Module Specification An online version of this specification is available to prospective students at http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section3_moduledescript/in dex.html GENERAL INFORMATION Module name Molecular Cell Biology & Infection Module code 3260 Module Organiser Dr Theresa Ward Contact email Theresa.Ward@lshtm.ac.uk Home Faculty Faculty of Infectious & Tropical Diseases Level This module is at Level 7 (postgraduate Masters ‘M’ level) of the QAA Framework for Higher Education Qualifications in England, Wales & Northern Ireland (FHEQ). Credit LSHTM award 15 credits on successful completion of this module. Accreditation Not currently accredited by any other body. Keywords Host-pathogen interactions; intracellular pathogens; bacterial infections; innate immunity; cell biology; membrane trafficking; cytoskeleton; microscopy. AIMS, OBJECTIVES AND AUDIENCE Overall aim To provide students with an understanding of the key aspects of the cell biology of mammalian cells, particularly cells of the immune system, and how this relates to the establishment and survival of intracellular microorganisms. Intended learning outcomes By the end of this module, students should be able to: Target audience Evaluate the diversity of host cell-pathogen interactions; Demonstrate an understanding of the cytoskeleton and cellular events it regulates; Distinguish the triggers and mechanisms of endocytosis / phagocytosis and of the secretory pathway; Describe the molecular signals governing cell cycle control; Compare how various microbes utilise, distort, subvert, or are influenced by the host cell biology during infection, either by the host cell cycle or by membrane trafficking; Critically assess and analyse the methodology for studying molecular cell biology and infection. This module is intended for students wishing to focus in depth on the cell biology of the host-pathogen relationship, and those wishing to gain further insight into general mammalian cell biology. 1 CONTENT Session content The module is expected to include sessions addressing the following topics in the context of cells with and without pathogens (though please note that these may be subject to change): Cell cycle control ; Endocytosis, phagocytosis and vacuoles; Exocytosis and cytoskeleton; Trypanosomes and cell survival mechanisms; Light and electron microscopy; Ethics of data analysis and presentation. TEACHING, LEARNING AND ASSESSMENT Study resources provided or required Lecture handouts will be provided. Teaching and learning methods Primarily by lectures, for introductory material, and by structured discussion involving student presentations. Assessment details Assessment will be a short answer test at the end of the module based on data analysis and material covered in lectures and presentations. (100% 1.5 hours) For students who are required to re-sit, or granted a deferral or new attempt, the task will be a short answer test based on data analysis and material covered in lectures and presentations. (100% 1.5 hours) Assessment dates Assessments will take place on 20 May 2016. For students who are required to re-sit, or granted a deferral or new attempt, the next assessment date will be the School-recommended date in mid/late September 2016. Language of study and assessment English (please see ‘English language requirements’ below regarding the standard required for entry). TIMING AND MODE OF STUDY Duration The module runs for 5 weeks at 2.5 days per week; this module runs between Wednesday morning and Friday lunchtime. Dates For 2015-16, the module will start on Wednesday 20 April 2016 and finish on Friday 20 May 2016. Timetable slot The module runs in LSHTM timetable slot E. Mode of Study The module is taught face-to-face in London. Both full-time and part-time students follow the same schedule. For full-time students, other LSHTM modules are available in the other half of the week for the C and D slots. Learning time The notional learning time for the module totals 150 hours, consisting of: Contact time ≈ 32 hours Directed self-study ≈ 32 hours Self-directed learning ≈ 41 hours Assessment, review and revision ≈ 45 hours 2 APPLICATION, ADMISSION AND FEES Pre-requisites A basic understanding of cell biology is required. English language requirements A strong command of the English language is necessary to benefit from studying the module. Applicants whose first language is not English or whose prior university studies have not been conducted wholly in English must fulfil LSHTM’s English language requirements, with an acceptable score in an approved test taken in the two years prior to entry. Applicants may be asked to take a test even if the standard conditions have been met. Student numbers Student numbers are typically 10-20 per year; numbers may be capped due to limitations in facilities or staffing. Student selection Preference will be given to LSHTM MSc students and LSHTM research degree students. Other applicants meeting the entry criteria will usually be offered a place in the order applications are received, until any cap on numbers is reached. Applicants may be placed on a waiting list and given priority the next time the module is run. Full Registration (full participation) by LSHTM research degree students is required for this module, although the assessment for research degrees students is optional. Fees For registered LSHTM MSc students, fees for the module are included within MSc fees (given on individual course prospectus pages). If registering specifically for this module, as a stand-alone short course, individual module fees will apply. Tuition fees must be paid in full before commencing the module, or by any fee deadline set by the Registry. Scholarships Scholarships are not available for individual modules. Some potential sources of funding are detailed on the LSHTM website. Admission deadlines For 2015-16: For registered LSHTM MSc students, the module choice deadline (for Term 2 and 3 modules) is Friday 20 November 2015. If registering specifically for this module, applications should be submitted at least 8 weeks prior to the start of the module. Formal registration will take place on the morning of the first day of the module. ABOUT THIS DOCUMENT This module specification applies for the academic year 2015-16 Last revised 4 July 2014 by Theresa Ward; Minor amendments 20 July 15 SDB London School of Hygiene & Tropical Medicine, Keppel St., London WC1E 7HT. www.lshtm.ac.uk 3