Welcome to CNIB’s InFocus Webinar Series Webinar 1: Diabetic Retinopathy Basics Presented by: Netan Choudhry M.D. FRCS(C) Date: 25th October 2012 Start Time: 1:00 pm EST CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 2: Diabetic Retinopathy Basics: Objectives Participants will be able to learn about: Anatomy of the eye What is Diabetic Retinopathy Signs and Symptoms Types of Diabetic Retinopathy Risk Factors and Prevention Diagnostic Tests Treatment Frequently Asked Questions 2 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 3: The Anatomy of the Eye The Retina – senses light and transmits images to the brain The Macula – central part of the retina used to read and see fine details clearly The Vitreous – clear gel fills the back of the eye and sits in front of the retina Figure 1: The Human Eye 3 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 4: What is Diabetic Retinopathy? Occurs when elevated blood sugar levels cause blood vessels in the eye to swell and leak into the retina. Figure 2: Diabetic macular edema (swelling of the retina) 4 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 5: Signs and Symptoms Floaters Blurred vision Fluctuating vision Blank or dark areas in field of vision Poor night vision Vision loss Figure 3: Normal Vision Figure 4: How vision may be affected by diabetic retinopathy 5 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 6: Types of Diabetic Retinopathy Early stages: Non-Proliferative Diabetic Retinopathy (NPDR) Damaged blood vessels in the retina begin to leak fluid and small amounts of blood and cholesterol. Mild NPDR may not necessarily affect vision. Results of blurred vision: Fluorescein dye leaking in macula Figure 5: Macula edema Figure 6: Fluorescein angiogram of macula edema 6 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 7: Types of Diabetic Retinopathy Late stages: Proliferative diabetic retinopathy (PDR) Retinal vessels close causing significant reduction in blood flow. The retina responds by growing new abnormal vessels. Can affect both central and peripheral vision. Vitreous hemorrhage New blood vessels bleed into vitreous cavity. Tractional retinal detachment Scar tissue can shrink causing the retina to detach and result in vision loss. More severe vision loss occurs if the macula is detached. Figure 7: Tractional retinal detachment 7 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 8: Risk Factors/Prevention Uncontrollable Diabetes type Ethnicity Controllable High blood sugar Smoking High blood pressure High cholesterol Obesity Early detection via eye exams is paramount Type 1 diabetes: within 5 years of diagnosis, then annually Type 2 diabetes: at time of diagnosis, then annually Gestational diabetes: within 1st trimester 8 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 9: Diagnostic Tests Basic assessment Visual acuity test Tonometry: Measures pressure inside the eye Dilated eye exam Advanced assessment Fluorescin angiogram: dye is injected systemically which demonstrates retinal circulation Optical coherence tomography (OCT): non-invasive imaging study that reveals retinal anatomy Figure 9: Optical coherence tomography (OCT) Figure 8: Fluorescein angiogram 9 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 10: Treatments Proliferative retinopathy Laser surgery • Microscopic thermal laser burns are made in the retina • Shrinks and prevents abnormal new blood vessel growth, and stops leaking of blood vessels • Can reduce risk of further vision loss by 50% • Also recommended to treat macular edema Figure 10: Laser photocoagulation 10 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 11: Treatments Proliferative retinopathy Intraocular (anti-VEGF) injections • Reduces swelling in the retina and causes abnormal vessels to regress Figure 11: Intraocular injection 11 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 12: Treatments Diabetic macular edema Lucentis • Health-Canada-approved anti-VEGF treatment • Approved for reimbursement in Quebec only 12 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 13: Treatments Advanced proliferative retinopathy Vitrectomy • Cloudy vitreous is removed and replaced with a clear solution that mimics the normal eye fluids • Allows light rays to focus on the retina again Figure 12: Pars Plana Vitrectomy 13 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Slide 14: Eye Connect: Diabetic Retinopathy cnib.ca/dr - Diabetic retinopathy basics - Prevention - Diagnosis and treatment - Living with diabetic retinopathy - Health care professionals’ page - Patient guide 14 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Final - Slide 15: CNIB Contacts and Resources • CNIB website: cnib.ca • Toll-free CNIB Helpline: 1-800-563-2642 • Email: info@cnib.ca Production of this material has been made possible through a financial contribution from the Public Health Agency of Canada. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada. 15 CNIB In Focus Webinar 1: Diabetic Retinopathy Basics Web: cnib.ca Email: info@cnib.ca CNIB Helpline: 1-800-563-2642 16