SUSME Study Lesson Plan Title: Law of Segregation/Meiosis Authors: Lise Gelatko Falconer, LaRhonda Brown, Angela Day, Tiffany Goldsmith, Raven McDonald, Sandra McKell, Mary Moss, Pam Weaver Grade/Subject: 7/Life Science, 9th/ Pre-AP Biology Date: I. Need for this Lesson Based on teacher observations and state assessments, students do not understand Mendel’s Laws and are unable to master the associated objectives. Teacher resources are limited as well. This lesson should give students understanding of Mendel’s Law of Segregation and the Law of Independent Assortment. An understanding of meiosis is also necessary for an understanding of basic genetic principles Prior to this lesson, students should know: the parts of a cell, differences between prokaryotic and eukaryotic cells, DNA (Central Dogma), chromosome structure, mitosis, and the reproductive system. II. Unit Information A. Name of the Unit: Mendel’s Laws B. Goal(s) of the Unit: 1. Define important genetic terms 2. Illustrate Mendel’s Laws: Law of Dominance, Law of Segregation, and Law of Independent Assortment 3. Demonstrate a basic understanding of meiosis 4. Use Punnett squares to solve basic problems in genetics. C. Relationship of the Unit to the Curriculum Prerequisite Knowledge Concepts for this Unit Concepts in Future Units Students Should Know: ←Bridge from Bridge to → Prepare Students to Learn: Students should know the Students will be able to apply In high school Biology, characteristics of a cell. and define the Law of Microbiology, and Genetics, Segregation. students will discuss and Students should understand analyze various topics of DNA and the Central Students will be able to genetic engineering. In Dogma of Molecular identify that meiosis reduces middle school Life Science Biology (DNA – RNA – the chromosome number by students will discuss Protein) half examples of genetic Students should understand Students will be able to engineering. chromosome structure. identify that meiosis is the In high school biology process that produces sex Students should understand students will be expected to cells mitosis understand what happens to Students will be able to Students should understand the chromosomes during each define diploid (complete set the human reproductive phase of meiosis. of homologous system and be able to In middle school Life Science chromosomes) and haploid understand the questionand high school Biology, (half set of chromosomes) How do we reproduce? students will discuss the Students will be able to evolution as it relates to identify that meiosis is a Darwin’s theory, “survival of process that undergoes 2 the fittest.” divisions In middle school Life Students will be able to apply Science, students will discuss and define genetic life over time. terminology. In high school Biology, Environmental Science and middle school life science, students will discuss interdependent relationships of organism. D. Possible Student Misconceptions 1. 2. 3. 4. 5. 6. Students are often confused about how the autosomes work in DNA. Students do not understand the relationship between linage and genes or traits. Students are often confused about chromosome migration during cell division. Students often cannot tell the difference between homologous chromosome pairs and sister chromatid pairs. Students do not realize each parent contributes an equal number of chromosomes to their offspring. Students often cannot tell the difference between Mendel’s Law of Segregation and Mendel’s Law of Independent Assortment. E. Unit Instructional Plan: Unit Concept/Topic 1. Reproductive System- How do we reproduce? 2. Mitosis/DNA- How does a baby grow? 3. Chromosomes and Traits- Why do you look like your parents? 4. Meiosis- How do egg and sperm cells get half of the genetic information? * 5. Mendel’s Laws determine phenotypic and genotypic probabilities of offspring. * concept(s) covered in this Study Lesson Plan # of Lessons (1) (5) (4)* (1) (5) III. Study Lesson Information A. Title of the Study Lesson: Law of Segregation/Meiosis B. Standards Addressed (national, state/local): National Reproduction and heredity Grades 5-8 Molecular basis of heredity Grades 9-12 State/local Objective 7.9 ACOS Identify the process of chromosome reduction in the production of sperm and egg cells during meiosis. (from diploid to haploid) Objective 7.9.2 Contrast mitosis with meiosis Objective 7.11 Identify and explain Mendel’s Laws of Genetics: Law of Dominance, Law of Segregation, and Law of Independent Assortment Recognize genetic disorders Use monohybrid Punnett square to predict probability of offspring trait ACOS/ AHSGE High School Biology: Objective 7 Apply Mendel’s law to determine phenotypic and genotypic probabilities of offspring Define important genetic terms C. Lesson Overview: This lesson teaches students that when any individual produces gametes, the copies of a gene separate so that each gamete receives only one copy, which is the law of segregation. D. Performance Objective(s): The student will: Demonstrate meiosis and the Law of Segregation. E. Assessment Timeline Diagnostic Before student work begins. Assessment strategies, possible Formative During lesson. Assessment strategies, possible feedback, scaffolding techniques: Summative After lesson is completed. Assessment strategies, possible feedback, scaffolding techniques: feedback, remediation: Look at a picture of a family. Identify Teacher observation of how students 10 question quiz traits common to both parents. How did place the spoons, forks, and knives on child get to look like both parents? the paper plates, student answers on the student question sheet, student responses to questions asked by the teacher. F. Materials/Resources A baggie for each group containing plastic spoons, forks, and knives (pink or blue), a tri-fold board with paper plates attached, a set of vocabulary words, 4 hula hoops G. Teaching/Learning Process for the Study Lesson Step Handouts, equipment, supply. Evaluate: and time Points to remember. Assessment Teaching/Learning Activities allocation techniques for (min) each activity. Show a picture of a mother/father and child – Picture on Elmo or Class discussion Engage identify traits of the child that are common to overhead projector (5 min) mother and common to father (cartoon picture) Explore (15 min) Hula Hoop Meiosis – See teacher guide Table Top Meiosis –See teacher guide Explain (25 min) Extend (5 min) What might happen if meiosis goes wrong? What type of effect might this have on the baby? Hula hoops How "student" chromosomes separate into the different hula hoops Per group (1 tri- fold board with 8 paper plates attached “cells”, and baggie containing 4 forks, 4 spoons, 4 knives, one set of key terms Data sheet, teacher observations Teacher will demonstrate what happens when 2 chromosomes (spoons) fail to separate during meiosis. This demonstration is carried out on the display board. Student responses (Teacher can relate this to Down Syndrome, Klinefelter Syndrome, or Turner Syndrome) IV. Attachments (worksheets, labs, project guides, tests, rubrics, etc.) Use this picture to introduce the lesson: engage activity for meiosis lesson.pdf Meiosis Lesson guideline for teacher.doc Hula Hoop Meiosis Activity.doc Meiosis data table with instructions.doc meiosis vocabulary.doc meiosis vocabulary cards.doc Picture of meiosis activity poster.pdf Answer sheet for Meiosis data table.doc Meiosis assessment.doc Teacher should ask questions that are similar to the state assessment.