stem
University
Cells
Mechanisms used by
General cutaneous
research
$324,896
Yes
General cutaneous
research
$441,823
Yes
Training &
department/institute
program
Dermatitis
including eczema
$109,847
No
$994
No
Dermatitis
including eczema
$127,980
No
Psoriasis
$312,848
Yes
Conference
$38,000
No
Conference
Miscellaneous
$12,500
No
Acne vulgaris
$204,113
No
General cutaneous
research
$236,550
Yes
Training &
department/institute
program
Miscellaneous
General cutaneous
research
$2,369,028 No
$96,471
Yes
General cutaneous
$95,593
Yes
9
Scarless
Laboratories,
Inc.
skin dendritic cells to
induce regulatory T
cells
Role of Primary Cilia
During Epidermal
Morphogenesis
Regulation of Epidermal
Development and
Differentiation
Skin Stem Cells:
Purification and
Characterization
Origin and Function of
Inflammatory Dendritic
Cells in Psoriasis.
Cell adhesion and
cytoskeletal dynamics in
skin
A novel anti-scar
peptide for cutaneous
wound repair
ATP in Skin Immunity
Scripps Research
Institute
Signum
A Topical Non-steroidal
Biosciences
Anti-inflammatory for
Atopic Dermatitis
Sloan-Kettering
The role of melanocyte
Inst Can Res
precursors in zebrafish
pigmentation disorders
THE FRAMINGHAM
SCHOOL STUDY OF
NEVI IN CHILDREN
SONIC II
Society for
SID Retreat for Future
Investigative
Academicians
Dermatology
Stanford
Characterization of
University
Homeostatic Regulators
Disrupted in Epidermal
Neoplasia
Homeostatic Regulators
Disrupted in Skin
Carcinogenesis
research
General cutaneous
research
$95,796
Yes
General cutaneous
research
$573,687
Yes
General cutaneous
research
$343,320
Yes
Psoriasis
$362,306
Yes
General cutaneous
research
$730,724
Yes
Other
(Hypertrophic
disorders of skin)
Other (Skin
changes due to
chronic exposure to
nonionizing
radiation)
Dermatitis
including eczema
$199,740
Yes
$122,850
Yes
$998,971
No
Melanoma
$126,900
Yes
Miscellaneous
$669,406
No
Conference
$25,000
No
Non-melanoma
skin cancer
$125,604
Yes
Non-melanoma
skin cancer
$330,543
Yes
10
Regulating Gli Function
in Hair Follicle
Progenitors
Regulation of human
skin homeostasis by
histone arginine
methylation regulators
Gene Regulatory
Mechanisms of
Epidermal Growth
Stromal Regulation of
Basal Cell Carcinoma
Formation
Laminins in the Skin
State University
New York Stony
Brook
State University
of New York at
Buffalo
Sunny
Biodiscovery,
Inc.
SUNY
Downstate
Medical Center
Surface
Bioadvances,
Inc.
Thomas
Jefferson
Signaling Regulators of
Epithelial Homeostasis
and Neoplasia
Gene Transfer for
Recessive Dystrophic
Epidermolysis Bullosa
Postgraduate Training
Program in Epithelial
Biology
Cx26 mutations in
syndromic deafness
linked to skin disease
Planar Cell Polarity
Signaling in Hair
Follicle Formation
Novel Genetic Models
to Study the Role of
DNp63 in Squamous
Cell Carcinoma
Novel Skin Protectant
Retinoid for the
Treatment of Psoriasis
Mouse nude locus and
skin development
Bacterial fermentation
in skin microbiome as
probiotics (Bfismp)
against S. aureu
Mechanism of skinspecific targeting of
Non-melanoma
skin cancer
$340,401
Yes
General cutaneous
research
$55,670
Yes
General cutaneous
research
$403,274
Yes
Non-melanoma
skin cancer
$344,324
Yes
General cutaneous
research
Non-melanoma
skin cancer
$326,571
Yes
$324,157
Yes
Other (Pemphigoid) $615,434
Yes
Training &
department/institute
program
General cutaneous
research
$157,528
No
$320,405
Yes
General cutaneous
research
$334,368
Yes
Non-melanoma
skin cancer
$79,500
Yes
Psoriasis
$149,451
Yes
General cutaneous
research
$324,021
Yes
Bacterial skin
diseases
$150,000
Yes
Other (Pemphigoid) $329,375
Yes
11
University
Transderm, Inc.
