Introduction The development of the neoprene survival suit has greatly benefited individuals exposed to environments where cold water immersion is a health and safety concern. Neoprene is a very good insulator due to its low thermal conductivity, which lessens the transfer of heat through the material. When used as survival suits for ship wreck situations where hypothermia is a concern, neoprene suits can greatly extend survival time for an individual. In ship wreck situations it is particularly important to know the amount of time an individual has to survive. Predicting the extension of survival time that these suits provide is advantageous for both specifying the type of suit required for safety in certain situations as well as in the aid of search and rescue teams. By knowing beforehand how long a victim has to survive, search and rescue teams are better able to coordinate their missions. For individuals adrift at sea in cold water the primary cause of death is hypothermia. Hypothermia occurs when the body’s core temperature drops to a level where normal muscular and cerebral functions are impaired. It is generally accepted that the core temperature at which hyperthermia becomes fatal is 30 degrees Celsius. At this temperature, the body is incapable of producing enough heat to counteract heat loss, and the result is death. By providing added insulation, survival suits limit heat loss from the body, greatly slowing the drop of core temperature. Determining survival time then is based on the body core temperature drop. Many analytical and finite element models have been proposed that simulate the core temperature drop, allowing predictions of survival time to be made. Early models by Gagge et al[8] used analytical methods and a single cylinder human analog to predict survival time. Tikuisis, Tarlochan, and Fanger all used single cylinder models. More advanced models use a segmented multi-cylinder approach, such as Ferreira et al. In these studies, survival time was predicted by observing core body temperature change for certain cases of water temperature and biophysical parameters of the survivor. Design Objectives By creating a simplified model of a human in Comsol multiphysics, a finite element based software program, we plan to simulate core body temperature as a function of time to determine survival time. We can then examine the relationship between wetsuit thickness and survival time by varying the wetsuit thickness in our model. The criteria for determining survival time will be taken as the point at which the core body region drops to a temperature of 30 degrees Celsius[1]. The human will be modeled as a single cylinder with the cylinder being divided into corresponding layers of the core region, muscle, fat, skin, and the wetsuit layer. Body region sizes will correspond to a statistically average adult male. The first part of the study focuses on validating the comsol model by comparing results with other case studies and models. The later part of the study compares results for survival time of different thickness wetsuits. Methodology Governing Equations The basic energy balance used to determine heat loss from the body is, πππ‘π ππ πβππππ ππ πππ‘πππππ ππππππ¦ = βπππ‘ πππππ’πππ − βπππ‘ πππ π‘ ππ ππ‘ = ππππ − ππππ π‘ 1 In equation 1, the work term is not included. This is because it is assumed that the subject is stationary, and therefore not exerting any work. Heat produced (ππππ ) in equation 1 represents basal metabolic rate as well as heat generated from shivering. Basal metabolic rate, or BMR, is essentially the amount of calories that a person burns in a given amount of time. A rough estimate of about 2000 calories per day can be used to start out with, but the research 1|Page that we have seen indicates that a person’s BMR increases when exposed to cold environments [2]. We can expect to see values reaching as high as 250 Watts[2]. Heat lost (ππππ π‘ ) in equation 1 is dependent upon the thermal resistance associated with the various body layers and wetsuit which are depicted in Figure 1. Heat loss is also a function of the temperature of the water, and more specifically the heat transfer coefficient around the human body due to the water. Equation 1 can be rewritten as, πΜπΆπ ππ ππ‘ = (π΅ππ + π»π) − πππππ −ππ€ππ‘ππ π π‘ππ‘ππ [Watts] 2 Where BMR is the basal metabolic rate, HS is heat generated due to shivering, πππππ is the core temperature, ππ€ππ‘ππ is the temperature of the water, and π π‘ππ‘ππ is the total thermal resistivity associated with the layers of body tissue, wetsuit, and water. The