CLINICAL MANAGEMENT GUIDELINES Dacryocystitis (acute) Aetiology Predisposing factors Symptoms Signs Bacterial infection of lacrimal sac Usually secondary to blockage of nasolacrimal duct. Commonest in infants and post-menopausal women Relatively rare in older children Infection may be due to Gram positive or Gram-negative organisms. Staphylococcus aureus and Streptococcus pneumoniae are the most common isolates amongst Gram-positive bacteria and Haemophilus influenzae, Serratia marcescens and Pseudomonas aeruginosa amongst Gram-negative bacteria Maxillary sinusitis Trauma to adjacent tissues Nasal or sinus surgery Congenital obstruction of nasolacrimal duct (see Clinical Management Guideline on NLD Obstruction) Sudden onset Pain Tender swelling over lacrimal sac (anatomically located just below the medial palpebral ligament) Epiphora Fever (raised temperature) Red, tender swelling centred over lacrimal sac and extending around the orbit Purulent discharge expressible from one or both puncta when pressure is applied over the lacrimal sac (NB likely to be painful for patient) Sac may discharge on to skin surface (NB important to distinguish between acute dacryocystitis, in which sac is full of pus, and mucocoele in which sac is filled with mucoid material in the absence of infection) Frequently, patients may present with conjunctivitis and preseptal cellulitis. Rarely, the infection extends beyond the septum, and causes orbital cellulitis COMMENTS BY CPECG MEMBERS Dacryocystitis (acute) Version 9, Page 1 of 3 Date of search 22.05.15; Date of revision 27.05.15; Date of publication ab.cd.ef; Date for review 21.05.17 © College of Optometrists CLINICAL MANAGEMENT GUIDELINES Dacryocystitis (acute) Differential diagnosis Facial cellulitis, preseptal cellulitis, orbital cellulitis (check ocular motility and look for proptosis) (Refer to Clinical Management Guideline on Cellulitis [preseptal and orbital]) Acute frontal sinusitis (inflammation involves the upper eyelid) Infection following superficial trauma/abrasion of skin Management by Optometrist Practitioners should recognise their limitations and where necessary seek further advice or refer the patient elsewhere Non pharmacological Do not attempt to probe the lacrimal system during acute infection (risk of spreading infection) (GRADE*: Level of evidence=low, Strength of recommendation=strong) Pharmacological Topical antibiotic to prevent bacterial conjunctivitis: e.g. chloramphenicol drops and/or ointment for not less than 5 days For mild and non-febrile cases, consider prescribing systemic antibiotic, e.g. co-amoxiclav or, where there is a penicillin allergy, erythromycin (GRADE*: Level of evidence=low, Strength of recommendation=strong) A2: for severe cases and in all children, give first aid measures and refer as emergency (same day) to Ophthalmologist or A&E Department. Cases are severe if patient is febrile and/or systemically unwell or if an abscess has developed (i.e. pointing on surface) A3 (modified as condition not sight-threatening): for milder cases not responsive to systemic antibiotic, refer urgently (within one week) to ophthalmologist B3: management to resolution After acute infection has been controlled there may be an obstruction of the nasolacrimal drainage system (see Clinical Management Guideline on Dacryocystitis [chronic]) Possible management by Ophthalmologist Incision and drainage where appropriate Management Category Dacryocystitis (acute) Version 9, Page 2 of 3 Date of search 22.05.15; Date of revision 27.05.15; Date of publication ab.cd.ef; Date for review 21.05.17 © College of Optometrists CLINICAL MANAGEMENT GUIDELINES Dacryocystitis (acute) Systemic antibiotics Follow-up may include investigation and surgical intervention for nasolacrimal duct obstruction Evidence base *GRADE: Grading of Recommendations Assessment, Development and Evaluation (see http://gradeworkinggroup.org/toolbox/index.htm) Sources of evidence Pinar-Sueiro S, Sota M, Lerchundi TX, Gibelalde A, Berasategui B, Vilar B, Hernandez JL. Dacryocystitis: Systematic Approach to Diagnosis and Therapy. Curr Infect Dis Rep. 2012 Jan 29. [Epub ahead of print] LAY SUMMARY Dacrocystitis means inflammation of the tear sac, which is situated beneath the skin alongside the inner corner of the eye. It is commonest in infants and middle-aged women and is usually caused by an infection by commonly occurring bacteria (germs). It starts suddenly with pain and tenderness over the tear sac and the patient may quickly develop a fever (raised temperature). The infection may also cause conjunctivitis (infection of the white skin of the eye) and cellulitis (infection of the soft tissues surrounding the eye). Sometimes the sac bursts, releasing pus on to the skin surface. It is important to try to distinguish between this condition and orbital cellulitis itself, especially in children, who should be referred to hospital the same day for emergency treatment. Treatment includes antibiotics, which may have to be given via a needle into a vein, and surgery to encourage pus from the infection to drain away. Dacryocystitis (acute) Version 9, Page 3 of 3 Date of search 22.05.15; Date of revision 27.05.15; Date of publication ab.cd.ef; Date for review 21.05.17 © College of Optometrists