Univ of
Massachusetts
Med Sch
Worchester
Univ of North
Carolina Chapel
Hill
University of
Alabama at
adult stem cells
Role of Desmosomal
Adhesion in
Carcinogenesis
Mineralization/AntiMineralization
Networks in the Skin
TRAINING IN
MOLECULAR
DERMATOLOGY
AND CUTANEOUS
CONNECTIVE
TISSUE DISEASES
Pachyonychia congenita
clinical trial using
therapeutic self-delivery
siRNAs
Use of comparative
genomics to identify
novel regulators of
melanoma progression
Targeting IFN gamma
and chemokines to treat
vitiligo in a humanized
mouse model
Etiology and
Pathogenesis of
Pemphigus
Interactions of lgC4 &
lgE anti-Dsg1
Autoantibodies in
Endemic Pemphigus
Foliaceu*
Interactions of lgC4 &
lgE anti-Dsg1
Autoantibodies in
Endemic Pemphigus
Foliaceu*
Role of the matrix
metalloproteinase in
pemphigus
autoantibody-mediated
epidermal
UAB Skin Diseases
Research Center
Non-melanoma
skin cancer
$317,034
Yes
Other (Other
localized
connective tissue
disorders)
Training &
department/institute
program
$150,587
Yes
$76,161
No
Miscellaneous
$1,045,754 Yes
Melanoma
$353,813
Yes
Other (Vitiligo)
$123,660
Yes
Other (Pemphigus)
$323,000
Yes
Other (Pemphigus)
$39,793
Yes
Other (Pemphigus)
$109,322
Yes
Other (Pemphigus)
$284,715
Yes
Training &
department/institute
$485,498
No
12
Birmingham
University of
Arizona
University of
California
University of
California
Berkeley
University of
California Davis
University of
California Irvine
Therapeutic
Intervention of
Lewisite-Mediated
Cutaneous BlisteringInflammation
GILT and regulation of
Treg development in
cutaneous autoimmunity
Epigenetic Regulators in
Epidermal Homeostasis
and Neoplasia
Genetic Influence in
Pediatric Psoriasis
Proteolysis and Skin
Antimicrobials
UCSD Dermatologist
Investigator Training
Program
Roles and functions of
ion channels that
mediate mammalian
touch transduction.
Warmth enhancement of
itch via TRPV4
Galectin-3 in regulation
of allergic skin
inflammation
Neural mechanisms of
itch
Molecular mechanisms
of pulsed dye laser
combined with topical
rapamycin for port
Phosphoinositide
Signaling Regulates
Melanogenesis*
Transcriptional CoRegulatiors in
Epidermis
Circadian Clock
Regulation in Skin
Phosphoinositide
Signaling Regulates
Melanogenesis*
Aldehyde
program
Miscellaneous
$366,251
Yes
Other (Vitiligo)
$75,750
Yes
Non-melanoma
skin cancer
$125,361
Yes
Psoriasis
$132,300
Yes
Bacterial skin
diseases
Training &
department/institute
program
General cutaneous
research
$331,313
Yes
$197,548
No
$320,817
Yes
Pruritus
$87,885
Yes
Dermatitis
including eczema
$314,384
Yes
Pruritus
$312,848
Yes
Miscellaneous
$88,700
No
Non-melanoma
skin cancer
$331,957
Yes
General cutaneous
research
$319,730
Yes
Non-melanoma
skin cancer
Non-melanoma
skin cancer
$326,162
Yes
$48,532
Yes
General cutaneous
$123,919
Yes
13
University of
California Los
Angeles
University of
California San
Francisco
dehydrogenase: A novel
regulator of melanin
biogenesis
Characterization of the
Lysogenic Pathway in
P. acnes Bacteriophages
Regulation of
Langerhans Cell
Migration by Invariant
Gamma Delta T Cells
Immunobiology of
Leprosy
CD1-restricted T Cell
Responses in Skin
Innate Immunity in
Acne Vulgaris
Dermatology Scientist
Training Program
Identification of Causal
Variants in Psoriasis
Generation and
maintenance of effector
and regulatory T cells in
the skin
Genetic Analysis of the
TNF Pathway in
Psoriasis*
Genetic Analysis of the
TNF Pathway in
Psoriasis*
Mechanisms of immune
regulation in the skin
Patient-Oriented
Research in Skin
Diseases
Hedgehog signaling at