value for BMR used in the current model is debatable, as our sources are giving conflicting information as to what this value should be. We have discovered that it is somewhere in the range from 100 Watts to 500 Watts, as there are many factors involved in heat production, such as metabolism, blood perfusion, and shivering. Since equation 2 doesn’t take into account the changing core temperature, to better understand the transient conditions we can refer to the transient conduction equation. πΏπ πΏπ‘ π πΏπ‘π 2 π πΏπ₯ = ππ π + ππ π 3 Material Properties Important material properties here are thermal conductivity, density, and specific heat capacity for each body region as well as the wetsuit layer. Material properties for each body region differ only slightly when comparing sources. All properties used in the model are listed in table 1. These properties are held constant with respect to time, and any variation in these values over time is negligible. Properties and Parameters used in the model k cp ρ BM [W m-1 K-1] [J kg-1 K-1] [kg m-3] [W m-3] Core 0.49 3504 1080 3852 Muscle 0.51 3800 1085 684 Fat 0.21 2300 920 368 Skin 0.47 3680 1085 368 Wetsuit 0.15 1268 1400 0 Blood 3850 1059 0 Table 1. Properties and parameters used in the model. A majority of values were taken from Ferreira[9]. BM is the basal metabolic rate per unit volume. Boundary conditions Figure 1. Quarter cross section of the cylindrical geometry used to simulate a human body. Boundary conditions that pertain to the geometry in figure 1 are as follows. The bottom and left boundaries are thermally insulated. The outer-most wetsuit boundary has a heat transfer coefficient of 136π⁄ 2 as well as an ambient temperature π πΎ corresponding to the water temperature which depends on the conditions being simulated. The heat transfer coefficient corresponds to cold water flow around a human body at a velocity of 0.25 m/s, determined experimentally [4]. All internal boundaries are continuous, allowing heat to flow from the core to the surrounding water. The model incorporates basal metabolic heat production rates for not only the core, but the muscle, fat, and skin regions as well. Basal 2|Page metabolism rates for these regions were taken from Ferreira [9] and can be found in table 1. Geometry and mesh 1279 and went up to 22191 DOF. A free mesh was used in the model. Table 2 summarizes the data from the convergence study. DOF 1279 1534 2168 2556 4501 8427 9939 11813 22191 Figure 2. Free mesh generated for the geometry. The geometry is a quarter cross section of a cylinder. It is important to note that the model is not meant to be an accurate model of the entire human thermoregulatory system. Its primary function is to model heat loss from the human body, as well as predict the subsequent drop in core temperature. The dimensions of the cylinder were chosen according to the average surface area and volume of a adult male. Values for average surface area and volume, as well as the average surface to volume ratio of a human were taken from literature by F. Tarlochan and S. Ramesh as well as papers by T.J. Nuckerton[4][6]. The value for body surface area used is 1.8 m2. Body volume is taken to be 66.4 Liters. Surface to volume ratio is 0.0282 m2/L. Mesh convergence study A mesh convergence study was performed in order to ensure that the mesh was an appropriate size for testing. The parameter that was observed for the study was the average temperature of the muscle region of the model. This temperature was found by observing a domain integration for the region where values of temperature were plotted over the time range that the problem was solved for. The study started with a number of degrees of freedom(DOF) of Average Muscle Temp at 2 hours [C] 23.1449 23.07895 23.0686 23.0588 23.108 23.1449 23.1326 23.0588 23.108 Table 2. Data from the convergence study showing little effect of DOF on average temperature. The results of the convergence study show a trend indicating that the number of degrees of freedom has little effect on the results if chosen above 1279 degrees. None of the data points deviate past one tenth of one degree. For the model, we will be working with temperatures significant to only one decimal place. Therefore, as long as we stay above 1279 degrees of freedom, our results should be in the range of mesh convergence. For all of the simulations, approximately 2500 degrees of freedom were used. Results and Discussion Initial results Initial results were compared with a similar one cylinder model by Tikuisis where survival time was estimated for various water