Title: Alert Worsening conditions And Report Early (AWARE): A patient education intervention to enhance the self-efficacy of hospitalized patients on recognition and reporting of acute deteriorating conditions Background: Acute deterioration in the general wards is an international health concern that requires urgent address. Much effort was concentrated on training and improving the skills of healthcare providers for the initial identification and management of deteriorating patients based on objective physiological metrics. To improve the current rapid response system, recent literature have credited patient reports as the gold standard in measuring symptoms and identified the need to consider patients as 1) the first recognizer in patient deterioration and; 2) trigger of the response system even before the abnormal physiological signs are prominent and detectable by healthcare providers. However, the difficulties and uncertainties encountered by patients in recognizing their symptoms as serious could extend delays in the timely escalation of care. Objective: This study aimed to develop, implement and test the effectiveness of a patient education intervention in enhancing the self-efficacy of patients to recognize and report acute deteriorating conditions. Methods: Using cluster randomization, acute care general wards were randomized to the experimental and control groups. Convenience sampling was applied to recruit the 67 adult patients from an acute hospital. 34 patients from the experimental group received a 30-minute patient education intervention on Alert Worsening conditions and Report Early (AWARE) using the ABCDE (Airway obstruction, Breathlessness, Cold, Dizziness, Extreme pain, and Expel and Excrete blood) mnemonics on recognition and reporting of acute deteriorating conditions while 33 patients in the control group received routine care only. Levels of self-efficacy to recognize and report symptoms were measured before and after the intervention using a 10-item Self-Efficacy Response Scale (SERS) questionnaire. Results: Both groups showed significant improvements in their overall posttest mean scores compared to pretest. However, levels of self-efficacy reported by the experimental group were significantly higher than the control group (p < 0.0001). Conclusion: A one-on-one patient education intervention that utilized the ABCDE mnemonics has enhanced the self-efficacy of patients to recognize and report acute deterioration. Patient engagement through patient education could be further explored for purposes of implementation as part of the present ward routine care and included in the current rapid response system to enhance patient safety measures and reduce the incidences of hospital mortality and morbidity in the general wards. Figures: Figure 1: ABCDE mnemonic handout in the AWARE intervention p < 0.0001 60 51.24 p < 0.05 Mean Score 50 40 35.76 36.88 34.45 Pre-test 30 Post-test 20 10 0 Control Experimental Figure 2: Pre-posttest mean scores in recognizing and reporting worsening conditions