Monday
Protein Synthesis
Tuesday
Protein synthesis
Wednesday
Protein synthesis
Thursday
Protein synthesis
Friday
Protein synthesis
Pretest ~20-30 min
Experimental history
leading to the
understanding of
protein synthesis.
Introduce RNA
Transcription and
mRNA processing
Translation
Types of mutations
effecting protein
synthesis
Activity:
http://serendip.brynma
wr.edu/sci_edu/waldro
n/pdf/TranscriptionTra
nslationProtocol.pdf
Activity:
http://serendip.brynmaw
r.edu/sci_edu/waldron/p
df/TranscriptionTranslati
onProtocol.pdf
Causes of mutations.
Understanding the
environmental
impacts on mutations
Mutation telephone
activity; practice
sheets
Read text on
transcription
Overview meiosis.
Translation reading
One gene one
polypeptide activity:
video
Meiosis
Allow students to
understand the
concept of meiosis.
Compare asexual
and sexual
reproduction.
Make charts
showing the different
stages of meiosis.
Lab activity in which
they experiment with
meiosis—can be
through online
simulations.
Quiz/test.
Relate meiosis to
inheritance, especially
in different domains
(e.g. plants, animals,
bacteria. Compare
meiosis and mitosis
(covered in earlier
unit). Explain
recombination.
Question students;
activities (practice
worksheets/video/onlin
e simulation);
discussions; quiz; test
Read chapter as
well as complete
handout, detailing
what happens at
each stage of
meiosis.
Human
development:
Reproduction
Human reproduction
and development
Quiz on previous
two weeks~20 min
Introduction to the
reproductive system
Video
Role of probability in
inheritance
Patterns of
Inheritance
Patterns of
Inheritance
Describe how Mendel’s
laws of segregation and
independent assortment
can be observed through
patterns of inheritance
(e.g., dihybrid crosses).
Use a Punnett Square to
determine the
probabilities for genotype
and phenotype
combinations in
monohybrid crosses.
Study dominance
relations/ multiple
effects of single
genes/ interaction
between gene pairs
and it’s phenotypic
effects.
Overview meiosis
and patterns of
inheritance and
genetic variation.
Environmental effects
on phenotypes, other
forms of inheritance
(mitochondrial).
Limitations of
mendelian genetics
(multifactorial
inheritance/complex
diseases)
Activity based on
probability/punett square
Long-term project:
ask students to
conduct their own
plant breeding
experiments using
pure breeding
species of a flowering
plant, followed by a
lab report.
Ask students to
hypothesize results of
activity; draw conclusions;
interpret information; ask
clarifying questions
Human development:
Reproduction
Lab: Uterus dissection
(http://cibt.bio.cornell.e
du/labs_and_activities/
images/Uteri_Dissectio
n.pdf)
Homework activity:
compare bovine an
dhuman fetal
development
(http://cibt.bio.cornell.e
du/labs_and_activities/
images/FetalDevelopm
ent.pdf)
Simulation activity:
effects of factors such
as x—rays on DNA
structure
Video on Mendel’s
pea experiment/
simulation on
recombination/
Class
activity(http://geneed.
nlm.nih.
gov/topic_subtopic.ph
p?tid=5&sid=8
Genetics
Genetics
Genetics
Understand inheritance,
crossing
over/recombination at
the chromosomal level.
Karyotyping. Overview
Morgan’s experiments
with flies.
Linkage mapping (xlinked, y-linked
genes). Pedigree
analysis. Human
genetic disorders. In
heritance patterns of
autosomal/sex-linked
diseases, as well as
effects of changes in
chromosomal
numbers
Prospects in human
genetics: phenotypic
treatments, genetic
counseling, prenatal
diagnosis, preimplantation
diagnosis, and
abortion.
Karyotyping simulation
activity
(http://www.biology.ariz
ona.edu/Human_Bio/act
ivities/karyotyping/karyo
typing.html)
Complete questions on
simulation (handout).
Practice linkage
mapping using
Morgan’s flies
examples.
identify an inherited
Work in groups for
presentation on
selected genetic
disorders
Work on
presentations for next
class
genetic disorder, and
research what
mutations led to the
development of this
disorder as well as
how it is inherited
Genetics
Genetic engineering
Genetic engineering
Students present
their research on
selected disease
topics
Restriction enzymes,
intro to major
techniques used in
biotechnology
Indepth analysis of PCR
and gel electrophoresis
Students complete
peer evaluation
forms. Present their
research
Hook: “law and order”
Video: human genome
project
Lab: Students carry out
gel electrophoresis
Field Trip: City lab
Genetic engineering
Overview and
applications of
genetic engineering:
GMO, cloning, etc,
and ethics in genetics
Video/discussion/acti
vity
Unit followed by class
test.