Centre for Mathematical Biology
Annual Report, July 1, 2010 – June 30, 2011
I.
Overview
During 2010-2011, the Centre was home to 2 high school students, 6 undergraduates and 21
graduate students, 4 Postdoctoral Fellows/Research Associates, 5 core faculty members and many
affiliated faculty. Again, constructive collaborations flourished with federal and provincial
governments, Mathematics in Information Technology and Complex Systems (MITACS),
NSERC networks, NGOs, industry, academic researchers within campus, and academic
researchers worldwide.
The Centre was active in hosting 26 seminar speakers, 6 short-term visitors and 4 long-term
visitors.
II.
Scientific Activities & Infrastructure
There were 5 core investigators for the Centre, (Lewis, de Vries, Hillen, Wang and Dawes). (Also
see Appendix A). Scientific activities at the Centre are defined as the activities of these core
investigators.
(a)
Current Major Multidisciplinary Research Collaborations
Ongoing and new collaborative major multidisciplinary projects are listed.
Animal Movement Modelling (AMM): This work models animal movement, using
mechanistically detailed processes describing how animals respond to environmental, resource
and conspecific cues. There are a variety of sub-projects, ranging from state space models for
wolf movement in the Alberta foothills to tracking polar bear movement over ice sheets, to more
abstract models for swarming and group formation. Centre faculty includes Hillen, Lewis and de
Vries; trainees include MSc student Rita Wong and PhD Candidates, Marie Auger-Methe and
Ulrike Schlaegel. Other participants include Eveyln Merrill and Andrew Derocher (both with
Biological Sciences). The research is funded by NSERC and PIMS. Five articles were published
during this year, two in Arctic, and the others in Marine Mammal Science, Ecology and Animal
Behaviour.
Canadian Aquatic Invasive Species Network (CAISN): This Canada-wide network of researchers
study spread and control of aquatic invaders. It involves interactions between academics and the
Department of Fisheries and Oceans and is funded by an NSERC Network grant. This network
finished in February 2011. A new network, CAISN II, has been funded by NSERC and partners at
an amount of $6,560,000 for the period of April 2011 to March 2016. Lewis and Hugh MacIsaac
are co-PIs on this grant and grad student, Harshana Rajakaruna, research associate, Alex Potapov
and postdoc, Jim Muirhead are collaborating on this project. Two articles have been published in
Diversity and Distributions and one in Ecological Modelling during this year.
Cell Movement (CM): The mathematical modelling of cell movement on petri dishes and in
tissues is a major focus of Hillen’s research. Qualitative properties of chemotaxis models have
been analysed through international collaborations with Kevin Painter, Heriot-Watt University,
Edinburgh. This research is supported through Hillen’s NSERC grant. An article has been
published this year in Physica D-Nonlinear Phenomena.
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
Contractile Forces Mediated by the Non-muscle Myosin Family of Proteins (CFMP): Many cells
require members of the non-muscle myosin (NMY) family to mediate contractile activity
involved in activities such as cell migration and membrane closure. Led by Dawes, this project
studies membrane closure in the germline cells of the nematode worm, C. elegans, using
theoretical and experimental techniques. The antagonistic forces exerted by different NMY
proteins are essential for proper cell maturation. We have extended this work to look at NMY
function in other cell types. The project is joint with Prof. David Pilgrim (Biological Sciences)
and Torah Kachur (Grant MacEwan University). This project is funded by NSERC Discovery
grants to Dawes and Pilgrim.
Coral Reef Preservation and Restoration (CRPR): This work involves investigatory preservation
and restoration of natural coral reefs using a group of newly developed refuge-dependant models.
This work involves Wang, Abhinav Singh (UK), Wendy Morrison and Howie Weiss (Georgia
Tech, Atlanta, Georgia).
Development of Instructional Modules in Mathematical Biology (IMMB); This project fits under
the auspices of the CRYSTAL-Alberta program and involves de Vries, a multidisciplinary team
of researchers from the Faculty of Science, Steve Norris (Education), mathematics teacher John
McNab (Jasper Place High School), a scientific writer Marjorie Wonham (a faculty member at
Quest). We are developing a collection of interactive web-based instructional models in the area
of mathematical biology, with the goal of conveying how mathematical techniques and
mathematical thinking contribute to contemporary scientific research in the biological and life
sciences. Our audience is primarily senior high school students and beginning undergraduate
students. Three articles were published this year in the following journals; Annual Society for
Teaching and Learning in Higher Education, Research in Science Education and Alberta Science
Education Journal.
Dynamics of Insect Populations (DIP): Mathematical modelling to investigate dynamics of insect
populations includes modelling dynamics of forest caterpillars and analysis of two-cycle
dynamics in the Rocky Mountain Apollo butterfly under climate change. Researchers include
former grad student, Jeanette Wheeler (now a PhD student at MIT), former postdocs Caroline
Bampfylde (now a research scientist with Alberta Environment) and Christina Cobbold (now a
faculty member at the University of Glasgow), Jens Roland (Biological Sciences) and Mark
Lewis. This work was continued in an international working group funded at the US National
Institute for Mathematical and Biological Synthesis (NIMBios). This research is supported
through AIF and NSERC. An article was published in Insect Science this year.
Evolution of Cell Size and Body Size (ECB): This work, led by Wang, has two subprojects:
evolution of cell sizes of phytoplankton and zooplankton with random or growth-dependent
mutations and evolution of body size phenotypes of lemmings. Graduate student, Silogini
Thanarajah, is researching this project. The project is funded by NSERC.
Ecological Stoichiometry (ES): Ecological stoichiometry is the study of the balance of energy and
nutrient elements in ecological systems. Stoichiometry theory provides an important lens to
understand and model ecological interactions with successful applications in plant-herbivore
interactions and competition for multiple nutrients. There are a variety of subprojects, ranging
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Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
from mechanistically modelling limiting factors – light and phosphorus – in algae-daphnia
microcosm experiments, and stoichiometric control of invasive daphnia species in aquatic
ecosystems, to modelling nutrient limitations on lemming population cycles in terrestrial
ecosystems. Stoichiometric modelling is a major focus of Wang’s research. Subprojects are in
progress through international collaborations, including Yang Kuang and James Elser (Arizona
State University, Tempe, Arizona), Irakli Loladze (Isreal), Xiong Li (Beijing, China), Charles
Price (University of Western Austrailia, Perth, Australia), and graduate student Silogini
Thanarajah. The research is funded by NSERC. Three articles were published this year. The first
is in the International Journal of Numerical Analysis and Modeling Series B, the second, in the
Journal of Mathematical Biology and the third, in Mathematical Biosciences and Engineering.
Forest Fire Modelling (FFM): As a result of a PIMS Industrial Problem Solving Workshop in
2006, collaboration between the Centre for Mathematical Biology (Hillen) and the Alberta
Government (Cordy Tymstra, Alberta Branch of Sustainable Resources and Development) has
developed to study models for the prediction of forest fire growth. Additional researchers include;
Rob Bryce (Programmer), Chris Bose (University of Victoria), John Braun (University of
