Request for Proposals Request for Proposals: Cooperative Research Partnership Grants Overview The purpose of the Cooperative Research Partnership Grants is to fund collaborative nursing research projects jointly facilitated by The Queen’s Medical Center, Queen Emma Nursing Institute (QMC-QENI) and the University of Hawai’i School of Nursing and Dental Hygiene (UHM-SONDH) that support collaborative development of nursing science and translational research in clinical practice and health policy for the period: July 1, 2014 to June 30, 2017. Maximum amount awarded per proposal: $25,000 across three years, with the third year allotted for dissemination only Anticipated number of awards: 2-3 per year Eligible organizations: QMC-QENI in partnership with UHM-SONDH Eligible QMC-QENI Principal Investigators: Full time QMC nurses with a minimum of a BS in nursing. Eligible UHM-SONDH Principal Investigators: Priority is to full time junior tenure-leading faculty who are not prior recipients Eligible Co-PIs: A QMC PI who is a classified student progressing towards a graduate degree at SONDH may use this partnership to complete a thesis or dissertation with the advisor’s approval. In this case, the UH Co-PI must serve as the advisory, chair, or committee member. Introduction The Queen Emma Nursing Institute (QENI) as part of Queen’s Medical Center (QMC) in collaboration with the School of Nursing and Dental Hygiene (SONDH) seeks to fund research conducted by nurses and university faculty working in teams. Research may include descriptive, qualitative, or experimental studies. Research Goals and Objectives The objective of this RFP is to support scientifically sound research related to the Queen’s priority areas of patient safety, patient outcomes, and/or work environment. Priority will be given to projects that align with the organizational and/or nursing strategic goals for each fiscal year. The purpose is two-fold: 1) QENI: To provide research support and mentoring opportunities to QMC nurses interested in research in QMC’s priority areas. Projects with potential to build nursing practice excellence at The Queen’s Medical Center will receive priority for funding. 1 of 10 Request for Proposals 2) UHSONDH: To provide a mechanism for faculty experience in grant writing, developing their program of research, and enhancing clinical acumen in support of QMC priority areas. Partnership 1) This initiative will be operated jointly through a QENI and SONDH Research Collaborative with representatives from both organizations. 2) Administrative support for grant administration will be the responsibility of both institutions. Program administration will be under the auspices of the QENI for all QMC related costs and the Office of Research and Extramural Programming (OREP) at SONDH for all SONDH related costs . 3) The targeted outcome of this initiative is to encourage the development of partnerships between researchers from QMC and SONDH. As such, a Principal Investigator will be identified from both QMC and SONDH. Together, these two investigators will function as Co-PI’s collaborating on conceptual development, proposal submission, conduct of the project, data analysis, and submission of results for presentations and development of manuscripts. Additional investigators may be included as relevant to the area of inquiry. 4) The SONDH will provide statistical and editorial assistance. 5) QMC staff and SONDH will jointly own the intellectual knowledge of the research project including data, analysis, presentations, and manuscripts. Approval must be obtained by both Principal Investigators to disseminate and utilize knowledge gained during the research partnership. Key Annual Dates Release Date: October 21 Letters of Intent Receipt Date(s): November 30 Application Receipt Date: March 31 Notification Date: May 15 Earliest Anticipated Start Date: July 1 Content and Form of Application Requirements (see Attachment A) Application Review Information Review and Selection Process Applications that are complete and responsive to the RFP will be evaluated for scientific and technical merit by a peer review group convened by the QENI and SONDH. As part of the initial merit review, all applications will: Undergo a selection process in which applications will be discussed and assigned a priority score. 