INSPIRE
Taster Day
Brochure
2015-2016
1
INSPIRE is a scheme supported by the Academy of Medical Sciences
and the Wellcome Trust aimed at getting medical, dental and
veterinary students involved in academic research. The Universities
of Bristol, Cardiff, Exeter and Plymouth are proud to have been
awarded grants from this body to fund research Taster Days within
prestigious research groups at the Universities. The relationships
developed during these Taster Days will ideally lead to a funded
INSPIRE vacation studentship (to be advertised later in the term) and perhaps much more.
How to apply
This brochure contains details of the Taster Days being offered
during 2015. Travel bursaries will be available to students wishing to
travel to a Taster Day in a different university to their own. To apply
for a 2015 Taster Day, please apply online via this link –
http://goo.gl/forms/ff6fHswZcg
The closing date for applications is
October 23rd 2015 at 5pm
You will be notified if you application for a taster day was successful
by the 6th November 2015.
We wish you the best of luck with your application and all future
research endeavours.
2
The INSPIRE Scheme; a student’s FAQs and guide.
1. What’s the INSPIRE Scheme?
The INSPIRE scheme is a programme run by the Academy of Medical Sciences, and
supported by the Wellcome Trust, that aims to encourage and promote medical, dental and
veterinary students to learn about and get involved in research at their own schools and
elsewhere, both in the UK and abroad.
http://www.acmedsci.ac.uk/careers/mentoring-and-careers/INSPIRE/
The current programme will run for the next two years and is organised and co-ordinated
between Cardiff, Bristol, Exeter and Plymouth schools to give students as much choice as
possible for research placements and summer project opportunities. The timetable and
deadlines for the scheme are at the bottom of the page.
2. How do I get involved?
The major parts of the scheme are research ‘Taster days’ and summer project bursaries for
students, but there are other events and programmes, such as showcase days, research
conferences, a new student-led e-magazine and an intercalators’ conference. Check out
your medical school’s INSPIRE website for details of events.
3. What are Taster Days?
These are single day visits to a research provider’s lab or group to see research first-hand.
The research taster days are advertised in October in a research booklet, students apply and
then visit the labs for a day in November or December. Applications are made through a
web-based system and you can apply and do more than one Taster day if you wish. Once
allocated, both you and the provider will be contacted. You should then make direct contact
with the provider to get more information and any background reading or arrangements for
the day.
As with any professional placement, if you cannot make the day, you MUST notify your
provider. Student ‘no-shows’ discourage research providers from getting involved in future
years!
5. What happens at the Taster day?
These days are an opportunity for you to get to have find out about the research of the
person you are visiting, also to consider whether you would like to apply for a summer
project. Do some reading before you go and talk about the research with your provider and
possible ideas and projects that would be suitable for a summer studentship. Ask them
about the context of their research and why they do it!
6. What if I then want to apply for a summer studentship?
Keep in contact with your provider and discuss what would make a good and do-able project
within the 4-6 weeks of the project. The research proposal should be written by you; you
will be sent the application forms. Bursaries are available from all 4 schools (£1000 for the
successful students.) You do not have to apply for a project in the same place you have done
your taster. See the deadlines below; no late applications will be accepted and the proposals
are judged by a student/academic panel. After you finish your project you will be asked to
write a short report; maybe even present your results at the research conference/showcase.
3
7. Can I apply elsewhere for funding?
Yes and it makes good sense to apply to more than one place. See the attached list of
potential funders, but do note they will have different deadlines and conditions for their
schemes.
Research Taster Booklet Released
October 12th 2015
Closing Date for Applications
October 23rd 2015
Students Notified of Taster Day
Allocations
Taster Day Dates
November 6th 2015
Summer project application deadline
10th March 2016
Results for project applications
24th March 2016
Summer projects
Summer 2016.
November 25th, Dec. 2nd and 9th 2015
4
University of Bristol Taster Days
MEDICAL SCIENCE-FOCUSSED RESEARCH TASTERS
1)
Research Group Bacterial Infection Lab
Name
Contact
Dr Darryl Hill – Principal Investigator (PI)
Location
School of Cellular and Molecular Medicine, Biomedical Sciences Building,
University of Bristol
Area of
Bacterial infections of the respiratory tract which lead to localised or
Research
disseminated disease such as meningitis are a considerable health and
financial burden globally. Our laboratory based research focuses on
understanding the interplay between bacteria (mainly colonisers of the
respiratory tract) and their human host during colonisation and
progression of disease. By understanding key mechanisms used by
bacteria to interact with human cells and tissues therapeutic targets can
be identified.
Number of
students and
2 students on Wednesday 2nd or 9th of December
dates available
2)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Brain Bladder Interactions
Dr Thelma Lovick (PI)
School of Physiology and Pharmacology, Biomedical Sciences Building,
University of Bristol
Urge incontinence: “a sudden and compelling desire to void which is
difficult to defer” is a relatively common condition, which is not
adequately managed. It may arise, at least in part, due to dysfunction
within the neuronal circuitry in the brain that controls bladder filling and
emptying. Using rats as models the lab is investigating how lesions of
groups of neurones the brain, of the type that occur in certain
neurodegenerative diseases in humans, impact on 24h bladder function.
We are also using rat models to investigate the potential of a closed loop
pelvic nerve stimulator for controlling bladder function.
2 students on 2nd December and 2 students on 9th December
5
3)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
4)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Bristol Renal
(Includes PIs: Prof Richard Coward; Prof Moin Saleem; Dr Seb Oltean; Dr
Simon Satchell; Dr Becky Foster; Dr Natalie Finch)
Prof Richard Coward
School of Clinical Sciences, Dorothy Hodgkin Building, University of Bristol
The molecular biology underlying kidney disease with a focus on the
glomerulus. You will be given an overview of the research we perform and
some “hands-on” experience of molecular biology techniques.
Up to 10 students on the 2nd of December.
Bristol Surgical Trials Centre
(Includes Prof Jane Blazeby (PI); Dr Kerry Avery)
Ms Kate Taylor
School of Social and Community Medicine, Whatley Rd, University of
Bristol
The Bristol Centre for Surgical Research is a multi-disciplinary
collaboration aiming to transform patient care by increasing evidencebased surgery. The centre tackles key questions relevant to patients,
clinicians and the NHS and is working to inspire and train a new
generation of surgeons to undertake high quality research. We conduct
research, including randomised controlled trials in surgery, with staff from
a wide range of disciplines and surgical specialities. This includes expertise
in trial design, consensus methods, qualitative research, medical statistics,
evidence synthesis and surgery itself. Our research tackles key questions
of relevance to patients, surgeons and to the NHS. This is an opportunity
for students to ‘shadow’ the trials-related research processes by attending
meetings where surgical trials are discussed.