Western Ontario, London Ontario), Dave Martell (University of Toronto), and Anne Bourlioux
(University of Montreal) This research is supported by MITACS.
F1000: Includes reviews for Faculty 1000 on new research papers. Faculty 1000 is a small group
of invited scientists that review and recommend research papers internationally. Three reviews
were completed during this year.
Habitat Destruction (HD): Wang collaborates with Fangliang He (Renewable Resources) and
graduate student Xihui (Eric) Lin, to study the number and the rank of species extinction after
habitat destruction. This project is funded by NSERC.
Infectious Disease Modelling (IDM): Modelling infectious disease transmission, led by Wang,
includes three subprojects: modelling indirectly transmitted infectious diseases such as cholera, in
collaboration with Richard Joh, Joshua Weitz and Howie Weiss (Georgia Tech, Atlanta, Georgia),
and graduate student William Davis, devising a new algorithm to recover the time-dependent
transmission rate from epidemiological data via an inverse method, in collaboration with Howie
Weiss (Georgia Tech, Atlanta, Georgia), and Mark Pollicott (University of Warwick, Coventry,
UK), abstract modelling of infectious disease transmission with waning immunity, in
collaboration with graduate student Nicholas Piazza. This work is funded by NSERC. This year,
an article was published in the American Journal of Veterinary Research.
Instream Flow Needs: A Mechanistic Model-based Approach (IFN): This project focuses on
impacts of changing water flow on the biological interactions in Alberta Rivers. It is a
collaborative venture involving researchers at the Centre: Lewis, graduate student Hannah
McKenzie, postdoc Yu Jin, and Frank Hilker (now a faculty member at the University of Bath),
and faculty members Ed McCauley (U California, Santa Barbara), Frithijof Lutscher (University
of Ottawa) and Peter Steffler (Engineering), with funding from AIF Fellowships. Funding from
an Alberta Sustainable Resource Development grant, involves additional researchers at Alberta
Fish and Wildlife. In addition, we receive major funding from the Alberta Ingenuity Water Centre
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Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
as part of a large inter-university collaborative group (Ed McCauley PI).This year, a paper was
published in the SIAM Journal on Applied Mathematics.
Maintenance of Par Protein Domains in Early Embryos of the Nematode Worm C. Elegans
(PPD): Par proteins establish distinct domains in C. elegans embryos shortly after fertilization,
although the mechanism, by which they establish and maintain those domains, is currently
unknown. By developing a mathematical model of Par protein dynamics in conjunction with
experimental work on C. elegans, a model was proposed and tested to better understand the
underlying polarization mechanism. Dawes continues to work on extensions of this model,
investigating mechanisms for symmetry breaking, in collaboration with Prof. Martin Srayko
(Biological Sciences). This project is funded by NIH and NIGMS (US) and an NSERC Discovery
Grant.
Mathematical Models for Industrial-scale Composting (MMIC): Led by de Vries, this work is in
collaboration with Daryl McCartney (Civil & Environmental Engineering) and graduate student
Anastasia Lukyanova and investigates mathematical models for industrial-scale composting
processes. The research is exploring opportunities to validate the models with researchers at the
Edmonton Waste Management Centre of Excellence.
Mathematical Models of Radiotherapy in Cancer Research (RCR): Hillen leads this study of
optimization of radiation treatment of cancer. Collaboration includes de Vries, Matthew
Parliament (Cross Cancer Institute), PhD candidate Jiafen Gong and undergraduate Chris Finlay.
The research is supported individually through NSERC projects. A paper has been published this
year, in Mathematical Medicine and Biology.
Microbiology (MB): Modelling bacterial population dynamics, behaviours and functioning is a
major focus of Wang’s research. Subprojects include; bacterial colony and community formation,
bacterial competition and coexistence, bacteria-driven organic matter decomposition and nutrient
regeneration. These subprojects are part of international collaborations that include Hal Smith,
Yang Kuang and James Elser (Arizona State University, Tempe, Arizona), Lin Jiang and Joshua
Weitz and Howie Weiss (Georgia Tech, Atlanta, Georgia), Mark Pollicott (University of
Warwick, Coventry, UK) and graduate students Silogini Thanarajah and William Davis. The
research is funded by NSERC.
Modelling of Cell Morphology (MCM): This project, led by Dawes, with graduate student Alison
Muscat, is investigating the use of simulation techniques to model cell shape changes. The
research is particularly interested in the use of level set methods to track the boundary of a
moving cell and is currently attempting to use the method to study cell blebbing, where cells
extend small rounded protrusions prior to division, and to better understand how these protrusions
are formed and regulated. Once the technique is established for blebbing cells, the investigation
will extend to study many other cell types that take on a variety of shapes in response to
environmental cues.
Modelling Primary Succession on Mount St. Helens (MSH): Since the eruption of Mount St
Helens in May 1980, researchers have been monitoring the progression of primary succession on
its slopes. Many mechanisms have been proposed to explain how primary succession unfolds,
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Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
though few have been explored in mechanistic models. Working with former MSc student, Justin
Marleau, (now a PhD student at McGill), John Bishop (Washington State University), and Bill
Fagan (University of Maryland), models have been developed to test the importance of these
mechanisms on Mount St Helens. Insights gleaned from these models could, one day, be applied
to restore ecosystems damaged by mining and natural disasters. One article has been published in
American Naturalist.
Mountain Pine Beetle Modelling (MPB): This is a collaboration between Lewis and Canadian
Forest Service scientist, Barry Cooke and research associate, Mario Pineda-Krch, as part of the
Alberta MPB Genomics TRIA Project. Other UA faculty involved in the project include; Subhash
Lele (Math & Stat Sci), David Coltman, Janice Cooke and Felix Sperling (Biological Sciences)
Myosin Regulation and Oocyte Cellularization in the Gonad of the Nematode Worm C.elegans
(MRO): During oocyte development, a ring channel is held open, allowing free movement of
components the oocytes will require to support early development after fertilization. Dawes, in
collaboration with David Pilgrim (University of Alberta) and former graduate student Torah
Kachur (now faculty at Grant MacEwan University), has used experimental and theoretical
approaches to suggest that two different myosins (nmy-1 and nmy-2) act antagonistically, to
modulate the opening of the ring channel. This project is funded by an NSERC Discovery Grant
to A. Dawes and a CIHR Operating Grant to D. Pilgrim.
Other (OTH): One article on fitting parameters of stochastic birth-death models to metapopulation
data was published in Theoretical Population Biology this year.
Polar Bear Reproductive Dynamics Under Sex-selective Harvest and Climate Change (PBR):
This collaborative research involves scientist Andrew Derocher, (Biological Sciences), former
postdoc Peter Molnar (now a postdoc at Princeton), Lewis and graduate student Marie AugerMethe. There are three projects: mathematical models to predict the effects of a sex-selective
harvest on polar bear population dynamics, mathematical models to predict the effects of climate
warming on the reproduction and body condition of polar bears, and impact of ice movement on
polar bear foraging and fitness. An article has been published in Nature Communications this
year.
