Protein Requirements in Acute Care: NCM, Escott-Stump, & Krause. Acute encephalopathy: Begin at .5 g/kg and progress as tolerated to 1-1.5 (this is not a contraindication for adequate protein administration). WITH coma, use 0.5 – 0.6 g/kg, and advance to 1-1.5 g/kg (euvolemic wt) If using parenteral nutrition, can use 1-1.5 g/kg immediately d/t avoidance of gut bacteria Acute Respiratory Distress Syndrome 1.5-2 g/kg of actual body weight Age (55+ years) 1.2-1.5 g/kg to reduce sarcopenia Alcoholic Liver Disease 1.5 g/kg if malnourished Ascites 1.5 g/kg Amputations Emphasize proteins of high biological value, especially for short-term. Adhere to wound protein guidelines. Bed Rest 1.2 g/kg Burns 25 kcal/kg – 30 kcal/kg ----- BEE * 1.3-1.4 1.5-2.0 g/kg protein Should be 20-25% of needs 1.2 g/kg of actual body weight for burns less than 10%, or for obese patients 1.5-3 g/kg body weight depending on burn extent Bronchitis Normal protein requirements Bleeding Disorders Ensure a diet rich in protein, iron, copper, B vitamins, folid acid, B12 Cancer Intake should be high: 11.5 g/kg to maintain, 1.5-2 g/kg to gain Cardiac Cachexia 1-1.5 g/kg (increase or decrease dependent on renal/hepatic status) Cardiomyopathies 1-1.5 g/kg (increase or decrease dependent on renal/hepatic status) Celiac Disease 1-2 g/kg for adults Cholestasis (acute) 0.5-1.2 g/kg Crohn’s Disease WITH strictures/fistulas, 11.5 g/kg Chronic Kidney Disease Stages 1, 2, 3: Limit protein to 12-15% (0.8-1 g/kg) Stage 4, reduce to 10% (0.6 g/kg, with 50% from high biological value sources) WITH HEMODIALYSIS 1.2 g/kg WITH PERITONEAL DIALYSIS 1.2-1.3 g/kg, with peritonitis 1.5 g/kg until infection subsides Colostomy Increased protein needs depending on protein malabsorption, decrease intake, etc. COPD 1.2-1.7 g/kg (high protein, high-fat, high calorie diet) Critical Care (hemo stable) For patients with a BMI of 30-40, 2.0 g/kg of IBW Patients with BMI of greater than 40, at least 2.5 g/kg IBW All others: 1.2-2.0 g/kg actual body weight Cushing’s Syndrome 1 g/kg if losses are excessive Cystic Fibrosis Protein should be 10-35% of calories o 4 g/kg for infants o 3 g/kg for children o 2 g/kg for teens o 1.5 g/kg for adults Diabetes Type 1 To reduce the risk of nephropathy, keep protein intake to the RDA 1 g or less per kg body weight is recommended but should not go below 0.8 g/kg. Diabetes Type 2 With normal renal function, 15-20% of kcals With impaired renal function, control at 0.8-1 g/kg Respiratory Failure w/ Vent 1.2-1.5 g/kg (Mechanick and Chiolero, 2008) Lung Transplant Post-op: 1.3-1.5 g/kg Fat Malabsorption Disorders Increase protein requirements but do not use protein bound to fat (e.g. Eggs with yolk, meat, etc.) Fractures 20-25% kcal needs Gastric Bypass, Post-op 1.5-2 g/kg Include 60-80 g protein per day Gestational Diabetes Regular intake. 20% total kcals. RDA during pregnancy is 1.1 g/kg or at leats 56 g protein Giant Hypertrophic Gastritis/Menetrier’s Disease High-protein diet comprising 20% of kcal Gout Ileostomy high-energy, highprotein diet Refeeding Syndrome Start protein slowly – 1.21.5 g/kg goal Kidney disease, glomerular and autoimmune Stage 1-4 not on dialysis: 0.6-0.8 g/kg o GFR < 20 not on dialysis: 0.3-0.5 g/kg Stage 5 HD: >1.2 g/kg Stage 5 PD: > 1.2-1.3 g/kg Surgery In general, 1-1.5 g/kg for wound healing (dependent on extent of catabolism and surgical intervention) Kidney Transplant, stable 0.8-1 g/kg Liver Transplant 0.8-1 g.kg dry wt in compensated liver disease 1.5-2 g/kg dry wt in decompensated Malaria and Parasitic Anemias High protein diet Eat a moderate amount of protein. Avoid animal sources of protein (to reduce purine load) during flare ups. During remission, consume a general diet as tolerated. Heart Failure “HF patients have significantly higher protein needs than those without HF.” Malnutrition, general 25-35% Multiple Organ Dysfunction Syndrome 1.2-1.5 g/kg Short Bowel Syndrome: Start with 1.2-1.5 g/kg then keep at 20% kcals Trauma 1.5-2 g/kg Renal transplant Immediately after, 1.3-2 g/kg , then 0.8-1 in the chronic phase Ulcerative Colitis May be restricted in renal disease, but generally 1-1.5 g/kg as long as patient is progressing UTI Nephrotic syndrome 0.8 g/kg Oncology Patients will require highprotein meals. Hepatitis (acute) 1-1.2 g/kg Pancreatitis (acute) 1.2-1.5 g/kg Hepatic Cirrhosis 1-1.5 g/kg of highquality protein Pancreatitis (chronic) 1-1.5 g/kg HIV/AIDS 2-2.5 g/kg, may increase with fever and infection Polycystic kidney disease Meet RDA unless proteinuria is excessive Hyperthyroidism Correct negative nitrogen balance. 1-1.75 g/kg Sepsis 1.5-2 g/kg Underweight with unintentional weight loss 15-20% Restrict ONLY if renal function is decreased. Otherwise, use proteins of high biological value Whipple’s Disease High protein, highcalorie diet General Guidelines Protein is usually 0.8-1 g/kg to maintain status 1.25 g/kg mild stress 1.5 g/kg moderate stress 1.75-2 g/kg for severe stress, trauma, burns