2 students per research meeting.
Research meeting dates:




By-Band-Sleeve Trial Executive Group meeting: 18/11/15 (10am, Level 7,
BRI)
Bluebelle study Steering Committee meeting: 10/11/15 (Bristol – time
and location TBC).
ROMIO study Trial Executive Group meeting: 04/11/15 (time and
location TBC).
ConDuCT-II Hub for Trials Methodology Research outcomes theme
meeting: 01/12/15 (11am-2pm, Bristol).
6
5)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates
available
6)
Research
Group Name
Contact
Location
Cell Biology Lab
Professor David Stephens (PI)
School of Biochemistry, Biomedical Sciences Building, University of Bristol
Lab based molecular cell biology research. We have two major interrelated projects:
1. Molecular mechanisms of the dynein-2 cytoplasmic motor in cilia
biology.
2. Secretion of procollagen by the COPII vesicle trafficking system.
The lab itself is using high-resolution light microscopy of living cells, notably
live cell imaging, in 3D over time, to examine the organization and function
of the mammalian secretory pathway both in healthy cells as well as in
disease states. In this regard our work focusses on collagen secretion and
the formation and function of primary cilia.
For further details see: www.stephenslab.wordpress.com
Up to 2 on 25th November or 2nd December
Centre for Academic Primary Care
Area of
Research
Professor Debbie Sharp (PI)
School of Social and Community Medicine, Canynge Hall/Oakfield House,
University of Bristol
This is general practice/primary care research at its best! Answering
questions of high importance to the NHS. Using a variety of different
research methods. Please visit: www.bristol.ac.uk/primaryhealthcare/
There will be a seminar with presentations from a variety of researchers in
CAPC.
Number of
students and
dates
available
A group of not less than 6-8 students on either 25th November, 2nd
December or 9th December
7
7)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Centre for Child and Adolescent Health, Paediatric CFS/ME
Dr Esther Crawley (PI)
School of Social and Community Medicine, Oakfield House, Oakfield
Grove, University of Bristol
Paediatric trials: Testing interventions, investigating trial design including
recruitment and retention of children.
Epidemiology using ALSPAC: MRC funded research using novel causal
methodology.
Qualitative research: the impact of CFS/ME on children and families; do
children have a preference for treatment arm; how acceptable are
trials/interventions; developing an outcome measure.
Systematic reviews: Various systematic reviews investigating outcome,
treatment, experience and treatment.
The student(s) have the opportunity to take part in: qualitative analyses;
data analyses techniques; trial design; how to interview children for
qualitative research.
2 students on 25th of November or 2nd December
8)
Research Group CRIC Bristol
Name
Contact
Dr Jade Thai (PI)
Location
School of Clinical Sciences, CRICBristol, 60 St Michael's Hill, University of
Bristol
Area of
Clinical Applications of Neuroimaging
Research
Functional brain mapping studies of healthy volunteers and clinical
populations including Chronic Fatigue Syndrome and Multiple Sclerosis to
investigate the impact of fatigue on brain function.
Number of
students and
2 students on 2nd December
dates available
8
9)
Research Group Cystic Fibrosis Group
Name
Contact
Dr David Sheppard (PI)
Location
School of Physiology and Pharmacology, Biomedical Sciences Building,
University of Bristol
Area of
This group investigates the cystic fibrosis transmembrane conductance
Research
regulator (CFTR). Mutations in CFTR cause the life-shortening genetic
disease cystic fibrosis (CF). Lab-based research methods are used to
explore CFTR structure and function, learn how CF mutations cause CFTR
malfunction and investigate the mechanism of action of small-molecules
that modulate CFTR activity. These small-molecules include drugs that
target the root cause of CF by restoring CFTR expression and function and
chemicals that inhibit CFTR function, which might be used to develop new
therapies for secretory diarrhoea and autosomal dominant polycystic
kidney disease.
Number of
2 students; date to be arranged with Dr Sheppard
students and
dates available
10)
Research Group Developmental Skeletal Biology
Name
Contact
Dr Chrissy Hammond
Location
School of Physiology and Pharmacology, Biomedical Sciences Building,
University of Bristol
Area of
Regulation of cartilage and bone homeostasis in development and in
Research
disease
Number of
2 students on 2 of the dates (25th November, 2nd December and/or 9th
students and
December)
dates available
11)
Research Group Diabetes and Metabolism
Name
Contact
Dr Kathleen Gillespie (PI)
Location
School of Clinical Sciences, Learning and Research Centre, Southmead
Hospital, University of Bristol
Area of
Combination of laboratory and population-based studies focused on
Research
prediction and prevention of type 1 diabetes. This involves detection of
genetic markers and islet autoantibodies that predict future type 1
diabetes.
Number of
students and
2 students on 2nd December or 9th December
dates available
9
12)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates
available
13)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Fly Lab
Dr James Hodge (PI)
School of Physiology and Pharmacology, Biomedical Sciences Building,
University of Bristol
We are interested in the molecular mechanisms and neural circuit changes
that underlie behaviour. We are taking advantage of the fantastic genetic
toolbox available in Drosophila to tackle this problem.
We are studying age related memory decline and sleep disruption in
Alzheimer and Parkinson’s models including the effect on
neurodegeneration and movement.
For more details see: http://www.bristol.ac.uk/phys-pharm/people/jamesj-hodge/index.html
2 students on 25th November; 2 students on 2nd December; 2 students on
9th December
Glucocorticoid Lab
Dr Becky Conway-Campbell (PI)
School of Clinical Sciences, Dorothy Hodgkin Building, University of Bristol
Investigating the molecular, physiological and behavioural effects
determined by normal and dysregulated glucocorticoid exposure.
Glucocorticoids (GCs) regulate diverse physiological processes including
metabolism and immune function, as well as stress responsiveness,
cognitive processing and behavioural adaptation. Furthermore, chronic
stress, and disease states such as arthritis, depression and sleep apnea are
associated with significant alterations in the circadian GC profiles of
patients. We use a range of techniques including cell culture, molecular
techniques, histochemistry, imaging, in vivo models and behavioural
testing,
3 students on any of the dates 25th November; 2nd December; 9th
December
10
14)
Research Group IGFs and Metabolic Endocrinology Group (IMEG)
Name
Contact
Dr Claire Perks (PI)
Location
School of Clinical Sciences, Learning and Research Centre, Southmead
Hospital, University of Bristol
Area of
Laboratory based research.