Population Cycles (PC): This project focuses on impacts of physiological or behavioral
parameters and environmental factors on small mammal population fluctuations. This
collaborative research involves Wang, Olivier Gilg (Université de Bourgogne, Dijon, France),
and John Nagy (Scottsdale, Arizona). The research is funded by NSERC.
Risk Assessment of Oil Sands Related Contaminants to Aquatic Biodiversity (RAOSC): The
main goal of this project is to assess the effects environmental contaminants have on the aquatic
ecosystems and what risks are posed to individuals and populations of a variety of species within
the oil sands area of northeast Alberta. This collaborative research involves graduate student
Nicholas Piazza, Caroline Bampfylde (Alberta Environment) Wang, and Lewis. This project is
funded by Alberta Environment (Government of Alberta), and MITACS.
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Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
Sea Lice in Salmon (SLS): This work involves researchers from Alberta, Victoria, Salmon Coast
Research Station, University of Washington, Dalhousie University and Simon Fraser University.
Researchers from Alberta include, Lewis and Subhash Lele (Math & Stat Sciences), as well as
former graduate student Marty Krkosek (now a faculty member at Otago, NZ). Here, the ability to
analyze the system using mathematical and statistical models has been key in the ability to
understand complex dynamics. A project, involving graduate student, Jaime Ashander (now a
PhD student at Davis) investigated the evolutionary dynamics of sea lice under pesticide control.
Graduate student, Stephanie Peacock, is undertaking several projects assessing impact of sea lice
on conservation of wild salmon. Funding for the study comes from the International Graduate
Training Centre (IGTC) and MITACS. Two articles were published this year, one in Theoretical
Ecology and the other in Ecological Monographs.
Spatio-Temporal Dynamics of Cellular Proteins (DCP): This project aims to provide theoretical
support for the quantitative interpretation of data obtained from experiments that are designed to
probe the spatio-temporal dynamics of biomolecules such as proteins in living cells. The team
working on this project is multidisciplinary and consists of de Vries, Chris Cairo (Chemistry),
Gustavo Carrero (Athabasca), MSc students Vishaal Rajani (now a PhD student in Physiology)
and Harun Kalayci and William Davis. This group has collaborative connections to the research
group led by Dan Coombs (UBC). Funding comes from an NSERC USRA (Rajani), NSERC
Discovery grants (Cairo, de Vries), and Athabasca University (Carrero). One article was
published this year in Biophysical Journal.
Structure and Organization of Polarized Epithelial Cells (SPE): Most multicellular organisms are
constructed with polarized epithelial cell sheets. The individual cells in the sheet display unusual
structures composed of polymerized actin and tubulin filaments which are mutually regulated by
adhesion complexes. Dawes, de Vries and graduate student, Diana White, aim to use systems of
differential equations to better understand the origins and dynamics of these structures and,
ultimately, how they interact with each other to maintain polarization and proper functioning of
the epithelial cell sheet. The project is funded by an NSERC Discovery grant.
Theory of Delay Differential Equations (TDDE): This work focuses on developing new
mathematical theorems for delay differential equations with applications in biological models.
This is joint research with Wang, Edoardo Beretta (Istituto di Biomatematica Università di
Urbino, Urbino, Italy), Michael Li (Math), Yang Kuang (Arizona State University, Tempe,
Arizona), and graduate student Xihui (Eric) Lin. The work is funded by U of Alberta Startup
Funds and NSERC.
6
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
The following table summarizes the projects, researchers, trainees, publications and funding
agencies. Projects with no Centre publications are typically in their first few years, with papers
currently in the submission/review stage. Many of the projects involve additional trainees not at
the Centre. For simplicity of presentation, only the Centre trainees are shown.
Project
Senior Researchers
Dept
AMM
3
CAISN
Campus
3
Centre
Trainees
Centre
Publications
Funding
Agencies
OffCampus
7
3
2, 3, 4, 12, 13
NSERC &
PIMS
3
2
5
9, 17, 18, 24,
27
NSERC &
partners
CM
1
1
CFMP
1
CRPR
1
DCP
1
1
3
DIP
1
1
6
ECB
1
ES
1
5
FFM
1
6
F1000
2
1
20
1
NSERC
NSERC
Discovery
3
3
25
NSERC
USRA &
NSERC
Discovery
15
NSERC &
AIF
1
1
NSERC
10, 11, 28
NSERC
PIMSMITACS
Industrial
1
22, 23, 29
7
Centre for Mathematical Biology (CMB)
Project
July 1, 2010 to June 30 2011
Senior Researchers
Centre
Trainees
Centre
Publications
Dept
Campus
HD
1
1
IDM
1
IFN
1
IMMB
1
MB
1
MCM
1
MMIC
1
1
MPB
2
3
MRO
1
2
MSH
1
3
1
14
1
1
30
2
1
16
Funding
Agencies
OffCampus
1
NSERC
7
3
21
NSERC & UA
Startup
1
3
2
6
AIF
Fellowship
3
12
7
8, 19, 26
2
NSERC
1
OTH
1
1
1
1
NSERC
NSERC
Discovery &
CIHR
PBR
1
PC
1
PPD
1
RAOSC
2
1
1
RCR
2
2
2
2
NSERC
NSERC & UA
Startup
1
NIH, NIGMS
(US), NSERC
AB
Environment
& MITACS
5
NSERC
8
Centre for Mathematical Biology (CMB)
Project
July 1, 2010 to June 30 2011
Senior Researchers
Dept
Campus
Centre
Trainees
Centre
Publications
2
1, 7
Funding
Agencies
OffCampus
SLS
2
9
SPE
2
1
NSERC
Discovery
TDDE
2
1
NSERC & UA
Startup
Totals¹
40
17
86
NSERC, IGTC
& MITACS
Discovery
35
¹The units here are person times projects. In other words, individuals participating in more than
one project are counted for each project they participate in.
(b) Educational Projects and Initiatives
PIMS International Graduate Training Centre (IGTC): This program continued to flourish under
the auspices of the Pacific Institute for Math Sciences. Lewis is the Program Director of the IGTC.
Details of the program can be found at http://www.pims.math.ca/scientific/graduate-training-igtc
Mathematical Biology Journal Club: Hillen, Dawes and de Vries hosted a weekly seminar meeting
at the Centre, to discuss CMB student’s work in progress, to meet with visitors and to read
pertinent journal papers.
Wang Research Group:
Wang Research Group consists of 6 graduate students and 2 postdoctoral fellows. Besides weekly
individual meetings, they hold regular group meetings to discuss several areas of mathematical
biology as diverse as modeling stoichiometry-based ecological interactions, microbiology,
infectious diseases, habitat destruction and biodiversity, risk assessment of oil sands pollution.
Mathematical models include ODE, DDE, PDE, SDE, IDE.
Dr. Wang, his students and postdocs also had joint activities with other groups in the Centre.
Lewis Research Group:
The Lewis Research Group consists of 8 graduate students, 1 visiting summer student, 1
postdoctoral fellow and 2 research associates. Dr. Lewis and his lab members held weekly lab
meetings to discuss their research and to touch base on Centre activities. Visitors to the Centre were
invited to participate in lab meetings held during the time of their visit.
9
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
(c) Research Resources
In 2010-2011, $1271.64 was spent on toner and photoconductors for the Lexmark C534dn colour
printer in the Centre. As well, $63.00 was paid to AICT for maintenance on the same printer.
(d)
Personnel
Faculty:
There are five core faculty members (Adrianna Dawes, Gerda de Vries, Thomas Hillen, Mark
Lewis and Hao Wang).
This year, Dr. Lewis received the CRM-Fields-PIMS Prize for exceptional research in
mathematics. He was also inducted as a Fields Institute Fellow on June 27, 2011. This lifetime
appointment is granted to certain individuals who have made outstanding contributions to the
Fields Institute, its programs, and to the Canadian mathematical community.
Support Staff:
Cecilia Hutchinson continued as the Research and Administrative Coordinator of the Centre until
March 2011 and Mark Duller remains the Centre’s part-time Computer Analyst.
Graduate Students, Funding and Awards:

