Sheraton Gunter Hotel Program (update 12/1) December 4, 2011 Tutorial Session Chair: Dr. Jianhua Ruan, University of Texas at San Antonio Room: Alamo 1. Systems Biology in Epigenetic Regulation Presenter: Dr. Yunlong Liu, Assistant professor, Department of Medical and Molecular Genetics, Indiana University School of Medicine Dr. Kun Huang, Associate professor, Department of Biomedical Informatics, the Ohio State University Time: 1:00 pm to 3:00 pm 3:00 pm to 3:30 pm 2. Break Ion Torrent – Open, Accessible, and Enabling Presenter: Matt Dyer, Ph.D. Ion Torrent, Sr. Product Manager, Bioinformatics & Community Time: 3:30 pm to 5:30 pm 6:00 pm to 8:00 pm Reception at Biga on the Banks December 5, 2011 Plenary Talks Room: Alamo 7:50 am Opening remark 8:00 am to 8:45 am Plenary talk 1 Chair: Dr. Yidong Chen Personalizing Cancer Medicine: Bioinformatics and the Omic Revolution 8:45 am to 9:30 am Plenary talk 2 Chair: Dr. Fuli Yu Unstable DNA and Human Disease: Fragile X syndrome and FXTAS 9:30 am to 9:50 am Break & posters 9:50 am to 10:35 am Plenary talk 3 Chair: Dr. Kun Huang Dr. John N. Weinstein Professor and Chair, Department of Bioinformatics and Computational Biology, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center Dr. David Nelson Professor, Department of Molecular and Human Genetics, Baylor College of Medicine Integrative Analyses of Methylome, Cistrome, and Chromatin Interactome Dr. Tim Huang Professor and Chair, Department of Molecular Medicine Deputy Director, CTRC University of Texas Health Science Center at San Antonio Main Sessions Session: 1 Next Generation Sequencing for Epigenetic Research Chairs: Dr. Yunlong Liu, Assistant professor, Department of Medical and Molecular Genetics, Indiana University School of Medicine Dr. Kun Huang, Associate professor, Department of Biomedical Informatics, the Ohio State University Time: 10:40 am to 12:00 am Room: Alamo 1. A Scalable, Flexible Workflow for MethylCap-Seq Data Analysis Benjamin Rodriguez1, Hok-Hei Tam1, David Frankhouser1, Michael Trimarchi1, Mark Murphy1,Chris Kuo1, Deval Parikh1, Bryan Ball1, Sebastian Schwind1, John Curfman1, William Blum1, Guido Marcucci1, Pearlly Yan1,Ralf Bundschuh2 1. The Ohio State University Comprehensive Cancer Center Columbus, Ohio, USA, 2. Departments of Physics and Biochemistry, Center for RNA Biology, The Ohio State University Columbus, Ohio, USA. 2. An ERŒ±/Modulator Regulatory Network in the Breast Cancer Cells Heng-Yi Wu1, Yu Wang1, P. Zheng1, G. Jiang1,Yunlong Liu1,Kenneth P. Nephew2,Tim H. M. Huang3, Lang Li4 1.Center for Computational Biology and Bioinformatics Indiana University Indianapolis, Indiana USA 2.Medical Sciences, School of Medicine Indiana University Bloomington, Indiana USA 3.Department of Molecular Virology, Immunology, and Medical Genetics The Ohio State University Columbus, Ohio USA 4.Department of Medical and Molecular Genetics Indiana University Indianapolis, Indiana USA. 3. Empirical Bayes Model Comparisons for Differential Methylation Analysis Mingxiang Teng1, Yadong Wang1,Curt Balch2, Kenneth P. Nephew2, Yunlong Liu3, Lang Li4, Seongho Kim5 1.School of Computer Science and Technology Harbin Institute of Technology Harbin, Heilongjiang, China 2.Medical Sciences Indiana University Bloomington, Indiana, USA 3.Department of Medicine, Indiana University Indianapolis, Indiana, USA 4.Department of Medical and Molecu-lar Genetic, Indiana University Indianapolis, Indiana, USA 5.Department of Bioinformatics and Biostatistics University of Louisville, Louisville, Kentucky, USA. 4. Chromatin signature analysis and prediction of genome-wide novel promoters using finite mixture model Cenny Taslim1, Shili Lin1, Kun Huang2, Tim Huang3 1.Department of StatisticsColumbus, OH 43210, USA. 2.Department of Biomedical Informatics, Columbus, OH 43210, USA. 3.Department of Molecular Virology, Immunology and Medical GeneticsColumbus, OH 43210, USA. Session: 2 Gene Regulation Network I Chair: Dr. Erchin Serpedin, Texas A&M University Time: 9:50 am to 11:50 am Room: Baker 1. Uncertainty-based Essentiality in Gene Regulatory Networks Xiaoning Qian1, Byung-Jun Yoon2and Edward R. Dougherty2,3,4, 1. Dept. of Computer Science & Engineering, University of South Florida, Tampa, FL 33620 2. Dept. of Electrical & Computer Engineering, Texas A&M University, College Station, TX 77843 3. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ 85004 4.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030 2. The effect of certain Boolean functions in stability of networks with varying topology Vitor H. P. Louzada1, Ronaldo F. Hashimoto1,Fabr´ıcio M. Lopesy2. 1.Institute of Mathematics and Statistics of the University of S˜ao Paulo, Brazil 2.Federal University of Technology - Paran´a, Brazil 3. A Cubature Kalman Filter Approach for Inferring Gene Regulatory Networks Using Time Series Data Amina Noor1, Erchin Serpedin1, Mohamed Nounou2and Hazem Nounou2 1.Department of Electrical and Computer EngineeringTexas A&M University, College Station, Texas 77843. 2. Texas A&M University at Qatar, Doha, Qatar 23874. 4. A novel critical time analysis approach for Genetic Regulatory Networks Sonal Bhattacharya, Ranadip Pal Electrical and Computer Engineeirng Department, Texas Tech University, Lubbock, TX, USA 1:20 pm to 2:00 pm Dr. Ray Jacobson Round Table with funding agencies Scientific Review Officer Bioengineering Sciences and Technologies Center for Scientific Review National Institutes of Health Room: Alamo Session: 3 Computational Methods for Therapeutic Chair: Dr. Ronaldo F. Hashimoto, University of Sao Paulo Time 2:00 pm to 4:00 pm Room: Alamo 1. Efficient Combinatorial Drug Optimization Through Stochastic Search Mansuck Kim, Byung-Jun Yoon Department of Electrical and Computer Engineering Texas A&M University. 2. A novel approach for tumor sensitivity prediction and combination therapy design for targeted drugs Noah Berlow,Ranadip Pal. Texas Tech UniversityLubbock, TX, 79409, USA. 3. Modeling Cyclic and Acyclic Therapeutic Methods with Persistent Intervention Effect in Probabilistic Boolean Networks Mohammadmahdi R. Yousefi1, Aniruddha Datta1, Edward R. Dougherty1,2,3 1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA. 2.Comp. Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA. 3.Dept. of Bioinf. and Comp. Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. 4. Predicting Drug Efficacy Based on the Integrated Breast Cancer Pathway Model Hui Huang1, Xiaogang Wu1, Sara Ibrahim2 , Marianne McKenzie3, Jake Y. Chen4 1.School of Informatics, Indiana University. 2. School of Medicine Indiana University. 3. School of Science Purdue University. 4. School of Informatics Indiana University. 5. Identifying Genes Associated with Chemotherapy Response in Ovarian Carcinomas Based on DNA Copy Number and Expression Profiles Fang-Han Hsu1, Erchin Serpedin1, Tzu-Hung Hsiao3, Alexander J.R. Bishop3,4,Edward R. Dougherty1,2,Yidong Chen3,5 1.Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX. 2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ. 3.Greehey Children’s Cancer Research Institute. 4.Department of Cellular and Structural Biology. 5.Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, TX. 6. Assessing the Efficacy of Molecularly Targeted Agents by Using Kalman Filter Xiangfang (Lindsey) Li, Lijun Qian, Michael L. Bittner, and Edward R. Dougherty Session: 4 Gene Regulation Network II Chair: Dr. Nevenka Dimitrova, Philips Research Time 2:00 pm to 4:00 pm Room: Baker 1. Probabilistic consistency transformation for multiple alignment of biological networks Sayed Mohammad Ebrahim Sahraeian, Byung-Jun Yoon Department of Electrical & Computer EngineeringTexas A&M University, College Station, TX 77843-3128, USA. 2. Attractor Estimation and Model Refinement for Stochastic Regulatory Network Models Jason Knight1, Edward Dougherty1, 2 1. Dept. of Electrical and Computer Engineering, Texas A&M University College Station, Texas 77843 USA 2. Computational Biology Division, Translational Genomics Research Institute,Phoenix, Arizona 85004 USA. 3. Steady state probability approximation applied to stochastic model of biological network Md. Shahriar Karim, David M. Umulis and Gregery T. Buzzard. 4. Identification of biomarkers in breast cancer metastasis by integrating protein-protein interaction network and gene expression data Md Jamiul Jahid, Jianhua Ruan Department of Computer Science The University of Texas at San AntonioSan Antonio, USA 5. Pathway Analysis in the Context of Bayesian Networks - Mathematical Modeling of Master and Canalizing GenesChen Zhao1,2, Ivan Ivanov3, Michael L. Bittner2, Edward R.Dougherty1, 2, 4 1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA. 2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA. 3.Dept. of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA. 4.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. 6. Gene Network Inference via Sparse Structural Equation Modeling with Genetic Perturbations Xiaodong Cai1, Juan Andr´es Bazerque2, Georgios B. Giannakis2. 1.Dept. of ECE, Univ. of MiamiCoral Gables, FL 33146, USA. 2.Dept. of ECE, Univ. of Minnesota, Minneapolis, MN 55455, USA. 4:00 pm to 4:20 pm Session: 5 Break & posters Data Integration Chair: Dr. Xiaoning Qian, University of South Florida Time 4:20 pm to 6:20 pm Room: Alamo 1. Improvement of GNs inference through biological data integration F´abio Fernandes da Rocha Vicente1;2, Fabr´ıcio M. Lopes1, Ronaldo F. Hashimoto2 1. Federal University of Technology - Paran´a, Brazil 2. Institute of Mathematics and Statistics, University of S˜ao Paulo, Brazil 2. Multisource Biological Pathway Consolidation Mark S. Doderer1, Zachry Anguiano1, Uthra Suresh1, Ravi Dashnamoorthy1, Alexander J.R. Bishop1, 2, 4, and Yidong Chen1, 3, 4 1.Greehey Children’s Cancer Research Institute. 2.Department of Cellular and Structural Biology. 3. Department of Epidemiology and Biostatistics, and 4.Cancer Therapy & Research Center, The University of Texas Health Science Center at San Antonio San Antonio, USA. 3. A Method For Finding Novel Associations Between Genome-Wide Copy Number And DNA Methylation Patterns Man-Hung Eric Tang1, Vinay Varadan2, Sid Kamalakaran2, Michael Q. Zhang3 ,Nevenka Dimitrova2, James Hicks1 1. Cold Spring Harbor Laboratory, 1 Bungtown Rd, NY 12724, USA 2. Philips Research North America, 345 Scarborough Rd, Briarcliff Manor, NY 10510, USA 3. The University of Texas at Dallas, Richardson TX 75080, USA and Tsinghua University, Beijing, 100084 China. 4. Stochastic Modeling of Dynamic Effects of Copy Number Alterations upon Gene Expression Levels Fang-Han Hsu1, Erchin Serpedin1, Yidong Chen2,3, and Edward R. Dougherty1, 4 1. Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX. 2. Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, TX. 3. Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX. 4. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ. 5. Efficient Cancer Therapy using Boolean Networks and Max-SAT-based ATPG Pey-Chang Kent Lin, Sunil P. Khatri Department of ECE, Texas A&M University, College Station TX 77843 6. Designing Enhanced Classifiers Using Prior Process Knowledge: Regularized Maximum-Likelihood Mohammad Shahrokh Esfahani1, Amin Zollanvari2, Byung-Jun Yoon1, and Edward R. Dougherty1,3 1.Department of Electrical and Computer Engineering, Texas A&M University. 