2 of 10 Request for Proposals Receive the written peer review and have the opportunity to discuss the review with the Directors of QENI and OREP. Each of the criteria below will be addressed and considered in reviewing the application. Note that an application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, an investigator may propose to carry out important work that by its nature is not innovative but is essential to move the field forward. Significance: Does this study address an important problem? If the aims of the application are achieved, how will scientific knowledge or clinical practice be advanced? What will be the potential effect of these studies on the concepts, methods of research and/or practice? What is the impact on patient/nurse outcomes? What are the technologies, treatments, services, or preventative interventions that drive this field? Translation to Practice: How will the results of this study be used to improve nursing practice? How will results be disseminated to nurses in a timely fashion? How will the researchers promote practice change based on the findings of the research? Is the plan for practice change appropriate to the projected project benefit? Approach: Are the conceptual or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? Is the likelihood of successful project completion high given the current state of research and development and the stated technical approach? Are the proposed timeline and interim milestones appropriate, feasible and technically sound? Investigators: Are the investigators appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the principal investigator and other researchers? Does the investigative team bring complementary and integrated expertise to the project (if applicable)? Milestones and Product Development Plan: Are the defined objectives/milestones and future product development plans appropriate and feasible? Additional Review Criteria: In addition to the above criteria, the following items will continue to be considered in the determination of scientific merit and the priority score: Protection of Human Subjects from Research Risk: The involvement of human subjects and protections from research risk relating to their participation in the proposed research will be assessed. IRB approval is required from both QMC and UH boards. 3 of 10 Request for Proposals Budget: The reasonableness of the proposed budget and the requested period of support in relation to the proposed research. The priority score should not be affected by the evaluation of the budget. Award Administration Information Award Notices After the peer review of the application is completed, the Co-PIs will be notified on or before May 15. Co-Principal Investigator Responsibilities The Co-Principal Investigators will have the primary responsibility for defining the research objectives, approaches, and details of the projects and for performing the scientific activity within the guidelines of the RFP. Specifically, Co-PI awardees agree to accept mutual responsibility for the coordination, cooperation, and participation for the management of the project (see Attachment B). The Co-Principal Investigators will be responsible for providing status reports to the Partnership Steering Committee on a monthly basis via email (see Attachment C). Since the funding for each project comes from QENI and the SONDH, it is advised that the Co-PIs work with the Director of QENI and/or Director of Research at SONDH to delineate the funding source for each item. The budget should be developed using the Excel spreadsheet in Attachment D. Presentation Awardees will be required to present their studies at the annual research conference held in Hawaii, the Pacific Institute of Nursing. Other presentations are encouraged. Publication in a peer-reviewed journal is expected. 4 of 10 Request for Proposals Attachment A. Application Requirements The application should be prepared in using Arial font with a minimum font size of 11. The document should be single-spaced. Use at least one-half inch margins (top, bottom, left & right) for all pages. Please add the PI’s name to the header and the page number to the footer on each page. No information should appear in the margins. Headings and sub-headings for the document must include the following: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 5 of 10 Abstract: A concise overview of the proposed study (no more than 1 page) Previous Research Experience Research Plan (maximum 20 pages) a. Specific Aims b. Background & Significance c. Theoretical Framework d. Methods 1) Design 2) Sample, include exclusion/inclusion criteria, and sample size calculation 3) Recruitment/retention strategies 4) Tools, materials required 5) Procedure with milestones and timeline 6) Data Analysis 7) Possible limitations Translation to Practice a. Describe how the results of this study will be used to improve nursing practice. Describe how the results will be disseminated to nurses in a timely fashion. b. Describe how the researchers will promote practice change based on the findings of the research? Dissemination Plan a. Identify local and/or national conference for presentation b. Identify journal for publication