the cell's antenna:
Smoothened and the
primary cilium
Cytokine Signaling in
Neurons: Inflammation,
Pain and Pruritis
UCSF Dermatology
Training Grant
research
Acne vulgaris
$20,553
Yes
Other (Lupus
erythematosus)
$124,470
Yes
Leprosy
$1,409,483 Yes
Leprosy
$503,165
Yes
Acne vulgaris
$244,717
Yes
Training &
department/institute
program
Psoriasis
$172,328
No
$465,839
Yes
General cutaneous
research
$78,500
Yes
Psoriasis
$1,000
Yes
Psoriasis
$119,610
Yes
General cutaneous
research
Non-melanoma
skin cancer
$125,685
Yes
$182,524
No
General cutaneous
research
$293,915
Yes
Pruritus
$330,244
Yes
Training &
department/institute
$202,247
No
14
program
University of
Coordinated
General cutaneous
Chicago
cytoskeletal dynamics in research
skin somatic stem cells Resubmission 01
Epidemic CA-MRSA:
Bacterial skin
Molecular
diseases
Epidemiology and
Immunology
University of
Coordinated Regulation General cutaneous
Cincinnati
of Hair Growth and
research
Pigmentation by Dermal
Papilla Cells
University of
MicroRNA-mediated
General cutaneous
Colorado
Regulation in
research
Mammalian Skin
University of
Genetic studies of
Other (Vitiligo)
Colorado Denver vitiligo
Targeting p53Other (Vitiligo)
Dependent
Repigmentation in
Vitiligo
Molecular Analysis,
Training &
Modeling and
department/institute
Correction of Skin
program
Diseases
Vitiligo
Other (Vitiligo)
Testing the Therapeutic Other (Pemphigoid)
Potential of iPS Cells
for Inherited Skin
Diseases
The consequences of
Dermatitis
loricrin deficiency on
including eczema
epidermal barrier
Other (Pemphigoid)
function
The role of p63 in hair
Non-melanoma
follicle stem cells and
skin cancer
cancer
University of
Regulation of the
General cutaneous
Iowa
melanocyte lineage by
research
the AP2 transcription
factor family
Controlling the
Other
Mechanobiology of
(Hypertrophic
Cutaneous Wounds to
disorders of skin)
Reduce Hypertrophic
$348,394
Yes
$320,112
Yes
$74,575
Yes
$306,508
Yes
$446,579
Yes
$100,572
Yes
$596,840
No
$386,021
$327,661
Yes
Yes
$313,443
No
$318,881
Yes
$319,972
Yes
$75,500
Yes
15
University of
Kentucky
University of
Maryland
Baltimore
University of
Michigan
University of
Minnesota
Scar
Non-contact Diffuse
Optical Assessment of
Pressure Ulcer and
Therapy
Keratoderma- an
Exploratory Study
Biologic Activities of
IL-36 Cytokines in
Psoriasis
The Role of Innate
Immunity in Systemic
and Cutaneous Lupus
Functional Genomics of
Psoriasis
Mechanisms of Altered
Skin ReEpithelialization in
Aging
Role of the Psoriasis
Associated IL23R Risk
Variants on Th17
Biology and Function
Characterizing the Cells
of Origin for Basal Cell
Carcinoma
Linkage Analysis of
Familial Psoriasis
Molecular Regulation of
Hair Follicle
Morphogenesis
Role of Mast Cells in
NLRP3-Mediated Skin
Inflammation
TRP Ca2+ Channels in
the Skin
Skin-targeted Cell
Therapy for Recessive
Dystrophic
Epidermolysis Bullosa
Role of Langerhans
Cells in the Cutaneous
Immune System
Decubitus ulcer
$156,387
No
Other (Other
epidermal
thickening)
Psoriasis
$163,094
Yes
$101,142
Yes
Other (Lupus
erythematosus)
$128,232
Yes
Psoriasis
$470,734
Yes
General cutaneous
research
$96,760
Yes
Psoriasis
$126,900
Yes
Non-melanoma
skin cancer
$233,460
Yes
Psoriasis
$592,896
Yes
General cutaneous
research
$319,086
Yes
General cutaneous
research
$319,086
Yes
Non-melanoma
$322,870
skin cancer
Other (Pemphigoid) $458,962
Yes
General cutaneous
research
Yes
$299,937
Yes
16
University of
Pennsylvania
Regulated Activation of
Latent-TGFb
Determines Langerhans
Cell Migration
