Cloning in
Focus
What is Cloning?
An introduction to cloning and how it's done.
Click the above link:
1. Define Cloning
2. Are there currently human clones? Explain.
3. What are the two methods of cloning
4. Where does Artificial embryo twinning occur?
5. How does it occur?
6. Where are they placed?
7. What method was used to create Dolly the Sheep?
8. What is a somatic cell?
9. What do the letters in SCNT mean?
10. Describe the process of SCNT
11. What is the difference between fertilization and SCNT in regards to where the chromosomes come
from?
12. Play the fertilization video. Sketch the coloration of the offspring.
13. Play the somatic cell donor video. Sketch the coloration of the offspring.
Click and Clone
Try it yourself in the mouse cloning laboratory.
1. List the 8 things you need to clone a mouse
2. What are the 6 steps needed to clone a mouse.
3. Which Petri dish does the somatic cell go in?
4. What does the blunt pipette do?
5. What does the sharp pipette do?
6. What color is the enucleated cell?
7. What does enucleated mean?
8. How many hours does it take to reboot the DNA?
9. How many hours does it take to create 16 cells?
10. How many days does it take for the embryo to fully develop?
11. What color is the offspring mouse?
12. Did the really happen? Explain.
Why Clone?
Evaluate the reasons for using cloning technologies.
1. Which cloning purpose has the most potential benefit?
2. Often, animal models are genetically engineered to carry ___________________ .
3. Why would they do that? (Number 2 above).
4. Researchers are currently looking toward _________ as a way to create genetically defined human stem
cells for research.
5. What is “pharming”?
6. What two things would you need to revive an endangered species?
7. Can you reproduce a dead pet?
The Clone Zone
Explore the history of cloning technologies.
1. Which animal was cloned first, and when, and by whom?
2. What did Speman use to separate the cells of a salamander?
3. What did Briggs and King do? What animal did they work on?
4. Who was Dr. Bromahall? Did he allow “birth” of his experiment?
5. Who was Dr. Willadsen
6. Name the first two cloned cows?
7. What committee did Clinton form in 1995?
8. Why was Dolly different than the clones before her?
9. Who made cloning of people illegal in the US?
10. Name the first cloned mouse?
11. Who was Fibro?
12. How many attempts did it take to make Fibro?
13. Who is Zavos?
14. The Bush administration prohibited two things: Name them.
15. Who are the Raelians?
16. What role did Korea play in the cloning debate?
Cloning Myths
Separating the facts from the fiction.
1. Using three sentences: Describe Myth #1
2. Using three sentences: Describe Myth #2.
Is it Cloning? Or Not?
Test your cloning savvy with this interactive quiz.
1. Describe Scenario 1 and then give your answer.
2. Describe Scenario 2 and then give your answer.
3. Describe Scenario 3 and then give your answer.
4. Describe Scenario 4 and then give your answer.
5. Describe Scenario 5 and then give your answer.
6. Describe Scenario 6 and then give your answer.
7. Describe Scenario 7 and then give your answer.
What are the Risks of Cloning?
The predictions and realities of cloning living beings.
1. What is the success rate of SCNT?
2. List four reasons why this is so.
3. What is LOS?
4. How does the size of clone offspring compare to normal offspring at birth?
5. What are 3 potential risks associated with LOS?
6. This DNA sequences at both ends of a chromosome are called?
7. What are Telomeric differences according to age?
8. What were Dolly’s telomeric traits?
What are Some Issues in Cloning?
Answer the following 7 questions
1. Who has the right to have children, no matter how they are created? Who doesn't? Why?
2. Is human cloning "playing with nature?" If so, how does that compare with other reproductive
technologies such as in vitro fertilization or hormone treatments?
3. Does cloning to create stem cells, also called therapeutic cloning, justify destroying a
human embryo? Why, or why not?
4. If a clone originates from an existing person, who is the parent?
5. What are some of the social challenges a cloned child might face?
6. Do the benefits of human cloning outweigh the costs of human dignity?
7. Should cloning research be regulated? How, and by whom?