temperatures [1]. The study found that for an average sized male nude subject in zero degree Celsius water, survival time was approximately two hours. These conditions were replicated with our model by removing the wetsuit region to simulate a nude subject and setting the external temperature to zero degrees Celsius. A plot was obtained of the core temperature seen in Figure 3|Page 3. Figure 3. Plot of core temperature at point (0,0) versus time in seconds submerged in zero degree water for a nude subject. The survival time is about 2 hours, as this is the point where the temperature reaches 30 degrees Celsius. In this test, our model agrees well with the model used by Tikuisis, as both models predict a survival time of 2 hours for the conditions given. To further verify the model, the team decided to compare results with a case study. In Thermal Balance and Survival Time Prediction of Man in Cold Water[2], core temperatures for humans in zero degree water were measured experimentally for 21 test subjects. Results from this study are summarized in the following graph. We replicated these conditions in our model and observed the cooling rate, which is seen in figure 5. Figure 5. Core temperature at point (0,0) for a nude subject in zero degree water plotted for a 30 minutes interval for our model. From the results of our model, it appears that there is a drop of about 0.8 degrees Celsius for the 30 minute time span. For the model by Hayward, there was a drop of about 2 degrees Celsius for the 30 minutes span. This works out to be a difference of more than a degree between our results and theirs, and so this comparison is inconclusive. Accuracy check The team chose to compare results with both an analytical model as well as experimental data from a paper by Hayward et al [2]. The analytical model is a steady state thermal resistance model referenced in Incropera and DeWitt [13]. The model uses the following thermal resistance equation. ππ −ππππ π π ln( 2) π ln( 3) π π π1 π2 π ln( 4) π3 π ln( 5) π 1 = 2ππΏπ + 2ππΏπ + 2ππΏπ + 2ππΏπ4 + 2ππ π 1 π 2 5 πΏβ 5 Figure 4. Core temperatures for humans in zero degree water, determined experimentally and plotted for a time range of 30 minutes. Study was conducted by Hayward et al [2]. Here, ππ is the core temperature which is set constant at 35 degrees Celsius. ππππ is the water temperature, πΏ is the total length of the cylinder, and π values are thermal conductivity values for the different layers listed in table 1. π is the radius of the different boundary layers, and β is the convective heat transfer 4|Page coefficient of the water, which is set at 136 W/m 2 K. A solution was generated for the analytical model at five different water temperatures. In the study done by Hayward et al, body heat loss was measured experimentally for different test subjects. Figure 6 shows the results from the analytical, Comsol, and Hayward studies of the heat loss rate of a human in varying water temperatures. In Comsol, the heat loss rate was taken to be an average over time due to the fact that the Comsol model is transient and the heat loss is changing slightly over time. 400 Sensitivity analysis Basal metabolic rate of a human varies greatly depending on environmental and physical conditions such as skin temperature, shivering rate, and physical activity. BMR is an important value in the model because metabolism and insulation are the two most important factors in survival time. In order to better understand the effects of BMR on survival time a sensitivity analysis was conducted where survival time was examined for several different rates of heat production. The findings are plotted here. Body heat loss versus water temperature Survival time vs. BMR 3 350 2.5 250 Survival time (hrs) Heat Flux (Watts) 300 200 150 100 50 2 1.5 1 0 -50 5 10 17.5 25 37 0.5 Water Temperature (Celsius) 0 Hayward Analytical 71.2 Model 104.3 137.4 170.5 203.6 Total metabolic heat production (Watts) Figure 6. Body heat loss for various water temperatures for a nude subject. Data for Hayward was taken from Thermal Balance and Survival Time Prediction of man in Cold Water [2]. The results from Figure 6 show a general agreement between our model and the analytical solution, as well as the case study conducted by Hayward et al. The data all have similar slopes and intersect at around 30 degrees Celsius. Figure 7. Sensitivity analysis of survival time versus BMR. The correlation is roughly linear. The results of this sensitivity analysis indicate that the survival time prediction varies greatly with BMR. This means that BMR must be chosen carefully for the model. Final Results The relationship between survival time and wetsuit thickness was examined by obtaining a plot of survival time versus wetsuit thickness with the model at a water temperature of 5 degrees Celsius. 