Jaime Ashander: MSc – graduated
Evolution and ecology of sea lice and salmon
(PIMS IGTC Fellowship in Math Biology)

Jane Cooper: MSc – continuing
The existence of cancer stem cells and their significance for tumor growth

William Davis: MSc – continuing
Indirectly transmitted infectious diseases (Nitrogen cycle modeling in aquatic environments)
(NSERC Alexander Graham Bell Canada Graduate Scholarship)

Harun Kalayci: MSc – continuing
Mathematical analysis of Single-Particle Tracking (SPT) data

Maryam Khajen Alijani: MSc – continuing
Stochasticity in modelling biological systems

Xihui (Eric) Lin: MSc – continuing
Multiple attracting limit cycles in delay differential equations

Anastasia Lukyanova: MSc – continuing
Mathematical modelling of industrial composting process
10
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
(PIMS IGTC Fellowship in Math Biology, Josephine M. Mitchell Graduate Scholarship,
Student Oral Presentation Prize (UofA))

Hannah MacKenzie: MSc – graduated
Instream flow needs and river dynamics
(Alberta Ingenuity)

Nicholas Piazza: MSc – continuing
Infectious disease modelling with seasonal incidence, vaccination and multi-cell spatial
spread

Vishaal Rajani: MSc – graduated
Mathematical methods to analyze data from single-particle tracking (SPT) experiments
(NSERC Alexander Graham Bell Canada Graduate Scholarship)

Jeanette Wheeler: MSc – graduated
Temperature-dependent population dynamics of Parnassium smintheus in Rocky Mountain
alpine meadows
(NSERC Alexander Graham Bell Canada Graduate Scholarship, Alberta Innovates
Technology Futures Scholarship)

Rita Wong: MSc – graduated
Individual-based models for animal aggregation
(NSERC Alexander Graham Bell Canada Graduate Scholarship)

Marie Auger-Methe: PhD – continuing
State –space models and the analysis movement by Arctic mammals
(Alberta Ingenuity, NSERC Alexander Graham Bell Canada Graduate Scholarship,
President’s Doctoral Prize of Distinction (UofA), Science Graduate Scholarship-UA Faculty
of Science)

Andria Dawson: PhD – continuing
Models for mixed wood forests
(Queen Elizabeth II Graduate Scholarship, MITACS/NSERC Industrial)

Jiafen Gong: PhD – continuing
Optimization of radiation treatment
(Josephine M. Mitchell Graduate Prize)

Jonathan Martin: PhD – continuing
Forest fire research
(PIMS ITGC Fellowship in Math Biology)
11
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011

Stephanie Peacock: PhD – continuing
Modelling disease transmission from aquacult to wild salmon
(Alberta Ingenuity, NSERC Alexander Graham Bell Canada Graduate Scholarship, Walter
Johns, UA MSc Scholarship, PIMS IGTC Fellowship in Math Biology)

Harshana Rajankaruna: PhD – continuing
Population viability models for invasive aquatic species

Ulrike Schlaegel: PhD – continuing
Modelling wolf movement and researching state-side models
(iCORE Graduate Recruitment Scholarship, PIMS IGTC Fellowship in Math Biology)

Silogini Thanarajah: PhD – continuing
Mathematical models for ecological dynamics
(PIMS IGTC Fellowship in Math Biology)