Protection of Human Subjects a. IRB approval must be obtained from the QMC Institutional Review Board followed by a request to UH IRB to cede authority to QMC (see Attachment E for template) b. Approval from both institutions must be obtained prior to the commencement of the study. Reference List Budget and Justification (see Attachment D) a. Personnel 1) Salary for 11-mos or 9-mos appt plus overload, if applicable 2) Fringe benefits b. Consultant Costs (if any) c. Supplies are items < $5000 each; Equipment is for items > $5000 d. Travel Costs e. Other Expenses f. Budget Justification Biographical sketch for each team member (4-page maximum limit) (see Attachment E). A biographical sketch format page and sample for NIH PHS 398 form can be found at: http://grants1.nih.gov/grants/funding/phs398/phs398.html. Signed Co-Principal Investigator Responsibilities (see Attachment B) Request for Proposals Attachment B. Co-Principal Investigator Responsibilities The purpose of this Partner Agreement Form is to outline the expectations of partnering Co-Principal Investigators participating in the Cooperative Research Partnership between the School of Nursing and Dental Hygiene and the Queen’s Medical Center. The Cooperative Research Partnership supports scientifically sound research related to any of the clinical areas represented by the services lines of Queen’s Medical Center in the priority areas of patient safety, patient outcomes and/or work environment. Guiding Principle The partnership will be a collaborative and equitable research partnership where members draw upon individual skill sets to mutually meet the goals of the project Roles and Responsibilities of Project Team Members The Cooperative Research Partnership recognizes that roles and responsibilities may differ among partnering investigators as each partner brings expert knowledge of their work setting. However, it is expected that both partners will serve as Co-Principal Investigators sharing equally in project activities as described below. Please read, sign, and submit the following agreement with your proposal. As Co-Principal Investigator, I agree to: 1. Share responsibilities of proposal writing and grant management, inclusive of fiscal monitoring, personnel hiring, IRB approval, recruitment of subjects, data management, and report writing with my Co-PI. 2. Work with my Co-PI as an active team member. 3. Respect the expertise of my Co-PI while concurrently identifying strengths and weaknesses of the partners and partnership in order to identify gaps and need for outside help. 4. Communicate with my Co-PI a minimum of twice a month. 5. Ensure that all research involving human subjects and revisions are submitted to QMC Institutional Review Board (IRB) within 3 months of the award and approved by both the QMC IRB and UH IRB prior to data collection. In the event that either IRB requests revisions, these revisions must be reviewed by the Director, Queen Emma Nursing Institute and the UH Partnership Director prior to re-submission to the respective IRB. 6. Secure all research records, consent documents, and source documents for at least three years past completion of the research activity. 7. Disseminate findings of the research activity within six months of the completed final report. 8. Attend monthly team meetings and be prepared to provide a verbal status report. 9. Submit quarterly verbal In Progress Review Reports to the Director of Queen Emma Nursing Institute and the Director of Research at UH. ____________________________ Signature Typed Name: Co-Principal Investigator Queen’s Medical Center 6 of 10 ___________________________ Signature Typed Name: Co-Principal Investigator University of Hawaii SONDH Request for Proposals Attachment C. Status Report STUDY TITLES 7 of 10 DATE FUNDED Comedy in Chemotherapy 2007 Alternative Teaching Strategy for the Renal Clients Undergoing Hemodialysis 2007 Nurse-Delivered Smoking Cessation Intervention in an Acute Care Setting 2007 Effects of Disposable Underpads on Pressure Ulcer Prevention 2007 Enhancement of ED Staff Ability, Willingness and Readiness for Disaster Duty 2007 Screening and Prevention of Contrast-Induced Nephropathy 2008 Nursing Management of Fever in Patients with Traumatic Brain Injury 2008 Coping Mechanisms of Pregnant Adolescents and Their Parents 2009 Developing the Emotional Intelligence of clinical oncology nurses 2009 Providing A ‘Good Death’: Emergency Department Nurses’ Interventions for Improving End-of-Life Care 2010 The Efficacy of Written and Verbal Pelvic Floor Exercise Discharge Instructions in Reducing Urinary Incontinence among Postpartum Patients 2010 Spousal Deployment During Pregnancy: The Impact on Medical Utilization and Obstetrical Outcomes 2010 The Feasibility