LAURENCE LE GRAND
539 Hinman Avenue Evanston, IL 60202
Mobile: (1) 773 946 7898 legrand_73@yahoo.fr
www.linkedin.com
CAREER SUMMARY
Over twenty years of laboratory experience in international environment
Versatile laboratory manager with deep knowledge and strong managerial experience who can provided analytical
leadership for the organization and guided strategies to enable successful business. Ability to challenge existing
organization and propose more competitive alternative to increase laboratory performance.
Excellent interpersonal skills with an ability to work individually or as a team player who built solid cross function
relationship.
Extensive experience in Project Management, industrial general practices and guidelines: ICH-FDA-USP-GMPISO, Audit: FDA-ANVISA-SuisseMedic-EMEA-COFRAC and modern laboratory principles, practices, techniques
and safety procedures.
Ability to interact and negotiate with external and internal stakeholders. Resilience to pressure, risks and complex
decision making.
Job Objective: Seeking a position as Lab Manager/Director in order to benefit years’ worth of experience to support
your organization.
PROFESSIONAL EXPERIENCE
VIFOR PHARMA:Villars sur Glane SWITZERLAND
2012 to 2014
A company of the Galenica Group, world leader in the discovery, development, manufacturing pharmaceutical
products for the treatment of iron deficiency.
Head of Analytical Development
Provide analytical leadership for the organization and launch strategies to enable successful business and optimization
of laboratory performance. Responsible for managing, coordinating, planning and monitoring all activities of the
department (validation, transfer, stability).
Responsible of all analytical support for pharmaceutical development from pre-clinical through clinical phases in a
multidisciplinary team environment.
Provide and drive constant input to maintain high quality system and performance.
Team:13
Key achievements
 Improvement of general laboratory performance ( EHS, quality, reliability)
 Restructuring of the full lab organization (22% FTE reduction)
 Implementation of:
Continuous improvement tools: 6 sigma (out of stock reduction : X2 in1 year) , Lean & 5S methodologies
Learning management system (LMS)
Enterprise Document Management System (EDMS)
Relevant KPI and Workload
Project management
Interaction with worldwide organization: technical support, Regulatory, Business Development, QA,QC..
 Standardization of cooperate analytical processes -Validation and Stability- globally.
 Audits management (internal & external): Successful interactions with FDA-ANVISA-SWISMEDIC-inspectors
 Contribution to development of new product (approval of Tecdiphera® and Velphoro®)
Tecfidera, an oral drug for treating relapsing remitting multiple sclerosis.
Velphoro, treatment of hyperphosphatemia in Chronic Kidney Disease Patients on dialysis
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GALDERMA: Alby sur Cheran FRANCE
2008 to 2012
International dermatology company dedicated to innovating skin disease solutions & aesthetic & corrective products.
Head of Analytical Development
Responsible for managing , coordinating, planning all activities of the department: validation, transfer, stability and
quality documentation to support timely development. Ensure that all the activities comply with regulations. This
includes recruiting/developing/coaching personal to ensure the efficient of the team.
Responsible for driving the organization and optimization of personnel and workflow in order to implement a new
laboratory on site (QC and Analytical Development)
Team:21
Key achievements
• Restructuring of the full lab organisation :15% FTE reduction
• Implementation of:
Continuous improvement tools: 6 sigma, Lean & 5S methodologies
Project management methodology
New technologies :Fast LC, automation of preparation..
New LIMS
Relevant KPI and Workload
• Standardization of analytical processes and procedures between analytical development and quality control
laboratories- Decrease of 38%
• Audits management (internal & external):Successful interactions with EMEA inspectors
• Improvement of general laboratory performance ( EHS, quality, reliability,)
• Cross-functional teamwork
CARSO : Le Bourget du Lac FRANCE
1991 to 2008
The CARSO group is the leading provider of analytical services in France. Environment , Agri-food
Head of Analytical Development and QC laboratories
2000 to 2008
Responsible for managing all the activities of the environmental laboratory including, analytical activities, annual
budget, communication with authorities and major customers, policies, procedures, and supervises all laboratory
personnel.
Ensure that all the activities complied with regulations and deploy resources to meet project commitment. Drive
constant improvement of quality and operating system and permanent cost reduction.
Team:28
Key achievements
• Reengineering of laboratory units to improve efficiency and develop people skills: 20% FTE reduction
• Review of employee job profile
• Implementation of
LIMS, EDMS and significant KPI
Related services including: audits, consulting, testing and sampling, etc.
Team of specialists providing scientific expertise
• Audits management (internal & external):Successful interactions with COFRAC inspectors
• Increase of productivity by 24%
• Cost reduction by 20%: maintenance lab contracts renegotiation, outsourcing of standard preparation
• Introduction new technologies :ICP-MS, Automatic preparation...
Head of Analytical development
1991 to 2000
Responsible for managing the implementation, development & optimisation of a new laboratory department.
Ensured the activities: analytical method development, validation, and that all the activities comply with regulations.
Drive constant improvement of quality and operating system.
Team:12
Key achievements
• Define & implement lab organisation (recruitment, training, equipment, lab contract..)
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Develop testing method in pesticides or chemicals under GLP system in drinking water, leisure water, surface
water, ground-water, wastewater, Soil, waste, fuels, sludge, and Emissions, ambient air, air in the work
place, etc.
Implementation of new technologies GC- HPLC-LC/MS-GC/MS-Fast-LC-Automatic extraction….
More than 800 molecules analyzed :PCB/Pesticide /HAP analysis Volatile organic compound /Semi-volatile
organic compound analysis etc..
Contact with instrument suppliers and contract labs.
Prepares/reviews/approves department documentation (e.g., SOPs, Analytical Method Validation, protocols,
and reports).
Audits management :Successful interactions with COFRAC inspectors
EDUCATION
MASTER OF CHEMISTRY, SAVOIE UNIVERSTY, Bourget du Lac, France
PRODESSIONNAL TRAINING
Management
• Appraise you team to improve your management- Repere &Vision
• How to develop assertiveness -Repere &Vision
• How to develop leadership-KenBlanchard Companies
• Skills assessment:-Afcom
Technical
• Quality Auditor - Capital & Quality consultant
• Cleaning Validation -Cefira
• Stability Study -Cefira
• Analytical Validation –Cefira
• Project Management-Internal training- L'Oréal
• Lean management and 6 sigma- Internal training- L'Oréal
LANGUAGE
English , French ( native language), and German
MISCELLANEOUS
Painting exhibitions
Hiking
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