Diana White: PhD – continuing
Mathematical modelling of microtubule dynamics in human columnar epithelial cells
Postdoctoral Researchers, Funding and Awards:

Petro Babak: PDF – graduated
Forest fire Modelling
(PIMS/MITACS Industrial Postdoctoral Fellow)

Yu Jin: PDF – continuing
Development of mechanistic, process-oriented models for stream hydrology and biological
interactions. The goal is to understand Instream flow needs for healthy ecosystems.
Research Associates/Assistants:

Alex Potapov: Research Associate – continuing
Integrated systems for invasive species

Mario Pineda-Krch: Research Associate – continuing
Collaborative research on genomics of the Mountain Pine Beetle, in cooperation with
government and academic researchers (TRIA). Duties include modelling and model analysis
using computational and other methods.
Undergraduate Students:



Aditya Jain: BSc - continuing (MITACS Globalink)
Chris Finlay: BSc – graduated
Cole Zmurchok: BSc – continuing
12
Centre for Mathematical Biology (CMB)



July 1, 2010 to June 30 2011
Rochelle Nieuwenhuis: BSc – continuing (NSERC Undergraduate Student Research
Award)
Neil Borle: Bsc - continuing
Jeff Zielinski: Honors Thesis – graduated
High School Students:


(e)
Nadia Shardt: WISEST Summer Research Program
Emma McDonald: WISEST Summer Research Program
Visitor/Seminar Program
The Centre held the PIMS Mathematical Biology Seminar Series each Monday of the Fall and
Winter terms. Names of the speakers are listed below and include speakers from Alberta, across
Canada, the US, Europe and the Middle East.
Visiting Students:



Laura Parshotham: MSc (York University) May – August, 2011
Effects of oil sand pollution on trout fish population dynamics
Mairon dos Santos: PhD (University of Sao Paulo) – graduated
(Emerging Leaders South America)
Juan Carlos Chimal: PDF (National Polytechnic Institute, IPN) – graduated (Mexican
Fellowship)
Short-term Visitors:






Sharon Bewick (Tennessee, USA) September 20-23, 2010
Sally Otto (British Columbia, Canada) September 27 & 28, 2010
Luigi Preziosi (Torino, Italy) October 1 - 3, 2010
Leonid Hanin (Idaho, USA) November 13 - 16, 2010
Stuart Hurlbert (California, USA) December 8, 2010
Josie Hughes (Ontario, Canada) January 31, - February 4, 2011
Long-term Visitors:




Christina Surulescu (Stuttgart, Germany) August 25 - October 20, 2010
Mina Teicher (Bar-Ilan, Israel) September 28 – October 10, 2010
Kevin Painter (Edinburgh, UK) October 20 – November 9, 2010
Alan Hastings (California, USA) October 24 – November 1, 2010
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Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
Visiting Speakers from Universities other than the University of Alberta:

Sharon Bewick – University of Tennessee
A Mechanistic Approach to Modelling Ant Communities Under Warming Regimes

Sally Otto – University of British Columbia
Inferring the Past for Traits That Alter Speciation and Extinction Rates

Luigi Preziosi – Politecnico di Torino, Italy (Joint AMI/PIMS/Math Bio Seminar)
Cell Adhesion and Reorganization in a Multiphase Model Describing Tumor and Tissue
Growth

Mina Teicher – Bar-Ilan University, Israel
Synchronization in Neural Activity

Christina Surulescu – University of Stuttgart, Germany
Cell Dispersal Models: A Nonparametric Approach

Alan Hastings – UC Davis University of California (U of A Distinguished Guest
Speaker – Math Bio Seminar)
Stochastic Population Dynamics: The Role of Different Kinds of Stochasticity in Time and
Space

Alan Hastings – UC Davis University of California (U of A Distinguished Guest
Speaker – Renewable Resources Seminar)
Bioeconomics and Optimal Control of Spread of Invasive Species

Alan Hastings – UC Davis University of California (U of A Distinguished Guest
Speaker – Biology 632 Seminar)
Design of Marine Protected Area

Kevin Painter – Herriot-Watt University, Edinburgh
Integration of Theory and Experiment in Models for Embryonic Development

Leonid Hanin – Idaho State University
Distribution of the Number of Tumor Cells Surviving Fractionated Radiation

Juan Carlos Chimal – National Politechnique Institute of Mexico
Analysis and Simulation of Kinetic Models for Brain Tumor Growth

Kerry Anderson – Natural Resources Canada (NRCan-RNCan)
A Climatology Based Long-Range Fire Growth Model

Stuart Hurlbert – San Diego State University
The Logical Incoherence of Modern Statistical Practice

Josie Hughes – University of Toronto
Patterns and Processes in Outbreaking Forest Insect Population Dynamics
14
Centre for Mathematical Biology (CMB)

July 1, 2010 to June 30 2011
Jeremy Fox – University of Calgary
Evolutionary Effects of Competition Between Nutrient-Limited Consumers: On Balanced
Diets and Diversification
Seminar Speakers from the University of Alberta:

Jeanette Wheeler
Temperature Dependent Growth and Implications for Population Dynamics in an Alpine
Butterfly

Mark Lewis (A public lecture to celebrate the 100th anniversary of the Department of
Mathematical and Statistical Sciences)
Plagued by Numbers: Mathematical Insights on Disease Dynamics and Biological Invasions

Russell Greiner
Introductions to Bayesian Belief Nets

Yu Jin
Spread and Persistence of Stream Species

Alex Potapov
Modelling of Chronic Wasting Disease in Deer Population

Maryna Yaskina
Applications of Fourier Analysis to Convex Geometry

Mario Pineda-Krch
Of Speciations and Extinctions – Evolutionary Diversification and Seasonally Varying
Reproduction

Hao Wang
On the “Strict Homeostasis” Hypothesis

Russell Greiner
Towards Patient-Specific Treatment: Medical Applications of Machine Learning

Mark Lewis
Models and Data for Invasive Spread Across Lake Networks

Thomas Hillen
Cancer Stem Cells and the Tumor Growth Paradox
15
Centre for Mathematical Biology (CMB)
III.
July 1, 2010 to June 30 2011