Research
IMEG is focused on how nutrition and metabolism contribute to the
development of major chronic disorders, such as cancer with a specific
interest in the role of insulin-like growth factors. We particularly focus on
breast and prostate cancer.
Number of
students and
2 students on 25th November
dates available
15)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
16)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Neuroendocrinology Research Group
(PI: Prof Stafford Lightman)
Dr Francesca Spiga
School of Clinical Sciences, Dorothy Hodgkin Building, University of Bristol
Lab based research projects investigating the origin and regulation of
glucocorticoids secretion in physiological and pathological conditions.
The students may have the chance to observe a number of techniques
including hormone assay, RNA extraction, RTqPCR and Western Blotting.
1 student on 25th November; 1 student on 2nd December; 1 student on 9th
December
Neurology @ Southmead
(Includes PIs: Dr Ali Bieneman; Dr Liz Coulthard; Dr Claire Rice)
Dr Ali Bieneman
School of Clinical Sciences, Learning and Research Centre, Southmead
Hospital, University of Bristol
There are several labs based at Southmead with an interest in the
underlying mechanisms and treatment of various neurological disorders
including: Dementia; Huntington’s Disease; Parkinson’s Disease; Multiple
Sclerosis.
A group of up to 12 students on 2nd December 2-4pm.
11
17)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates
available
18)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Neuroscience @ Physiology & Pharmacology
(Including research from the labs of PIs: Prof Zaf Bashir; Dr Matt Jones; Dr
Jack Mellor; Dr Tony Pickering; and Prof Clea Warburton)
Dr Tony Pickering
School of Physiology and Pharmacology, Biomedical Sciences Building,
University of Bristol
Featuring research groups using a wide range of approaches from synaptic
and cellular to systems and behavioural neuroscience. As applied to
investigate mechanisms of learning and memory, cognition, pain
perception, neuromodulation and neural development working from the
bench-side of the translational spectrum.
(For more details see http://www.bristol.ac.uk/phys-pharm/)
Up to 12 students on 9th December
Paediatric Infection and Immunity
Prof Adam Finn (PI) and Dr Begonia Morales-Aza
School of Cellular and Molecular Medicine / School of Clinical Sciences,
Biomedical Sciences Building, University of Bristol
Immunology and microbiology of upper respiratory tract infection in
children with special reference to mechanisms of action of vaccines (which
often work by reducing transmission by inducing mucosal immune
responses). Immunological techniques used include primary human cell
culture, flow cytometric immunophenotyping, proliferation assays and
intracellular cytokine staining and immunoassays. As well as bacterial
culture, real time quantitative polymerase chain reaction is used to detect
both bacteria and viruses and the group recently began work on
microbiomic analysis using 16S ribosomal sequencing techniques. The lab
team is closely associated with a clinical studies and trials group based at
the Children’s Hospital.
2 students on each day: 25th November; 2nd December; 9th December
12
19)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Regenerative Medicine Laboratories
(Including PIs: Prof James Uney; Dr Liang-Fong Wong; Dr Oscar Cordero
Llana)
Dr Liang-Fong Wong
School of Clinical Sciences, Biomedical Sciences Building, University of
Bristol
Lab based research encompassing stem cell biology (e.g. culturing and
study of stem cells for disease modelling), molecular and cell biology of
neurodegenerative disease (e.g. investigating microRNAs in neural stem
cells, drug screening in a cell model of Parkinson’s disease) and general
neuroscience (e.g. visualising cell populations in transparent brains –
CLARITY)
Possibly 2-3 students on 2nd December; 2-3 students on 9th December
20)
Research Group Research into Safety & Quality Group (RiSQ) Group (Academic Centre of
Name
Women’s Health)
(Including PIs: Dr Christy Burden; Prof Tim Draycott; Mr Dimitrios
Siassakos;)
Contact
Dr Christy Burden
Location
School of Social and Community Medicine, The Chilterns, Southmead
Hospital, University of Bristol
Area of
Professor Tim Draycott has particular expertise in outcome based
Research
research, multi-professional training for Obstetric Emergencies, team
working and dashboards in maternity care including work in Global Heath.
Mr Dimitrios Siassakos is a member of several international academic
initiatives to improve the management of stillbirth and neonatal death
through robust research. Current work includes commissioned projects
for the Lancet stillbirth series, and research projects to inform
Department of Health task groups, national guidelines, and NIHR-funded
research.
Other areas of research include bariatric, maternal and reproductive
medicine. The research study designs undertaken vary from clinical trials
to mixed methodology & qualitative studies.
Number of
students and
dates available
1 student on 25th November; 1 student on 2nd December; 1 student on 9th
December
13
DENTAL SCIENCE-FOCUSSED RESEARCH TASTERS
21)
Research
Group Name
The Cleft Collective (Cleft lip and palate)
Contact
Ms Nicola Stock (Nicola2.Stock@uwe.ac.uk)
Location
School of Oral and Dental Sciences, Oakfield House, Oakfield Grove,
University of Bristol
Area of
Research
We have recently established a national cleft lip and palate cohort study,
which is the largest of its kind in the world. The long-term aims of the
cohort study are to improve multidisciplinary cleft care and support by
addressing three broad clinical/research questions: 1) What are the
genetic and environmental causes of cleft? 2) What are the best
treatments for cleft? 3) What is the psychological impact of cleft on the
affected individual and the family? We are also running a large Speech
and Language Study, as well as a number of smaller complimentary
projects.
Number of
students and
Up to 3 students; half a day; date to be confirmed
dates available
22)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Dental Clinical Trials Unit
Prof Nicola West (PI); Dr Maria Davies
School of Oral and Dental Sciences, Bristol Dental Hospital, University of
Bristol
The majority of our work involves the testing of newly developed products
designed to improve dental conditions such as erosion or dental
hypersensitivity. Testing may be in vitro (very new formulations) or by
means of clinical trials which may be carried out in situ or in vivo. Efficacy
of products is assessed using various measuring and imaging techniques
such as profilometry and scanning electron microscopy.
1-2 students; date to be confirmed
14
23)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Oral Nanoscience Group
Dr Michele Barbour (PI)
School of Oral and Dental Sciences, Bristol Dental Hospital, University of
Bristol
The Oral Nanoscience group is interested in the exploitation of
nanoscience and nanotechnology in dental materials and oral care
products. We are particularly interested in antimicrobial technologies, and
have recently developed a novel nanoparticulate form of chlorhexidine.