2. Childrens Hospital Informatics Program at Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Brigham and Womens Hospital. 3. Computational Biology Division, Translational Genomics Research Institute (TGen), Phoenix, Arizona, USA. Session: 6 Proteomics data processing Chairs: Dr. Ulisses Braga-Neto, Texas A&M University Dr. Jianqiu (Michelle) Zhang, University of Texas at San Antonio Time 4:20 pm to 6:20 pm Room: Baker 1. Finding Effective Subnetwork Markers for Cancer by Passing Messages Byung-Jun Yoon Department of Electrical and Computer Engineering Texas A&M University, College Station, TX. 2. Application of Survival Analysis Methodology to the Quantitative Analysis of LC-MS Proteomics Data Carmen D. Tekwe, Alan R. Dabney, Raymond J. Carroll Department of Statistics Texas A & M University College Station, TX 77843-3143 3. Mapping of International Protein Index to Affymetrix Probe-Set Identifier for Correlating Genomics and Proteomics Expression Profiles in Multiple Myeloma Shweta S. Chavan 1,2, John D. Shaughnessy Jr.1, Bart Barlogie1, Ricky D. Edmondson1 1.Myeloma Institute for Research and Therapy, University of Arkansas Medical Sciences (UAMS), 4301 W. Markham Street, Slot#776, Little Rock, AR 72205, USA. 2. University of Arkansas Little Rock–UAMS Joint Bioinformatics Program, 2801 S. University Avenue, Little Rock, AR 72204, USA. 4. Multiple Reaction Monitoring: Modeling and Systematic Analysis Esmaeil Atashpaz-Gargari1, Ulisses M. Braga-Neto1, and Edward R. Dougherty1;2;3 1. Dept. of Electrical and Computer Engineering, Texas A&M University. 2. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ. 3. Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX. 5. Joint Corresponding Feature Identification and Alignment for Multiple LC/MS Replicates Jian Cui, Xuepo Ma, Jianqiu(Michelle) Zhang Department of Electrical and Computer Engineering University of Texas at san Antonio San Antonio, Texas 78249. 6. Modeling and systematic analysis of LC-MS proteomics pipeline Youting Sun1, Ulisses Braga-Neto1, Edward R. Dougherty1;2;3 1. Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX. 2. Computational Biology Division, Translational Genomics Research Institution, Phoenix, AZ. 3. Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX Session: 7 Next Generation Sequencing Data analysis and Application Chair: Dr. Yidong Chen, University of Texas Health Science Center at San Antonio Time 4:20 pm to 6:00 pm Room: Mahncke 1. Enabling Atlas2 Personal Genome Analysis on the Cloud Uday S. Evani1,4, Danny Challis1, Jin Yu1, Andrew R. Jackson2,3, Sameer Paithankar2,3, Matthew N. Bainbridge1, Cristian Coar-fa2,3, Aleksandar Milosavljevic2,3,4, Fuli Yu1,3,4 1. The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. 2.Bioinformatics Research Laboratory, Epigenome Center, Department of Molecular and Human Genetics. 3. Department of Molecular and Human Genetics, Baylor College of Medicine, TX 77030, USA. 4. Corresponding authors. 2. A Sequential Monte Carlo Base-calling Method for next-generation DNA Sequencing XiaohuShen and HarisVikalo Department of Electrical and Computer Engineering, University of Texas at Austin 3. Comparative Copy Number Variation from Whole Genome Sequencing Angel Janevski, VinayVaradan, SitharthanKamalakaran, Nilanjana Banerjee, Nevenka Dimitrova Philips Research, 345 Scarborough Rd, Briarcliff Manor, NY 10510. 4. Beyond Seed Match: Improving miRNA Target Prediction using PAR-CLIP Data Mingzhu Lu1, C. L. Philip Chen2, Yufie Huang1 1. Department of Electrical and Computer Engineering, The University of Texas at San Antonio, TX, USA. 2. Faculty of Science of Technology, University of Macau, China. 