Adriana Dawes
Par Protein Positioning in the early C. Elegans embryo

Mark Lewis (CRM, Fields, PIMS Prize Lecture)
The Mathematics Behind Biological Invasion Processes
Business Plan Implementation
(a) Space
The Centre occupies Central Academic Building (CAB) rooms 545A (visitor), 545B (director),
545C (research/admin coordinator), 545 (computing), 549 (library/meeting room) and 551
(postdoc/research associate/computer support personnel). Centre postdocs, students and visitors
are also currently using CAB 501, although this is not strictly part of the Centre. Some of the
Centre personnel are also in Lewis’ lab, Biological Sciences Building, B330
(b) Governance
Director: Mark Lewis (Math/Stat Sciences and Biological Sciences)
Advisory Board Members: Gerda deVries (Math/Stat Sciences) Russ Greiner (Computing
Science), Hao Wang (Math/Stat Sciences), Subhash Lele (Math/Stat Sciences), Jack Tuszynski
(Cross Cancer Institute)
An Advisory Board Meeting was held November 17, 2010.
(c) Financial Summary July 1, 2010 to June 30, 2011
INCOME
Source
Anticipated
Revenue
EXPENSES
Total
Revenue
Math/Stat Sci
$2,000
$2,000
Science Faculty
$58,000
$58,000
VP Research
$15,000
$15,000
TOTALS
$75,000
Source
Admin/Res
Staff
Computing
Staff
Supplies
$75,000**
TOTALS
Opening balance as of July 1, 2010 was:
$71,916.76
Closing Balance as of June 30, 2011 was:
$10,468.69*
10-11
Operating
Budget
Total Actuals
Variance
$58,500
$53,421.65
$5,078.35
$11,500
$3,749.56
$7,750.44
$5,000
$4,276.86
$723.14
$61, 448.07
$13,551.93
$75,000
*closing balance = opening balance – total expenses
**total revenue was actually received during the 2009/2010 reporting period (March, April & June 2011)
16
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
IV Evaluation of the CMB According to Established Metrics
1) Multidisciplinary Research Projects
As indicated in the footnote on Page 4, the involvement in research is measured in person times
projects.
Number of multidisciplinary
06-07
07-08
08-09
09-10
10-11
researchers
Involved in projects (in Dept.,
Campus,
And Other)
Faculty from Math & Stat Sciences,
UA
Faculty from other depts., UA
Faculty from other institutions
18
22
30
39
40
10
41
13
81
12
78
16
63
17
86
Centre trainees (grad students,
research
associates & postdocs)
Total #’s involved in
multidisciplinary
research
34 (20)
38 (19)
24¹
37¹
35¹
103
154
144
155
178
23
23
7
34
41
7
39
46
3
24
27
0
30
30
$926,187
$821,718
$759,072
$678,123
$610,136
Number and quality of papers arising
from projects
These #’s include Centre trainees and
core faculty
Book Chapters
Journal Articles
Total # of publications
Research funding arising from the
projects²
See also Formula for funding³ and
PIMS IGTC Funding4
Notes:
¹2010-11, 2009-10 and 2008-09 numbers represent Centre trainees during 2008-09 and 2009-10
and 2010-11 only. Previous years include trainees who had previously completed their training at
the Centre. Actual figures for 2006-07 and 2007-08 are now in brackets ( ).
²Yearly funding for the listed interdisciplinary research projects comes directly to the five core
faculty based on FEC reporting.
17
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
³Formula for funding: (i) use FEC reporting amounts, (ii) exclude double counting any grants
(i.e. grants that are shared by two faculty); (iii) exclude any amounts that don’t come to the U of
Alberta.
4
PIMS IGTC funding: funding from Pacific Instituite for Mathematical Sciences to support the
International Graduate Training Centre (directed by Lewis and administered from the CMB)
2) Education Initiatives
a) Number of undergrad, grad students (MSc & PhD) and postdocs trained
High School Students
Undergraduates
Graduate Students
Postdocs
Research Associates
Total students and
postdocs
b)
06-07
1
4
12
6
2
25
07-08
0
2
11
7
1
21
08-09
0
5
14
4
2
25
09-10
2
7
21
5
2
37
10-11
2
6
21
2
2
33
Quality of training, awards and recognition of students, placements of students and postdocs
A major educational initiative is the International Graduate Training Centre (IGTC) in
Mathematical Biology. This is allowing us to recruit and support more high quality students.
c)
Awards, Fellowships & Graduates
Awards received by
graduate students
Number of graduating
students
06-07
11
07-08
22
08-09
33
09-10
32
10-11
26
2
3
3
1
5
3) Visitor Program
a) Number of visitors/seminar speakers
PIMS MathBio Seminar Speakers Worldwide
PIMS MathBio Seminar Speakers from the U
of Alberta
Long and Short Term Visitors
Total Number of Visitors
06-07
16
7
07-08
18
7
08-09
15
12
09-10
13
13
10-11
14
12
1
24
1
26
13
40
14
40
10
36
Out of town visitors were scheduled to meet with students, postdocs and faculty to discuss
mutual research topics.
18
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
4) Outreach
On September 7, 2010, Dr. Wang gave a short talk, “My first year experience,” in the 2010 Science
New Faculty Orientation. In May, 2011, he visited Beijing Normal University, to discuss possible
collaborations with professors and graduate students in the Mathematics department. Dr. Wang was
one of two organizers for the session, “Dynamical Systems,” in the CMS Summer Meeting at the
University of Alberta in June.
Dr. de Vries is very involved with the WISEST Summer Research Program. She served as Role
Model in July, and a Panelist and Keynote Speaker in August She also assisted in the design and
development of the Decima Robinson Support Cenre for Mathematical and Statistical Sciences.
This initiative allows the department to better serve the needs of the undergraduate students.
Dr. de Vries helped with consolidating the textbook and online homework systems for the
engineering and non-engineering calculus streams by negotiating the terms of agreement with the
publishing company on behalf of some 4000 students and instructors per year.
19
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
APPENDIX A
Major Stakeholders and terms of reference
Individual Researchers:
1)
Core faculty during the 2010-11 period were;
 Adriana Dawes
 Gerda de Vries