We are currently engaged in investigation of the properties of this new
material and its application in materials such as glass ionomers, bonding
materials and toothpastes. We are laboratory-based and very
interdisciplinary; current and recent group members have first degrees
which include chemistry, biomaterials science, biomedical science,
engineering, physics and microbiology as well, of course, as dentistry. You
can expect to spend your time in the lab working with our chlorhexidine
nanoparticles and investigating how these might be applied in the oral
environment.
2 students on a date in November/December.
15
VETERINARY SCIENCE-FOCUSSED RESEARCH TASTERS
24)
Research Group
Name
Contact
Location
Academic Renal Unit
Area of
Research
Dr Natalie Finch (PI)
School of Veterinary Sciences / School of Clinical Sciences, Dorothy
Hodgkin Building, University of Bristol
Lab-based research on kidney disease. The research is focussed on
glomerular endothelial cells.
Number of
students and
dates available
2 students on 25th November; 2 students on 2nd December (this session
will be combined with an overview of research from several member of
the Bristol Academic Renal Unit)
25)
Research Group AMR Force
Name
Contact
Dr Kristen Reyher (PI)
Location
School of Veterinary Sciences, Dolberry Building, Langford, University of
Bristol
We are a group of veterinarians and researchers interested in decreasing
Area of
antimicrobial use while improving animal health through a plurality of
Research
approaches. We have strong links and collaborations with social scientists along
with a track record of influencing behaviour change in animal welfare as well as
national welfare control programmes on farms. We currently are involved at a
high level in influencing the use of medicines on farms in the UK and have for the
past five years been conducting medicines audits within our practice and
reducing the use of higher level medicines on our farms. We have expertise in
policy-making as it relates to animals and their welfare, and experience in using
participatory approaches to develop policy with policy-makers, vets and farmers
and dealing with a multitude of different farming styles and attitudes.
Farm-based with subsequent lab and office-based analyses.
Number of
students and
dates available
5 students. Tuesday 1st December afternoon
16
26)
Research Group Anaesthesia and Analgesia Research Group
Name
Contact
Dr Jo Murrell (PI)
Location
School of Veterinary Sciences, Langford (Wellcome Lab), University of
Bristol
Area of
We conduct clinical type research studies to investigate fundamental pain
Research
mechanisms or the efficacy of different analgesics in clinical pain states.
The research is therefore animal based, with the majority carried out on
client owned animals and involves direct interactions with the animals to
assess pain.
Number of
students and
2 students. Date to be arranged with Dr Murrell.
dates available
27)
Research Group Animal Welfare and Behaviour
Name
Contact
Prof David Main (PI)
Location
School of Veterinary Sciences, Dolberry Building, Langford, University of
Bristol
Area of
The Animal Welfare and Behaviour groups undertakes both fundamental
Research
and applied research in a range of species including farm, companion,
equine and laboratory animals. Some of the work is undertaken at
Langford whilst many studies are conducted on commercial farms and
home environments. The research themes include understanding animal
behaviour, cognition, emotion; companion animal behaviour; welfare on
farm and implementation of welfare solutions.
Number of
Students may be able to experience specific taster experiences offered by
students and
individual members of the group (see other details) or a more generic
dates available session covering a range of research on afternoon 2nd December
28)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Animal Welfare and Behaviour
Dr Jo Edgar (PI)
School of Veterinary Sciences, Langford, University of Bristol
Research project on the use of natural maternal behaviour to improve
welfare in farmed chickens. The project may involve work with chickens
here at Langford, or on-farm study, depending on the chosen days. It will
involve behavioural observations and tests on chicks and pullets, to assess
their welfare.
1 student; date is dependent on when next study begins but can be
discussed nearer the time.
17
29)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
30)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Animal Welfare and Behaviour
Prof Christine Nicol (PI)
School of Veterinary Sciences, Langford, University of Bristol
It is essential that animal welfare indicators are valid – they should
measure something that matters to the animal, rather than being chosen
arbitrarily. Students will see ongoing experiments with laying hens,
developing new methods of validating a range of measures against hens’
own preferences and emotions.
2 students on 25th November
Bone Mechanobiology Group
Prof Jo Price (PI)
School of Veterinary Sciences, Southwell St, University of Bristol
My research group seeks to decipher the mechanisms by which
mechanical loading leads to structurally appropriate bone mass and
architecture and to establish why these mechanisms fail with ageing and
after the menopause. Our research is laboratory based and we use both in
vivo (mouse) and ex vivo models.
Two students on 9th December
31)
Research Group The Bristol Cats Study – Animal Welfare and Behaviour
Name
Contact
Dr Jane Murray (PI)
Location
School of Veterinary Sciences, Dolberry Building, Langford, University of
Bristol
Area of
The Bristol Cats Study is a longitudinal study that enables the collection of
Research
prospective data that are used for a range of epidemiological studies. The
taster day would involve students gaining experience of working with data
that are collected (e.g. owner-completed questionnaires, veterinary
histories) and the administration that is involved in running this project.
Number of
students and
4 students on 2nd December
dates available
18
32)
Research Group Equine Pain
Name
Contact
Ms Veronica Roberts (PI)
Location
School of Veterinary Sciences, Langford Equine Hospital, University of
Bristol
Area of
Trigeminal-mediated headshaking in horses. This is a neuropathic facial
Research
pain syndrome. Developing a human neuropathic pain management
technique on horses.
Number of
2-4 students. Date to be arranged with Veronica Roberts (depends on
students and
cases).
dates available
33)
Research Group Feline Infectious Diseases
Name
Contact
Dr Séverine Tasker (PI)
Location
School of Veterinary Sciences, Churchill Building, Langford, University of
Bristol
Area of
This group is involved in the laboratory investigation of feline infectious
Research
agents. A primary interest is haemotropic mycoplasmas (haemoplasmas),
which are bacterial agents that can induce haemolytic anaemia in a range
of host species. Most of our studies centre on the feline haemoplasmas
but we have carried out research on other haemoplasma species including
canine, rodent and human species. We also work on feline coronavirus
(FCoV) infection, a virus that can cause feline infectious peritonitis
(FIP). Current research involves the development of reliable diagnostic
tests for FIP, deriving genome sequences of field coronavirus isolates and
identification of feline coronavirus host receptors.
Number of
students and
2 students on 25th November
dates available
19
34)
Research Group Mucosal Immunology Lab
Name
Contact
Prof Mick Bailey (PI)
Location
School of Veterinary Sciences, Churchill Building, Langford, University of
Bristol
Area of
We carry out primarily lab-based studies on the impact of early life,
Research
particularly colonisation with commensal bacteria, on development of the
mucosal immune system. We use pigs primarily, because they are
agricultural species as well as good models for humans. In addition, we
work on swine influenza and on pig-as-biomedical-model, particularly
transplantation.
