SCRIPT NUMBER 149 GOITER - 2 (TWO SPEAKERS) PROGRAM NAME: HEALTH NUGGETS PROGRAM TITLE: GOITER - 2 PROGRAM NUMBER: 149 SUBJECT: CAUSES, SYMPTOMS, DIAGNOSIS, TREATMENTS OF GOITER KEY WORDS: THYROID GLAND, HORMONES, DIETARY IODINE, IMMUNE, RADIATION DATE OF SCRIPT: JANUARY 31, 2014 AUTHOR: RICHARD YUKL, MD, FACS SPEAKER 1: Anna is 55 year old woman. She looked into a mirror one day to see if aging was causing the skin of her face to wrinkle, and she noticed swelling in the lower part of her neck just above her breastbone. The swelling enlarging over the next several months, and it seemed to harden as it enlarged. She sought the advise of a doctor when she began having some trouble swallowing. The doctor diagnosed Anna as having a goiter, an enlargement of her thyroid gland. SPEAKER 2: Your thyroid is a butterfly-shaped gland located in the front part of your neck just above your breastbone. Doctors call any enlargement of the thyroid gland a goiter, whatever its cause. A goiter may be particularly obvious to a man when he shaves, or to a woman when she puts on makeup. Large goiters can be seen as a swelling at the base of the neck. They usually cause no symptoms, not even pain, although they can cause distressing symptoms such as tightness in the throat, trouble swallowing, coughing, scratchiness of the voice, and even problems with breathing. SPEAKER 1: What does a thyroid do? SPEAKER 2: The thyroid was created to regulate some essential functions of our body. It makes chemicals called hormones that control our heart rate, our temperature, and the rate at which our body converts the food we eat into energy. Many people think that if they are developing enlargement of their thyroid, there is something wrong with the gland. However, their thyroid may be working properly even if a goiter develops. It may still be producing normal amounts of hormones. SPEAKER 1: Who develops a goiter and why does it happen? SPEAKER 2: Goiters can develop in anyone at any time. They can be present at birth, although they most commonly develop after age 50. The most common cause is a lack of iodine in the diet. The thyroid needs iodine to produce its hormones, and that Iodine is found in seawater and in soil found near the oceans of the world. People who live far from an ocean or at high elevations often don’t get enough iodine in their diet, and their thyroid enlarges in an effort to make normal amounts of hormones. Iodine is routinely added to the table salt sold in many countries today, as well as to many foods. Still, there are areas of the world in which people don’t get enough iodine to satisfy their body’s needs, especially in the countries of central Asia, central Africa, and in the Andes Mountains of South America. SPEAKER 1: In addition to a lack of iodine, what other conditions could cause me to develop a goiter? SPEAKER 2: We were created with a sophisticated immune system designed to destroy foreign proteins that attack our body – proteins such as those found in invading bacteria and viruses. There are times when, for reasons scientists still do not understand, this immune system is tricked into thinking our thyroid gland is a foreign invader, so it attempts to kill it, causing a goiter to develop. Other risk factors include being a woman, pregnancy and aging. Risk also increases if you are a heavy smoker, or if you've had radiation to your neck or chest as a treatment for cancer. SPEAKER 1: How is a goiter treated? SPEAKER 2: Treatment is not always necessary. It depends on the size of the goiter, your symptoms, and the underlying problem that caused your thyroid to enlarge. Someone who develops serious symptoms will need treatment of course, but small goiters that aren't noticeable and don't cause physical symptoms usually don't need treatment. The main concern related to a small goiter causing no symptoms is to be certain the swelling is not a cancer. Most goiters are noncancerous, and they don't lead to cancer. In one study, only one in 13 patients with thyroid enlargement was found to have cancer. SPEAKER 1: How is a goiter diagnosed? SPEAKER 2: Your doctor will test your blood to determine if your thyroid produces normal amounts of hormones, and if your immune system is producing chemicals that destroy your thyroid. If worrisome abnormalities are felt on examination, a needle will be used to take a sample of the abnormality for microscopic examination. SPEAKER 1: Will I need surgery? SPEAKER 2: Surgery will be required if cancer is found, but your doctor will usually recommend thyroid hormone replacement pills as treatment for noncancerous goiters, even if they are large or causing distressing symptoms. That will allow your thyroid to rest, and it may become smaller. If replacement pills don’t relieve the symptoms, the doctor will then recommend surgery to remove part or all of the enlarged gland, making for more room in your neck. That will make breathing and swallowing easier. People who need but cannot tolerate surgery can be given radioactive iodine to destroy the thyroid gland. SPEAKER 1: How was Anna’s goiter treated? SPEAKER 2: It was developing worsening symptoms. It showed no evidence for cancer, but it didn’t respond to her taking thyroid replacement pills, and removal of a portion of her gland was required to relieve her swallowing problem. She did not need to take thyroid replacement pills following her surgery. SPEAKER 1: How can I prevent developing a goiter? SPEAKER 2: If you live at a distance from the ocean or at high altitude, buy and use salt to which iodine has been added, or eat seafood or seaweed about twice a week. Since too little iodine in the diet is the major cause of developing a goiter, this simple change may be very helpful. Otherwise, your doctor is best qualified to decide on the proper treatment. SPEAKER 1: Health Nuggets is written by Dr. Richard Yukl, a medical doctor working in the United States. The medical views expressed in this program are his and may differ for your particular health needs. If you need medical advice, please consult a medical professional in your area.