Identification of a
Keratinocyte Stem Cell
Regulatory Gene in the
KSC2 Locus
Psoriasis and the risk of
diabetes
HDAC functions in skin
development, renewal
and disease
Hair follicle neogenesis
in response to wounding
Migration of Skin
Antibody Secreting
Cells
Core Center
Cloning and genetics of
human pemphigus
autoantibodies
Characterization of
neural crest stem cells in
human hair follicles.
Regulation of T cell
egress from inflamed
skin
Filaggrin Mutations and
the Prognosis of Atopic
Dermatitis
Role of autoantibody
isotype in pemphigus
pathogenesis
WNT signals in skin
and hair development
and hair growth
Dermatology Research
Training Grant
University of
Pittsburgh at
Pittsburgh
Investigating the Neural
Circuits of Itch
Using dual
General cutaneous
research
$322,763
Yes
General cutaneous
research
$326,539
Yes
Psoriasis
$162,474
No
Non-melanoma
skin cancer
$340,000
Yes
General cutaneous
research
General cutaneous
research
$340,000
Yes
$53,942
Yes
Training &
department/institute
program
Other (Pemphigus)
$608,000
$342,000
Yes
General cutaneous
research
$319,958
Yes
General cutaneous
research
$325,037
Yes
Dermatitis
including eczema
$297,498
No
Other (Pemphigus)
$334,703
Yes
General cutaneous
research
$342,000
Yes
Training &
department/institute
program
Pruritus
$280,794
No
$324,063
Yes
Pruritus
$194,438
Yes
17
intersectional genetics
to understand and
modulate itch
T-helper cell cytokine
profile in localized
scleroderma*
T-helper cell cytokine
profile in localized
scleroderma*
University of
Rochester
University of
Southern
California
University of
Tennessee
Health Sci Ctr
University of
The role of Atoh1 in the
development and
function of Merkel cells
NF kappa B Activity in
Skin Inflammation and
Carcinogenesis
Training Grant in
Dermatology
Development and
Regeneration of Skin
Appendages
Pattern Formation
During Skin
Organogenesis
Development of
Extracellular Heat
Shock Protein-90 as a
Novel Topical Wound
Heali
Tissue Engineering of
New Hair Formation
Activator Inhibitor
interactions in the cyclic
regeneration of hair
follicle stem
Isolation and
characterization of new
adult stem cells from
sweat glands
Role of exogenous
melatonin in skin
biology
Regulation of
Other (Other
localized
connective tissue
disorders)
Other (Other
localized
connective tissue
disorders)
General cutaneous
research
$693
Yes
$125,679
Yes
$308,836
Yes
General cutaneous
research
$120,922
Yes
Training &
department/institute
program
General cutaneous
research
$212,813
No
$439,908
Yes
General cutaneous
research
$350,639
Yes
General cutaneous
research
$346,275
Yes
General cutaneous
research
$332,424
Yes
General cutaneous
research
$350,550
Yes
General cutaneous
research
$76,950
Yes
General cutaneous
research
$316,350
Yes
General cutaneous
$307,390
Yes
18
Toledo Health
Sci Campus
University of
Virginia
University of
Washington
University of
WisconsinMadison
UT MD
Anderson
Cancer Ctr
Melanocyte
Differentiation by
SWI/SNF Chromatin
Remodeling Enzymes
Regulation of TSLP
receptor expression and
function in eczema in
mice and man
The replication
checkpoint and genomic
fidelity in skin
Keratin Gene Targeting
for the Treatment of
Epidermolysis Bullosa
Training for
Investigative
Dermatology
RNA-binding protein
CRD-BP in melanocyte
biology
18th Annual Meeting of
the PanAmerican
Society of Pigment Cell
Research
Role of Polo-Like
Kinase-1 in Melanocytic
Transformation
Caspase-14 and the
Treatment of Psoriasis
Autophagy in epidermal
melanocyte: a protective
or a destructive role?