Number of
2 students, ideally together, on any of the days (25th November, 2nd
students and
December or 9th December)
dates available
35)
Research Group Mucosal Microbiology Group
Name
Contact
Dr Tristan Cogan (PI)
Location
School of Veterinary Sciences, Churchill Building, Langford, University of
Bristol
Area of
Lab-based research on the cause and control of zoonotic diseases in
Research
animals and humans, especially Campylobacter, E. coli and Leptospira.
Current projects cover pure, applied and clinical research. The group also
contains a commercial diagnostic laboratory for veterinary samples.
Current highlight areas are the diagnosis and epidemiology of Leptospira
infections in dogs in the UK; the prevalence of antibiotic resistance in E.
coli and where resistant strains can be found in the environment;
intervention strategies to prevent Campylobacter infections of chickens
and improve human health.
Number of
Up to 3 students on each of the 3 dates (25th November, 2nd December,
students and
9th December).
dates available
20
36)
Research Group “Puppies of our Time”: dog cohort study
Name
Contact
Dr Rachel Casey (PI)
Location
School of Veterinary Sciences, Dolberry Building, Langford, University of
Bristol
Area of
“Puppies of our Time” is a longitudinal study in which puppies are
Research
recruited before 16 weeks of age and followed through life. The project
enables the collection of prospective data that are used for a range of
epidemiological studies. The taster day would involve students gaining
experience of the various aspects of the project, including owner, breeder
and vet recruitment, questionnaire development, discussion about
measuring a range of health and behaviour outcomes, and some
experience of data handling.
Number of
students and
4 students on 2nd December.
dates available
37)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Spinal Cord Regeneration Lab
Dr Nicolas Granger (PI)
School of Veterinary Sciences, Langford and Biomedical Sciences Building,
University of Bristol
Research type: clinical research.
My research focuses on the development and testing of cellular therapies
for spinal cord injury repair. I focus on the use of olfactory ensheathing
cells and I am interested in optimizing this cell transplant population by: (i)
engineering cells to express molecules improving their migration and
integration within sites of spinal cord injury; (ii) designing new methods of
cell protection for efficient in vivo delivery, such as delivering cells within
hydrogels. To assess cell efficacy, I work on the canine spontaneous model
of spinal cord injury and use advanced imaging techniques, kinematic and
electrophysiology.
2 students on 2nd December
21
38)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
39)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
40)
Research
Group Name
Contact
Location
Sustainable Livestock Systems
Prof Michael Lee (PI)
Rothamsted Research, North Wyke, Okehampton, Devon, EX20 2SB
Sustainability of grazing livestock systems – the use of a BBSRC National
capability to measure the true impact (emissions, animal health) and
value (economic and social) of different ruminant livestock production
practices
A mini bus full of students between 9-11th November
Veterinary Parasitology and Ecology
Dr Eric Morgan (PI)
School of Veterinary Sciences, Life Sciences Building, University of Bristol
Parasites remain one of the most important constraints to animal health, welfare
and productivity. A detailed understanding of the biology, ecology and
epidemiology of parasites, in association with the hosts they inhabit, is essential
to allow acceptable levels of control to be achieved. We conduct laboratory and
field based research on the dynamic interactions between host and parasite
populations, and its manipulation to achieve sustainable control. Applications
include the practical diagnosis, epidemiology and control of parasites of
veterinary importance.
2 students on 25th November; 2nd December; 9th December
Wooldridge T-cell Immunology Lab
Area of
Research
Prof Linda Wooldridge
School of Veterinary Sciences, Biomedical Sciences Building, University of
Bristol
The group works on cytotoxic T-cells and the role that they play in
controlling viral infection and the natural eradication of cancer. The group
is also interested in the role that T-cells play in autoimmune disease. We
study human and animal disease including recently initiated studies on
feline coronavirus and neuroinflammatory disease in dogs.
Number of
students and
dates available
2 students – date to be confirmed
22
Cardiff University Taster Days
MEDICAL SCIENCE-FOCUSSED RESEARCH TASTERS
41)
Research
Group Name
Contact
Location
Diabetes/metabolism
Area of
Research
Prof Colin Dayan
Infection and Immunity, Cardiff University, C2 Link, Heath Park, UHW,
CF14 4XN
Protecting beta cells from immune destruction in type 1 diabetes laboratory and clinical studies. To introduce students into the different
project in the group - developing new ways to induce immune tolerance
with a "diabetes vaccine", how we develop early phase clinical trials and
studies on large cohorts of children with type 1 diabetes.
Number of
students and
dates available
4 students on 25th November 2015, 2nd December 2015, or 9th
December 2015
42)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Immunology
Prof Paul Morgan
Infection and Immunity, Cardiff University
Biomarkers and their measurement. See and learn how biologically
important molecules relevant to disease are measured and how these
measurements help predict disease.
4 students on 25th November 2015, 2nd December 2015, or 9th
December 2015
23
43)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
44)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
45)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Psychiatry
Prof George Kirov
Psychiatry, Cardiff University
Identifying new copy number variations in schizophrenia. The students
will observe our work on the analysis of genetic data from several
thousand cases and controls. The subjects have already been genotyped,
so the work will be done in offices, in front of computers. The students
will be able to familiarise themselves with some of the pitfalls and biases
that can occur in research settings of this type, the statistical methods we
use and the process of writing papers.
2 students on 25th November 2015 or 9th December 2015
Viral Immunology
Dr Eddie Wang
Infection & Immunity, Cardiff University
Modulation of host immunity by human cytomegalovirus. Introduce
human cytomegalovirus as a pathogen and its use in research as a
paradigm for immune evasion, which has aided our understanding of the
host immune system. Demonstrate assays used in our research.