 Thomas Hillen
 Mark Lewis
 Hao Wang
Core faculty use the Centre, typically, on a daily basis and run Centre activities. They, their students
and postdocs, define the Centre and its initiatives. They have access to Centre facilities including;
computing resources, library, and office space for postdocs and visitors.
2) Associated faculty in mathematical biology in Mathematical & Statistical Sciences;
 Herb Freedman
 Subhash Lele
 Michael Li
These faculty members use the Centre occasionally and typically interact with core faculty (above)
on some of the Centre activities and research. Centre resources are available to the associated faculty
on a request basis.
3)
Associated faculty in mathematical biology across campus with some interactions at the Centre;
 Evelyn Merril, Biological Sciences
 Andrew Derocher, Biological Sciences
 Jens Roland, Biological Sciences
 David Coltman, Biological Sciences
 Janice Cooke, Biological Sciences
 Felix Sperling, Biological Sciences
 David Pilgrim, Biological Sciences
 Martin Srayko, Biological Sciences
 Chris Cairo, Chemistry
 Peter Steffler, Engineering
 Fangliang He, Renewable Resources
This list is flexible and changes over time.
Interactions with associate faculty range from collaboration in multidisciplinary research groups, to
being regular participants in Centre activities. These faculty members do not typically have access to,
or need for, Centre resources; however, they benefit through the scientific and collaborative
interactions.
20
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
APPENDIX A (Continued)
4)
Institutions which support the Centre through funding and administration:
 Department of Mathematical and Statistical Sciences
 Faculty of Science
 Mathematics of Information Technology and Complex Systems (MITACS) NCE
 Pacific Institute for Mathematical Sciences (PIMS)
 Vice President of Research Office
Support from these institutions is vital for the success of the Centre. The Department of
Mathematical and Statistical Sciences, the Faculty of Science and the VP Research Office contribute
the core funding of the Centre. Administration of the Centre falls within the Department of
Mathematical and Statistical Sciences and the Faculty of Science. PIMS and MITACS support
Centre activities (such as the Undergraduate Summer Workshop, internships, etc.) The institutions
benefit from the scientific and educational activities in the Centre.
5) Affiliated research groups who benefit from their association with the Centre:
These include researchers/research groups, external to the University of Alberta, that are involved in
the multidisciplinary research projects.
Project
AMM
CAISIN
CM
CFMP
CRPR
IMMB
DCP
DIP
ECB
ES
FFM
HD
IDM
IFN
Researchers/Research Group
Marianne Marcoux (McGill University), Hal Whitehead (Dalhousie University), G.
Larocque, Pierre. Dutilleul (McGill University), Murray.M. Humphries (McGill
University), E. Chmelnitsky, S. Ferguson
Hugh MacIsaac, C. Diabacco
Kevin Painter, (Heriot-Watt University, Edinburgh)
Torah Kachur, (Grant MacEwan University)
Abhinav Singh, (UK), Wendy Morrison, (Georgia Tech, Atlanta Georgia), Howie
Weiss (Georgia Tech, Atlanta, Georgia)
John McNab (Jasper Place High School), D. Laurie, D. Vallee, B. Bahnmann, S.
Yiu, P. Lu, N. Stelnicki, J. Braga, Marjorie Wonham, (Quest)
Gustavo Carrero (Athabasca), Dan Coombs (UBC), David E. Golan (Harvard)
Jeanette Wheeler, (MIT), Caroline Bampfylde, (Alberta Environment), Christina
Cobbold, (University of Glasgow), Stephen F. Matter (University of Cincinnati), A.
Doyle
Yang Kuang (Arizona State University, Tempe, Arizona), James Elser (Arizona
State University, Tempe, Arizona), Irakli Loladze (Isreal), Xiong Li, (Beijing,
China), Charles Price, (University of Western Australia, Australia)
Cordy Tymstra (Sustainable Resources and Development) Rob Bryce, Chris Bose
(University of Victoria), John Braun (University of Western Ontario), Dave Martell
(University of Toronto), Anne Bourlioux, (University of Montreal)
Richard Joh (Georgia Tech, Atlanta, Georgia), Joshua Weitz (Georgia Tech,
Atlanta, Georgia), Howie Weiss, (Georgia Tech, Atlanta, Georgia), Mark Pollicott
(University of Warwick, UK) J. O`Brien, C. Thunes, T.E. Carpenter
Frank Hilker (Bath), Ed McCauley (Santa Barbara, California), Frithijof Lutscher
21
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
(Ottawa)
PPD
MMIC
RCR
MB
MCM
MSH
MPB
MRO
OTH
PBR
PC
RAOSC
SLS
Matthew Parliament (Cross Cancer Institute) Mairon do Santos (University of Sao
Paulo)
Yang Kuang (Arizona State University, Tempe, Arizona), James Elser (Arizona
State University, Tempe, Arizona), Lin Jiang (Georgia Tech, Atlanta, Georgia),
Joshua Weitz (Georgia Tech, Atlanta, Georgia), Howie Weiss, (Georgia Tech,
Atlanta, Georgia), Mark Pollicott (University of Warwick, UK)
Justin Marleau (McGill), John Bishop (Washington State), Bill Fagan (U of
Maryland)
Barry Cooke (Canadian Forest Services)
Torah Kachur (Grant MacEwan)
Heinrich zu Dohna
Peter Molnar (Princeton), T. Klanjscek
Olivier Gilg (Université de Bourgogne, Dijon, France), John Nagy (Scottsdale,
Arizona)
Caroline Bampfylde (Alberta Environment)
Marty Krkosek (Otago, New Zealand), B.M. Connors (SFU), H. Ford (U Victoria),
P. Mages, J.S. Ford (Dalhousie University), A. Morton (Salmon Coast Research
Station), J.P. Volpe (U Victoria), R. Hilborn (U Washington), L.M. Dill (SFU)
SPE
TDDE
22
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
APPENDIX B
Metrics for Evaluating the Centre for Mathematical Biology
1. Multidisciplinary Research Projects
 Number of multidisciplinary researchers involved in projects (in Dept., on Campus or
Other)
 Number and quality of papers arising from projects
 Research funding arising from projects
2. Educational Initiatives
 Number of undergrads, grad students (MSc and PhD) and postdocs trained
 Quality of training, awards and recognition of students, placements of students and
postdocs
3. Visitor Program
 Number of visitors/seminar speakers
4. Outreach
