Running head: STROKE: A PUBLIC HEALTH PERSPECTIVE Stroke: A Public Health Perspective Katelyn R. Strasser Concordia University Nebraska 1 STROKE: A PUBLIC HEALTH PERSPECTIVE 2 Cardiovascular disease is often first associated with diseases pertaining to the heart, which are the leading cause of death in the United States. However, cardiovascular disease also refers to stroke, a disease that requires emergent attention and is the fourth leading cause of death in the United States (American Stroke Association, 2013). This paper will discuss the epidemiology and biostatistics of stroke, the medical basis for stroke, the social and behavioral factors that affect this disease, and ways that the government is trying to combat stroke through public health initiatives. Biostatistical data illustrates the implications of stroke. As many as 795,000 Americans suffer from a new or recurrent stroke each year, resulting in one stroke every forty seconds (American Stroke Association, 2013). Vital statistics from 2009 indicate that just less than 130,000 people in the United States died of stroke. Cerebrovascular accidents accounted for 5.3% of all deaths (Kochanek, Xu, Murphy, Miniño, & Kung, 2011). About 6.8 million Americans older than 20 years of age have had a stroke, making the prevalence from 2007-2010 an estimated 2.8%. It is predicted that by 2030, 4 million more people will have had a stroke, increasing the prevalence by 21.9% from 2013 (American Heart Association, 2013). A stroke occurs when there is a lack of blood flow to the brain or a hemorrhage into the brain, causing death of the cells. Strokes may be ischemic or hemorrhagic in nature. Ischemic strokes occur from a clot in the vessels of the brain and are either thrombotic or embolic. Thrombotic strokes occur after there has been an injury to the blood vessel wall (Lewis et. al., 2007). As the vessel attempts to repair itself, fragments of cholesterol and fat deposit on the cell wall and begin to form a clot (Schneider, 2011). STROKE: A PUBLIC HEALTH PERSPECTIVE 3 The condition of fatty deposits building up in the vessels is called atherosclerosis. When atherosclerosis occurs to the degree where a vessel becomes occluded, blood cannot reach the brain and a stroke occurs. Embolic strokes are also due to clots, but these clots originate from somewhere else in the body such as the heart, and become lodged in a vessel as they travel through the circulation (Lewis et. al., 2007). Eighty percent of strokes are ischemic. The other twenty percent of strokes are hemorrhagic. Hemorrhagic strokes are a result of bleeding into the brain. Hypertension is the most common cause of hemorrhagic strokes (Moulton, 2009). Other sources include coagulation disorders, anticoagulant and thrombolytic drugs, trauma, brain tumors, and ruptured aneurysms (Lewis et. al., 2007). According to Lewis (2007) a transient ischemic attack, sometimes called a “mini stroke,” is a “temporary loss of neurologic function caused by ischemia” of part of the brain. The symptoms of most TIAs resolve within three hours, but it is still important to take TIAs seriously, because they are warning signs of progressive cerebrovascular disease (Lewis et. al., 2007). Stroke is the leading cause of disability in the United States (American Stroke Association, 2013). Strokes can have detrimental effects on the body, depending on where in the brain the stroke occurred. Side effects of stroke include paralysis of one or more limbs, loss of sensation in extremities, facial droop, hearing loss, personality changes, cognitive impairment, visual disturbances, gait impairment, and many other devastating results. If the stroke occurs on the left side of the brain, the right side of the body is affected and vice-versa (Lewis et. al., 2007). The treatment and rehabilitation needed to care for these side effects is very expensive. In 2010, stroke-related medical STROKE: A PUBLIC HEALTH PERSPECTIVE 4 costs and disability totaled about 73.7 billion dollars (American Stroke Association, 2013). Stroke is caused by both non-modifiable and modifiable risk factors. The nonmodifiable risk factors include advanced age, sex, race, and genetic susceptibility. Risk factors that are modifiable include diet, exercise, use of tobacco and alcohol (Sherzai, Heim, Boothby, & Sherzai, 2012). Other factors that can be changed include having high blood pressure, high cholesterol, atrial fibrillation or other heart disease, carotid artery disease, or diabetes mellitus (American Stroke Association, 2013). Biostatistics and epidemiological data describe the relationship between age, gender, race, and the incidence of stroke. According to the American Heart Association’s latest report in Circulation, women have a higher lifetime risk of stroke. In the age group of 55 to 75 years, 1 in 5 women suffer from a stroke, while only 1 in 6 men in the same age group have a stroke. Some data shows that women may have a lower incidence early on in life, but after menopause the incidence increases to greater than that of men (American Heart Association, 2013). Race and geographic location are also indicative of stroke risk. Data from the CDC in 2010 reports that 2.4% of non-Hispanic whites over 18 years of age have had a stroke, compared to 3.9% of non-Hispanic blacks, 1.5% of Asian/Pacific Islanders, 2.5% of Hispanics, and 5.9% of American Indian or Alaska Natives. From 2006-2010, the Centers for Disease Control (CDC) analyzed trends in stroke prevalence with data from the Behavioral Risk Factor Surveillance System. The results of this study were categorized by sociodemographic characteristics and state of residence. This study concluded that persons living in the Southeastern United States had the highest stroke STROKE: A PUBLIC HEALTH PERSPECTIVE 5 prevalence. The age-adjusted stroke prevalence in 2010 was greatest in Alabama (4.1%), while it was lowest in Connecticut (1.5%) (Centers for