5|Page Survival Time for different wetsuit thicknesses 6 Survival time(hrs) 5 4 3 2 1 0 0 3 4 5 7 9 11 Figure 10. Core body temperature drop over a span of 5 and ½ hours for a 11mm thick wetsuit and a water temperature of 5 degrees Celsius. Wetsuit thickness(mm) Figure 8. Survival time for different wetsuit thicknesses at a water temperature of 5 degrees Celsius. The plot in figure 8 indicates that thick wetsuits extend survival time. The graph appears to be roughly linear. Next, the 5mm thick wetsuit was tested in different water temperatures ranging from zero to 12.5 degrees Celsius. Survival time for different water temperatures 8 Survival time(hrs) 7 6 5 4 3 2 1 0 0 2.5 5 7.5 10 12.5 Water temp(Celsius) Figure 9. Survival time for different water temperatures for a 5mm thick wesuit. It is interesting that the temperature is initially increasing for a short time. This can be explained by understanding that this transient Comsol model is based largely off of literature where steady state analytical models are used. In models used to predict survival time in cold water, heat flow is often assumed to be one directional, flowing out from the body. Our model does not have this restriction, which results in a core temperature that can increase due to heat flow from the surrounding body regions. The slopes of both plots are what one would expect for the given conditions in the test. When wetsuit insulation thickness increases, survival time increases. Also, water temperature greatly affects survival time. Water temperature is in fact the greatest factor in survival time. Looking at figure 9, the slope of the curve is clearly increasing in the positive direction. This increase in slope is much more profound than in figure 8 where the plot is roughly linear. The fact that water temperature is a great factor in survival time is not a surprise. Heat transfer occurs across a temperature difference. Reduce that temperature difference, and heat transfer, or in this case heat loss from the body, is greatly reduced, which is what is seen in figure 9. 6|Page The effect of wetsuit thickness on survival time is slightly less profound than the effect of water temperature. However, wetsuit thickness unlike water temperature is a parameter that can be controlled depending on the situation, and so this is the parameter that is of interest. For a man not wearing a wetsuit in 5 degree water, survival time is only around 2 hours 15 minutes. Wearing an average sized wetsuit of around 8.5 mm thickness can double this survival time, as seen in the results in figure 8. For the search and rescue worker needing to know survival time, this model confirms that survival time can be estimated, and that suits provided for the shipwreck victims must be taken into consideration. As mentioned previously, wearing a wetsuit can easily double survival time, depending on the thickness of the suit. Rescue workers should take heed of this when considering the risk-benefit factors of a mission, such as situations where it may be beneficial to hold off a rescue mission until a later time. Conclusions Design Constraints To restate, a human body can only sustain so much cold before the hypothermia sets in. Wetsuits are made to help a person resist the cold by reducing the amount of heat lost to the water around him or her. Our study focuses on how long an unconscious person can survive in extremely cold waters before death is inevitable by modeling the human body as a cylinder and showing how the body reacts to the cold water environment over time. Conclusions drawn from this study can have a significant impact on matters of life and death. Survival suits are called such because they do exactly that, keep you from dying. Much discretion must be used in the production and specifications of these suits. There are currently several other much more advanced models of the human thermoregulatory system that can be used and have been used to predict the survival time for humans adrift at sea. Such models should be used in practice that have been rigorously peer reviewed and approved of by experts. Our model, while useful in understanding the general relationship between wetsuit thickness and survival time, as well as other factors such as water temperatures, is not the most qualified model for use in such important matters