3 students on 9th December 2015
College of Biomedical and Life Sciences
Dr Kathryn Taylor
School of Pharmacy and Pharmaceutical Sciences, Cardiff University
Discovery of Zinc Signalling Mechanisms in Breast Cancer. To discover
what we mean by zinc signalling and find out how zinc transporters are
important for breast cancer spread
4 students on 25th November 2015, 2nd December 2015 or 9th
December 2015
24
46)
Research Group Psychiatric genetics
Name
Contact
Dr Maria Niarchou
Location
Institute of Psychological Medicine and Clinical Neurosciences, Cardiff
University
Area of
Exploring the role of Copy Number Variants in learning disability and
Research
psychopathology in children. Results from the Experiences of CHildren
with cOpy number variants (ECHO) study. A considerable number of
studies have recently shown that specific Copy Number Variants (CNVs,
deletions or duplications of genetic material) increase risk of development
of psychiatric disorder. However, there is high variability in the phenotypic
outcomes of these CNVs and insight is very limited regarding the
mechanisms involved. The main focus of my research group is to examine
the phenotypic outcomes of individuals with Copy Number Variants in
order to obtain a better understanding of these issues. We conduct
detailed cognitive, psychiatric and genetic assessments over time of
individuals with high-risk CNVs, including children and adolescents with
22q11.2 Deletion Syndrome (22q11.2DS). The aims of the taster day are
to provide an overview of the ECHO study, describe the assessments and
data collection and discuss the ECHO study findings.
Number of
students and
2 students on 2nd December 2015 or 9th December 2015
dates available
47)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
Neurology/Immunology
Dr Mark Willis
Institute of Psychological Medicine & Clinical Neuroscience, Cardiff
University
CD8 T cells in multiple sclerosis. To experience the laboratory environment
and the interface with clinical medicine. I am a clinical research fellow in
neurology working on the role of CD8 T cells in multiple sclerosis. My work
involves patient recruitment and sample collection (cerebrospinal fluid)
through to the use of cutting edge laboratory techniques. I benefited from
time in the lab as a medical student and am keen to introduce others to
this exciting environment and the role of a clinical academic.
2 students on 2nd December 2015
25
48)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
49)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
50)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Child Psychiatry
Dr Stephen Collishaw
Psychological Medicine and Clinical Neuroscience, Cardiff University
Child and adolescent psychiatry research taster day. The aims of the taster
day are to provide an opportunity to find out more about our research.
This focuses on child and adolescent mental health. Our main areas of
interest are: child and adolescent depression, ADHD and other
developmental difficulties. We use a variety of strategies to better
understand these problems including epidemiology, genetics and
neuroimaging as well as cognitive, behavioural and clinical assessment.
We also have an interest in translating these findings into improved
patient care, for example by developing online education packages for
young people with depression.
4 students on 25th November2015 or 2nd December 2015
Cancer biology
Dr Tracey Martin
C&G, Cardiff University
Tight junction as regulators of Cancer metastasis. To see how Cell function
assays, Molecular biology and protein analysis can investigate Cancer
metastasis.
4 students on 25th November2015
Diabetes
Prof F. Susan Wong
IMEM, Cardiff University
Can autoantibody secreting cells be detected in Diabetes?
Introduction to some laboratory techniques used in investigation of
autoimmune diabetes.
2 students on 25th November2015
26
51)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
52)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
53)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Diabetes
Prof F. Susan Wong
IMEM, Cardiff University
Genetic analysis of DNA by PCR.
Introduction to some laboratory techniques used in investigation of
autoimmune diabetes.
2 students on 2nd December 2015
Diabetes
Prof F. Susan Wong
IMEM, Cardiff University
Introduction to some laboratory techniques used in investigation of
autoimmune diabetes.
2 students on 9th December 2015
PET/CT imaging / Radiochemistry
Dr Stephen Paisley
PETIC, Cardiff University
Behind the scenes introduction to the facilities and research at PETIC (the
Positron Emission Tomography Imaging Centre. PETIC runs the national
clinical diagnostic service for PET/CT in Wales and has an active many
research projects in PET tracer development. We will provide a behind the
scenes introduction to the facilities required for PET imaging (clinical and
pre-clinical imaging).
4 students on 25th November 2015, 2nd December 2015 or 9th December
2015
27
54)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
55)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
56)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Bone Biology
Dr Bronwen Evans
IMEM, Cardiff University
How does mechanical loading of bone prevent osteoporosis?
4 students on 2nd December 2015
Ionic Cell Signalling
Dr David Edwards
IMEM, Cardiff University
Forming myocytes from pluripotent stem cells
4 students TBC
Infection and Immunity
Prof Tim Walsh
Infection and Immunity, Cardiff University
Superbugs: what they are and what they do!
4 students on 9th December 2015
28
University of Exeter Taster Days
MEDICAL SCIENCE-FOCUSSED RESEARCH TASTERS
57)
Research Group Child Mental Health
Name
Contact
Prof Tamsin Ford
Location
Institute of Health Research , University of Exeter, South Cloisters, St.
Luke’s Campus
Area of
Factors influencing childhood psychiatric disorder, mental health and
Research
well-being, including interventions. We are currently running one
randomised controlled trial, a systematic review and a number of
observational studies
Number of
students and
4 students on 9th December 2015
dates available
58)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
59)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Primary Care
Prof John Campbell
Institute of Health Research, University of Exeter, Smeall Building, St.
Luke’s Campus
Primary care clinical research
4 students on 9th December 2015
Medical Imaging
Prof Karen Knapp
Medical Imaging, University of Exeter, South Cloisters, St. Luke’s Campus
We utilise medical imaging to study musculoskeletal disease processes and
investigate how to optimise imaging. We undertake experimental work
through to clinical research involving both patients and volunteers.
2 students on 2nd December 2015
29
60)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
61)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
62)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Cognitive and Behavioural Neurology
Dr Sharon Savage
Institute of Health Research, University of Exeter, College House, St Lukes
Campus
Cognitive and Behavioural Neurology
4 students on 9th December 2015
Medical Statistics
Dr Fiona Warren
Primary Care, University of Exeter, Smeall Building, St Lukes Campus
Medical Statistics
4 students on 25th November 2015
Molecular Genetics
Dr Lorna Harries
IBCS, University of Exeter, RILD building, RD7E site
My group are interested in gene expression and gene regulation,
particularly in how these mechanisms can influence human diseases. We
are a lab-based group, engaged in basic science research to uncover the
molecular causes of chronic diseases including diabetes, dementia and
ageing itself. The work uses both population-level analysis, and also
focused in vitro work to assess cause and effect and define mechanism.
Current projects include analysis of deregulation of splicing during human
ageing, functional analysis of genetic variants associated with type 2
diabetes and assessment of the effect of endocrine disrupting chemicals
on gene expression or gene regulation
4 students on 25th November 2015
30
63)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
64)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
65)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Mental Health Research Group
Prof Rose McCabe
Institute of Health Research, University of Exeter, College House, St Lukes
Campus
Communication is at the heart of all healthcare delivery. It is the means
through which diagnosis is reached and treatment is delivered. In mental
health care, it takes centre stage in the absence of physical signs and
symptoms. Moreover, the quality of healthcare professional-patient
communication influences treatment outcomes. We will introduce you to
key topics and methods in the study of communication (using real life
video recordings of doctor-patient communication in the treatment of
psychosis, depression and dementia), including our application of novel
methods such as 3D motion capture,
see http://www.youtube.com/watch?v=VxKYrZWSPJA&feature=c4overview&list=UUD7C4mz9mrgkY4chpS419dQ.