Disease Control and Prevention, 2012). Alabama is one state included in the “stroke belt” of the United States, where people are at an increased risk for stroke. The stroke belt is a geographic region made up of eight states including North Carolina, South Carolina, Georgia, Tennessee, Mississippi, Alabama, Louisiana, and Arkansas. The stroke mortality here is 20% higher than in the rest of the United States. The “stroke buckle” is a small region in the coastal plain of North Carolina, South Carolina, and Georgia where the stroke mortality is even greater, averaging 40% higher than the rest of the country (American Heart Association, 2013). Combating high blood pressure, or hypertension, is one of the most important steps in reducing the risk of stroke in the stroke belt and across the entire nation. The advised healthy blood pressure is 120/80, and anything over 140/90 is considered hypertension. Hypertension is affected by the amount of fat in a person’s blood, or cholesterol level. Cholesterol is a part of a typical American’s diet that has also been shown to increase the risk for stroke. Maintaining a total cholesterol level less than 200 is recommended. Foods like eggs, meat, and milk are common sources of cholesterol, while fish, olive oil, and oat bran have positive effects on blood lipids. Regular exercise lowers total cholesterol, while smoking lowers HDL (good cholesterol) levels. The nicotine in tobaccos has also been found to raise blood pressure and place stress on the heart and blood vessels. Over an extended period of time, this stress and damage can lead to atherosclerosis. Increasing physical activity can combat hypertension and stroke STROKE: A PUBLIC HEALTH PERSPECTIVE 6 as well. If blood pressure cannot be reduced by these modifications, a medication to lower blood pressure may be prescribed (Schneider, 2011). While hypertension is seen across all races, this disease disproportionately afflicts African Americans. In fact, the prevalence of hypertension in African Americans is about 34% in males and 31% in females, while the prevalence is 25.4% in white, nonHispanic males and 21% in white females. Research shows that these discrepancies are related to a variety of causes. African Americans’ socioeconomic status is generally poorer, resulting in less treatment for hypertension. This group is more likely to wait for treatment until they notice signs of organ damage. They are less likely to be able to afford treatment and may not receive the necessary education needed to battle hypertension (Moulton, 2009). Hypertension, high cholesterol, smoking, obesity, and inactivity are all factors that have been linked to cardiovascular disease and stroke. However, other influences, both individually and linked to the aforementioned factors, can play a role in stroke incidence. These social influences include marriage status, socioeconomic status, and place of residence. Other behavioral influences can affect the length of time that it takes people to seek medical attention after they have experienced stroke symptoms. The ecological model of health behavior and the health belief model can help examine these relationships. According to the ecological model of health behavior, five different levels of influence exist that determine peoples’ health behaviors. These five levels are intrapersonal factors, interpersonal factors, institutional factors, community factors, and public policy. Many of the risk factors for stroke are intrapersonal. Individuals have STROKE: A PUBLIC HEALTH PERSPECTIVE 7 personal attitudes, beliefs, and practices, which may contribute to their food choices, level of physical activity, or choice to smoke. These three are in turn linked to hypertension and high cholesterol (Schneider, 2011). Recent research is interested in how other social factors may be affecting people at the community level. One particular concern is the effect that the socioeconomic status of a neighborhood could have on the incidence of stroke (Augustin, Glass, James, & Schwartz, 2008). A study conducted in Baltimore, Maryland studied the connection between place of residence and cardiovascular disease. Self-reported incidents of cardiovascular disease, including cardiovascular accident, transient ischemic attacks, and myocardial infarction were measured against two the neighborhood psychosocial hazards scale (NPH) and the townsend index. The NPH measures psychosocial hazards in a neighborhood such as violent crime rate and the number of off-site liquor licenses. The townsend index measures neighborhood wealth. The results of the study showed that as the psychosocial hazards in a neighborhood increased, so did the occurrence of selfreported cardiovascular events such as stroke. Conversely, as the townsend index increased, cardiovascular events decreased. The conclusion from this study is that community factors such as social norms of violence or standards of how buildings are maintained may produce a sense of alarm or threat in inhabitants. This stress may then activate a physiological stress response, leading to chronic high blood pressure or inflammatory processes that contribute to cardiovascular disease and ultimately stroke (Augustin, Glass, James, & Schwartz, 2008). Besides intrapersonal and community influences, the interpersonal level of influence can play a role in stroke. The Health and Retirement Study evaluated the STROKE: A PUBLIC HEALTH PERSPECTIVE 8 relationship between gender, marital status, cardiovascular risk factors, and stroke. Marriage is arguably one of the most dominant aspects of interpersonal influence in a person’s life. Research agrees with this statement, as people who are currently married have lower risks of stroke and stroke mortality than those who are not married. This study deduced that marriage is protective against stroke for both men and women. Financial stability was one of the variables that made an impact