of a Nurse Managed Transition Clinic for Patients with a Diagnosis of Diabetes Recently Discharged from the Hospital 2011 Patterns of Retention and Turnover among Registered Nurses 2011 Parent’s and Children’s Perceptions of Type 1 Diabetes: Health-Related Quality of Life and Impact on Family 2011 CLINICAL SITE IRB APPROVED Study Discontinued Study Discontinued UH IRB APPROVED DATA COLLECTION DATA ANALYSIS DISSEMINATION TRANSLATION TO PRACTICE Request for Proposals Attachment D. Budget & Justification (On separate pages in narrative form for each purchase) Proposal Title: Principal Investigator: BUDGET QMC UH YEAR ONE Cost: Cost: Personnel: BUDGET QMC UH YEAR TWO Cost: Cost: Personnel: Co-PI (QMC) (@ 8 hrs per mo.) Co-PI (UH) (@ 8 hrs per mo) Co-PI (QMC) (@ 8 hrs per mo.) Co-PI (UH) (@ 8 hrs per mo) Statistician (10 hrs @ $50/hr) Research Asst (QMC) (30 hrs @ $20/hr) Registered Nurse (100 hrs @ $40/hr) Supplies: Supplies: Notebook laptop Software for laptop Media costs Participant incentives Travel: Media costs Participant incentives Travel: Parking fees (QMC & UH) TOTAL REQUEST: 8 of 10 Mainland conference-(x 2 PIs) Mainland conferenceLocal conference-PIN (x2 PIs) Parking fees (QMC & UH) TOTAL REQUEST: Request for Proposals Attachment E. Template Request to Cede IRB Authority TO: Chair, Biomedical IRB OR Chair, Social and Behavioral Sciences IRB Committee on Human Studies University of Hawaii FROM: Faculty Name & Title DATE: XX Month XXXX RE: Request to Cede Human Subjects Review and Oversight 1. As the Co-Principle Investigator for the study entitled, “TITLE”, I am requesting the UH IRB cede authority to provide human subjects review, approval, and oversight to the Queen’s Medical Center (QMC) IRB. 2. The UH School of Nursing & Dental Hygiene (SONDH) has established Research Partnerships with the Queen’s Medical Center (QMC) and Tripler Army Medical Center (TAMC). Under this partnership, a faculty investigator from the SONDH is paired with a nurse clinician investigator from one of the two clinical sites (QMC or TAMC). These Co-Principle Investigators respond to an annual Request for Proposals and develop a clinically-relevant research protocol, undergo a blinded review, and receive seed funding from both institutions to conduct their two - to three-year study at the appropriate clinical site. In the past, these studies have been submitted for IRB approval from the clinical site and from the UH IRB. Under the oversight of the Partnership Directors, Drs. Debra Mark, SONDH and Rene’e Latimer, QMC, each project is reviewed monthly for budget, IRB approvals, and progress. SONDH contributes the Partnership Director’s time, who is responsible for coordinating the Partnership and providing statistical consultation and funding that is matched by the clinical site 3. For this study, QMC will be the exclusive site for the conduct of the study and the recruitment of subjects. The UH faculty Co-Principal Investigator will participate in the study by performing the following activities: XXX, XXX, and XXX. 4. I have submitted an application to the QMC IRB (see Attachment 1), reviewed under exempt, expedited, OR full review, and received their approval (see Attachment 2); the study was deemed to be minimal risk (as applicable). The protocol has also been reviewed by QMC’s ethical/legal/etc. department (as applicable). 5. If you have any questions, please contact me at XXX-XXXX or via email at xxxxx@hawaii.edu. 9 of 10 Request for Proposals Attachment F. Biosketch Program Director/Principal Investigator (Last, First, Middle): BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES. NAME POSITION TITLE eRA COMMONS USER NAME (credential, e.g., agency login) EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) DEGREE INSTITUTION AND LOCATION YEAR(s) FIELD OF STUDY (if applicable) A. Positions and Honors. List in chronological order previous positions, concluding with your present position. List any honors. Include present membership on any Federal Government public advisory committee. B. Selected peer-reviewed publications (in chronological order). Do not include publications submitted or in preparation. For publicly available citations, URLs or PMC submission identification numbers may accompany the full reference; copies of publicly available publications are not accepted as appendix material. C. Research Support. List selected ongoing or completed (during the last three years) research projects (federal and non-federal support). Begin with the projects that are most relevant to the research proposed in this application. Briefly indicate the overall goals of the projects and your role (e.g. PI, Co-Investigator, Consultant) in the research project. Do not list award amounts or percent effort in projects. 10 of 10