5 students on 9th December 2015
Suicide and Self Harm Research
Dr Christabel Owens
Institute of Health Research, University of Exeter, College House, St Lukes
Campus
Qualitative research, exploring suicide and self-harm from the perspective of
those who are caught up in them
5 students on 9th December 2015
Cell Biology
Dr David Allard
IBCS, University of Exeter, Medical School Building, St Lukes Campus
Tumour microenvironment
4 students on Wednesday 25th November, 2nd December or 9th December
31
66)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
67)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
68)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Implementation Science
Dr Mark Pearson
Institute of Health Research, University of Exeter, South Cloisters St Lukes
Campus
We talk a lot about evidence-based practice but how much clinical practice is
actually evidence-based? Our group brings together clinicians, managers, and
researchers to improve care by ensuring research and practice inform each
other
5 students on Wednesday 25th November
Child Health
Dr Katrina Wyatt
Institute of Health Research, University of Exeter, South Cloisters St Lukes
Campus
Development and evaluation of complex programmes to change behaviour,
including RCTs, intervention mapping and implementation design .
5 students on Wednesday 9th December
Respiratory Medicine
Dr Chris Scotton
IBCS, University of Exeter, Medical School Building, St Lukes Campus
Lung disease, particularly lung fibrosis. Our group is trying to unravel the cell
and molecular mechanisms underlying the development of lung disease, with
a view to identifying novel therapeutics, including regenerative medicine
approaches.
5 students on Wednesday 9th December
32
69)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Monogenic diabetes research group
Dr Elisa De Franco
IBCS, University of Exeter, RILD building
Genetic and genomic approaches to the identification of the genetic causes
of neonatal diabetes and hyperinsulinism.
4 students on Wednesday 2nd December
33
Plymouth University Taster Days
MEDICAL SCIENCE-FOCUSSED RESEARCH TASTERS
70)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
71)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Neurodevelopment and CNS repair
Dr. Torsten Bossing and Dr Claudia Barros
School of Biomedical and Healthcare Sciences
Understanding the workings of the human central nervous system (CNS)
with its millions of neurons generating trillions of connections is a
formidable challenge. Fortunately, to uncover the basic rules, we can turn
to simpler organisms. I am making use of the simple fruit fly Drosophila to
study evolutionary conserved mechanisms in CNS development and
disease. Using classical genetics, molecular biology, transgenics and
micromanipulation I study the embryonic development of the CNS to
understand how damage in the CNS can be repaired. I also investigate the
transcriptional program ensuring the correct formation of neural
networks
1 student on Wednesday 2nd December
Basic pathology of disorders of human nervous system
Dr Aditya Shivane
Department of Cellular & Anatomical Pathology, Derriford Hospital
Neuropathology is a highly specialized branch of histopathology which
deals with the gross and microscopic analysis of tissues of the nervous
system. Neuropathologists therefore aid clinicians in arriving at a
diagnosis. We are a small team of two neuropathologists and four
biomedical scientists incorporated in a larger histopathology department.
We collaborate with the neurosciences team in the Peninsula School of
Medicine and Dentistry on various research projects (eg. tumours of the
CNS, Parkinson disease). The aim of this taster session is to give you an
insight into the basics of neuropathology.
2 students on Wednesday 25th November, 2nd December or 9th December
34
72)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
73)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Genetic Toxicology and Ecotoxicology Research Group
Prof. Awadhesh Jha and Dr Deepu Oommen
Plymouth University; Biological Sciences
Our group works on different aspects of mutagenesis and carcinogenesis,
with particular reference to elucidation of molecular mechanisms of DNA
damage/ repair in a range of normal (e.g. cells of nervous origin) or tumor
cells (viz. ovarian and lung cancer cells) following exposure to anti-tumor
drugs or environmental agents (e.g. engineered nanoparticles).
3 students on Wednesday 25th November, 2nd December or 9th December
Hepatology Research Group
Dr Dan Felmlee
Peninsula University Peninsula School of Medicine and Dentistry
Hepatitis C virus (HCV) infects 3% of the global population and
transmitted through contaminated blood products. The majority of those
infected carry a chronic infection that leads to liver disease and hepatic
cancer. Our group previously studied of a cohort of individuals that were
exposed to HCV, but amazingly cleared the virus without showing
antibody evidence of exposure. Genetic studies of this population reveal
unique alleles in a region of anti-viral genes that may enable these
individuals to escape infection. We will pursue this investigation by
identifying other differences in sequence and testing our findings
functionally in cell culture models.
2 students on Wednesday 2nd December or 9th December
35
74)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
75)
Research Group
Name
Contact
Location
Area of
Research
Neurobiology
Dr Wai-Ling Kok
Peninsula University Peninsula School of Medicine and Dentistry
The debilitating movement symptoms in patients with Parkinson’s disease
(PD) are primarily caused by the death of dopaminergic neurons.
Understanding why these neurons die or do not function properly may
lead to new therapies for PD. Mitochondria, the powerhouses of the cell,
are highly dynamic and they undergo frequent changes in shape, size,
number and location. These dynamic processes can be controlled by
mitochondrial fission and fusion. Manipulating these processes has
considerable potential for treating human neurological conditions. One
primary interest of this laboratory is to develop therapeutic strategy for
PD by targeting mitochondrial fusion/fission.
3 students on Wednesday 25th November or 2nd December
Collaboration for the Advancement of Medical Education Research and
Assessment (CAMERA)
Dr Julian Archer and Dr Sam Regan de Bere
Peninsula University Peninsula School of Medicine and Dentistry
CAMERA brings together academic researchers, medical professionals,
educators and policy makers interested in the improvement of healthcare
through evidence-based education.
We focus on assessment and its impact across the continuum of medical
education from student selection to professional regulation. We have a
high profile in educational, regulatory and clinical literatures. We work
closely with key national institutions including the GMC and other
regulators, the Health Foundation, the Department of Health and the
National Institute of Health Research (NIHR). Our findings inform debate,
policy and practice at local, national and international levels.