The Cutaneous Biology
of MAGE Transcription
Factors
Identification of
Dysregulated Stress
Response Mechanisms
in Chronic Urticaria
Investigative
Dermatology Training
Program at University
of Wisconsin-Madison
Keratinocyte Activation
by Slug-induced
Calprotectin
research
Dermatitis
including eczema
$515,908
Yes
Non-melanoma
skin cancer
$334,455
Yes
Other (Pemphigoid) $302,236
Yes
Training &
department/institute
program
General cutaneous
research
$148,770
No
$316,379
Yes
Conference
$24,000
No
Melanoma
$303,130
Yes
Psoriasis
$304,722
Yes
General cutaneous
research
$164,913
Yes
Melanoma
$160,847
No
Urticaria
$193,016
No
Training &
department/institute
program
$220,580
No
General cutaneous
research
$202,635
Yes
19
UT
Southwestern
Medical Center
Vanderbilt
University Med
Ctr
Wake Forest
University
Health Sciences
Washington
University
Yale University
Molecular Markers in
Discoid Lupus
Erythematous
Striatal Dopamine
Release in Response to
Ultraviolet Light in
Compulsive Tanners
Other (Lupus
erythematosus)
$123,012
Yes
Other (Skin
changes due to
chronic exposure to
nonionizing
radiation)
$169,931
No
Linking Lipoxygenases
with Essential Fatty
Acids and Epidermal
Barrier Formation
Skin Regeneration with
Stem Cells and
Scaffolds
The role of microRNA
miR-31 in skin biology
Regulation of Itch
Scratching by Spinal
GRP Receptors in
Primates
Behavioral
Pharmacology of Itch
Smart Laser Treatment
of Port-Wine Stain in
Children
Molecular Mechanisms
of the Itch Sensation in
the Spinal Cord
Skin Development
Analysis in Mutant
Mouse Lines
Extrinsic Regulation of
Epidermal
Homeostatasis
Mechanisms of Genetic
Reversion in Ichthyosis
With Confetti
Live Imaging of Skin
Regeneration
Dermatology Training
Grant
Other (Other
epidermal
thickening)
$333,450
Yes
General cutaneous
research
$601,177
Yes
General cutaneous
research
Pruritus
$333,450
Yes
$195,075
Yes
Pruritus
$314,469
Yes
Miscellaneous
$86,865
No
Pruritus
$308,785
Yes
General cutaneous
research
$355,716
Yes
General cutaneous
research
$355,716
Yes
$355,894
Yes
$355,894
Yes
$226,521
No
Other (Other
epidermal
thickening)
General cutaneous
research
Training &
department/institute
program
* Distinct grants despite having same title
20
Table S2. 15 Skin conditions studied by GBD 2010 and grant title or abstract terms
supporting inclusion
Skin Condition (ICD-10
Grant Title or Abstract Terms
a
codes)
Dermatitis including eczema “eczema” “dermatitis” “atopic dermatitis” “contact
(L20-L27)b
dermatitis” “irritant contact dermatitis”
“allergic contact dermatitis” “exfoliative dermatitis”
“diaper dermatitis” “seborrheic dermatitis”
Acne vulgaris (L70)
“acne vulgaris” “acne”
Bacterial skin diseases
“staphylococcal scalded skin syndrome” “impetigo”
(L00,L01, L02, L04, L08,
“cutaneous abscess/furuncle/ carbuncle” “lymphadenitis”
L88,L97, L98.0-L98.4)
“pyoderma” “erythrasma” “bacteria skin”
Viral skin diseases (B00,
“herpes” “viral warts” “molluscum contagiosum”
B07-B09)
“exanthema subitum” “viral” and “skin”
Urticaria (L50)
“urticaria”
Fungal skin diseases (B35,
“fungal” and “skin” “candidiasis” “tinea”
B36.0, B36.1, B36.2, B36.3,
B36.8, B36.9)
Pruritus (L29)
“pruritus” “itch”
