BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME Levit, Rebecca Diane eRA COMMONS USER NAME (credential, e.g., agency login) POSITION TITLE Assistant Professor, Division of Cardiology RDIANE EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.) DEGREE INSTITUTION AND LOCATION MM/YY FIELD OF STUDY (if applicable) BS 05/02 Biology -- 06/03 Fulbright Fellow MD 05/07 Medicine Emory University, Atlanta, GA Resident 06/09 Internal Medicine Emory University, Atlanta, GA Research Fellow Cardiology Fellow 06/12 Cardiovascular Disease 06/14 Cardiovascular Disease Dickinson College, Carlisle, PA University of Wollongong, NSW, Australia University of Pennsylvania, Philadelphia, PA Emory University, Atlanta, GA A. Positions and Honors Positions and Employment 2002-2003 Fulbright Fellow, Biological Sciences, University of Wollongong, NSW, Australia 2003-2007 Medical Student, University of Pennsylvania School of Medicine, Philadelphia, PA 2007-2009 Resident, Internal Medicine Research Track, Emory University, Atlanta, GA 2009-2012 Research Fellow, Cardiology Research Track, Emory University, Atlanta, GA 2012-2014 Clinical Fellow, Cardiovascular Diseases, Emory University, Atlanta, GA 2014-Present Assistant Professor, Division of Cardiology, Emory University, Atlanta, GA Other Experience and Professional Memberships 2006Member, American Heart Association 2009Member, American College of Cardiology 2010 Scientific Writer, NIH working committee, New Dimensions and Strategies for Women’s Health 2010-2014 American Heart Association Working Committee on Cardiovascular Disease and Stroke in Women and Special Populations Board Certification 2010-2020 Certified, American Board of Internal Medicine, Internal Medicine 2014 Candidate, American Board of Internal Medicine, Cardiovascular Disease 2014-2024 Certified, National Board of Echocardiography, Adult Echocardiography 1 Honors 2013 2012 2012 2012 2011 2009 2006 2003 Featured Research, Emory University Department of Medicine Research Day, Atlanta, GA Finalist, Early Career Investigator Award, American Heart Association’s Council on Arteriosclerosis, Thrombosis and Vascular Biology, Los Angeles, CA 1st place, Basic Science Prize, Northwestern Cardiovascular Young Investigators' Forum, Chicago, IL 2nd place, Emory University Cardiology Research Symposium, Atlanta, GA 1st place, Emory University Cardiology Research Symposium, Atlanta, GA American Heart Association Women in Cardiology Trainee Award for Excellence, Orlando, FL George W. Householder, III Memorial Prize for medical student research, University of Pennsylvania School of Medicine, Philadelphia, PA Fulbright Fellow, University of Wollongong, NSW, Australia B. Selected Peer-reviewed Publications Most relevant 1. Levit RD, Landázuri N, Phelps EA, Brown ME, García AJ et al. Cellular encapsulation enhances cardiac repair. Journal of the American Heart Association. 2013; 2(5):e000367. PMID: PMC3835246. 2. Landázuri N*, Levit RD*, Joseph G, Ortega-Legaspi JM, Flores CA, Weiss D, et al. Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine-mediated vascular recovery after hindlimb ischaemia. Journal of Tissue Engineering and Regenerative Medicine. 2012. PMCID: PMC23281223. *Shared first co-authorship 3. Han JW, Levit RD, Yoon Y-s. Induced Pluripotent Stem Cells. In: Kong HJ, Putnam AJ, Schook LB, editors. Stem Cells and Revascularization Therapies. 1 ed. Boca Raton, Florida: CRC Press; December 13, 2011. p. 55-105. 4. Kim S-W, Kim H, Cho H-J, Lee J-U, Levit RD, Yoon Y-s. Human Peripheral Blood-Derived CD31+ Cells Have Robust Angiogenic and Vasculogenic Properties and Are Effective for Treating Ischemic Vascular Disease. Journal of the American College of Cardiology. 2010;56(7):593-607. PMCID: 2917842. 5. Hiesinger W, Perez-Aguilar JM, Atluri P, Marotta NA, Frederick JR, Fitzpatrick JR, McCormick RC, Muenzer JR, Yang EC, Levit RD et al. Computational Protein Design to Reengineer Stromal Cell–Derived Factor-1α Generates an Effective and Translatable Angiogenic Polypeptide Analog. Circulation. 2011;124(11 suppl 1):S18-S26. PMCID: PMC21911811. 6. Atluri P, Panlilio CM, Liao GP, Hiesinger W, Harris DA, McCormick RC, Cohen JE, Jin T, Feng W, Levit RD et al. Acute Myocardial Rescue with Endogenous Endothelial Progenitor Cell Therapy. Heart, Lung and Circulation. 2010;19(11):644-54. PMCID: PMC3235678. 7. Hiesinger W, Vinogradov SA, Atluri P, Fitzpatrick JR, Frederick JR, Levit RD, et al. Oxygen-dependent quenching of phosphorescence used to characterize improved myocardial oxygenation resulting from vasculogenic cytokine therapy. Journal of Applied Physiology. 2011;110(5):1460-5. PMCID: PMC3098666. Additional recent publications (in chronological order) 1. Levit RD, Levit RD, Polomsky M, Vega JD, Martin DR, Kumar G. An unusual cause of a non-ST segment elevation myocardial infarction. Heart. 2014; PMID: 24855318 2. Levit RD, Titterington JS, Wenger NK. Stable Ischemic Heart Disease in Women. In press. 3. Levit RD and Wenger NK. High Risk, High Stakes: Optimizing Cardiovascular Risk Assessment in Women. Cur Cardiol Risk Report. 2012; 6 (2): 176-184. 4. Levit RD, Taylor WR. A Clinical Commentary on the Article “N-acetylglucosamine Conjugated to Nanoparticles Enhances Myocyte Uptake and Improves Delivery of a Small Molecule p38 Inhibitor for Postinfarct Healing”. Journal of Cardiovascular Translational Research. 2011;4(5):644-5. PMCID: 21850557. 5. Levit RD, Reynolds HR, Hochman JS. Cardiovascular Disease in Young Women: A Population at Risk. Cardiology in Review. 2011;19(2):60-5 10.1097/CRD.0b013e31820987b5. PMCID: 21285664. 6. Levit RD, Cohen RM, Kwak A, Shlansky-Goldberg RD, Clark TWI, Patel AA, et al. Asymptomatic Central Venous Stenosis in Hemodialysis Patients1. Radiology. 2006;238(3):1051-6. PMCID: 16424248. 2 C. Research Support Emory Office of Technology Transfer Proof of Concept Fund A purpose built device to deliver stem cells in biomaterials to the heart Role: PI 07/25/14 – present 14SDG18530001 01/01/14 - present AHA Scientist Development Grant (Percentile 1.43%, Average priority score 1.21) Encapsulated mesenchymal stem cells as therapy for ischemia-reperfusion via neutrophil regulation Role: PI T32 5T32HL007745-18 07/01/09-06/29/12 Research Training in Academic Cardiology While a research fellow I developed encapsulation technology to improve retention of viable stem cells in the heart post-myocardial infarction in animal models. Role: Trainee T35 DK060441 10/01/06-02/01/07 NIH/NIDDK Medical Student Training Grant Gene therapy for myocardial infarction using an adenoviral vector to over-express cell cycle genes in periinfarct cardiomyocytes in animal models. Role: Trainee Fulbright Fellowship 07/01/02-06/29/03 Role of polyunsaturated fatty acids in lifespan and metabolism of aging vertebrates Role: PI 3