Outreach is communication of Centre research and educational endeavours to individuals
who do not typically participate in the same or similar activities. Groups of these individuals
include, but are not restricted to;
i. Media
ii. School groups
iii. The general public
23
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
APPENDIX C
Centre Publications (trainees in bold)
1. Ashander, J. Krkosek, M., Lewis, M.A. (2011) Aquaculture-induced changed to dynamics of
migratory hosts and specialist parasite: A case study of pink salmon and sea lice. Theoretical
Ecology 5(2):231-252
2. Auger-Méthé, M., Marcoux, M., and Whitehead, H. (2010). Nicks and notches of the dorsal
ridge: promising mark types for the photo-identification of narwhals. Marine Mammal Science
26: 663-678
3. Auger-Méthé, M., St. Clair, C.C., Lewis, M.A., Derocher, A.E. (2011) Sampling rate and
misidentification of Lévy and non-Lévy movement paths: comment Ecology 92(8):1699-1701
4. Auger-Méthé, M., Marcoux, M., Whitehead, H.(2011). Computer-assisted photoidentification of
narwhals. Arctic 64: 342-352
5. Gong, J., dos Santos, M.M., Finlay, C., Hillen, T.J. (2011) Are more complicated tumor
control probability models better? Mathematical Medicine and Biology – A Journal of the IMA
39 pages
6. Jin, Y., Lewis, M.A. (2010) Seasonal Influences on population spread and persistence in streams
II: Critical domain size. Siam Journal on Applied Mathematics 71(4):1241-1262
7. Krkosek, M., Connors, B.M., Ford, H., Peacock, S., Mages, P., Ford, J.S., Morton, A., Volpe,
J.P. Hilborn, R., Dill, L.M., Lewis, M.A. (2011) Parasitism, predation, and pink salmon
population dynamics. Ecological Monographs 21:897-914
8. Lawrie, D., Vallee, D., Bahnmann, B., Varnhagen, C., Loppnow, G.R., Gallin, W.J., Yiu, S., Lu,
P., Konhauser, K.O., de Vries, G., Sydora, R.D. (2011) Innovations in integrated first year
science laboratories. Annual Society for Teaching and Learning in Higher Education Conference
Saskatoon, Canada.
9. Lewis, M.A., Jerde, C. (2010) Invasion Biology. Sourcebook in Theoretical Ecology
10. Li, X., Wang, H. (2010) A stoichiometrically derived algal growth model and its global analysis.
Mathematical Biosciences and Engineering 7:825-836
11. Li, X., Wang, H., Kuang, Y. (2011) Global analysis of a stoichiometric producer-grazer model
with Holling-type functional responses. Journal of Mathematical Biology 63(5):901-932
12. Marcoux, M., Larocque, G., Auger-Méthé, M., Dutilleul, P., Humphries, M.M. (2010).
Statistical analysis of animal observations and associated marks distributed in time using
Ripley’s functions. Animal Behaviour 80: 329-337
13. Marcoux, M., Auger-Méthé, M., Chmelnitsky, E., Ferguson, S., Humphries, M.M.
(2011).Local passive acoustic monitoring of narwhal presence in the Canadian Arctic: a
pilotproject. Arctic 64:307-316
14. Marleau J.N., Jin, Y., Bishop, J., Fagan, W.F., Lewis, M.A. (2011) A Stoichiometric model of
early plant primary succession American Naturalist 177:233-245
15. Matter, S.F., Doyle, A., Illerbrun, K., Wheeler, J., Roland, J. (2011). An assessment of direct
and indirect effects of climate change for populations of the Rocky Mountain Apollo butterfly
(Parnassius smintheus Doubleday). Insect Science 18, 385-392.
16. Molnár, P.K., Derocher, A.E., Klanjscek, T., Lewis, M.A. (2011) Predicting climate change
impacts on polar bear litter size. Nature Communications 2:186
24
Centre for Mathematical Biology (CMB)
July 1, 2010 to June 30 2011
17. Muirhead, J., Lewis, M.A., MacIsaac, H. (2010) Prediction and error in multi-stage models for
spread of aquatic invasive species. Diversity and Distributions 17(2):323-337
18. Muirhead, J. R. and MacIsaac, H.J. (2011). Evaluation of stochastic gravity model selection for
use in estimating non-indigenous species dispersal and establishment. Biological Invasions 13:
2445–2458.
19. Norris, S.P., Stelnicki, N., de Vries, G., (2011) Teaching mathematical biology in high school
using adapted primary literature. Research in Science Education 42(4):633-649
20. Painter, K., Hillen, T.J. (2010) Spatio-Temporal Chaos in a Chemotaxis Model. Physica DNonlinear Phenomena 240:363-375
21. Pineda-Krch M., O’Brien J., Thunes C., Carpenter T.E. (2010). Potential impact of an
introduction of foot-and-mouth disease from wild pigs into commercial premises in California.
American Journal of Veterinary Research 71:82—88.
22. Pineda-Krch, M., Lewis, M.A. (2010) Evaluation for Regime shifts in ecological systems can
occur with no warning. Ecology Letters Vol. 13. Faculty of 1000 Post-Publication Peer Review
23. Pineda-Krch, M., Lewis, M.A. (2011) Evaluation for Predator-induced defense makes Daphnia
more vulnerable to parasites. Evolution Vo. 65. Faculty of 1000 Post Publication Peer Review
24. Potapov, A., Muirhead, J.M., Lele, S.R., Lewis, M.A. (2011) Stochastic gravity models for
modeling lake invasions. Ecological Modelling 22:964-972
25. Rajani, V., Carrero, G., Golan, D.E., de Vries, G., Cairo, C.W. (2011) Analysis of molecular
diffusion by first-passage time variance identifies the size of confinement zones. Biophysical
Journal 100:1463-1472
26. Stelnicki, N., Braga, J., de Vries, G., Norris, S.P. (2011) Using Adapted Primary Literature to
teach high school science. Alberta Science Education Journal 41:11-15
27. Strasser, C., Dibacco, C., Lewis, M.A. (2011) A mechanistic model for understanding invasions
with environment as a predictor of population success. Diversity and Distributions 17(6):12101224
28. Wang, H. (2010) Revisit brown lemming population cycles in Alaska: examination of
stoichiometry. International Journal of Numerical Analysis and Modeling, Series B, 1:93-108
29. Wang, H., Lewis, M.A. (2011) Evaluation for “Do invasive species show higher phenotypic
plasticity than native species and, if so, is it adaptive? A meta-analysis. Ecology Letters Vol 14.
Faculty of 1000 Post-Publication Peer Review
30. zu Dohna H., Pineda-Krch M. (2010). Fitting parameters of stochastic birthdeath models to
metapopulation data. Theoretical Population Biology 78: 71—76.
25