Scabies (B66)
“scabies”
Alopecia areata (L63.0,
“alopecia areata”
L63.1, L63.8, L63.9)
Cellulitis (L03.0, L03.1,
“cellulitis”
L03.2-L03.9)
Decubitus ulcer (L89)
“decubitus ulcer” “pressure wound”
Melanoma (C43)
“melanoma”
Psoriasis (L40, L41)
“psoriasis”
Non-melanoma skin cancer
“non-melanoma skin cancer” “basal cell carcinoma”
(C44, D04)
“squamous cell carcinoma”
Leprosy (A30)
“leprosy”
a
See reference 11
*excluded L28 (lichen simplex chronicus and prurigo)
21
Table S3. “Other skin and subcutaneous diseases” studied by GBD 2010 and grant
title or abstract terms supporting inclusion
GBD “other skin and
Abstract/project terms supporting inclusion
subcutaneous diseases”
category (ICD-10 code)a
Pediculosis and phthiriasis
“pediculosis” “phthiriasis”
(B85)
Myiasis (B87)
“myiasis”
Other infestations (B88)
“ acariasis” “tungiasis” or “sandflea” “scarabiasis” or
“arthropod” “hirudiniasis” or “leech”
“ichthyoparasitism” “vandellia cirrhosa” “linguatulosis”
“porocephaliasis” “skin infestation” “mites” “skin
parasites”
Pilonidal cyst with and
“pilonidal cyst”
without abscess (L05.0 and
L05.9)
Pemphigus (L10)
“pemphigus”
Other acantholytic disorders
“keratosis follicularis” “acantholytic dermatosis”
(L11)
“acantholytic”
Pemphigoid (L12)
“pemphigoid” “bullous” or “bulla” “epidermolysis
bullosa”
Other bullous disorders (L13) “dermatitis herpetiformis” “subcorneal pustular
dermatitis” “bullous” “bulla”
Lichen simplex chronicus and “lichen simplex chronicus” “prurigo”
prurigo (L28)
Other dermatitis (L30)
“nummular dermatitis” “dyshidrosis” “cutaneous
autosensitization” “infective dermatitis” “erythema
intertrigo” “pityriasis alba”
Pityriasis rosea (L42)
“pityriasis rosea”
Lichen planus (l42)
“lichen planus”
Other papulosquamous
“pityriasis rubra pilaris” “lichen nitidus” “lichen
disorders (L44)
striatus” “lichen ruber moniliformis” “infantile papular
acrodermatitis” or “Giannotti-Crosti”
“papulosquamous”
Erythema multiforme (L51)
“erythema multiforme” “Stevens Johnson”
Erythema nodosum (L52)
“erythema nodosum”
Other erythematous conditions “toxic erythema” “erythema annulare centrifugum”
(L53)
“erythema marginatum” “chronic figurate erythema”
Sunburn (L55)
“sunburn”
Other acute skin changes due
“drug phototoxic” “drug photoallergic” “photocontact
to ultraviolet radiation (L56)
dermatitis” “solar urticaria” “polymorphous light
eruption” “acute” and “UV” or “ultraviolet”
Skin changes due to chronic
“actinic keratosis” “actinic reticuloid” “cutis
exposure to nonionizing
rhomboidalis nuchae” “poikiloderma of Civatte” “cutis
radiation (L57)
laxa senilis” “actinic granuloma” “nonionizing
22
Radiodermatitis (L58)
Other disorders of skin and
subcutaneous tissue related to
radiation (L59)
Nail disorder (L60)
radiation” “wrinkles” “chronic” and “UV” or
“ultraviolet” “tanning”
“radiodermatitis”
“erythema ab igne” “dermatitis ab igne”
“nail” “ingrowing” “onycholysis” “onychogryphosis”
“Beau lines” “yellow nail syndrome”
Androgenic alopecia (L64)
Other nonscarring hair loss
(L65)
“androgenic alopecia”
“telogen effluvium” “anagen effluvium” “alopecia
mucinosa” “nonscarring” “hair loss” “alopecia”
Cicatricial alopecia (scarring