as saving a man’s life. If future work were to be conducted building upon the current model, there are several steps that could move the model into being one more worthy of recognition and use for biomedical applications. The first would be the move from a single to a multisegmented model. The human body is highly complex even with regards to basic functions like heat regulation. Arms, legs, head, torso and all other parts of the body have differing insulative layers of tissue as well as complex blood perfusion. Shivering occurs in some areas more predominantly than others as well. These would all be taken into account with a multi-segmented model. Comsol is a powerful tool that would allow great detail to be taken if such a model were to be pursued. Design Recommendations As stated previously, the survival time of a human immersed in cold water is important for two reasons. The first is for the specification of survival wetsuits for individuals working in different environments. The second is to aid in search and rescue missions where knowledge of a victim’s survival time allows people to make more informed decisions in planning a rescue. As far as specifications go, the model sheds light on the importance of different suits for different cold water environments. Situations with very cold waters will require suits that are significantly thicker than situations where water is not as cold. Specification of a suit for a certain situation cannot be oversimplified as there are many factors beyond water temperature that come into play. These may include proximity to shore or a rescue vessel, strength of the waters, size of the ship, and local weather conditions. 7|Page Appendix – EES Code used for analytical solution // Tom Barkley and Alexa Singer // Analytical Analysis of Temperature vs. Heat Loss // givens r_1=0.02816 [m] r_2=0.05816 [m] r_3=0.068163 [m] r_4=0.070163 [m] r_5=0.070963 [m] k_m=0.5 [W/m*K] k_f=0.19 [W/m*K] k_s1=0.45 [W/m*K] k_s2=0.24 [W/m*K] T_i=35+273.15 [K] // T_f is changing for parametric study L=4.19 [m] h= 136 [W/m^2*K] // finding the natural logs ln_1=0.605619 ln_2=0.158704 ln_3=0.028919 ln_4=0.011338 // equation (T_i-T_inf)/q= (ln_1/(2*pi*L*k_m)) + (ln_2/(2*pi*L*k_f)) + (ln_3/(2*pi*L*k_s1)) + (ln_4/(2*pi*L*k_s2)) + (1/(2*pi*r_5*L*h)) 8|Page References [1] Peter Tikuisis. "Prediction of Survival Time at Sea Based on Observed Body Cooling Rates." Aviation, Space, and Environmental Medicine 68.5 (1997): 44148. [2] J.S. Hayward, J.D. Eckerson, and M.L. Collis. "Thermal Balance and Survival Time Prediction of Man in Cold Water." Canadian Journal of Physiology and Pharmacology 53 (1975): 21-32. [3] C. Boutelier, L. Bougues, and J. Timbal. "Experimental Study of Convective Heat Transfer Coefficient for the Human Body in Water." Journal of Applied Physiology 42.1 (1977): 93-100. [4] F. Tarlochan, and S. Ramesh. "Heat Transfer Model for Predicting Survival Time in Cold Water Immersion." Biomedical Engineering Applications Basis Community 17.4 (2005): 159-65. [10] Ashim Datta, and Vineet Rakesh. An Introduction to Modeling of Transport Processes: Applications to Biomedical Systems. 1st ed. New York: Cambridge University Press, 2010. [11] P.F. Iampietro, et al. "Heat Production from Shivering." Journal of Applied Physiology 15.4 (1960). [12] D.S. Pal, and S. Pal. "Prediction of Temperature Profiles in the Human Skin and Subcutaneous Tissues." Journal of Mathematical Biology 28 (1990): 355-65. [13] Incropera, DeWitt et al. Fundamentals of heat and mass transfer. 6th ed. International Edition. John Wiley and Sons. 2007. [14] "Heat Capacity of Elastomers." Setaram Instrumentation. . Setaram Instrumentation K&P Technologies. [5] Zolfaghari, Alireza, and Mehdi Maerefat. "A New Simplified Thermoregulatory Bioheat Model for Evaluating Thermal Response of the Human Body to Transient Environments." Building and Environment 45.10 (2010): 2068-76. [6] Nuckton, Thomas J., et al. "Hypothermia from Prolonged Immersion: Biophysical Parameters of a Survivor." Journal of Emergency Medicine 22.4 (2002): 371-4. [7] Fanger, P.O. “Calculation of thermal comfort: introduction of a basic comfort equation.” ASHRAE Transactions. 73.2 (1997): III.4.1 – III.4.20. [8] Gagge, A.P., Stolwijk, Y. Nishi. “An effective temperature scale based on a simple model of human physiological regulatory response.” ASHRAE Transactions. 77.1 (1971): 247-262. [9] Ferreira, M. S., and J. I. Yanagihara. "A Transient Three-Dimensional Heat Transfer Model of the Human Body." International Communications in Heat and Mass Transfer 36.7 (2009): 718-24. 9|Page