5. Put your NGS data to work: Creating Biological Contextualization with Agilent’s Next-Gen Sequencing Analysis Software Dipanwita Roy Choudhury Agilent 7:00 pm to 9:00 pm Banquet at Mi Tierra December 6, 2011 Plenary Talks Room: Alamo 8:00 am to 8:45 am Plenary talk 4 Chair: Dr. Fuli Yu Selectionism vs. neutralism in the evolution of cells of hepatocelluar carcinoma Dr. Chung-I Wu Professor and Director, Beijing Institute of Genomics, Chinese Academy of Science. Department of Ecology and Evolution University of Chicago 8:45 am to 9:30 am Plenary talk 5 Chair: Dr. Yufei Huang Systems Pharmacology Strategies for Faster-to-Market Drug Development Dr. Stephen Wong Senior Member, The Methodist Hospital Research Institute, Department Chair, John S Dunn, Distinguished Endowed Chair in Biomedical Engineering, Department of Systems Medicine and Bioengineering , Associate Director of Translational Research, Methodist Cancer Center, Professor of Radiology, Professor of Neuroscience, Professor of Pathology and Laboratory Medicine,Weill Cornell Medical College of Cornell University 9:30 am to 9:50 am Break & posters Main Sessions Session: 8 Clustering and Classification Methods Chair: Dr. Ranadip Pal, Texas Tech University Time 9:50 am to 11:50 am Room: Alamo 1. Classifier Error Estimator Performance in a Bayesian Context Lori Dalton1, Edward R. Dougherty1, 2, 3 1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX USA. 2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ USA. 3.Dept. of Bioinf. and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX USA. 2. Sample-Based Estimators for the Intrinsically Multivariate Prediction Score Ting Chen, Ulisses Braga-Neto Department of Electrical Engineering Texas A & M University College Station, Texas 77843 3. Clustering Gene Expression Data using Probabilistic Non-negative Matrix Factorization Belhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering Ecole Nationale d’Ing´enieurs de Tunis, Tunisia. 2. Department of Systems Engineering University of Arkansas at Little Rock, USA. 3. Department of Mathematics University of Alabamaat Birmingham, USA. 4. Relationship between the accuracy of classifier error estimation and distribution complexity Esmaeil Atashpaz-Gargari1, Chao Sima2, Ulisses M. Braga-Neto1, and Edward R. Dougherty1, 2, 3 1. Dept. of Electrical and Computer Engineering, Texas A&M University. 2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ. 3.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX. 5. Geometrical Modification Of Wavelet SVM Kernels And Its Application In Microarray Analysis Hong Cai , Yufeng Wang Department of BiologyUniversity of Texas at San Antonio, San Antonio, TX 78249, USA. 6. S-score : a Novel Scoring Method of Gene Signatures for Molecular Classification Hung-I Harry Chen1, Tzu-Hung Hsiao1, Yidong Chen1, 2, Charles Keller3 1.Greehey Children’s Cancer Research Institute 2.Department of Epidemiology and Biostatistics,University of Texas Health Science Center at San Antonio, San Antonio, Texas 3. Pediatric Cancer Biology Program, Pap Papé Family Pediatric Research Institute Family Pediatric Research Institute,Department of Pediatrics, Oregon Health and Science University, Portland, Oregon. Session: 9 MicroRNA, Gene Networks, Next-Generation Sequencing Methods Chair: Dr. Byung-Jun Yoon , Texas A&M University Time 9:50 am to 11:50 am Room: Baker 1. Computational Prediction of microRNA Regulatory Pathways Dong Yue1, Yidong Chen2, Shou-Jiang Gao3, Yufei Huang1 1.Department of Electrical and Computer Engineering, University of Texas at San Antonio, U.S. 2.Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, U.S. 3. Departments of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, U.S. 2. Inference of a Genetic Regulatory Network model from limited time series data SaadHaider,Ranadip Pal Texas Tech University, Lubbock, TX, 79409, USA. 3. Modelling Oxidative Stress Response Pathways Sriram Sridharan1, Ritwik Layek1, Aniruddha Datta1, Jijayanagaram Venkatraj2 1. Texas A & M University, Electrical and Computer Engineering, College Station, TX, 77843-3128, USA. 2. Texas A & M University, Vet Integrative Biosciences, College Station, TX, 77843-4458, USA. 4. Clustering DNA methylation expressions using nonparametric beta mixture model Lin Zhang1, Jia Meng2, Hui Liu1, Yufei Huang1 1.School of Information and Electrical Engineering, China University of Mining and Technology 2. Department of Electrical and Computer Engineering, University of Texas at San Antonio, U.S. 5. A Novel Approach for Alignments Output Storage Problem Facing Clinical Scenarios Yiqi Lu1,Yaoliang Chen2, Fuli Yu3,Yanghua Xiao4,Danfeng Xu5 1. School of Computer Science, Fudan University Shanghai 200433, PR China. 2. School of Computer Science, Fudan University Shanghai 200433, PR China. 3. The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030 USA. 4. School of Computer Science, Fudan University Shanghai 200433, PR China. (Corresponding Author) 5. School of Computer Science, Fudan University Shanghai 200433, PR China. 6. Personal Genome Privacy Protection with Feature-based Hierarchical Dual-stage Encryptions Xukai Zou1, Peng Liu2, Jake Y. Chen3 1. Department of Computer & Information Science,Purdue University Indianapolis, IN 46202, USA. 2. College of Information Science and Technology Penn State University, University Park, PA 16802, USA. 3. School of Informatics Indiana University Indianapolis, IN 46202, USA. Session: 10 ISIMB 2011 Chairs: Dr. Yufang Jin, Universityof Texas at San Antoni Time 9:50 am to 11:50 am Room: Mahncke 1. ECF sigma factor-associated regulatory networks in Streptomyces colicolor A3(2) Zhan Zhou1, 2, Qi Li1, Julie Tudyk1, Yong-Quan Li2 and Yufeng Wang1, 3 1. Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA. 2. College of Life Sciences, Zhejiang University, Hangzhou 310058, P. R. China. 3. South Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, San Antonio, TX 78249, USA. 2. Transcriptomic analysis using svd clustering and svm classification Hong Cai , Yufeng Wang Department of BiologyUniversity of Texas at San Antonio, San Antonio, TX 78249, USA 3. A Compton scattering suppression based Image reconstruction method for digital brest tomosynthesis Shiyu Xu1 and Ying Chen1,2 1. Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901. 2. Biomedical Engineering Graduate Program,Southern Illinois University. 4. Effects of slice thickness filter in filtered backprojection reconstruction with parallel breast tomosynthesis imaging configuration Linlin Cong1, Weihua Zhou2, Ying Chen1,2 1. Biomedical Engineering Graduate Program,Southern Illinois University. 2. Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901. 5. Targeting myocardial infarction-specific protein interactions using computational analyses Nguyen Nguyen1, Xiaolin Zhang1,Yunji Wang1, Hai-Chao Han1, Yufang Jin1, Galen Schmidt2, Richard A. Lange3, Robert J. Chilton3, Merry Lindsey3 1. Dept. of ECE University of Texas at San Antonio San Antonio, TX 78249, USA. 2. Dept. of ECE Rice University Houston, TX 77005, USA. 3. Dept. of Medicine University of Texas Health Science Center at San Antonio San Antonio, TX 78229, USA. 6. Mathematical modeling of macrophage activation in left ventricular remodeling post-myocardial infarction Yunji Wang1, Yufang Jin1, Yonggang Ma2, Ganesh V Halade2, Merry L. Linsey2 1.Department of Electrical and Computer Engineering, University of Texas at San Antonio San Antonio, Texas 78249, USA. 2. Department of Medicine-Cardiology University of Texas Health Science Center at San Antonio San Antonio, TX 78229, USA 1:30 pm to 5:30 pm Hands-on workshop on next Gen-sequencing Data Analysis UTSA Downtown Campus Buena Vista St. Bldg 3.328 By Texas Advanced Computing Center