hair loss) (L66)
“pseudopelade” “lichen planopilaris” “folliculitis
decalvans” “perifolliculitis capitis abscedens”
“folliculitis ulerythematosa reticulate” “cicatricial”
“scarring” “hair loss” “alopecia”
“trichorrhexis nodosa” “hair color” “hair shaft”
Hair color and hair shaft
abnormalities (L67)
Hypertrichosis (L68)
Rosacea (L71)
Follicular cysts of skin and
subcutaneous tissue (L72)
Other follicular disorders
(L73)
Eccrine sweat disorders (L74)
apocrine sweat disorder (L75)
Vitiligo (L80)
Other disorders of
pigmentation (L81)
Seborrhoeic keratosis (L82)
Acanthosis nigricans (L83)
Corns and callosities (L84)
Other epidermal thickening
(L85)
Transepidermal elimination
disorders (L87)
Atrophic disorders of skin
(L90)
“hirsutism” “hypertrichosis” “polytrichia”
“rosacea” “perioral dermatitis” “rhinophyma”
“cyst” “follicular” “epidermal” “trichilemmal”
“steatocystoma”
“acne keloid” “pseudofolliculitis barbae” “hidradenitis
suppurativa”
“eccrine sweat” “miliaria” “anhydrosis”
“apocrine sweat” “bromhidrosis” “chromhidrosis”
“apocrine miliaria”
“vitiligo”
“hyperpigmentation” “chloasma” “freckles” “café au
lait spots” “leukoderma” “hypopigmentation”
[excluding “vitiligo] “pigmented purpuric dermatosis”
“iron pigmentation” “tattoo pigmentation”
“seborrhoeic keratosis”
“acanthosis nigricans”
“corn” “callous”
“(acquired) icthyosis” “keratoderma”
“(acquired)keratosis” “xerosis cutis” “epidermal
thickening”
“keratosis follicularis et parafollicularis in cutem
penetrans” “reactive perforating collagenosis” “elastosis
perforans serpiginosa” “transepidermal”
“lichen sclerosis” “anetoderma” “atrophoderma”
“acrodermatitis chronica atrophicans” “adherent scar”
“cicatrix” “striae atrophicae”
23
Hypertrophic disorders of skin
(L91)
Granulomatous disorders of
skin and subcutaneous tissue
(L92)
Lupus erythematosus (L93)
Other localized connective
tissue disorders (L94)
“hypertrophic scar” “keloid”
“granuloma annulare” “necrobiosis lipoidica”
“granuloma faciale” “eosinophilic granuloma of skin”
“foreign body granuloma” and “skin”
“discoid” “cutaneous” and “lupus” “local” and “lupus”
“localized scleroderma” “morphea” “linear
scleroderma” “calcinosis cutis” “sclerodactyly”
“Gottron papules” “poikiloderma vasculare
atrophicans” “ainhum”
L95: Vasculitis limited to skin, “livedoid vascultitis” “erythema elevatum diutinum”
not elsewhere classified (L95) “vasculitits” and “skin”
a
See reference 11
24
Table S4. Additional categories and grant title or abstract terms supporting
inclusion
Category
Abstract/project terms supporting inclusion
Training &
department/institution
program
Conference
Other miscellaneous skin
diseases (not in other GBD
category)
“dermatology” and “training” (excludes conferencespecific training; excludes training of one individual
outside of a designated program)
“skin/dermatology” and “conference/symposium” “retreat”
dates and place of event given
“pachyonychia congenita” “port wine stain”
“hemangioma” “melanocytic nevi” vesicant induced skin
injury including but not limited to: “lewsite-mediated
cutaneous blistering-inflammation ” “nitrogen mustardrelated nitrosureas” induced skin injury