Research Program Comprehensive studies in the field of traffic accident reconstruction Computer modeling of trauma and injury mechanisms Development of a database on the circumstances and mechanisms of injuries in traffic accident victims based on the extended post-mortem examinations and court files Studies on the metabolic interaction of ethanol with endogenous and exogenous substances Research on biochemical markers of metabolic abnormalities that precede death The use of cryopreserved hepatocytes to study the interaction of ethanol with toxic substances Development of spectroscopic methods of detection and determination of biocides in biological material Development of spectroscopic methods of detection and determination of psychoactive substances in biological material Polymorphism of STR loci; population data in the Poland, statistical evidence in paternity cases, determination of sibship Polymorphism of SNP loci- population data in the Poland TOPICS (labs and lectures, themes for examination questions) Thanatology The pathophysiology of death - definitions, causes and mechanisms of dying External examination of a corpse, evolution of death signs, decomposition processes Determination of the time of death Forensic autopsy procedures Forensic traumatology External injuries: abrasions, bruises (contusions) and wounds (lacerations) Typical consequences of blunt trauma, injuries from sharp and edged tools, shotgun wounds The pathology of wounds: mechanisms and classification, weapon identification Head, skull and brain injury mechanisms, intracranial haematomas Bone fracture mechanisms (head, chest, pelvis and long bones – diaphyseal and intraarticular) Transportation injuries Global burden of road traffic accidents, social and medical impact Pedestrian injuries (impact trajectories, typical injury mechanisms) Injuries to pedal cyclists and motorcyclists Patterns of injury of vehicle occupants (influence of safety devices, identification of the driver) Whiplash associated disorders General forensic pathology Classification of asphyxial deaths, differentiation of mechanical asphyxia mechanisms Drowning mechanisms and autopsy signs The effects of cold, fire burns and electrocution – post-mortem findings and diagnostics Carbon monoxide poisoning – toxicity, post-mortem findings and diagnostics Infanticide diagnostic, evidence of child abuse Forensic genetics Classical serological genetic markers Polymorphism of DNA: RFLP, VNTR, STR, SNP Technology of DNA typing markers: RFLP and AmFLP technologies DNA sample processing steps: extraction, amplification, separation and detection of PCR product Biological samples (preliminary research, confirmation research, the amelogenin sex-typing assay) DNA database, kinship and parentage testing Polymorphism of mtDNA and YSTR Forensic Toxicology Ethanol concentration calculations (Widmark formula, retrospective calculations) Determination of ethanol in breath air and blood samples (breath analyzers, laboratory methods) General classes of poisons, the most common drugs of abuse Methods of identification drugs of abuse (GC-MS, LC-MS, SPE, LLE) Multidirectional toxicological analysis, limitations of urine analyses