Population-based research using various qualitative and quantitative
methodologies
Number of
students and
dates available
3 students on Wednesday 25th November, 2nd December 9th December
36
76)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
77)
Research Group
Name
Contact
Location
Area of
Research
Neurobiology- Understanding tumours of the nervous system.
Professor David Parkinson
Peninsula University Peninsula School of Medicine and Dentistry
Schwann cells are the glial cells of the peripheral nervous system and
provide the myelin that allows the rapid propagation of action potentials.
The loss of the tumour suppressor protein Merlin leads to the formation
of schwannomas in patients. My lab studies the biology of these tumours
using both primary human schwannoma cells and transgenic mouse
models to understand the changes in cell signaling that underlie the
uncontrolled proliferation of Schwann cells lacking Merlin.
Please see Doddrell et al (2013), Brain 136: 549-63 for details of the kinds
of research we do.
Research type: Lab based project.
2 students on Wednesday 25th November and 2 students on 9th December
Medical microbiology
Dr Mat Upton
Peninsula University Peninsula School of Medicine and Dentistry
Lab based, medical microbiology and bacterial genomics
My group is investigating the pathogenesis, epidemiology and genomics
of uropathogenic E coli (UPEC), which are the leading cause of urinary
tract infection. We are developing and commercializing rapid diagnostic
assays for UPEC.
We also carry out discovery of novel antibiotics. Lead compounds are
being developed towards clinical use for therapy of infections caused by
antibiotic resistant Gram-positive bacteria, including MRSA.
Number of
students and
dates available
2 students on Wednesday 25th November, 2nd December or 9th December
37
78)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
79)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
Clinical neurobiology
Prof Oliver Hanemann and Dr Sara Ferluga
Peninsula University Peninsula School of Medicine and Dentistry
Meningiomas are slow growing tumours of the meninges. There is no
treatment available after resection other than radiation-therapy;
therefore it is a great medical need to find new drugs to treat these
patients. We want to identify meningioma diagnostic, predictive or
prognostic biomarkers. In particular, we will analyse the
phosphoproteome from meningiomas with different genotype:
phosphoproteins present in all samples are indicative of common
upregulated pathways that could possibly be targeted. The final goal of
this project is the identification of the best suitable drug, already in
clinical trial or general practice, to target common up-regulated pathways
in meningioma patients.
2 students on Wednesday 9th December
Translational neurobiology
Prof Robert Fern
Peninsula University Peninsula School of Medicine and Dentistry
We are interested in injury to the developing white matter of the brain,
which is selectively damaged in cases of cerebral palsy; we also study
stroke injury in the brain. Projects can use electrophysiology, electron
microscopy or immuno-staining to examine an aspect of cellular injury.
This is a lab based project although there is potential for projects using CT
data from stroke patients.
2 students on Wednesday 25th November, 2nd December or 9th December
38
80)
Research Group
Name
Contact
Location
Area of
Research
Peripheral nerve regeneration group
Dr Xin-peng Dun
Peninsula University Peninsula School of Medicine and Dentistry
The peripheral nervous system differs from the central nervous system in
that it is capable of remarkable regeneration after injury, but this
astonishing regenerative capability is limited after transection injury due
to the loss of the integrity of the original axonal paths necessary for highly
efficient and accurate regeneration. In order to understand the molecular
mechanisms contributing this regenerative failure, our group is currently
using global and conditional gene knockout mouse as our research
models to study the role of several transcription factors, canonical MAPK
signalling pathways and axonal guidance molecules in peripheral nerve
repair.
Research type: Lab based project.
Number of
students and
dates available
2 students on Wednesday 25th November, 2nd December or 9th December
39
DENTAL SCIENCE-FOCUSSED RESEARCH TASTERS
81)
Research Group
Name
Contact
Location
Area of
Research
Dental and Oral Research Group
Dr. Bing Hu
Peninsula Schools of Medicine & Dentistry
The current research topics (research lab based) of my group include:
1. The molecular mechanism in controlling epithelial stem cell fate both in
development and in cancer;
2. The role of mesenchymal-epithelial interactions in organogenesis and
cancer initiation.
Number of
students and
dates available
82)
Research Group
Name
Contact
Location
Area of
Research
Number of
students and
dates available
2 students on Wednesday 25th November, 2nd December or 9th December
Tissue Engineering
Dr. Vehid Salih
Peninsula Schools of Medicine & Dentistry- Dental School
This research is totally laboratory-based and involves a variety of research
methods including 2D and 3D cell culture, a variety of microscopy, basic
molecular biology, ELISA, Histology, Flow Cytometry, Materials Testing
and Biochemical assays. My current research combines both 2D and 3D
cell culture methods to develop in vitro models and assays for diseases of
the oral tissues, in particular the oral mucosa. The work also encompasses
oral tumours and mimicking infection of in vitro mucosa to understand
the microbial and tissue interactions. I am also interested in standardizing
in vitro assays for tissue engineered scaffolds.
3 students on Wednesday 2nd December
40
83)
Research
Group Name
Contact
Location
Area of
Research
Number of
students and
dates available
84)
Research
Group Name
Contact
Location
Area of
Research
Dental and Oral Research Group
Dr. Svetislav Zaric
Peninsula Schools of Medicine & Dentistry- Dental School
Lab based and clinical research.
My research interests include microbiology of periodontal diseases, hostpathogen interactions, Toll-like receptors signalling, immunopathogenesis
of chronic inflammation and mechanisms involved in the resolution of
inflammatory response (endotoxin tolerance). I am particularly interested
in the chemical composition of Porphyromonas gingivalis LPS, with regards
to its lipid-A structure and sialylation, and in consequences these changes
have on the host’s immune response. Another area of my research
interest are molecular and cellular mechanisms responsible for tissue
injury during inflammation, identification of therapeutic targets for
resolution of inflammation and oral-systemic health connection.
5 students on Wednesday 25th November
Dental and Oral Research Group
Dr Louise Belfield
Peninsula Schools of Medicine & Dentistry- Dental School
Macrophages play a vital role in the orchestration of immune responses to
pathogenic stimuli. My research interests lie in how normal macrophage
differentiation and function may be altered in oral diseases, particularly
periodontal disease and oral cancer. Current research projects include:
-
Porphyromonas gingivalis induced macrophage effector functions and
their influence on osteoclast activity in periodontal disease
Development of an in vitro, 3-D model of the oral mucosa to study oral
cancer and stromal cell interactions
Development of an in vitro, 3-D model of the oral mucosa to study hostpathogen (biofilm) interactions.
Research type: Lab based project.
Number of
students and
dates available
2 students on Wednesday 25th November, 2nd December or 9th December
41