on the differences in risk for stroke between married and unmarried women. Unmarried women are more likely to fall into poverty and become economically vulnerable. Married men and women both benefited from the positive association between marriage and risk factors like a healthier diet and lower percentage of tobacco use. This study demonstrated that at the interpersonal level, a spouse might make have a powerful impact on his or her partner’s health. Couples may be happier, more financially stable, and act as sources of encouragement in healthy behaviors (Maselko, Bates, Avendaño, & Glymour, 2009). Much has been written about the influences that cause strokes to occur, but behavioral factors also play a role in people seeking treatment for stroke. Depending on pre-existing health conditions, some people are candidates for reperfusion therapy for ischemic stroke when admitted to the hospital. Reperfusion therapy can decrease the length of time that a portion of the brain goes without oxygen, lessening the symptoms and leading to a speedier recovery. However, many are not able to receive this therapy because they are admitted to the hospital too late after the injury has occurred. The health belief model is one tool that helps explore the reason for this problem (Mandelzweig, Goldbourt, Boyko, & Tanne, 2006). STROKE: A PUBLIC HEALTH PERSPECTIVE 9 The health belief model gives factors that establish whether a person is likely to change a behavior after being faced with a health threat. The first factor is the “extent to which the individual feels vulnerable to the threat” (Schneider, 2011). Those that feel that they have control over their symptoms, contribute their symptoms to a different etiology, or have low anxiety over the symptoms take longer to be treated (Mandelzweig, Goldbourt, Boyko, & Tanne, 2006). The second factor is the “perceived severity of the threat” (Schneider, 2011). Research shows that those with milder stroke symptoms such as dizziness or headaches take longer to seek medical attention, while those who have major symptoms like motor weakness or speech disturbance are much faster in seeking care. Those who feel that their symptoms are more commonplace and not a major medical threat are more likely to delay treatment (Mandelzweig, Goldbourt, Boyko, & Tanne, 2006). The third factor involves the barriers attributed to taking steps to reduce the risk. An example of this would be the link between being a woman and a 3-fold risk in delay of care. One of the reasons for the phenomenon is that many stroke victims are single, elderly women who may view calling family, friends, or emergency medical services as a burden, which does not outweigh her symptoms (Mandelzweig, Goldbourt, Boyko, & Tanne, 2006). The last factor, “the perceived effectiveness of taking an action to prevent or minimize the problem,” (Schneider, 2011) is illustrated by an outside influence to the stroke victim. The more that other people comment on the severity of symptoms, and encourage the person to seek medical care, the more likely that person is to go to the hospital. This interpersonal influence can help elevate the level of effectiveness that people feel they will gain from receiving treatment (Mandelzweig, Goldbourt, Boyko, & Tanne, 2006). STROKE: A PUBLIC HEALTH PERSPECTIVE 10 Biostatistical data on stroke can be very helpful for public health officials to identify the populations most at risk, and create programs that aim to reduce stroke in these groups. The Centers for Disease Control supports many public health groups and initiatives focused on reducing stroke incidence at the national, state, and local levels. For example, the Paul Coverdell National Stroke registry was created in 2001 as a statebased registry to track data on patients having an acute stroke. This data is then used to improve interventions for stroke care in eleven different states. Also, the National Heart Disease and Stroke Prevention program allots money to state health departments in fortyone states to create new policies and implement heart-healthy education programs. The WISEWOMAN program addresses the needs of women, especially those with little or no health insurance, to reduce their risk of stroke and other chronic diseases. WISEWOMAN provides screening and education to women in nineteen states and two tribal organizations (Centers for Disease Control and Prevention, 2012). Each state health department also has initiatives to combat stroke through local education programs and public awareness days. Stroke is a major concern for the public health field, as it is the fourth leading cause of death and leading cause of disability in the United States (American Stroke Association, 2013). Public health professionals should continue to provide surveillance through epidemiological and biostatistical data. Stroke is a complicated disease, with many biomedical, social, and behavioral factors. The government at all levels should continue to learn more about these factors with research, and use those findings to create policies that will ultimately decrease stroke incidence. With these policies in place and STROKE: A PUBLIC HEALTH PERSPECTIVE increased public education on the topic, the United States can be assured a healthier population. 11 STROKE: A PUBLIC HEALTH PERSPECTIVE 12 References American Stroke Association. (2013). About stroke. Retrieved from http://www.strokeassociation.org American Heart Association. (2013). Heart disease and stroke statistics-2013 update. Circulation, 127, e6-e245. Doi: 10.1161/CIR.)b)13e3182124ad Augustin, T., Glass, T., James, B., & Schwartz, B. (2008). Neighborhood psychosocial hazards and cardiovascular disease: the Baltimore Memory Study. American Journal Of Public Health, 98(9), 1664-1670. doi:10.2105/AJPH.2007.125138 Centers for Disease Control and Prevention. (2012). CDC Addresses Stroke. 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